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List of works by Peter M Heegaard

A pig model of acute Staphylococcus aureus induced pyemia

scientific article published on 27 March 2009

A robust quantitative solid phase immunoassay for the acute phase protein C-reactive protein (CRP) based on cytidine 5'-diphosphocholine coupled dendrimers.

scientific article published on 21 February 2009

AU Content in the MicroRNA Sequence Influences its Stability after Heat Treatment

scientific article published on 01 January 2019

Adjuvants and delivery systems in veterinary vaccinology: current state and future developments ⬇️

scientific article published on December 19, 2010

Analysis of the acute phase responses of serum amyloid a, haptoglobin and type 1 interferon in cattle experimentally infected with foot-and-mouth disease virus serotype O.

scientific article

Animal Models for Influenza A Virus Infection Incorporating the Involvement of Innate Host Defenses: Enhanced Translational Value of the Porcine Model

scientific article published on 01 December 2018

Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs

scientific article published on 30 October 2017

Bovine colostrum improves intestinal function following formula-induced gut inflammation in preterm pigs.

scientific article

Brief report: biomarkers of aortic vascular prosthetic graft infection in a porcine model with Staphylococcus aureus

scientific article published on 13 July 2010

Certain dietary carbohydrates promote Listeria infection in a guinea pig model, while others prevent it

article

Characterisation of new monoclonal antibodies reacting with prions from both human and animal brain tissues.

scientific article published on 25 July 2008

Characterization and differentiation of equine experimental local and early systemic inflammation by expression responses of inflammation-related genes in peripheral blood leukocytes

scientific article

Concurrent host-pathogen gene expression in the lungs of pigs challenged with Actinobacillus pleuropneumoniae

scientific article published on 28 May 2015

Delayed development of systemic immunity in preterm pigs as a model for preterm infants.

scientific article

Dendrimer Effects on Peptide and Protein Fibrillation

scientific article published on 01 August 2007

Dendrimers destabilize proteins in a generation-dependent manner involving electrostatic interactions.

scientific article

Dendrimers for vaccine and immunostimulatory uses. A review.

scientific article

Development and evaluation of a mixed long-chain lipopolysaccharide based ELISA for serological surveillance of infection with Actinobacillus pleuropneumoniae serotypes 2, 6 and 12 in pig herds

scientific article published on 01 October 2003

Doxorubicin-Induced Gut Toxicity in Piglets Fed Bovine Milk and Colostrum

article

Dynamic expression of leukocyte innate immune genes in whole blood from horses with lipopolysaccharide-induced acute systemic inflammation

scientific article published on 16 June 2015

Early pathogenesis and inflammatory response in experimental bovine mastitis due to Streptococcus uberis

scientific article published on 01 February 2003

Effect of different hapten-carrier conjugation ratios and molecular orientations on antibody affinity against a peptide antigen.

scientific article published on 6 March 2006

Effect of moving dairy cows at different stages of labor on behavior during parturition

scientific article published on 16 January 2013

Effects of Roux-en-Y gastric bypass on fasting and postprandial inflammation-related parameters in obese subjects with normal glucose tolerance and in obese subjects with type 2 diabetes

scientific article

Efficacy and safety of simultaneous vaccination with two modified live virus vaccines against porcine reproductive and respiratory syndrome virus types 1 and 2 in pigs

scientific article published on 27 November 2017

Enhancement of muramyldipeptide (MDP) immunostimulatory activity by controlled multimerization on dendrimers

scientific article published on 25 August 2011

Experimental anal infection of rainbow trout with Flavobacterium psychrophilum: A novel challenge model

scientific article published on 11 September 2018

Expression of innate immune response genes in liver and three types of adipose tissue in cloned pigs.

scientific article

Expression of selected genes isolated from whole blood, liver and obex in lambs with experimental classical scrapie and healthy controls, showing a systemic innate immune response at the clinical end-stage

article

Extensive changes in innate immune gene expression in obese Göttingen minipigs do not lead to changes in concentrations of circulating cytokines and acute phase proteins

scientific article published on 25 September 2013

Fetal lipopolysaccharide exposure modulates diet-dependent gut maturation and sensitivity to necrotising enterocolitis in pre-term pigs.

scientific article

Gene Expression Analysis of the IPEC-J2 Cell Line: A Simple Model for the Inflammation-Sensitive Preterm Intestine

article

Genetic and biological characterisation of an avian-like H1N2 swine influenza virus generated by reassortment of circulating avian-like H1N1 and H3N2 subtypes in Denmark.

