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List of works by Hendrik Jan Thibaut

9-Arylpurines as a novel class of enterovirus inhibitors.

scientific article

9-Norbornyl-6-chloropurine (NCP) induces cell death through GSH depletion-associated ER stress and mitochondrial dysfunction

scientific article published on 7 June 2016

A Novel 9-Arylpurine Acts as a Selective Inhibitor of In Vitro Enterovirus Replication Possibly by Targeting Virus Encapsidation

scientific article published in 2010

A novel, broad-spectrum inhibitor of enterovirus replication that targets host cell factor phosphatidylinositol 4-kinase IIIβ.

scientific article published on 29 July 2013

A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate

scientific article published on 01 December 2020

Animal models for COVID-19

scientific article published on 23 September 2020

Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68.

scientific article

Binding of glutathione to enterovirus capsids is essential for virion morphogenesis

scientific article (publication date: April 2014)

Broad-range inhibition of enterovirus replication by OSW-1, a natural compound targeting OSBP.

scientific article

Bypassing pan-enterovirus host factor PLA2G16

scientific article published on 18 July 2019

Combating enterovirus replication: State-of-the-art on antiviral research

scientific article (publication date: 2012)

Efficient synthesis and anti-enteroviral activity of 9-arylpurines

scientific article published on 17 January 2012

Enterovirus D68 receptor requirements unveiled by haploid genetics.

scientific article published on 19 January 2016

Fitness and virulence of a coxsackievirus mutant that can circumnavigate the need for phosphatidylinositol 4-kinase class III beta

scientific article

H1PVAT is a novel and potent early-stage inhibitor of poliovirus replication that targets VP1.

scientific article

Hydantoin: The mechanism of its in vitro anti-enterovirus activity revisited

scientific article published on 30 July 2016

Identification of the Cell-Surface Protease ADAM9 as an Entry Factor for Encephalomyocarditis Virus

scientific article published on 13 August 2019

Inflammatory rather than infectious insults play a role in exocrine tissue damage in a mouse model for coxsackievirus B4-induced pancreatitis

scientific article published in April 2009

Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence

scientific article published on 01 January 2019

Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein

scientific article

Limited evolution of the yellow fever virus 17d in a mouse infection model

scientific article published on 01 January 2019

Molecular biology and inhibitors of hepatitis A virus

scientific article published on 30 May 2013

Mutations in the nonstructural protein 3A confer resistance to the novel enterovirus replication inhibitor TTP-8307.

scientific article published on 23 February 2009

Novel 9-Arylpurines, as Selective Inhibitors of In Vitro Enterovirus Replication

scientific article published in 2009

PLA2G16 represents a switch between entry and clearance of Picornaviridae

scientific journal article

Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus ⬇️

scientific article published on 28 December 2017

STAT2 signaling as double-edged sword restricting viral dissemination but driving severe pneumonia in SARS-CoV-2 infected hamsters

scientific article published on 24 April 2020

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

scientific article published on 17 November 2020

Selective serotonin reuptake inhibitor fluoxetine inhibits replication of human enteroviruses B and D by targeting viral protein 2C.

scientific article published on 18 January 2013

Sialic acid-dependent cell entry of human enterovirus D68.

scientific article

Synthesis and SAR of 9-Arylpurines as Novel Inhibitors of Enterovirus Replication

scientific article published in 2009

The life cycle of non-polio enteroviruses and how to target it

scientific article published on 01 June 2018

The microRNA-221/-222 cluster balances the antiviral and inflammatory response in viral myocarditis.

scientific article published on 22 July 2015

Toward antiviral therapy/prophylaxis for rhinovirus-induced exacerbations of chronic obstructive pulmonary disease: challenges, opportunities, and strategies

scientific article published on 21 September 2015

Towards the design of combination therapy for the treatment of enterovirus infections

scientific article published on 3 April 2011

Viral engagement with host receptors blocked by a novel class of tryptophan dendrimers that targets the 5-fold-axis of the enterovirus-A71 capsid

scientific article published on 09 May 2019

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