List of works - Luigi Anastasia

A chemical approach to myocardial protection and regeneration.

scientific article

Activation of the hypoxia-inducible factor 1α promotes myogenesis through the noncanonical Wnt pathway, leading to hypertrophic myotubes.

scientific article published on 10 February 2017

Application of direct HPTLC-MALDI for the qualitative and quantitative profiling of neutral and acidic glycosphingolipids: the case of NEU3 overexpressing C2C12 murine myoblasts.

scientific article

Being a Scientist today: are you still having fun? ⬇️

scientific article published on October 11, 2012

Calcium in Brugada Syndrome: Questions for Future Research

scientific article published on 10 August 2018

Cardiac Niche Influences the Direct Reprogramming of Canine Fibroblasts into Cardiomyocyte-Like Cells.

scientific article

Cell reprogramming: a new chemical approach to stem cell biology and tissue regeneration.

scientific article published on February 2011

Cell reprogramming: expectations and challenges for chemistry in stem cell biology and regenerative medicine

scientific article

Cell-Based Therapies for Cardiac Regeneration: A Comprehensive Review of Past and Ongoing Strategies

scientific article published on 16 October 2018

Chemical Activation of the Hypoxia-Inducible Factor Reversibly Reduces Tendon Stem Cell Proliferation, Inhibits Their Differentiation, and Maintains Cell Undifferentiation.

scientific article published on 11 March 2018

Circulating S100B and Adiponectin in Children Who Underwent Open Heart Surgery and Cardiopulmonary Bypass

scientific article

Commentary: Next Generation Sequencing and Linkage Analysis for the Molecular Diagnosis of a Novel Overlapping Syndrome Characterized by Hypertrophic Cardiomyopathy and Typical Electrical Instability of Brugada Syndrome

scientific article published on 12 December 2017

Deep learning unmasks the ECG signature of Brugada syndrome

scientific article published in November 2023

Down regulation of membrane-bound Neu3 constitutes a new potential marker for childhood acute lymphoblastic leukemia and induces apoptosis suppression of neoplastic cells.

scientific article

Effects of the pulsed electromagnetic field PST® on human tendon stem cells: a controlled laboratory study

scientific article

Elucidation of several neglected reactions in the GC-MS identification of sialic acids as heptafluorobutyrates calls for an urgent reassessment of previous claims

scientific article published on 01 May 2015

Expression of sialidase Neu2 in leukemic K562 cells induces apoptosis by impairing Bcr-Abl/Src kinases signaling

scientific article published on 20 March 2007

GM1 Ganglioside Promotes Osteogenic Differentiation of Human Tendon Stem Cells

scientific article published on 23 August 2018

Gangliosides as a potential new class of stem cell markers: the case of GD1a in human bone marrow mesenchymal stem cells

scientific article published on 21 January 2014

Genotype-Phenotype Correlation in a Family with Brugada Syndrome Harboring the Novel p.Gln371* Nonsense Variant in the SCN5A Gene

scientific article published on 06 November 2019

Glutathione Blood Concentrations: A Biomarker of Oxidative Damage Protection during Cardiopulmonary Bypass in Children

scientific article published on 13 September 2019

Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis

scientific article published in 2024

Highly satisfactory alkynylation of alkenyl halides via Pd-catalyzed cross-coupling with alkynylzincs and its critical comparison with the sonogashira alkynylation

scientific article published on 01 May 2003

Highly satisfactory procedures for the Pd-catalyzed cross coupling of aryl electrophiles with in situ generated alkynylzinc derivatives

scientific article published on 01 October 2001

Identification of lysosomal sialidase NEU1 and plasma membrane sialidase NEU3 in human erythrocytes

scientific article published on 01 January 2013

Insulin-like growth factor-1 receptor identifies a pool of human cardiac stem cells with superior therapeutic potential for myocardial regeneration

scientific article published on 5 May 2011

Intrinsic cell memory reinforces myogenic commitment of pericyte-derived iPSCs

scientific article published on 21 February 2011

Lipogems Product Treatment Increases the Proliferation Rate of Human Tendon Stem Cells without Affecting Their Stemness and Differentiation Capability

scientific article published on 6 January 2016

Long-term results of sequential vein coronary artery bypass grafting compared with totally arterial myocardial revascularization: a propensity score-matched follow-up study

scientific article published on 13 March 2014

Modification of sialidase levels and sialoglycoconjugate pattern during erythroid and erytroleukemic cell differentiation

scientific article published on 01 January 2007

Molecular subtyping of metastatic melanoma based on cell ganglioside metabolism profiles.