scientific article published on 18 September 2013

Genetic and biological characterization of a Porcine Reproductive and Respiratory Syndrome Virus 2 (PRRSV-2) causing significant clinical disease in the field.

scientific article published on 3 October 2017

Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals

scientific article

Hepatic expression of inflammatory genes and microRNAs in pigs with high "cholesteryl ester transfer protein" (CETP) activity.

scientific article published on 30 May 2016

Heterogeneity in copper and glycan content of ceruloplasmin in human serum differs in health and disease

scientific article published on 01 June 1988

High-fat but not sucrose intake is essential for induction of dyslipidemia and non-alcoholic steatohepatitis in guinea pigs

scientific article published on 09 August 2016

Host Response to Porcine Strains of Escherichia coli in a Novel Pyelonephritis Model ⬇️

scientific article published on December 14, 2010

IFN-λ and microRNAs are important modulators of the pulmonary innate immune response against influenza A (H1N2) infection in pigs

scientific article published on 20 April 2018

ITIH4 (inter-alpha-trypsin inhibitor heavy chain 4) is a new acute-phase protein isolated from cattle during experimental infection

scientific article

Increased Intestinal Inflammation and Digestive Dysfunction in Preterm Pigs with Severe Necrotizing Enterocolitis

scientific article published on 24 December 2016

Infection-induced coronary dysfunction and systemic inflammation in piglets are dampened in hypercholesterolemic milieu.

scientific article published on 25 February 2011

Innate immune responses of calves during transient infection with a noncytopathic strain of bovine viral diarrhea virus.

scientific article published on March 2004

Isolation of Actinobacillus pleuropneumoniae serotype 2 by immunomagnetic separation

scientific article published on 01 March 2001

Johne's disease in cattle is associated with enhanced expression of genes encoding IL-5, GATA-3, tissue inhibitors of matrix metalloproteinases 1 and 2, and factors promoting apoptosis in peripheral blood mononuclear cells.

scientific article

Lipidated α-peptide/β-peptoid hybrids with potent anti-inflammatory activity.

scientific article published on 29 December 2014

Local osteogenic expression of cyclooxygenase-2 and systemic response in porcine models of osteomyelitis

scientific article published on 14 January 2012

Loss of prion protein induces a primed state of type I interferon-responsive genes.

scientific article

Low concentration of serum immunoglobulin G is associated with pre-weaning diarrhea in young mink kits (Neovison vison)

scientific article published on 10 June 2019

MBL1 genotypes in wild boar populations from Sweden, Austria, the Czech Republic, and Japan.

scientific article published on 4 June 2012

Marked induction of IL-6, haptoglobin and IFNgamma following experimental BRSV infection in young calves

scientific article published in February 2005

Milk diets influence doxorubicin-induced intestinal toxicity in piglets.

scientific article published on 21 July 2016

Mink (Neovison vison) kits with pre-weaning diarrhea have elevated serum amyloid A levels and intestinal pathomorphological similarities with New Neonatal Porcine Diarrhea Syndrome

Modelling severe Staphylococcus aureus sepsis in conscious pigs: are implications for animal welfare justified?

scientific article published on 16 February 2016

Modulation of cytokine mRNA expression in pharyngeal epithelial samples obtained from cattle infected with foot-and-mouth disease virus.

scientific article published on 24 August 2011

Natural Pig Plasma Immunoglobulins Have Anti-Bacterial Effects: Potential for Use as Feed Supplement for Treatment of Intestinal Infections in Pigs.

scientific article published on 29 January 2016

Necrotizing Enterocolitis in Preterm Pigs Is Associated with Increased Density of Intestinal Mucosa-Associated Bacteria Including Clostridium perfringens.

scientific article published on 7 August 2015

Non-invasive assessment of in-vitro embryo quality to improve transfer success

scientific article

Novel Adjuvants and Immunomodulators for Veterinary Vaccines.

scientific article published on January 2016

Novel porcine model of implant-associated osteomyelitis: A comprehensive analysis of local, regional, and systemic response.

scientific article published on 13 December 2016

Optimal combinations of acute phase proteins for detecting infectious disease in pigs.

scientific article

Organization and biology of the porcine serum amyloid A (SAA) gene cluster: isoform specific responses to bacterial infection

scientific article

Orosomucoid expression profiles in liver, adipose tissues and serum of lean and obese domestic pigs, Göttingen minipigs and Ossabaw minipigs.

