List of works by William R. Markesbery

"Preclinical" AD revisited: neuropathology of cognitively normal older adults.

scientific article published in August 2000

31P magnetic resonance spectroscopy in Alzheimer's and Pick's disease

scientific article published in January 1993

31P spectroscopy in experimental embolic stroke: correlation with infarct size

scientific article

3alpha,5alpha-THP: a potential plasma neurosteroid biomarker in Alzheimer's disease and perhaps non-Alzheimer's dementia

scientific article published on 18 October 2005

4-Hydroxy-2-Nonenal Pyrrole Adducts in Human Neurodegenerative Disease ⬇️

scientific article published on August 1, 1997

4-Hydroxynonenal oxidatively modifies histones: implications for Alzheimer's disease

scientific article published in February 2004

4-Hydroxynonenal, a product of lipid peroxidation, damages cholinergic neurons and impairs visuospatial memory in rats

scientific article published on March 1998

4-hydroxynonenal increases neuronal susceptibility to oxidative stress

scientific article published on 01 December 1999

A randomized trial of surgery in the treatment of single metastases to the brain

scientific article

A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide

scientific article published in January 1997

A search for longitudinal variations in trace element levels in nails of Alzheimer's disease patients

scientific article published on 01 July 1990

AD brain pathology: vascular origins? Results from the HAAS autopsy study

scientific article

AD lesions and infarcts in demented and non-demented Japanese-American men.

scientific article published in January 2005

APOε2 and education in cognitively normal older subjects with high levels of AD pathology at autopsy: findings from the Nun Study

scientific article

Abeta solubility and deposition during AD progression and in APPxPS-1 knock-in mice

scientific article

Accuracy of clinical criteria for AD in the Honolulu-Asia Aging Study, a population-based study.

scientific article published in July 2001

Acetylcholinesterase inhibitor treatment is associated with relatively slow cognitive decline in patients with Alzheimer's disease and AD + DLB

scientific article published on January 2009

Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures

scientific article

Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures

scientific article published on 01 October 2000

Age and gender effects on human brain anatomy: a voxel-based morphometric study in healthy elderly

scientific article published on 13 June 2006

Age group differences in positive and negative affect among oldest-old adults: findings from the Georgia Centenarian Study

scientific article

Age-associated alteration of serotonergic synaptic neurochemistry in rat rostral hypothalamus

scientific article published in January 1985

Age-related loss of phospholipid asymmetry in APP(NLh)/APP(NLh) x PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice: relevance to Alzheimer disease

scientific article

Aging in a dish: age-dependent changes of neuronal survival, protein oxidation, and creatine kinase BB expression in long-term hippocampal cell culture

scientific article

Alterations in zinc transporter protein-1 (ZnT-1) in the brain of subjects with mild cognitive impairment, early, and late-stage Alzheimer's disease

scientific article

Alterations of zinc transporter proteins ZnT-1, ZnT-4 and ZnT-6 in preclinical Alzheimer's disease brain

scientific article

Altered 8-oxoguanine glycosylase in mild cognitive impairment and late-stage Alzheimer's disease brain

scientific article published on 11 June 2008

Altered expression of zinc transporters-4 and -6 in mild cognitive impairment, early and late Alzheimer's disease brain

scientific article

Altered serotonergic and cholinergic synaptic markers in Pick's disease

scientific article published in August 1991

Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study

scientific journal article

Alzheimer neuropathologic alterations in aged cognitively normal subjects

scientific article published in April 1999

Alzheimer's disease and head circumference

scientific article

Alzheimer's disease, dental amalgam and mercury

scientific article published in February 1999

Alzheimer's disease. Aminergic-cholinergic alterations in hypothalamus.

scientific article published in September 1988

Alzheimer's disease: monoamines and spiperone binding reduced in nucleus basalis

scientific article published in June 1986

Alzheimer's disease: no alteration in the physical state of erythrocyte membrane glycoconjugates.

scientific article published in July 1985

Alzheimer's-type neuropathology in the precuneus is not increased relative to other areas of neocortex across a range of cognitive impairment

scientific article

Amyloid beta-peptide (1-40)-mediated oxidative stress in cultured hippocampal neurons. Protein carbonyl formation, CK BB expression, and the level of Cu, Zn, and Mn SOD mRNA.

