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List of works by Massimo Dominici

A Novel 3D In Vitro Platform for Pre-Clinical Investigations in Drug Testing, Gene Therapy, and Immuno-oncology

article

A novel anti-GD2/4-1BB chimeric antigen receptor triggers neuroblastoma cell killing.

scientific article

A novel function for amniotic fluid: original or authentic?

scientific article published on 23 September 2014

Adipose stromal/stem cells assist fat transplantation reducing necrosis and increasing graft performance.

scientific article published on October 2013

Adipose-derived mesenchymal stem cells as stable source of tumor necrosis factor-related apoptosis-inducing ligand delivery for cancer therapy

scientific article published on 13 April 2010

Altered pH gradient at the plasma membrane of osteosarcoma cells is a key mechanism of drug resistance.

scientific article published on 22 August 2016

An Alternative Approach to Investigate Biofilm in Medical Devices: A Feasibility Study

scientific article published on 18 December 2017

Angiogenesis in multiple myeloma: correlation between in vitro endothelial colonies growth (CFU-En) and clinical–biological features

scientific article published on 01 January 2001

Animal serum-free culture conditions for isolation and expansion of multipotent mesenchymal stromal cells from human BM.

scientific article published in January 2006

Application of multipotent mesenchymal stromal cells in pediatric patients following allogeneic stem cell transplantation

scientific article published on 14 September 2007

Author Correction: A Novel 3D In Vitro Platform for Pre-Clinical Investigations in Drug Testing, Gene Therapy, and Immuno-oncology

scientific article published on 30 January 2020

Basic research and clinical applications of non-hematopoietic stem cells, 4–5 April 2008, Tübingen, Germany

article

Blocking Tumor-Educated MSC Paracrine Activity Halts Osteosarcoma Progression

scientific article published on 4 January 2017

CD271 mediates stem cells to early progeny transition in human epidermis

scientific article published on 20 October 2014

CD34(+) cell subsets and long-term culture colony-forming cells evaluated on both autologous and normal bone marrow stroma predict long-term hematopoietic engraftment in patients undergoing autologous peripheral blood stem cell transplantation.

scientific article

Carbonic anhydrase IX inhibition is an effective strategy for osteosarcoma treatment

scientific article published on 10 September 2015

Cell therapies for pancreatic beta-cell replenishment

scientific article

Cell therapy for disorders of bone.

scientific article published on January 2009

Challenges in Clinical Development of Mesenchymal Stromal/Stem Cells: Concise Review

scientific article published on 16 July 2019

Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement.

scientific article

Clinical perspectives of mesenchymal stem cells

scientific article published on 24 December 2012

Comparison of single and dual platform methodologies for the estimation of CD34+ hematopoietic progenitor cells: correlation with colony assay

scientific article published on 01 October 2002

Concise Review: An (Im)Penetrable Shield: How the Tumor Microenvironment Protects Cancer Stem Cells.

scientific article published on 16 February 2017

Cytokine-induced osteopoietic differentiation of transplanted marrow cells.

scientific article

Delayed marrow infusion in mice enhances hematopoietic and osteopoietic engraftment by facilitating transient expansion of the osteoblastic niche.

scientific article published on 2 August 2013

Detection of microparticles from human red blood cells by multiparametric flow cytometry.

scientific article

Discordance in receptor status between primary and recurrent breast cancer has a prognostic impact: a single-institution analysis

scientific article published on 20 September 2012

Effects of a ceramic biomaterial on immune modulatory properties and differentiation potential of human mesenchymal stromal cells of different origin.

scientific article published on 11 December 2014

Epidermal growth factor receptor (EGFR) high gene copy number and activating mutations in lung adenocarcinomas are not consistently accompanied by positivity for EGFR protein by standard immunohistochemistry.

scientific article

Extracellular vesicles derived from mesenchymal cells: perspective treatment for cutaneous wound healing in pediatrics

scientific article published on 01 June 2018

Extracellular vesicles released from mesenchymal stromal cells stimulate bone growth in osteogenesis imperfecta.

scientific article published on 26 October 2017

Feasibility and safety of treating non-unions in tibia, femur and humerus with autologous, expanded, bone marrow-derived mesenchymal stromal cells associated with biphasic calcium phosphate biomaterials in a multicentric, non-comparative trial.

scientific article published on 19 March 2018

Functional and immunophenotypic characteristics of isolated CD105+ and fibroblast+ stromal cells from AML: implications for their plasticity along endothelial lineage

scientific article published on 01 January 2003

GD2 expression in breast cancer.

