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List of works by Kelvin J. A. Davies

16S mitochondrial ribosomal RNA degradation is associated with apoptosis.

scientific article published on January 1997

A conserved role for the 20S proteasome and Nrf2 transcription factor in oxidative-stress adaptation in mammals, C. elegans and D. melanogaster ⬇️

scientific article published on October 4, 2012

A simple fluorescence labeling method for studies of protein oxidation, protein modification, and proteolysis.

scientific article published on 14 September 2011

Adaptive homeostasis

scientific article

Age-associated declines in mitochondrial biogenesis and protein quality control factors are minimized by exercise training

scientific journal article

Aging and SKN-1-dependent Loss of 20S Proteasome Adaptation to Oxidative Stress in C. elegans.

scientific article published on 23 June 2016

Aging-related decline in the induction of Nrf2-regulated antioxidant genes in human bronchial epithelial cells

scientific article published on 24 August 2017

Amyloid-β Toxicity and Tau Hyperphosphorylation are Linked Via RCAN1 in Alzheimer's Disease ⬇️

scientific article published on January 1, 2011

Are There Benefits to Mowing Wyoming Big Sagebrush Plant Communities? An Evaluation in Southeastern Oregon ⬇️

scientific article published on July 14, 2011

Biochemical adaptation of mitochondria, muscle, and whole-animal respiration to endurance training

scientific article published on 01 July 1981

Bone Mineral Density Discordance and Exploration of One of its Causes ⬇️

scientific article published on October 1, 2011

COVID-19 during Pregnancy and Postpartum

scientific article published on 08 November 2020

COVID-19 during Pregnancy and Postpartum: Antiviral Spectrum of Maternal Lactoferrin in Fetal and Neonatal Defense

scientific article published on 08 November 2020

Chronic expression of RCAN1-1L protein induces mitochondrial autophagy and metabolic shift from oxidative phosphorylation to glycolysis in neuronal cells.

scientific article published on 2 March 2012

Chronic overexpression of the calcineurin inhibitory gene DSCR1 (Adapt78) is associated with Alzheimer's disease

scientific article (publication date: 19 October 2001)

Cigarette smoke extract stimulates epithelial-mesenchymal transition through Src activation.

scientific article

Commentary on "Bach1 differentially regulates distinct Nrf2-dependent genes in human venous and coronary artery endothelial cells adapted to physiological oxygen levels" by Chapple et al.

scientific article published on 20 January 2016

Comparative cardiac oxygen radical metabolism by anthracycline antibiotics, mitoxantrone, bisantrene, 4'-(9-acridinylamino)-methanesulfon-m-anisidide, and neocarzinostatin

scientific article published on 01 October 1983

Comparative resistance of the 20S and 26S proteasome to oxidative stress.

scientific article published on November 1998

Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction.

scientific article published on 19 January 2013

Conservation of vitamin C by uric acid in blood

scientific article published on 01 January 1985

Corrigendum to "What is the concentration of hydrogen peroxide in blood and plasma?" [Arch. Biochem. Biophys. 603 (2016) 48-53].

scientific article published on 20 August 2016

Corrigendum to “Nrf2-regulated phase II enzymes are induced by chronic ambient nanoparticle exposure in young mice with age-related impairments”

scientific article published in December 2014

Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease.

scientific article published in December 2004

Degradation of damaged proteins: the main function of the 20S proteasome

scientific article published on January 2012

Degradation of oxidized proteins by the 20S proteasome.

scientific article

Degradation of oxidized proteins by the proteasome: Distinguishing between the 20S, 26S, and immunoproteasome proteolytic pathways.

scientific article published on 4 May 2016

Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome.

scientific article published on June 1996

Differential roles of proteasome and immunoproteasome regulators Pa28αβ, Pa28γ and Pa200 in the degradation of oxidized proteins.

scientific article published on 30 April 2012

Diminished stress resistance and defective adaptive homeostasis in age-related diseases.

scientific article published on 25 October 2017

Do RCAN1 proteins link chronic stress with neurodegeneration?

scientific article published on 16 June 2011

Down regulation of glutathione and glutamate cysteine ligase in the inflammatory response of macrophages

scientific article published on 16 July 2020

Down-regulation of mammalian mitochondrial RNAs during oxidative stress.

scientific article published on January 1997

Effects of dietary iron deficiency of iron-sulfur proteins and bioenergetic functions of skeletal muscle mitochondria

scientific article published on 01 February 1982

Even free radicals should follow some rules: a guide to free radical research terminology and methodology

scientific article

Evidence-based medicine: is the evidence out there for primary care clinicians? ⬇️

scientific article published on August 7, 2011

Exercise bioenergetics following sprint training

scientific article published on 01 April 1982

Formation and repair of oxidatively generated damage in cellular DNA.

scientific article published on 2 January 2017

Free radicals and exercise: an introduction.

scientific article published on 6 June 2007

Free radicals and tissue damage produced by exercise

scientific article published on 01 August 1982

Genetic aberrations in Chernobyl-related thyroid cancers: implications for possible future nuclear accidents or nuclear attacks.