scientific article published on 27 November 2012

Oxidation reduces the fibrillation but not the neurotoxicity of the prion peptide PrP106-126

scientific article published on 13 July 2007

Passive immunisation, an old idea revisited: Basic principles and application to modern animal production systems.

scientific article published on 26 April 2016

Pathogenicity of Cryptosporidium parvum—evaluation of an animal infection model

scientific article published on 01 April 2003

Pathogenicity of three genetically diverse strains of PRRSV Type 1 in specific pathogen free pigs.

scientific article published on 16 May 2017

Pathology, tissue metalloproteinase transcription and haptoglobin responses in mice after experimental challenge with different isolates of Pasteurella multocida obtained from cases of porcine pneumonia.

scientific article published on 8 March 2011

Pig-major acute phase protein and haptoglobin serum concentrations correlate with PCV2 viremia and the clinical course of postweaning multisystemic wasting syndrome.

scientific article published on 13 March 2009

Porcine blood mononuclear cell cytokine responses to PAMP molecules: comparison of mRNA and protein production.

scientific article

Prion-Specific Antibodies Produced in Wild-Type Mice.

scientific article

Profiling microRNAs in lung tissue from pigs infected with Actinobacillus pleuropneumoniae

scientific article

Protective effect of in-feed specific IgM towards Yersinia ruckeri in rainbow trout

scientific article published on 10 August 2019

Pseudoalteromonas strains are potent immunomodulators owing to low-stimulatory LPS.

scientific article published on 13 August 2012

Purified natural pig immunoglobulins can substitute dietary zinc in reducing piglet post weaning diarrhoea.

scientific article published on 04 February 2017

Quantitative immunoassay for mink immunoglobulin in serum and milk.

scientific article

Seroprevalence of Lawsonia intracellularis antibodies in intensive pig farms in China.

scientific article

Serpina1 is a potent inhibitor of IL-8-induced hematopoietic stem cell mobilization.

scholarly article

Short-term study of the uptake of PrP(Sc) by the Peyer's patches in hamsters after oral exposure to scrapie.

scientific article published on 10 February 2006

Spray Dried, Pasteurised Bovine Colostrum Protects Against Gut Dysfunction and Inflammation in Preterm Pigs

Staphylococcus aureus infected embolic stroke upregulates Orm1 and Cxcl2 in a rat model of septic stroke pathology

scientific article published on 01 February 2019

Structural gene variants in the porcine mannose-binding lectin 1 (MBL1) gene are associated with low serum MBL-A concentrations

scientific article published on 28 January 2011

The Effect of Inactivated Mycobacterium Paratuberculosis Vaccine on the Response to a Heterologous Bacterial Challenge in Pigs

scientific article published on 05 July 2019

The Impact of Staphylococcus Aureus Concentration on the Development of Pulmonary Lesions and Cytokine Expression After Intravenous Inoculation of Pigs

scientific article published on 28 March 2012

The acute phase response of haptoglobin and serum amyloid A (SAA) in cattle undergoing experimental infection with bovine respiratory syncytial virus.

scientific article published on November 2000

The effect of color type on early wound healing in farmed mink (Neovison vison)

scientific article

The negative acute phase response of serum transthyretin following Streptococcus suis infection in the pig

scientific article published on 01 July 2005

The porcine acute phase protein response to acute clinical and subclinical experimental infection with Streptococcus suis.

scientific article

The porcine acute phase response to infection with Actinobacillus pleuropneumoniae. Haptoglobin, C-reactive protein, major acute phase protein and serum amyloid A protein are sensitive indicators of infection.

scientific article

The potential for immunoglobulins and host defense peptides (HDPs) to reduce the use of antibiotics in animal production

scientific article published on 31 July 2018

The proteolytically stable peptidomimetic Pam-(Lys-βNSpe)6-NH2 selectively inhibits human neutrophil activation via formyl peptide receptor 2.

scientific article

The use of sequential organ failure assessment parameters in an awake porcine model of severe Staphylococcus aureus sepsis ⬇️

scientific article published on May 15, 2012

Toxoplasma gondii infection in the mountain hare (Lepus timidus) and domestic rabbit (Oryctolagus cuniculus). II. Early immune reactions

scientific article published in November 1997

Vaccination of pigs with attenuated Lawsonia intracellularis induced acute phase protein responses and primed cell-mediated immunity without reduction in bacterial shedding after challenge

scientific article published on 11 November 2014

Validation of putative reference genes for qRT-PCR normalization in tissues and blood from pigs infected with Actinobacillus pleuropneumoniae

article

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