scientific article published in June 1998

Amyloid beta-peptide effects on synaptosomes from apolipoprotein E-deficient mice.

scientific article published on April 2000

An aberrant protein complex in CSF as a biomarker of Alzheimer disease.

scientific article published on 30 April 2008

An automated technique for measuring hippocampal volumes from MR imaging studies.

scientific article

Apolipoprotein E allelic influence on human cerebrospinal fluid apolipoproteins.

scientific article published in December 1998

Applications of neutron activation analysis to the study of age-related neurological diseases

scientific article published in August 1987

Association between male gender and cortical Lewy body pathology in large autopsy series

scientific article

Association of HFE mutations with neurodegeneration and oxidative stress in Alzheimer's disease and correlation with APOE ⬇️

scientific article published on May 15, 2003

Association of olfactory dysfunction with incidental Lewy bodies

scientific article published in December 2006

Associations of cortical astrogliosis with cognitive performance and dementia status ⬇️

journal article published in 2004

Autoantibodies to amyloid beta-peptide (Abeta) are increased in Alzheimer's disease patients and Abeta antibodies can enhance Abeta neurotoxicity: implications for disease pathogenesis and vaccine development

scientific article published on January 2003

Beta-amyloid mediated nitration of manganese superoxide dismutase: implication for oxidative stress in a APPNLH/NLH X PS-1P264L/P264L double knock-in mouse model of Alzheimer's disease.

scientific article

Biophysical and biochemical characterization of the intrinsic fluorescence from neurofibrillary tangles

scientific article published on 8 June 2005

Brain biopsy in cases of neonatal herpes simplex encephalitis

scientific article

Brain donation in normal aging: procedures, motivations, and donor characteristics from the Biologically Resilient Adults in Neurological Studies (BRAiNS) Project

scientific article published in December 2001

Brain infarction and the clinical expression of Alzheimer disease. The Nun Study

scientific article published on March 1997

Brain manganese concentrations in human aging and Alzheimer's disease.

scientific article published in January 1984

Brain regional quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease

scientific article

Brain structural alterations before mild cognitive impairment

scientific article published in April 2007

Brain trace element concentrations in aging

scientific article published on 01 January 1984

Brain trace elements in Alzheimer's disease

scientific article published in January 1986

Brain trace elements in Pick's disease

scientific article published on January 1984

Brains with medial temporal lobe neurofibrillary tangles but no neuritic amyloid plaques are a diagnostic dilemma but may have pathogenetic aspects distinct from Alzheimer disease.

scientific article published in July 2009

CADASIL in a North American family

scientific article published in April 1999

CD36 overexpression in human brain correlates with beta-amyloid deposition but not with Alzheimer's disease

scientific article published in April 2004

Carboxy terminal of beta-amyloid deposits in aged human, canine, and polar bear brains

scientific article published in March 1996

Cerebrospinal fluid F2-isoprostane levels are increased in Alzheimer's disease

scientific article published in September 1998

Cerebrospinal fluid lipoprotein delivery to human neuronal cells is increased in Alzheimer's disease and is dependent on apoE monomer concentration

scientific article

Cerebrospinal fluid lipoproteins are more vulnerable to oxidation in Alzheimer's disease and are neurotoxic when oxidized ex vivo

scientific article

Cerebrovascular pathology and dementia in autopsied Honolulu-Asia Aging Study participants

scientific article

Changes in thiol content and expression of glutathione redox system genes in the hippocampus and cerebellum in Alzheimer's disease

scientific article published in April 2001

Characterization of Japanese-American men with a single neocortical AD lesion type

scientific article published on 17 May 2007

Clinical features of mild cognitive impairment differ in the research and tertiary clinic settings

scientific article published on 23 August 2008

Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles "do count" when staging disease severity

scientific article

Cognitive performance in centenarians and the oldest old: norms from the Georgia Centenarian Study

scientific article

Comparison of neuropathologic criteria for the diagnosis of Alzheimer's disease

scientific article published in July 1997

Comparison of recruitment efforts targeted at primary care physicians versus the community at large for participation in Alzheimer disease clinical trials

scientific article

Comparison of the effects of elevated intracellular aluminum and calcium levels on neuronal survival and tau immunoreactivity

scientific article published in January 1993

Congenital myopathy and cardiomyopathy with identical ultrastructural changes

scientific article published in October 1990

Copper, iron and zinc in Alzheimer's disease senile plaques

scientific article published in June 1998

Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: possible relation to oxidative stress

scientific article

Correlates of functional capacity among centenarians.