scientific article

NEU3 Sialidase Protein Interactors in the Plasma Membrane and in the Endosomes

scientific article published on 17 March 2016

NEU3 sialidase is activated under hypoxia and protects skeletal muscle cells from apoptosis through the activation of the epidermal growth factor receptor signaling pathway and the hypoxia-inducible factor (HIF)-1α

scientific article published on 3 December 2012

NEU3 sialidase role in activating HIF-1α in response to chronic hypoxia in cyanotic congenital heart patients.

scientific article published on 21 December 2016

NEU3 sialidase strictly modulates GM3 levels in skeletal myoblasts C2C12 thus favoring their differentiation and protecting them from apoptosis.

scientific article published on 22 October 2008

NEU4L sialidase overexpression promotes β-catenin signaling in neuroblastoma cells, enhancing stem-like malignant cell growth.

scientific article published on 9 March 2012

Novel SCN5A p.V1429M Variant Segregation in a Family with Brugada Syndrome

scientific article published on 17 August 2020

Novel SCN5A p.W697X Nonsense Mutation Segregation in a Family with Brugada Syndrome

scientific article published on 04 October 2019

Over-expression of mammalian sialidase NEU3 reduces Newcastle disease virus entry and propagation in COS7 cells.

scientific article published on 4 December 2007

Palladium-catalyzed alkynylation.

scientific article

Potent Inhibitors against Newcastle Disease Virus Hemagglutinin-Neuraminidase

scientific article published on 12 December 2017

Proteomic signature of reversine-treated murine fibroblasts by 2-D difference gel electrophoresis and MS: possible associations with cell signalling networks.

scientific article published in June 2009

Regenerating the human heart: direct reprogramming strategies and their current limitations

scientific article published on 27 October 2017

Reversine increases multipotent human mesenchymal cells differentiation potential

scientific article published on 01 April 2011

Reversine-treated fibroblasts acquire myogenic competence in vitro and in regenerating skeletal muscle.

scientific article published on 26 May 2006

Right ventricular epicardial arrhythmogenic substrate in long-QT syndrome patients at risk of sudden death

S100B increases in cyanotic versus noncyanotic infants undergoing heart surgery and cardiopulmonary bypass (CPB).

scientific article published on 28 November 2017

Sialidase NEU3 is a peripheral membrane protein localized on the cell surface and in endosomal structures

scientific article

Synthesis and biological evaluation of several dephosphonated analogues of CMP-Neu5Ac as inhibitors of GM3-synthase

scientific article published on 11 August 2015

Synthesis and chemical characterization of several perfluorinated sialic acid glycals and evaluation of their in vitro antiviral activity against Newcastle disease virus

scientific article published on 05 June 2017

Synthetic sulfonyl-hydrazone-1 positively regulates cardiomyogenic microRNA expression and cardiomyocyte differentiation of induced pluripotent stem cells ⬇️

scientific article published on August 1, 2011

The Substrate of Sudden Death in Long-QT Syndrome is localized in the Epicardium

The plasma membrane sialidase NEU3 regulates the malignancy of renal carcinoma cells by controlling β1 integrin internalization and recycling

scientific article

The plasma membrane-associated sialidase MmNEU3 modifies the ganglioside pattern of adjacent cells supporting its involvement in cell-to-cell interactions.

scientific article published on 16 February 2004

The synthetic purine reversine selectively induces cell death of cancer cells

scientific article

List of works by Luigi Anastasia

A chemical approach to myocardial protection and regeneration.

Activation of the hypoxia-inducible factor 1α promotes myogenesis through the noncanonical Wnt pathway, leading to hypertrophic myotubes.

Application of direct HPTLC-MALDI for the qualitative and quantitative profiling of neutral and acidic glycosphingolipids: the case of NEU3 overexpressing C2C12 murine myoblasts.

Being a Scientist today: are you still having fun? ⬇️

Calcium in Brugada Syndrome: Questions for Future Research

Cardiac Niche Influences the Direct Reprogramming of Canine Fibroblasts into Cardiomyocyte-Like Cells.

Cell reprogramming: a new chemical approach to stem cell biology and tissue regeneration.

Cell reprogramming: expectations and challenges for chemistry in stem cell biology and regenerative medicine

Cell-Based Therapies for Cardiac Regeneration: A Comprehensive Review of Past and Ongoing Strategies

Chemical Activation of the Hypoxia-Inducible Factor Reversibly Reduces Tendon Stem Cell Proliferation, Inhibits Their Differentiation, and Maintains Cell Undifferentiation.

Circulating S100B and Adiponectin in Children Who Underwent Open Heart Surgery and Cardiopulmonary Bypass

Commentary: Next Generation Sequencing and Linkage Analysis for the Molecular Diagnosis of a Novel Overlapping Syndrome Characterized by Hypertrophic Cardiomyopathy and Typical Electrical Instability of Brugada Syndrome

Deep learning unmasks the ECG signature of Brugada syndrome

Down regulation of membrane-bound Neu3 constitutes a new potential marker for childhood acute lymphoblastic leukemia and induces apoptosis suppression of neoplastic cells.