scientific article

GMP-manufactured density gradient media for optimized mesenchymal stromal/stem cell isolation and expansion

scientific article published on 01 July 2010

Genomic and functional comparison of mesenchymal stromal cells prepared using two isolation methods

scientific article published in March 2015

Getting beneath the skin to understand MSC complexity.

scientific article published in July 2010

Hematopoietic cells and osteoblasts are derived from a common marrow progenitor after bone marrow transplantation.

scholarly article

Hematopoietic derived cells do not contribute to osteogenesis as osteoblasts

scientific article published on 7 October 2016

How do mesenchymal stromal cells exert their therapeutic benefit?

scientific article published on January 2008

Human Herpes simplex 1 virus infection of endometrial decidual tissue-derived MSC alters HLA-G expression and immunosuppressive functions

scientific article published on 14 August 2018

Human bone marrow mesenchymal stromal cells express the neural ganglioside GD2: a novel surface marker for the identification of MSCs.

scientific article published on 30 January 2007

Human multipotent mesenchymal stromal cells use galectin-1 to inhibit immune effector cells

scientific article published on 19 July 2010

IGF-1-mediated osteoblastic niche expansion enhances long-term hematopoietic stem cell engraftment after murine bone marrow transplantation.

scientific article published in October 2013

Impact of HOXB7 overexpression on human adipose-derived mesenchymal progenitors

scientific article published on 19 March 2019

Impact of time to surgery after neoadjuvant chemotherapy in operable breast cancer patients

scientific article published on 20 October 2016

Impressive Response to Dose-Dense Chemotherapy in a Patient with NUT Midline Carcinoma.

scientific article published on 3 July 2015

Improved isolation and expansion of bone marrow mesenchymal stromal cells using a novel marrow filter device.

scientific article published on 6 December 2012

In vitro and in vivo discrepancy in inducing apoptosis by mesenchymal stromal cells delivering membrane-bound tumor necrosis factor–related apoptosis inducing ligand in osteosarcoma pre-clinical models

scientific article published in August 2018

In vitro anti-myeloma activity of TRAIL-expressing adipose-derived mesenchymal stem cells.

scientific article

In vitro differentiation of human amniotic epithelial cells into insulin-producing 3D spheroids

scientific article

Inducible Caspase9-mediated suicide gene for MSC-based cancer gene therapy

article

Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion

scientific article published on 10 October 2012

International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials

scientific article

Intratumoral Delivery of Interferon γ-secreting MSCs Repolarizes Tumor-Associated Macrophages and Suppresses Neuroblastoma Proliferation In Vivo

scientific article published on 12 February 2018

Introduction and overview.

scientific article published on 19 September 2017

MSC and Tumors: Homing, Differentiation, and Secretion Influence Therapeutic Potential

scientific article published on 01 January 2013

Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning.

scientific article published on 10 May 2013

Mesenchymal Progenitors Aging Highlights a miR-196 Switch Targeting HOXB7 as Master Regulator of Proliferation and Osteogenesis

scientific article published on 01 March 2015

Mesenchymal progenitors expressing TRAIL induce apoptosis in sarcomas

scientific article

Mesenchymal stem cell biodistribution, migration, and homing in vivo

scientific article published on 11 March 2014

Mesenchymal stem/stromal cells as a delivery platform in cell and gene therapies

scientific article

Mesenchymal stromal cells for cutaneous wound healing in a rabbit model: pre-clinical study applicable in the pediatric surgical setting.

scientific article published on 8 July 2015

Mesenchymal stromal/stem cells markers in the human bone marrow

scientific article published on 09 January 2013

Microglia are less pro-inflammatory than myeloid infiltrates in the hippocampus of mice exposed to status epilepticus.

scientific article published on June 2016

Mineralization by mesenchymal stromal cells is variously modulated depending on commercial platelet lysate preparations

scientific article published on 27 December 2017

Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

scientific article (publication date: 2006)

On the development of cell therapy for genetic disorders.

scientific article

PCR with degenerate primers for highly conserved DNA polymerase gene of the herpesvirus family shows neither human herpesvirus 8 nor a related variant in bone marrow stromal cells from multiple myeloma patients

article

Part 1: Defining unproven cellular therapies.

scientific article published in January 2016

Part 2: Making the "unproven" "proven".

