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List of works by Daniele Dell'Orco

<i>SLC12A2</i>: a new gene associated with autosomal dominant Non-Syndromic hearing loss in humans

scientific article published in 2020

A Calcium-Relay Mechanism in Vertebrate Phototransduction ⬇️

scientific article (publication date: 19 June 2013)

A comprehensive model of the phototransduction cascade in mouse rod cells

scientific article published on 28 March 2014

A dynamic scaffolding mechanism for rhodopsin and transducin interaction in vertebrate vision ⬇️

scientific article published on 01 December 2011

A novel p.(Glu111Val) missense mutation in GUCA1A associated with cone-rod dystrophy leads to impaired calcium sensing and perturbed second messenger homeostasis in photoreceptors

scientific article published on 01 December 2018

A physiological role for the supramolecular organization of rhodopsin and transducin in rod photoreceptors ⬇️

scientific article published on May 16, 2013

Aldo-Keto Reductase 1C1 (AKR1C1) as the First Mutated Gene in a Family with Nonsyndromic Primary Lipedema

scientific article published on 29 August 2020

Allosteric communication pathways routed by Ca(2+)/Mg(2+) exchange in GCAP1 selectively switch target regulation modes

scientific article

Biochemical and biophysical characterization of a plant calmodulin: Role of the N- and C-lobes in calcium binding, conformational change, and target interaction

scientific article published on 17 December 2015

Biophysical characterization of antimicrobial peptides activity: from in vitro to ex vivo techniques

scientific article

CaF2 nanoparticles as surface carriers of GCAP1, a calcium sensor protein involved in retinal dystrophies.

scientific article published on 8 August 2017

Calcium binding, structural stability and guanylate cyclase activation in GCAP1 variants associated with human cone dystrophy

scientific article published in March 2010

Conformational changes in calcium-sensor proteins under molecular crowding conditions

Constitutive Activation of Guanylate Cyclase by the G86R GCAP1 Variant Is Due to "Locking" Cation-π Interactions that Impair the Activator-to-Inhibitor Structural Transition

scientific article published on 23 January 2020

Correlation between the molecular effects of mutations at the dimer interface of alanine-glyoxylate aminotransferase leading to primary hyperoxaluria type I and the cellular response to vitamin B6.

scientific article published on 6 November 2017

Dark and photoactivated rhodopsin share common binding modes to transducin

scientific article published on 26 February 2008

Delivery success rate of engineered nanoparticles in the presence of the protein corona: a systems-level screening ⬇️

scholarly article by Daniele Dell'Orco et al published November 2012 in Nanomedicine: Nanotechnology, Biology and Medicine

Detecting single photons: A supramolecular matter? ⬇️

scientific article published on November 23, 2012

Differential Nanosecond Protein Dynamics in Homologous Calcium Sensors

scientific article published on 07 August 2015

Divalent cations modulate membrane binding and pore formation of a potent antibiotic peptide analog of alamethicin

scientific article published on 20 December 2012

Dynamics of Conformational Ca2+-Switches in Signaling Networks Detected by a Planar Plasmonic Device

article

Dysfunction of cGMP signalling in photoreceptors by a macular dystrophy-related mutation in the calcium sensor GCAP1.

scientific article published on 26 December 2016

Effective delivery of recombinant proteins to rod photoreceptors via lipid nanovesicles

scientific article published on 25 April 2015

Effects of Membrane and Biological Target on the Structural and Allosteric Properties of Recoverin: A Computational Approach

scientific article published on 10 October 2019

Electrostatic contributions to the kinetics and thermodynamics of protein assembly

scientific article

Evolutionary-Conserved Allosteric Properties of Three Neuronal Calcium Sensor Proteins

scientific article published on 07 March 2019

Expanding the Clinical and Genetic Spectrum of <i>RAB28</i>-Related Cone-Rod Dystrophy: Pathogenicity of Novel Variants in Italian Families

scientific article published on 31 December 2020

Exploring the rate-limiting steps in visual phototransduction recovery by bottom-up kinetic modeling

scientific article published on 21 May 2013

Fast predictions of thermodynamics and kinetics of protein-protein recognition from structures: from molecular design to systems biology

scientific article published on 19 February 2009

Fingerprints of Calcium-Binding Protein Conformational Dynamics Monitored by Surface Plasmon Resonance

scientific article

Homodimerization of neurotensin 1 receptor involves helices 1, 2, and 4: insights from quaternary structure predictions and dimerization free energy estimations

scientific article

Impact of cone dystrophy-related mutations in GCAP1 on a kinetic model of phototransduction

scientific article published on 25 February 2014

In silico screening of mutational effects on enzyme-proteic inhibitor affinity: a docking-based approach

scientific article

In silico screening of mutational effects on transmembrane helix dimerization: insights from rigid-body docking and molecular dynamics simulations

scientific article published on 28 June 2007

Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function.

