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List of works by Stéphane Hatem

A calcium-sensitive promoter construct for gene therapy ⬇️

scientific article published on March 29, 2012

A glimpse at cardiac ion channel macromolecular complexes

scientific article published on 22 April 2014

A new method of ultrasonic nonviral gene delivery to the adult myocardium

scientific article

A roadmap to improve the quality of atrial fibrillation management: proceedings from the fifth Atrial Fibrillation Network/European Heart Rhythm Association consensus conference

scientific article

A truncating SCN5A mutation combined with genetic variability causes sick sinus syndrome and early atrial fibrillation.

scientific article

Abnormal sodium current properties contribute to cardiac electrical and contractile dysfunction in a mouse model of myotonic dystrophy type 1.

scientific article published on 10 December 2014

Adult cardiac myocytes survive and remain excitable during long-term culture on synthetic supports

article

Assessment of left atrial function by MRI myocardial feature tracking

scientific article published on 28 January 2015

Atrial Fibrillation and Obesity

scientific article published on 01 July 2015

Atrial fibrillation and rapid acute pacing regulate adipocyte/adipositas-related gene expression in the atria.

scientific article published on 23 March 2015

Behaviour of human atrial myocytes in culture is donor age dependent

article

Brugada syndrome and abnormal splicing of SCN5A in myotonic dystrophy type 1.

scientific article

Cardiac adipose tissue and atrial fibrillation: the perils of adiposity

scientific article

Cardiac-specific ablation of synapse-associated protein SAP97 in mice decreases potassium currents but not sodium current

scientific journal article

Cardiovascular Disease: Calcium Channel Anomalies

scholarly article published 2014

Cholesterol Regulation of Cardiac Ion Channels

Cholesterol and cardiac arrhythmias.

scientific article published on July 2010

Cholesterol modulates the recruitment of Kv1.5 channels from Rab11-associated recycling endosome in native atrial myocytes

scholarly article

Chronic hemodynamic overload of the atria is an important factor for gap junction remodeling in human and rat hearts

scientific article published on 16 June 2006

Corrigendum to “Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice” Int J Cardiol 166 (2013), 366–74

scholarly article published in International Journal of Cardiology

Dedifferentiation of atrial myocytes during atrial fibrillation: role of fibroblast proliferation in vitro.

scientific article

Different isoforms of synapse-associated protein, SAP97, are expressed in the heart and have distinct effects on the voltage-gated K+ channel Kv1.5

scientific article

Differential effects of quinidine and flecainide on plateau duration of human atrial action potential

scientific article published on 01 November 1992

Does the loss of transverse tubules contribute to dyssynchronous Ca2+ release during heart failure?

scientific article published on 01 April 2004

Dominant-negative effect of SCN5A N-terminal mutations through the interaction of Na(v)1.5 α-subunits

scientific article published on 27 June 2012

Downregulation of the calcium current in human right atrial myocytes from patients in sinus rhythm but with a high risk of atrial fibrillation.

scientific article published on 7 April 2008

Doxorubicin induces slow ceramide accumulation and late apoptosis in cultured adult rat ventricular myocytes

scientific article

Dynamic of ion channel expression at the plasma membrane of cardiomyocytes

scientific article published on July 2012

Epicardial adipose tissue and atrial fibrillation

scientific article published on 18 March 2014

Expert consensus document: Defining the major health modifiers causing atrial fibrillation: a roadmap to underpin personalized prevention and treatment.

scientific article published on 24 December 2015

Expression, regulation and role of the MAGUK protein SAP-97 in human atrial myocardium.

scientific article

F 16915 prevents heart failure-induced atrial fibrillation: a promising new drug as upstream therapy

article

Fibrosis of the left atria during progression of heart failure is associated with increased matrix metalloproteinases in the rat

scientific article published on 01 July 2003

Human epicardial adipose tissue has a specific transcriptomic signature depending on its anatomical peri-atrial, peri-ventricular, or peri-coronary location

scientific article

Human epicardial adipose tissue induces fibrosis of the atrial myocardium through the secretion of adipo-fibrokines

scientific article published on 22 March 2013

Integrating new approaches to atrial fibrillation management: the 6th AFNET/EHRA Consensus Conference

scientific article published on 2 January 2018

Is epicardial adipose tissue an epiphenomenon or a new player in the pathophysiology of atrial fibrillation?