scientific article published in January 2016

Part 5: Unproven cell therapies and the commercialization of cell-based products

scientific article published on 01 January 2016

Positioning a Scientific Community on Unproven Cellular Therapies: The 2015 International Society for Cellular Therapy Perspective

scientific article published in December 2015

Potency Biomarker Signature Genes from Multiparametric Osteogenesis Assays: Will cGMP Human Bone Marrow Mesenchymal Stromal Cells Make Bone?

scientific article

Predictors of human epidermal growth factor receptor 2 fluorescence in-situ hybridisation amplification in immunohistochemistry score 2+ infiltrating breast cancer: a single institution analysis

scientific article published on 03 March 2012

President's letter on unproven cellular therapy

scientific article published on 01 January 2016

Proceedings of the signature series symposium "cellular therapies for orthopaedics and musculoskeletal disease proven and unproven therapies-promise, facts and fantasy," international society for cellular therapies, montreal, canada, may 2, 2018

article

Progress in characterization, preparation and clinical applications of non-hematopoietic stem cells, 29–30 September 2006, Tübingen, Germany

article

Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation

scientific article

Prolonged remission state of refractory adult onset Still's disease following CD34-selected autologous peripheral blood stem cell transplantation

scientific article published on 01 June 2000

Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria

scientific article published on 23 September 2006

Rare breast cancer subtypes: histological, molecular, and clinical peculiarities

scientific article

Resistance to neoplastic transformation of ex-vivo expanded human mesenchymal stromal cells after exposure to supramaximal physical and chemical stress.

scientific article published on 15 October 2016

Response to Nature commentary "Clear up this stem-cell mess"

scientific article published on 12 December 2018

Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation.

scientific article published on 11 May 2009

Role of mesenchymal stem cells in osteosarcoma and metabolic reprogramming of tumor cells.

scientific article published on September 2014

Safety Profile of Good Manufacturing Practice Manufactured Interferon γ-Primed Mesenchymal Stem/Stromal Cells for Clinical Trials.

scientific article published on 9 September 2017

Sarcomas as a mise en abyme of mesenchymal stem cells: exploiting interrelationships for cell mediated anticancer therapy.

scientific article published on 29 May 2012

Soluble TRAIL Armed Human MSC As Gene Therapy For Pancreatic Cancer

scientific article published in Scientific Reports

Suppression of invasion and metastasis of triple-negative breast cancer lines by pharmacological or genetic inhibition of slug activity

scientific article

Surrounding pancreatic adenocarcinoma by killer mesenchymal stromal/stem cells.

scientific article

TRAIL delivered by mesenchymal stromal/stem cells counteracts tumor development in orthotopic Ewing sarcoma models

scientific article published on 25 August 2016

Targeting GD2-positive glioblastoma by chimeric antigen receptor empowered mesenchymal progenitors

scientific article published on 22 November 2018

The Survey on Cellular and Engineered Tissue Therapies in Europe in 2013.

scientific article published on 9 December 2015

The puzzling situation of hospital exemption for advanced therapy medicinal products in Europe and stakeholders' concerns

scientific article published on 5 October 2014

Therapeutic potential of the metabolic modulator phenformin in targeting the stem cell compartment in melanoma.

scientific article published on 28 December 2016

Toward cell therapy using placenta-derived cells: disease mechanisms, cell biology, preclinical studies, and regulatory aspects at the round table.

scientific article published on February 2010

Transcriptional link between blood and bone: the stem cell leukemia gene and its +19 stem cell enhancer are active in bone cells

scientific article

Transgenic mice with pancellular enhanced green fluorescent protein expression in primitive hematopoietic cells and all blood cell progeny.

scientific article published in May 2005

Transplanted bone marrow mononuclear cells and MSCs impart clinical benefit to children with osteogenesis imperfecta through different mechanisms.

scientific article

Transplanted murine long-term repopulating hematopoietic cells can differentiate to osteoblasts in the marrow stem cell niche

scientific article published on 16 April 2013

Transportation conditions for prompt use of ex vivo expanded and freshly harvested clinical-grade bone marrow mesenchymal stromal/stem cells for bone regeneration

scientific article published on 20 August 2013

Trophoblast stem cells rescue placental defect in SOCS3-deficient mice

scientific article published on 3 March 2006

Tumor Stroma Manipulation By MSC.

scientific article published on 7 March 2016

cGMP-compliant transportation conditions for a prompt therapeutic use of marrow mesenchymal stromal/stem cells

scientific article published on 01 January 2015