scientific article published on 19 September 2011

Cortical biopsy in Alzheimer's disease: diagnostic accuracy and neurochemical, neuropathological, and cognitive correlations. Intraventricular Bethanecol Study Group

scientific article published on November 1, 1992

Cortical senile plaques in coronary artery disease, aging and Alzheimer's disease ⬇️

scientific article published on November 1, 1990

Critical decline in fine motor hand movements in human aging

scientific article published on 01 October 1999

Cyclic nucleotides attenuate lipid peroxidation-mediated neuron toxicity

scientific article published on 01 November 1998

DNA oxidation in Alzheimer's disease

scientific article published on November 2006

Damage to lipids, proteins, DNA, and RNA in mild cognitive impairment

scientific article published on July 2007

Decrease in peptide methionine sulfoxide reductase in Alzheimer's disease brain

scientific article

Decreased RNA, and increased RNA oxidation, in ribosomes from early Alzheimer's disease.

scientific article

Decreased base excision repair and increased helicase activity in Alzheimer's disease brain.

scientific article published in February 2000

Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer's disease

scientific article published in December 1998

Decreased levels of proteasome activity and proteasome expression in aging spinal cord

scientific article

Decreased thioredoxin and increased thioredoxin reductase levels in Alzheimer's disease brain.

scientific article published in February 2000

Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment

scientific article

Delayed recall, hippocampal volume and Alzheimer neuropathology: findings from the Nun Study.

scientific article published in February 2004

Depression among centenarians and the oldest old: contributions of cognition and personality

scientific article

Designing a large prevention trial: statistical issues.

scientific article published in January 2004

Distal and proximal resource influences on economic dependency among the oldest old.

scientific article

Distribution of reducible 4-hydroxynonenal adduct immunoreactivity in Alzheimer disease is associated with APOE genotype

scientific article published on May 1998

Ectopic expression of Musashi-1 in Alzheimer disease and Pick disease

scientific article

Effects of short-term Western diet on cerebral oxidative stress and diabetes related factors in APP x PS1 knock-in mice.

scientific article

Electron spin resonance study of membrane protein alterations in erythrocytes in Huntington's disease ⬇️

scientific article published on June 2, 1977

Electron spin resonance, hematological, and deformability studies of erythrocytes from patients with Huntington's disease ⬇️

scientific article published on March 8, 1979

Elemental imbalances in the olfactory pathway in Alzheimer's disease

scientific article

Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression ⬇️

scientific article published on October 20, 2010

Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease

scientific article published in September 1997

Elevated CSF prostaglandin E2 levels in patients with probable AD

scientific article published on 01 October 1999

Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene

scientific article published on 22 December 2004

Elevated levels of 3-nitrotyrosine in brain from subjects with amnestic mild cognitive impairment: implications for the role of nitration in the progression of Alzheimer's disease.

scientific article published on 7 March 2007

Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease ⬇️

scientific article published on August 1, 1995

Elevated zinc transporter-6 in mild cognitive impairment, Alzheimer disease, and pick disease

scientific article published in May 2006

Elevation of AKR7A2 (succinic semialdehyde reductase) in neurodegenerative disease

scientific article

Evidence for a membrane surface defect in erythrocytes in Huntington's disease ⬇️

scientific article published on August 18, 1980

Evidence for an Altered Physical State of Membrane Proteins in Erythrocytes in Friedreich's Ataxia ⬇️

scientific article published on May 1, 1979

Evidence for an increased rate of choline efflux across erythrocyte membranes in Alzheimer's disease.

scientific article published in July 1985

Evidence of increased oxidative damage in subjects with mild cognitive impairment.

scientific article

Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease.

scientific article

Expression and activities of aldo-keto oxidoreductases in Alzheimer disease

scientific article (publication date: July 2001)

Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain

scientific article

Expression of glutathione-S-transferase isozyme in the SY5Y neuroblastoma cell line increases resistance to oxidative stress

scientific article

Expression of microsomal epoxide hydrolase is elevated in Alzheimer's hippocampus and induced by exogenous beta-amyloid and trimethyl-tin.

scientific article

F2-isoprostanes in Alzheimer and other neurodegenerative diseases

scientific article

Familial influence on plaque formation in the beagle brain

scientific article published in December 1992

Familial progressive subcortical gliosis.

scientific article published in September 1994

Familial progressive subcortical gliosis: presence of prions and linkage to chromosome 17

scientific article published on 01 June 1995

Family history and adaptation among centenarians and octogenarians

scientific article

Formation of isoprostane-like compounds (neuroprostanes) in vivo from docosahexaenoic acid

scientific article published in May 1998

Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease

scientific article published in January 1998

Free radical-mediated damage to brain in Alzheimer's disease and its transgenic mouse models

scientific article published on 24 April 2008

General immunocompetence of rats bearing avian sarcoma virus-induced intracranial tumors ⬇️

scientific article published on January 1, 1978

Genetic and expression profiles of cerebellar liponeurocytomas.

scientific article published in July 2004

Glutathione transferase protects neuronal cultures against four hydroxynonenal toxicity

scientific article published in November 1998

Hippocampal volume as an index of Alzheimer neuropathology: findings from the Nun Study

scientific article published in May 2002

Human cerebral neuropathology of Type 2 diabetes mellitus

scientific article

Huntington's disease: A generalized membrane defect ⬇️

scientific article published on March 9, 1981

Identification and characterization of OGG1 mutations in patients with Alzheimer's disease

scientific article published on 10 April 2007

Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach

scientific article published on 27 December 2005

Imaging the centenarian brain. A computed tomographic study

scientific article published in September 1985

Imbalances of trace elements related to oxidative damage in Alzheimer's disease brain.

scientific article published in June 1998

Impaired proteasome function in Alzheimer's disease

scientific article published on 01 July 2000

Improved predictive model for pre-symptomatic mild cognitive impairment and Alzheimer's disease

scientific article published on 3 September 2008

Increased 5S rRNA oxidation in Alzheimer's disease

scientific article

Increased DNA oxidation and decreased levels of repair products in Alzheimer's disease ventricular CSF.

scientific article

Increased chloride transport in erythrocytes in Huntington's disease

scientific article

Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease

scientific article

Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease

scientific article published in July 2005

Increased nuclear DNA oxidation in the brain in Alzheimer's disease

scientific article published in November 1998

Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease

scientific article published in May 2005

Increased oxidative damage in nuclear and mitochondrial DNA in mild cognitive impairment

scientific article published on 9 January 2006

Increased protein hydrophobicity in response to aging and Alzheimer disease

scientific article

Increased sodium plus potassium adenosine triphosphatase activity in erythrocyte membranes in Huntington's disease ⬇️

scientific article published on July 1, 1978

Induction of hyperphosphorylated tau in primary rat cortical neuron cultures mediated by oxidative stress and glycogen synthase kinase-3.

scientific article published in December 2004

Invasiveness in primary intracranial tumors: Part 1. An experimental model using cloned SV40 virus-produced hamster brain tumors

scientific article

Iodine-123 HIPDM brain imaging findings in subacute spongiform encephalopathy (Creutzfeldt-Jakob disease).

scientific article published on September 1987

Iron, selenium and glutathione peroxidase activity are elevated in sporadic motor neuron disease

scientific article published on 01 November 1994

Isolation of neural precursor cells from Alzheimer's disease and aged control postmortem brain

scientific article published on 23 June 2005

Juvenile amaurotic idiocy (neuronal ceroid lipofuscinosis) and lymphocyte fingerprint profiles ⬇️

scientific article published on December 1, 1978

Laminar organization of cholinergic circuits in human frontal cortex in Alzheimer's disease and aging

scientific article published in October 1985

Laser microprobe analysis of brain aluminum in Alzheimer's disease

scientific article published on January 1993

Laser microprobe mass spectrometric study of aluminum and silicon in brain emboli related to cardiac surgery

scientific article

Late-onset sporadic progressive subcortical gliosis

scientific article published in May 1998

Lewy body pathology in normal elderly subjects

scientific article published on July 2009

Linguistic ability in early life and cognitive function and Alzheimer's disease in late life. Findings from the Nun Study

scientific article

Linguistic ability in early life and the neuropathology of Alzheimer's disease and cerebrovascular disease. Findings from the Nun Study.