scientific article published on 01 June 2014

Lateral Membrane-Specific MAGUK CASK Down-Regulates NaV1.5 Channel in Cardiac Myocytes.

scientific article published on 30 June 2016

Le cisaillement régule le trafic des canaux potassiques atriaux

scientific article published on 31 March 2014

Left atrial aging: a cardiac magnetic resonance feature-tracking study

scientific article published on 8 January 2016

Left atrium wall tracking from MR images for strain assessment

scientific article published in January 2014

Long-term outcomes of pandemic 2009 influenza A(H1N1)-associated severe ARDS.

scientific article

MOG1: a new susceptibility gene for Brugada syndrome

scientific article published on 29 March 2011

Macromolecular Complexes and Cardiac Potassium Channels

scholarly article published 2014

Maximal exercise limitation in functionally overreached triathletes: role of cardiac adrenergic stimulation

scientific article published on 12 June 2014

Membrane cholesterol modulates Kv1.5 potassium channel distribution and function in rat cardiomyocytes

scientific article

Mesenchymal stem cell delivery into rat infarcted myocardium using a porous polysaccharide-based scaffold: a quantitative comparison with endocardial injection

scientific article published on 21 September 2011

Moderate and chronic hemodynamic overload of sheep atria induces reversible cellular electrophysiologic abnormalities and atrial vulnerability

scientific article published in November 2004

Multidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferation

scientific article

Mutation of delta-sarcoglycan is associated with Ca(2+) -dependent vascular remodeling in the Syrian hamster

scientific article published in July 2007

Myocardial cell death in fibrillating and dilated human right atria.

scientific article published in November 1999

Mécanismes moléculaires et cellulaires de la fibrillation auriculaire : existe-t-il de nouvelles stratégies thérapeutiques ? ⬇️

scientific article published on 03 April 2012

Novel mechanisms in the pathogenesis of atrial fibrillation: practical applications.

scientific article

Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice

scientific article published on 16 November 2011

Peroxisome proliferator-activated receptor beta stimulation induces rapid cardiac growth and angiogenesis via direct activation of calcineurin

scientific article

Personalized management of atrial fibrillation: Proceedings from the fourth Atrial Fibrillation competence NETwork/European Heart Rhythm Association consensus conference

scientific article

Primary Culture of Human Atrial Myocytes is Associated with the Appearance of Structural and Functional Characteristics of Immature Myocardium

article

Protease-Activated Receptor-1 Antagonist F 16618 Reduces Arterial Restenosis by Down-Regulation of Tumor Necrosis Factor and Matrix Metalloproteinase 7 Expression, Migration, and Proliferation of Vascular Smooth Muscle Cells

scientific article published on 07 December 2010

Protease-activated receptor-1 mediates thrombin-induced persistent sodium current in human cardiomyocytes

scientific article published on 6 March 2008

Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes

scientific article published on 16 November 2011

SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes

scientific article

SERCA2a controls the mode of agonist-induced intracellular Ca2+ signal, transcription factor NFAT and proliferation in human vascular smooth muscle cells

scientific article published on 29 December 2010

Shear stress triggers insertion of voltage-gated potassium channels from intracellular compartments in atrial myocytes

scientific article

Somatotopic organization of the analgesic effects of motor cortex rTMS in neuropathic pain.

scientific article published on December 2006

Species differences in the activity of the Na(+)-Ca2+ exchanger in mammalian cardiac myocytes

article

Specificities of atrial electrophysiology: Clues to a better understanding of cardiac function and the mechanisms of arrhythmias

scientific article published on 08 September 2009

Spironolactone reduces fibrosis of dilated atria during heart failure in rats with myocardial infarction

scientific article

Statin, the black box.

scientific article published in June 2008

The European Network for Translational Research in Atrial Fibrillation (EUTRAF): objectives and initial results

scientific article published on 12 September 2015

The anchoring protein SAP97 retains Kv1.5 channels in the plasma membrane of cardiac myocytes

scientific article

The antiarrhythmic agent bertosamil induces inactivation of the sustained outward K+ current in human atrial myocytes.

scientific article

Voluntary Physical Activity Protects from Susceptibility to Skeletal Muscle Contraction–Induced Injury But Worsens Heart Function in mdx Mice

scientific article published on 04 March 2013

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