scientific article published on 2 August 2016

Involvement of the calcium sensor GCAP1 in hereditary cone dystrophies

scientific article published on June 2010

Involvement of the recoverin C-terminal segment in recognition of the target enzyme rhodopsin kinase

scientific article published in April 2011

Luminescent and paramagnetic properties of nanoparticles shed light on their interactions with proteins.

scientific article published on 21 February 2018

Mathematical modeling of the protein corona: implications for nanoparticulate delivery systems

scientific article published in May 2014

Mesoscopic Monte Carlo simulations of stochastic encounters between photoactivated rhodopsin and transducin in disc membranes

scientific article published on 18 March 2008

Modeling the time evolution of the nanoparticle-protein corona in a body fluid

scientific article

Modulation of Guanylate Cyclase Activating Protein 1 (GCAP1) Dimeric Assembly by Ca2+ or Mg2+: Hints to Understand Protein Activity

scientific article published on 05 October 2020

Molecular Recognition of Rhodopsin Kinase GRK1 and Recoverin Is Tuned by Switching Intra- and Intermolecular Electrostatic Interactions

scientific article published on 21 October 2019

Monomeric dark rhodopsin holds the molecular determinants for transducin recognition: insights from computational analysis

scientific article published on 06 February 2007

Nanodevice-induced conformational and functional changes in a prototypical calcium sensor protein

scientific article published on 8 November 2013

Network and atomistic simulations unveil the structural determinants of mutations linked to retinal diseases.

scientific article

Network-level analysis of light adaptation in rod cells under normal and altered conditions

scientific article published on 7 July 2009

Preferential Binding of Mg Over Ca to CIB2 Triggers an Allosteric Switch Impaired in Usher Syndrome Type 1J

scholarly article by Rosario Vallone published in January 2018

Probing fragment complementation by rigid-body docking: in silico reconstitution of calbindin D9k.

scientific article published in September 2005

Protein and Signaling Networks in Vertebrate Photoreceptor Cells

scientific article

Quantitative detection of conformational transitions in a calcium sensor protein by surface plasmon resonance

scientific article published on 10 September 2010

Quantitative structure-activity relationship analysis of canonical inhibitors of serine proteases

scientific article published on 23 January 2008

Quaternary structure predictions and estimation of mutational effects on the free energy of dimerization of the OMPLA protein

scientific article published on 23 May 2008

Regulatory function of the C-terminal segment of guanylate cyclase-activating protein 2.

scientific article

Rhodopsin activation follows precoupling with transducin: inferences from computational analysis

scientific article published on 01 November 2005

Rhodopsin transient complexes investigated by systems biology approaches

scientific article published in January 2015

S-Glutathionylation at Cys328 and Cys542 impairs STAT3 phosphorylation.

scientific article

Structural effects of Mg²⁺ on the regulatory states of three neuronal calcium sensors operating in vertebrate phototransduction.

scientific article

Structural plasticity of calmodulin on the surface of CaF2nanoparticles preserves its biological function

scientific article published on 13 October 2014

Systems biochemistry approaches to vertebrate phototransduction: towards a molecular understanding of disease ⬇️

scientific article published on October 1, 2010

The dimerization domain in outer segment guanylate cyclase is a Ca²⁺-sensitive control switch module

scientific article published on 17 July 2013

The interaction network of rhodopsin involving the heterotrimeric G-protein transducin and the monomeric GTPase Rac1 is determined by distinct binding processes

scientific article published on 13 October 2014

Transient complexes between dark rhodopsin and transducin: circumstantial evidence or physiological necessity?

scientific article published on February 2015

Two retinal dystrophy-associated missense mutations in GUCA1A with distinct molecular properties result in a similar aberrant regulation of the retinal guanylate cyclase

scientific article published on 10 September 2015

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