scientific article published in April 2000

Lipid peroxidation in aging brain and Alzheimer's disease

scientific article

Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment

scientific article published in November 2005

Low sensitivity in clinical diagnoses of dementia with Lewy bodies

scientific article

Lymphocyte subpopulations and responsiveness in rats bearing intracranial tumors induced by avian sarcoma virus

scientific article

MRI temporal lobe volume measures and neuropsychologic function in Alzheimer's disease

scientific article

Memory complaints in nondemented men predict future pathologic diagnosis of Alzheimer disease.

scientific article published on November 2004

Methodological Considerations in Studying Centenarians: Lessons Learned From the Georgia Centenarian Studies.

scientific article

Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons

scientific article

Molecular changes in brain aging and Alzheimer's disease are mirrored in experimentally silenced cortical neuron networks

scientific article

Monoaminergic and cholinergic synaptic markers in the nucleus basalis of Meynert (nbM): normal age-related changes and the effect of heart disease and Alzheimer's disease

scientific article published in June 1992

Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implication

scientific journal article

N-terminal heterogeneity of parenchymal and cerebrovascular Abeta deposits

scientific article published in January 1998

NOX activity is increased in mild cognitive impairment

scientific article

Neprylisin decreases uniformly in Alzheimer's disease and in normal aging

scientific article

Neuroanatomic and neurotransmitter influences on immune function

scientific article published in August 1985

Neuroimmunomodulation: neural anatomical basis for impairment and facilitation

scientific article published on 01 July 1982

Neuron Specific Toxicity of Oligomeric Amyloid-β: Role for JUN-Kinase and Oxidative Stress ⬇️

scientific article published on January 1, 2010

Neuronal RNA in Pick's and Alzheimer's diseases. Comparison of disease-susceptible and disease-resistant cortical areas.

scientific article published in February 1989

Neuronal RNA in relation to Alz-50 immunoreactivity in Alzheimer's disease

scientific article

Neuronal RNA in relation to neuronal loss and neurofibrillary pathology in the hippocampus in Alzheimer's disease

scientific article published in January 1987

Neuropathologic substrate of mild cognitive impairment.

scientific article published in January 2006

Neuropathological criteria for the diagnosis of Alzheimer's disease

scientific article published on July 1997

Neuropathology and cognitive impairment in Alzheimer disease: a complex but coherent relationship

scientific article published on January 2009

Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease

scientific article published on 18 April 2009

Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons

scientific article published on 01 October 1995

Neutron Activation Analysis of Trace Elements in Motor Neuron Disease Spinal Cord

article

Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations

scientific article published on 01 June 2006

Omega-3 fatty acids: potential role in the management of early Alzheimer's disease

scientific article

Opposing actions of native and oxidized lipoprotein on motor neuron-like cells.

scientific article published on May 1999

Organoselenium (Sel-Plex diet) decreases amyloid burden and RNA and DNA oxidative damage in APP/PS1 mice

scientific article published on 19 March 2009

Oxidation of cytosolic proteins and expression of creatine kinase BB in frontal lobe in different neurodegenerative disorders

scientific article published in March 1999

Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease

scientific article

Oxidative alterations in Alzheimer's disease

scientific article published in January 1999

Oxidative damage in brain from human mutant APP/PS-1 double knock-in mice as a function of age.

scientific article published on 16 August 2008

Oxidative damage in mild cognitive impairment and early Alzheimer's disease

scientific article published on November 2007

Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease.

scientific article

Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis

scientific article published on 13 June 2005

Oxidative modification of creatine kinase BB in Alzheimer's disease brain.

scientific article published in June 2000

Oxidative stress in head trauma in aging

scientific article published on 3 April 2006

Oxidatively modified RNA in mild cognitive impairment

scientific article published on September 2007

Oxidized low-density lipoprotein induces neuronal death: implications for calcium, reactive oxygen species, and caspases

scientific article published in June 1999

Parkinsonian signs and substantia nigra neuron density in decendents elders without PD

scientific article published on 01 October 2004

Periventricular white matter hyperintensities on MRI: correlation with neuropathologic findings

scientific article published on 01 January 2000

Pharmacokinetics, pharmacodynamics, and safety of metrifonate in patients with Alzheimer's disease

scientific article published in March 1998

Possible involvement of proteasome inhibition in aging: implications for oxidative stress.

