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List of works by Gerd Folkers

A fast and inexpensive method for N-terminal fluorescein-labeling of peptides

scientific article published on 01 March 1998

A molecular dynamics study of reovirus attachment protein sigma1 reveals conformational changes in sigma1 structure

scientific article published on June 2004

A new method for quantitative determination of tritium-labeled nucleoside kinase products adsorbed on DEAE-cellulose

scientific article published on 01 August 1996

A new tool for real-time pain assessment in experimental and clinical environments

scientific article

A pseudoreceptor modelling study of the varicella-zoster virus and human thymidine kinase binding sites.

scientific article published in December 1995

A spectrophotometric assay for quantitative determination of kcat of herpes simplex virus type 1 thymidine kinase substrates.

scientific article published in August 2001

A transferred NOE study of a tricyclic analog of acyclovir bound to thymidine kinase

scientific article published on 01 October 1996

An analysis of the helix-to-strand transition between peptides with identical sequence.

scientific article published in November 2000

Application of QSAR analysis to organic anion transporting polypeptide 1a5 (Oatp1a5) substrates

scientific article published in January 2005

Beta-amino acid scan of a class I major histocompatibility complex-restricted alloreactive T-cell epitope

scientific article published on 07 May 2001

Binding mode prediction of cytochrome p450 and thymidine kinase protein-ligand complexes by consideration of water and rescoring in automated docking.

scientific article published in April 2005

Binding of rationally designed non-natural peptides to the human leukocyte antigen HLA-B*2705.

scientific article

Bovine pancreatic polypeptide (bPP) undergoes significant changes in conformation and dynamics upon binding to DPC micelles

scientific article

Calpain-1 Regulates Bax and Subsequent Smac-dependent Caspase-3 Activation in Neutrophil Apoptosis

scientific article published in Journal of Biological Chemistry

Changes in self-perceived role identity modulate pain perception.

scientific article published on 22 May 2007

Combinatorial chemistry by ant colony optimization.

scientific article

Comparison of the crystal structures of the human manganese superoxide dismutase and the homologous Aspergillus fumigatus allergen at 2-A resolution

scientific article

Compulsory order of substrate binding to herpes simplex virus type 1 thymidine kinase. A calorimetric study.

scientific article published in May 2000

Computational Methods Facilitate the Assignment of Protein Functions

scientific article published on 01 November 2001

Corrigendum to “The Swiss Canine Cancer Registry: A Retrospective Study on the Occurrence of Tumours in Dogs in Switzerland from 1955 to 2008” [J Comp Pathol 152 (2–3) (2015) 161–171]

scientific article published in July 2015

Critical Thinking in Education and Research-Why and How?

scientific article published on 15 October 2018

Drug resistance of herpes simplex virus type 1--structural considerations at the molecular level of the thymidine kinase.

scientific article published in July 1998

Estimation of blood-brain barrier crossing of drugs using molecular size and shape, and H-bonding descriptors.

scientific article published in January 1998

Exhaustive proteome mining for functional MHC-I ligands

scientific article published on 17 June 2013

Fine specificity of antigen binding to two class I major histocompatibility proteins (B*2705 and B*2703) differing in a single amino acid residue.

scientific article published in September 1997

Heat pain threshold and tolerance show no left-right perceptual differences at complementary sites of the human forearm.

scientific article

Highly purified recombinant varicella Zoster virus thymidine kinase is a homodimer.

scientific article published in April 2000

Homology modelling and docking studies on Varicella Zoster Virus Thymidine kinase

scientific article published in April 2003

How much reproducibility do we need in human and veterinary pathology?

scientific article published on 4 December 2014

Immunological and structural analysis of IgE-mediated cross-reactivity between manganese superoxide dismutases.

scientific article

Incidence of drug-induced liver injury in medical inpatients.

scientific article published on 23 February 2005

Increased radiation toxicity by enhanced apoptotic clearance of HL-60 cells in the presence of the pentapeptide thymopentin, which selectively binds to apoptotic cells.

scientific article published in March 2004

Integrated homology modelling and X-ray study of herpes simplex virus I thymidine kinase: a case study.

scientific article published on January 1997

Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine

scientific article

N-glycan structures and N-glycosylation sites of mouse soluble intercellular adhesion molecule-1 revealed by MALDI-TOF and FTICR mass spectrometry

scientific article

Nonapeptide analogues containing (R)-3-hydroxybutanoate and beta-homoalanine oligomers: synthesis and binding affinity to a class I major histocompatibility complex protein.