Effects of the pulsed electromagnetic field PST® on human tendon stem cells: a controlled laboratory study

Elucidation of several neglected reactions in the GC-MS identification of sialic acids as heptafluorobutyrates calls for an urgent reassessment of previous claims

Expression of sialidase Neu2 in leukemic K562 cells induces apoptosis by impairing Bcr-Abl/Src kinases signaling

GM1 Ganglioside Promotes Osteogenic Differentiation of Human Tendon Stem Cells

Gangliosides as a potential new class of stem cell markers: the case of GD1a in human bone marrow mesenchymal stem cells

Genotype-Phenotype Correlation in a Family with Brugada Syndrome Harboring the Novel p.Gln371* Nonsense Variant in the SCN5A Gene

Glutathione Blood Concentrations: A Biomarker of Oxidative Damage Protection during Cardiopulmonary Bypass in Children

Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis

Highly satisfactory alkynylation of alkenyl halides via Pd-catalyzed cross-coupling with alkynylzincs and its critical comparison with the sonogashira alkynylation

Highly satisfactory procedures for the Pd-catalyzed cross coupling of aryl electrophiles with in situ generated alkynylzinc derivatives

Identification of lysosomal sialidase NEU1 and plasma membrane sialidase NEU3 in human erythrocytes

Insulin-like growth factor-1 receptor identifies a pool of human cardiac stem cells with superior therapeutic potential for myocardial regeneration

Intrinsic cell memory reinforces myogenic commitment of pericyte-derived iPSCs

Lipogems Product Treatment Increases the Proliferation Rate of Human Tendon Stem Cells without Affecting Their Stemness and Differentiation Capability

Long-term results of sequential vein coronary artery bypass grafting compared with totally arterial myocardial revascularization: a propensity score-matched follow-up study

Modification of sialidase levels and sialoglycoconjugate pattern during erythroid and erytroleukemic cell differentiation

Molecular subtyping of metastatic melanoma based on cell ganglioside metabolism profiles.

NEU3 Sialidase Protein Interactors in the Plasma Membrane and in the Endosomes

NEU3 sialidase is activated under hypoxia and protects skeletal muscle cells from apoptosis through the activation of the epidermal growth factor receptor signaling pathway and the hypoxia-inducible factor (HIF)-1α

NEU3 sialidase role in activating HIF-1α in response to chronic hypoxia in cyanotic congenital heart patients.

NEU3 sialidase strictly modulates GM3 levels in skeletal myoblasts C2C12 thus favoring their differentiation and protecting them from apoptosis.

NEU4L sialidase overexpression promotes β-catenin signaling in neuroblastoma cells, enhancing stem-like malignant cell growth.

Novel SCN5A p.V1429M Variant Segregation in a Family with Brugada Syndrome

Novel SCN5A p.W697X Nonsense Mutation Segregation in a Family with Brugada Syndrome

Over-expression of mammalian sialidase NEU3 reduces Newcastle disease virus entry and propagation in COS7 cells.

Palladium-catalyzed alkynylation.

Potent Inhibitors against Newcastle Disease Virus Hemagglutinin-Neuraminidase

Proteomic signature of reversine-treated murine fibroblasts by 2-D difference gel electrophoresis and MS: possible associations with cell signalling networks.

Regenerating the human heart: direct reprogramming strategies and their current limitations

Reversine increases multipotent human mesenchymal cells differentiation potential

Reversine-treated fibroblasts acquire myogenic competence in vitro and in regenerating skeletal muscle.

Right ventricular epicardial arrhythmogenic substrate in long-QT syndrome patients at risk of sudden death

S100B increases in cyanotic versus noncyanotic infants undergoing heart surgery and cardiopulmonary bypass (CPB).

Sialidase NEU3 is a peripheral membrane protein localized on the cell surface and in endosomal structures

Synthesis and biological evaluation of several dephosphonated analogues of CMP-Neu5Ac as inhibitors of GM3-synthase

Synthesis and chemical characterization of several perfluorinated sialic acid glycals and evaluation of their in vitro antiviral activity against Newcastle disease virus

Synthetic sulfonyl-hydrazone-1 positively regulates cardiomyogenic microRNA expression and cardiomyocyte differentiation of induced pluripotent stem cells ⬇️

The Substrate of Sudden Death in Long-QT Syndrome is localized in the Epicardium

The plasma membrane sialidase NEU3 regulates the malignancy of renal carcinoma cells by controlling β1 integrin internalization and recycling

The plasma membrane-associated sialidase MmNEU3 modifies the ganglioside pattern of adjacent cells supporting its involvement in cell-to-cell interactions.

The synthetic purine reversine selectively induces cell death of cancer cells