scientific article

Postoperative radiotherapy in the treatment of single metastases to the brain: a randomized trial

scientific article published in November 1998

Potential in vivo amelioration by N-acetyl-L-cysteine of oxidative stress in brain in human double mutant APP/PS-1 knock-in mice: toward therapeutic modulation of mild cognitive impairment

scientific article published on September 2010

Preclinical Alzheimer disease: brain oxidative stress, Abeta peptide and proteomics

scientific article

Predicting happiness among centenarians

scientific article

Prodromal clinical manifestations of neuropathologically confirmed Lewy body disease

scientific article

Progression of regional neuropathology in Alzheimer disease and normal elderly: findings from the Nun study.

scientific article published in October 1999

Proteasome inhibition increases DNA and RNA oxidation in astrocyte and neuron cultures.

scientific article published in December 2004

Proteasome inhibition induces reversible impairments in protein synthesis.

scientific article published in June 2006

Proteasome inhibition results in increased poly-ADP-ribosylation: implications for neuron death

scientific article published on August 2000

Protection against amyloid beta peptide and iron/hydrogen peroxide toxicity by alpha lipoic acid

scientific article published in June 2003

Protection against amyloid beta peptide toxicity by zinc

scientific article published in March 1999

Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients

scientific article published on 01 November 1998

Protein oxidation in the brain in Alzheimer's disease

scientific article published in January 2001

Proteomic analysis of brain proteins in APP/PS-1 human double mutant knock-in mice with increasing amyloid β-peptide deposition: insights into the effects of in vivo treatment with N-acetylcysteine as a potential therapeutic intervention in mild cog

scientific article published on 22 September 2011

Proteomic identification of HNE-bound proteins in early Alzheimer disease: Insights into the role of lipid peroxidation in the progression of AD.

scientific article

Proteomic identification of nitrated brain proteins in early Alzheimer's disease inferior parietal lobule

scientific article

Proteomic identification of nitrated proteins in Alzheimer's disease brain

scientific article

Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1.

scientific article

Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71.

scientific article published in September 2002

Proteomic identification of specifically carbonylated brain proteins in APP(NLh)/APP(NLh) × PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice model of Alzheimer disease as a function of age

scientific article published on 25 June 2011

Quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease

scientific article published in January 2001

Quantitative changes in the mitochondrial proteome from subjects with mild cognitive impairment, early stage, and late stage Alzheimer's disease

scientific article

Quantitative proteomic analysis of mitochondria from primary neuron cultures treated with amyloid beta peptide

scientific article

Ratio of 8-hydroxyguanine in intact DNA to free 8-hydroxyguanine is increased in Alzheimer disease ventricular cerebrospinal fluid

scientific article published in March 2001

Reactive oxygen species as causal agents in the neurotoxicity of the Alzheimer's disease-associated amyloid beta peptide

scientific article published on June 1996

Recent clinical-pathologic research on the causes of dementia in late life: update from the Honolulu-Asia Aging Study.

scientific article published in December 2005

Redox Proteomics Analysis of Brains from Subjects with Amnestic Mild Cognitive Impairment Compared to Brains from Subjects with Preclinical Alzheimer's Disease: Insights into Memory Loss in MCI ⬇️

scientific article published on January 1, 2011

Redox proteomic identification of 4-hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease

scientific article

Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease

scientific article published on 8 February 2006

Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: an approach to understand pathological and biochemical alterations in AD.

scientific article published on 4 November 2005

Regional brain trace-element studies in Alzheimer's disease

scientific article published on January 1, 1988

Regional membrane phospholipid alterations in Alzheimer's disease

scientific article published in January 1998

Relative preservation of MMSE scores in autopsy-proven dementia with Lewy bodies

scientific article published on October 2009

Review of 38 cases of subacute sclerosing panencephalitis: effect of amantadine on the natural course of the disease

scientific article published on October 1980

Ribosome dysfunction is an early event in Alzheimer's disease.