scientific article published on December 2003

HSP70 and other possible heat shock or oxidative stress proteins are induced in skeletal muscle, heart, and liver during exercise.

scientific article published in January 1991

HSP70 mediates dissociation and reassociation of the 26S proteasome during adaptation to oxidative stress.

scientific article published on 24 June 2011

Hamster adapt78 mRNA is a Down syndrome critical region homologue that is inducible by oxidative stress.

scientific article published on June 1997

High school scientists

scientific article published on 01 April 1986

How do nutritional antioxidants really work: nucleophilic tone and para-hormesis versus free radical scavenging in vivo

scientific article published on 06 June 2013

Hydrogen peroxide induces the expression of adapt15, a novel RNA associated with polysomes in hamster HA-1 cells.

scientific article

Hydrogen peroxide production by red blood cells.

scientific article

Hydrogen peroxide-mediated ferrylhemoglobin generation in vitro and in red blood cells.

scientific article published in January 1994

Impairment of lon-induced protection against the accumulation of oxidized proteins in senescent wi-38 fibroblasts ⬇️

scientific article published on August 24, 2011

Importance of the lon protease in mitochondrial maintenance and the significance of declining lon in aging.

scientific article

Influence of DNA binding on the degradation of oxidized histones by the 20S proteasome.

scientific article

Macroxyproteinase (M.O.P.): a 670 kDa proteinase complex that degrades oxidatively denatured proteins in red blood cells.

scientific article published in January 1989

Manganese superoxide dismutase modulates interleukin-1alpha levels in HT-1080 fibrosarcoma cells.

scientific article published on August 1996

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

scientific article

Mechanism of the formation and proteolytic release of H2O2-induced dityrosine and tyrosine oxidation products in hemoglobin and red blood cells.

scientific article published on 9 April 2001

Mitochondrial Lon protease in human disease and aging: Including an etiologic classification of Lon-related diseases and disorders

scientific article

Mitochondrial NADH dehydrogenase-catalyzed oxygen radical production by adriamycin, and the relative inactivity of 5-iminodaunorubicin

scientific article published on 01 March 1983

Mitochondrial biogenesis-associated factors underlie the magnitude of response to aerobic endurance training in rats

scientific journal article

Modulation of Lon protease activity and aconitase turnover during aging and oxidative stress.

scientific article published in December 2002

Modulation of a cardiogenic shock inducible RNA by chemical stress: adapt73/PigHep3

scientific article published on 01 May 1997

Multiple roles of the DSCR1 (Adapt78 or RCAN1) gene and its protein product calcipressin 1 (or RCAN1) in disease

scientific article

Nrf2-dependent induction of proteasome and Pa28αβ regulator are required for adaptation to oxidative stress

scientific article published on 3 February 2012

Nrf2-regulated phase II enzymes are induced by chronic ambient nanoparticle exposure in young mice with age-related impairments.

scientific article published on 6 March 2012

Optimal determination of heart tissue 26S-proteasome activity requires maximal stimulating ATP concentrations.

scientific article published on 30 November 2006

Oxidant-inducible adapt 15 RNA is associated with growth arrest- and DNA damage-inducible gadd153 and gadd45

scientific article published on 01 May 1996

Oxidative DNA damage & repair: An introduction.

scientific article published on 28 March 2017

Oxidative and calcium stress regulate DSCR1 (Adapt78/MCIP1) protein.

scientific article published in September 2003

Oxidative and non-oxidative mechanisms in the inactivation of cardiac mitochondrial electron transport chain components by doxorubicin.

scientific article published on April 1989

Oxidative stress causes a general, calcium-dependent degradation of mitochondrial polynucleotides

scientific article published on 01 December 1998

Oxidative stress response and Nrf2 signaling in aging

scientific article

Oxidized and ubiquitinated proteins may predict recovery of postischemic cardiac function: essential role of the proteasome.

scientific article published in May 2005

Plant community diversity and native plant abundance decline with increasing abundance of an exotic annual grass ⬇️

scientific article published on April 21, 2011

Poly-ADP ribose polymerase activates nuclear proteasome to degrade oxidatively damaged histones

scientific article published on May 1999

Polynucleotide degradation during early stage response to oxidative stress is specific to mitochondria

scientific article published on 01 January 2000

Potential roles of protein oxidation and the immunoproteasome in MHC class I antigen presentation: the 'PrOxI' hypothesis.

scientific article published on March 2004

Progress in therapy for Duchenne muscular dystrophy ⬇️

scientific article published on July 31, 2011

Proteasome inhibitors induce intracellular protein aggregation and cell death by an oxygen-dependent mechanism.

scientific article published in May 2003

Proteasome-dependent turnover of protein disulfide isomerase in oxidatively stressed cells.

scientific article published in January 2002

Protein degradation as an index of oxidative stress

scientific article published on 01 January 1990

Protein degradation in mitochondria: implications for oxidative stress, aging and disease: a novel etiological classification of mitochondrial proteolytic disorders.

scientific article

Protein modification by oxidants and the role of proteolytic enzymes.