scientific article published on July 1999

Oligonucleotide-directed mutagenesis and subsequent expression of the corresponding recombinant proteins without changing the bacterial vector system.

scientific article

On the role of thymopoietins in cell proliferation. Immunochemical evidence for new members of the human thymopoietin family

scientific article (publication date: June 1999)

Patupilone acts as radiosensitizing agent in multidrug-resistant cancer cells in vitro and in vivo.

scientific article published on February 2005

Placebo-mediated, Naloxone-sensitive suggestibility of short-term memory performance.

scientific article published on 26 January 2011

Pleasure-related analgesia activates opioid-insensitive circuits.

scientific article published in March 2011

Protonation states of methionine aminopeptidase and their relevance for inhibitor binding and catalytic activity

scientific article published on 26 September 2003

Quality of Animal Experiments in Anti-Angiogenic Cancer Drug Development--A Systematic Review

scientific article

Random chemistry as a new tool for the generation of small compound libraries: development of a new acetylcholinesterase inhibitor

scientific article

Random chemistry as a new tool for the generation of small-compound libraries

scientific article

Recombinant expression and biochemical characterization of the unique elongating beta-ketoacyl-acyl carrier protein synthase involved in fatty acid biosynthesis of Plasmodium falciparum using natural and artificial substrates.

scientific article published on 8 February 2006

Relevance relations for the concept of reproducibility

scientific article published on 19 February 2014

Scrutinizing MHC-I binding peptides and their limits of variation

scientific article

Secondary structure prediction of adenylate kinase by circular dichroism spectroscopy of synthetic peptides

scientific article published on 01 April 1995

Site-directed mutagenesis of herpes simplex virus type 1 thymidine kinase opposes the importance of amino acid positions 251, 321 and 348 for selective recognition of substrate analogs.

scientific article

Strongly altered receptor binding properties in PP and NPY chimeras are accompanied by changes in structure and membrane binding

scientific article published on 01 June 2005

Structure of a type II thymidine kinase with bound dTTP

scientific journal article

Structure-activity relationships of cannabinoids: a joint CoMFA and pseudoreceptor modelling study

scientific article published on 01 May 1997

Substrate diversity of herpes simplex virus thymidine kinase. Impact Of the kinematics of the enzyme.

scientific article published in November 1999

Swiss Canine Cancer Registry 1955-2008: Occurrence of the Most Common Tumour Diagnoses and Influence of Age, Breed, Body Size, Sex and Neutering Status on Tumour Development.

scientific article published on 9 July 2016

Swiss Feline Cancer Registry 1965-2008: the Influence of Sex, Breed and Age on Tumour Types and Tumour Locations

scientific article

Swiss Feline Cancer Registry: A Retrospective Study of the Occurrence of Tumours in Cats in Switzerland from 1965 to 2008.

scientific article

Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)-methanocarbathymine

scientific article published on November 2003

Synthesis and biological evaluation of iodinated and fluorinated 9-(2-hydroxypropyl) and 9-(2-hydroxyethoxy)methyl purine nucleoside analogues

scientific article published on December 2003

Synthesis, 18F-radiolabelling and biological evaluations of C-6 alkylated pyrimidine nucleoside analogues

scientific article published in January 2004

TP5 triggers signal transduction involving mitogen activated protein kinases in monocytes

scientific article published on 01 January 1999

Temperature-Dependent NMR and CD Spectra ofβ-Peptides: On the Thermal Stability ofβ-Peptide Helices - Is the Folding Process ofβ-Peptides Non-cooperative?

The Swiss Canine Cancer Registry: a retrospective study on the occurrence of tumours in dogs in Switzerland from 1955 to 2008.

scientific article published on February 2015

The crystal structure of Aspergillus fumigatus cyclophilin reveals 3D domain swapping of a central element.

scientific article published in February 2006

The crystal structure of PfFabZ, the unique beta-hydroxyacyl-ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum.

scientific article published on June 2005

The effect of substrate binding on the conformation and structural stability of Herpes simplex virus type 1 thymidine kinase

scientific article

The rational of catalytic activity of herpes simplex virus thymidine kinase. a combined biochemical and quantum chemical study.

scientific article

Thermodynamic stability of HLA-B*2705. Peptide complexes. Effect of peptide and major histocompatibility complex protein mutations.

scientific article published on September 2000

Thermodynamics of the interaction between oxytocin and its myometrial receptor in sheep: A stepwise binding mechanism

scientific article published on 07 July 2014

Use of fluorescence polarization to monitor MHC-peptide interactions in solution

scientific article published on 01 September 2001

Vaccines and their transfection potency

scientific article published on 01 April 1999