List of works - Francesco Bemporad

Protein misfolded oligomers: experimental approaches, mechanism of formation, and structure-toxicity relationships

scientific article published on March 2012

Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins

scientific article

Evidence for a mechanism of amyloid formation involving molecular reorganisation within native-like precursor aggregates

scientific article published in August 2005

Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase

scientific article

Amyloid formation of a protein in the absence of initial unfolding and destabilization of the native state.

scientific article published on 16 September 2005

Sequence and structural determinants of amyloid fibril formation

scientific article published on September 2006

Structure, conformational stability, and enzymatic properties of acylphosphatase from the hyperthermophile Sulfolobus solfataricus

scientific article

"Native-like aggregation" of the acylphosphatase from Sulfolobus solfataricus and its biological implications

scientific article published on 16 July 2009

The degree of structural protection at the edge beta-strands determines the pathway of amyloid formation in globular proteins

scientific article published on 12 March 2008

Rapid oligomer formation of human muscle acylphosphatase induced by heparan sulfate

scientific article published on 22 April 2012

Structural and dynamics characteristics of acylphosphatase from Sulfolobus solfataricus in the monomeric state and in the initial native-like aggregates

scientific article published on 11 March 2010

Exploring the mechanism of formation of native-like and precursor amyloid oligomers for the native acylphosphatase from Sulfolobus solfataricus.

scientific article published in June 2006

Characterizing intermolecular interactions that initiate native-like protein aggregation

scientific article published on 5 June 2012

A model for the aggregation of the acylphosphatase from Sulfolobus solfataricus in its native-like state

scientific article published on 12 September 2008

Biological function in a non-native partially folded state of a protein

scientific article published on May 2008

The folding process of acylphosphatase from Escherichia coli is remarkably accelerated by the presence of a disulfide bond.

scientific article published on 30 April 2008

The Folding process of Human Profilin-1, a novel protein associated with familial amyotrophic lateral sclerosis

scientific article published on 31 July 2015

¹H, ¹³C and ¹⁵N resonance assignments of human muscle acylphosphatase

scientific article

Mutations of Profilin-1 Associated with Amyotrophic Lateral Sclerosis Promote Aggregation Due to Structural Changes of Its Native State

scientific article published on 27 August 2015

Studying the folding process of the acylphosphatase from Sulfolobus solfataricus. A comparative analysis with other proteins from the same superfamily

scientific article published in July 2004

A complex equilibrium among partially unfolded conformations in monomeric transthyretin

scientific article published in July 2014

Edge strand engineering prevents native-like aggregation in Sulfolobus solfataricus acylphosphatase

scientific article

NMR characterization of the conformational fluctuations of the human lymphocyte function-associated antigen-1 I-domain

scientific article published on 5 September 2014

Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2-microglobulin

scientific article published on 18 March 2016

Structure and dynamics of the integrin LFA-1 I-domain in the inactive state underlie its inside-out/outside-in signaling and allosteric mechanisms

scientific article published on 12 March 2015

Amyloid fibril formation by a normally folded protein in the absence of denaturants and agitation

scientific article published on 20 September 2013

Preliminary characterization of two different crystal forms of acylphosphatase from the hyperthermophile archaeon Sulfolobus solfataricus

scientific article

Probing conformational changes of monomeric transthyretin with second derivative fluorescence

scientific article published on 29 July 2019

Insight into the Folding and Dimerization Mechanisms of the N-Terminal Domain from Human TDP-43

scientific article published on 29 August 2020

Stability of an aggregation-prone partially folded state of human profilin-1 correlates with aggregation propensity

scientific article published on 14 May 2018

Pathways of Amyloid Formation

Conversion of the Native N-Terminal Domain of TDP-43 into a Monomeric Alternative Fold with Lower Aggregation Propensity

scientific article published in 2022

Identification of Novel 1,3,5-Triphenylbenzene Derivative Compounds as Inhibitors of Hen Lysozyme Amyloid Fibril Formation

scientific article published on 07 November 2019

Capturing Aβ42 aggregation in the cell

scientific article published in Journal of Biological Chemistry

List of works by Francesco Bemporad

Protein misfolded oligomers: experimental approaches, mechanism of formation, and structure-toxicity relationships

Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins

Evidence for a mechanism of amyloid formation involving molecular reorganisation within native-like precursor aggregates

Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase

Amyloid formation of a protein in the absence of initial unfolding and destabilization of the native state.

Sequence and structural determinants of amyloid fibril formation

Structure, conformational stability, and enzymatic properties of acylphosphatase from the hyperthermophile Sulfolobus solfataricus

"Native-like aggregation" of the acylphosphatase from Sulfolobus solfataricus and its biological implications

The degree of structural protection at the edge beta-strands determines the pathway of amyloid formation in globular proteins

Rapid oligomer formation of human muscle acylphosphatase induced by heparan sulfate

Structural and dynamics characteristics of acylphosphatase from Sulfolobus solfataricus in the monomeric state and in the initial native-like aggregates

Exploring the mechanism of formation of native-like and precursor amyloid oligomers for the native acylphosphatase from Sulfolobus solfataricus.

Characterizing intermolecular interactions that initiate native-like protein aggregation

A model for the aggregation of the acylphosphatase from Sulfolobus solfataricus in its native-like state

Biological function in a non-native partially folded state of a protein

The folding process of acylphosphatase from Escherichia coli is remarkably accelerated by the presence of a disulfide bond.

The Folding process of Human Profilin-1, a novel protein associated with familial amyotrophic lateral sclerosis

¹H, ¹³C and ¹⁵N resonance assignments of human muscle acylphosphatase

Mutations of Profilin-1 Associated with Amyotrophic Lateral Sclerosis Promote Aggregation Due to Structural Changes of Its Native State

Studying the folding process of the acylphosphatase from Sulfolobus solfataricus. A comparative analysis with other proteins from the same superfamily

A complex equilibrium among partially unfolded conformations in monomeric transthyretin

Edge strand engineering prevents native-like aggregation in Sulfolobus solfataricus acylphosphatase

NMR characterization of the conformational fluctuations of the human lymphocyte function-associated antigen-1 I-domain

Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2-microglobulin

Structure and dynamics of the integrin LFA-1 I-domain in the inactive state underlie its inside-out/outside-in signaling and allosteric mechanisms

Amyloid fibril formation by a normally folded protein in the absence of denaturants and agitation

Preliminary characterization of two different crystal forms of acylphosphatase from the hyperthermophile archaeon Sulfolobus solfataricus

Probing conformational changes of monomeric transthyretin with second derivative fluorescence

Insight into the Folding and Dimerization Mechanisms of the N-Terminal Domain from Human TDP-43

Stability of an aggregation-prone partially folded state of human profilin-1 correlates with aggregation propensity

Pathways of Amyloid Formation

Conversion of the Native N-Terminal Domain of TDP-43 into a Monomeric Alternative Fold with Lower Aggregation Propensity

Identification of Novel 1,3,5-Triphenylbenzene Derivative Compounds as Inhibitors of Hen Lysozyme Amyloid Fibril Formation

Capturing Aβ42 aggregation in the cell