scientific article

Protein oxidation and 20S proteasome-dependent proteolysis in mammalian cells ⬇️

scientific article published on September 1, 2001

Protein oxidation and degradation during postmitotic senescence.

scientific article published on November 2005

Protein oxidative modifications in the ageing brain: Consequence for the onset of neurodegenerative disease ⬇️

scientific article published on 06 September 2010

Protein turnover by the proteasome in aging and disease.

scientific article

Proteolysis in cultured liver epithelial cells during oxidative stress. Role of the multicatalytic proteinase complex, proteasome.

scientific article published on February 1995

RCAN1 (DSCR1 or Adapt78) stimulates expression of GSK-3beta.

scientific article published on May 2006

RasGrf1 and Aging ⬇️

scientific article published on May 1, 2011

Reactive oxygen and nitrogen species in neurodegeneration

scientific article published in September 2013

Redox Regulation of Homeostasis and Proteostasis in Peroxisomes.

scientific article

Regulator of calcineurin (RCAN1-1L) is deficient in Huntington disease and protective against mutant huntingtin toxicity in vitro

scientific article published on 06 March 2009

Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin.

scientific article published on 26 June 2007

Resveratrol attenuates exercise-induced adaptive responses in rats selectively bred for low running performance.

scientific article published on 04 June 2013

Resveratrol enhances exercise training responses in rats selectively bred for high running performance ⬇️

scientific article published on February 17, 2013

Reversal of diabetic vasculopathy in a rat model of type 1 diabetes by opiorphin-related peptides ⬇️

scientific article published on July 22, 2011

SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle.

scientific article

Selective degradation of oxidatively modified protein substrates by the proteasome.

scientific article

Sex-specific adaptive homeostasis in D. melanogaster depends on increased proteolysis by the 20S Proteasome: Data-in-Brief.

scientific article

Sexual dimorphism in oxidant-induced adaptive homeostasis in multiple wild-type D. melanogaster strains

scientific article

TGFβ1 rapidly activates Src through a non-canonical redox signaling mechanism.

scientific article

Tau protein degradation is catalyzed by the ATP/ubiquitin-independent 20S proteasome under normal cell conditions.

scientific article

The DAN1 gene of S. cerevisiae is regulated in parallel with the hypoxic genes, but by a different mechanism.

scientific article published in June 1997

The DSCR1 (Adapt78) isoform 1 protein calcipressin 1 inhibits calcineurin and protects against acute calcium-mediated stress damage, including transient oxidative stress.

scientific article

The Immunoproteasome in oxidative stress, aging, and disease.

scientific article published on 20 April 2016

The Mitochondrial Lon Protease Is Required for Age-Specific and Sex-Specific Adaptation to Oxidative Stress.

scientific article published on 23 November 2016

The Oxygen Paradox, oxidative stress, and ageing

scientific article

The Proteasome and Oxidative Stress in Alzheimer's Disease

scientific article published on 8 July 2016

The age- and sex-specific decline of the 20s proteasome and the Nrf2/CncC signal transduction pathway in adaption and resistance to oxidative stress in Drosophila melanogaster

scientific article

The calcineurin antagonist RCAN1-4 is induced by exhaustive exercise in rat skeletal muscle

scientific article published on 26 June 2015

The essential role of calcium in induction of the DSCR1 (ADAPT78) gene.

scientific article

The evolution of Free Radical Biology & Medicine: a 20-year history.

scientific article published on 23 September 2005

The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes.

scientific article published on December 2010

The inhibition of bacterial growth by hypochlorous acid. Possible role in the bactericidal activity of phagocytes

scientific article

The molecular chaperone Hsp70 promotes the proteolytic removal of oxidatively damaged proteins by the proteasome.

scientific article published on 03 August 2016

The peroxisomal Lon protease LonP2 in aging and disease: functions and comparisons with mitochondrial Lon protease LonP1

scientific article published on 08 February 2016

The proteasomal system and HNE-modified proteins.

scientific article

The role of declining adaptive homeostasis in ageing

scientific article published on 13 October 2017

Transient adaptation of oxidative stress in mammalian cells.

scientific article published on April 1995

Transit of H2O2 across the endoplasmic reticulum membrane is not sluggish

scientific article

Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome.

scientific article

Ubisemiquinone radicals in liver: implications for a mitochondrial Q cycle in vivo

scientific article published on 01 August 1982

Upregulation of the mitochondrial Lon Protease allows adaptation to acute oxidative stress but dysregulation is associated with chronic stress, disease, and aging.

scientific article

Uric acid-iron ion complexes. A new aspect of the antioxidant functions of uric acid.

scientific article published on May 1986

Vitamin E deficiency and photosensitization of electron-transport carriers in microsomes

scientific article published on 01 March 1982

What is the concentration of hydrogen peroxide in blood and plasma?

scientific article published on 9 May 2016

adapt33, a novel oxidant-inducible RNA from hamster HA-1 cells.

scientific article

adapt78, a stress-inducible mRNA, is related to the glucose-regulated protein family of genes.

scientific article published on August 1999

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