scientific article

Risk factors for transitions from normal to mild cognitive impairment and dementia.

scientific article published in March 2006

SV-40 virus-induced neoplastic transformation of hamster brain cells in vitro. Studies with scanning and transmission electron microscopy

scientific article published in November 1982

Scanning electron microscopy studies of erythrocytes in Huntington's Disease ⬇️

scientific article published on September 23, 1977

Seleno-L-methionine protects against beta-amyloid and iron/hydrogen peroxide-mediated neuron death

scientific article

Serum folate and the severity of atrophy of the neocortex in Alzheimer disease: findings from the Nun study

scientific article published on 01 April 2000

Serum zinc in the progression of Alzheimer's disease.

scientific article

Serum zinc, senile plaques, and neurofibrillary tangles: findings from the Nun Study.

scientific article published in November 1995

Social resources and longevity: findings from the Georgia centenarian study

scientific article

Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological diseases: Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and Duchenne muscular dystrophy

scientific article published on January 1, 1979

Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological disorders--Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and duchenne muscular dystrophy

scientific article

Spin label and biochemical studies of erythrocyte membranes in Alzheimer's disease ⬇️

scientific article published on March 1, 1980

Spin labeling studies of membrane proteins in erythrocyte ghosts from patients with Huntington's disease

scientific article

Standardization in biological analyses of aluminum: what are the needs?

scientific article published on August 1996

Survival of hippocampal and cortical neurons in a mixture of MEM+ and B27-supplemented neurobasal medium

scientific article published on 01 March 2000

TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations

scientific article published in February 2007

Tau gene mutation in familial progressive subcortical gliosis

scientific article published in April 1999

Temporal relations among amyloid beta-peptide-induced free-radical oxidative stress, neuronal toxicity, and neuronal defensive responses

scientific article published in December 1998

The Expression of Creatine Kinase Isoenzymes in Neocortex of Patients with Neurodegenerative Disorders: Alzheimer's and Pick's Disease ⬇️

scientific article published on August 1, 1997

The expression of key oxidative stress-handling genes in different brain regions in Alzheimer's disease

scientific article published in October 1998

The expression of several mitochondrial and nuclear genes encoding the subunits of electron transport chain enzyme complexes, cytochrome c oxidase, and NADH dehydrogenase, in different brain regions in Alzheimer's disease

scientific article published in June 1999

The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42.

scientific article published in July 2001

The magnitude of brain lipid peroxidation correlates with the extent of degeneration but not with density of neuritic plaques or neurofibrillary tangles or with APOE genotype in Alzheimer's disease patients

scientific article published on September 1999

Time-dependence of, and effects of inhibition and cellular aging on, chloride efflux across erythrocyte membranes in Huntington's disease ⬇️

scientific article published on November 1, 1982

Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal

scientific article published on 29 May 2008

Trace element content in fingernails and hair of a nonindustrialized US control population

scientific article

Trace element imbalances in amyotrophic lateral sclerosis

scientific article published on 01 January 1990

Trace element imbalances in hair and nails of Alzheimer's disease patients.

scientific article

Trace element imbalances in isolated subcellular fractions of Alzheimer's disease brains

scientific article published in November 1990

Trace elements in Alzheimer's disease pituitary glands

scientific article published in April 1998

Transplantation of pituitary grafts fail to restore immune function and to reconstitute the thymus glands of aged mice

scientific article

Understanding dementia prevalence among centenarians.

scientific article published in March 2012

Urban-rural differences in a memory disorders clinical population

scientific article published on May 2001

Use of bomb pulse carbon-14 to age senile plaques and neurofibrillary tangles in Alzheimer's disease.

scientific article

Vulnerability of synaptosomes from apoE knock-out mice to structural and oxidative modifications induced by A beta(1-40): implications for Alzheimer's disease.

scientific article published in February 2001

White matter volumes and periventricular white matter hyperintensities in aging and dementia.

scientific article published in February 2000

Wilms' tumor suppressor (WT1) is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer's disease

scientific article

beta-amyloid is different in normal aging and in Alzheimer disease.

scientific article published on 15 August 2005

p38 kinase is activated in the Alzheimer's disease brain

scientific article published in May 1999

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