List of works - Mary G Sorci-Thomas

A consensus model of human apolipoprotein A-I in its monomeric and lipid-free state.

scientific article published on 13 November 2017

AIBP, NAXE, and Angiogenesis: What's in a Name?

scientific article

Acrolein impairs the cholesterol transport functions of high density lipoproteins.

scientific article

Alpha-tocopherol protects against diet induced atherosclerosis in New Zealand white rabbits.

scientific article published in November 2002

Anti-inflammatory liaisons: T regulatory cells and HDL

scientific article published on 19 June 2017

Apolipoprotein A-I Modulates Regulatory T Cells in Autoimmune LDLr−/−, ApoA-I−/− Mice ⬇️

scientific article published on September 10, 2010

Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution

scientific journal article

Apolipoprotein A-I helix 6 negatively charged residues attenuate lecithin-cholesterol acyltransferase (LCAT) reactivity.

scientific article

Associations of ApoAI and ApoB-containing lipoproteins with AngII-induced abdominal aortic aneurysms in mice

scientific article published on 4 June 2015

Corticotropin releasing factor mRNA and peptide levels are differentially regulated in the developing ovine brain.

scientific article published in November 1994

Cortisol up-regulates corticotropin releasing factor gene expression in the fetal ovine brainstem at 0.70 gestation.

scientific article published in August 1995

Cytokines decrease apolipoprotein accumulation in medium from Hep G2 cells.

scientific article published on January 1994

Dexamethasone increases apolipoprotein A-I concentrations in medium and apolipoprotein A-I mRNA abundance from Hep G2 cells

scientific article published on 01 October 1992

Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet

scientific article published on 13 October 2005

Endothelial Rap1 (Ras-Association Proximate 1) Restricts Inflammatory Signaling to Protect From the Progression of Atherosclerosis

scientific article published on 03 December 2020

Estrogen modulates the inducible expression of platelet-derived growth factor mRNA by monocyte/macrophages.

scientific article published on January 1995

Genetic deletion of apolipoprotein A-I increases airway hyperresponsiveness, inflammation, and collagen deposition in the lung.

scientific article

Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein.

scientific article published on 06 December 2013

High-Density Lipoprotein Biogenesis: Defining the Domains Involved in Human Apolipoprotein A-I Lipidation

scientific article published on 08 August 2016

Induction of fatal inflammation in LDL receptor and ApoA-I double-knockout mice fed dietary fat and cholesterol.

scientific article published on September 2003

Inflammation and skin cholesterol in LDLr-/-, apoA-I-/- mice: link between cholesterol homeostasis and self-tolerance?

scientific journal article

Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis

scientific article published on 08 November 2018

Intermolecular contact between globular N-terminal fold and C-terminal domain of ApoA-I stabilizes its lipid-bound conformation: studies employing chemical cross-linking and mass spectrometry.

scientific article published on 22 June 2005

Isoprostane levels in lipids extracted from atherosclerotic arteries of nonhuman primates.

scientific article published in June 2001

Lipid-Free Apolipoprotein A-I Reduces Progression of Atherosclerosis by Mobilizing Microdomain Cholesterol and Attenuating the Number of CD131 Expressing Cells: Monitoring Cholesterol Homeostasis Using the Cellular Ester to Total Cholesterol Ratio.

scientific article

Lipin-1 contributes to modified low-density lipoprotein-elicited macrophage pro-inflammatory responses.

scientific article

Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis.

scientific article

Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice

scientific article published on 25 March 2013

Macrophage apoAI protects against dyslipidemia-induced dermatitis and atherosclerosis without affecting HDL.

scientific article

Microdomains, Inflammation, and Atherosclerosis.

scientific article published on February 2016

Myeloperoxidase Inhibition Ameliorates Plaque Psoriasis in Mice

scientific article published in 2021

Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers

scientific article

Procollagen C-endopeptidase Enhancer Protein 2 (PCPE2) Reduces Atherosclerosis in Mice by Enhancing Scavenger Receptor Class B1 (SR-BI)-mediated High-density Lipoprotein (HDL)-Cholesteryl Ester Uptake

scientific article published on 6 May 2015

Quality control in the apoA-I secretory pathway: deletion of apoA-I helix 6 leads to the formation of cytosolic phospholipid inclusions.

scientific article published on April 2004

Ratio determination of plasma wild-type and L159R apoA-I using mass spectrometry: tools for studying apoA-IFin

scientific article published on 28 October 2006

Rediscovering scavenger receptor type BI: surprising new roles for the HDL receptor.

scientific article published on 15 March 2017

Regulation of high-density lipoprotein on hematopoietic stem/progenitor cells in atherosclerosis requires scavenger receptor type BI expression

scientific article

S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization.

scientific article published on 23 November 2016

SAA: a link between cholesterol efflux capacity and inflammation?

scientific article published on 15 June 2015

Sex steroids increase cholesterol 7alpha-hydroxylase mRNA in nonhuman primates.

scientific article published in April 1998

Single repeat deletion in ApoA-I blocks cholesterol esterification and results in rapid catabolism of delta6 and wild-type ApoA-I in transgenic mice

scientific article published on 01 April 2000

Species-specific polymorphism in the promoter of the apolipoprotein A-I gene: restoration of human transcriptional efficiency by substitution at positions -189, -144 and -48 bp.

scientific article

Structural determination of lipid-bound ApoA-I using fluorescence resonance energy transfer

scientific article published on 01 November 2000

Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression

scientific article

The conformation of lipid-free human apolipoprotein A-I in solution

scientific article published on 17 December 2013

The hydrophobic face orientation of apolipoprotein A-I amphipathic helix domain 143-164 regulates lecithin:cholesterol acyltransferase activation

scientific article published on 01 May 1998

The ins and outs of lipid rafts: Functions in intracellular cholesterol homeostasis, microparticles, and cell membranes

scientific article published on 30 December 2019

The use of chemical cross-linking and mass spectrometry to elucidate the tertiary conformation of lipid-bound apolipoprotein A-I.

scientific article

Thermoneutrality but Not UCP1 Deficiency Suppresses Monocyte Mobilization Into Blood.

scientific article published on 10 July 2017

Three-dimensional models of HDL apoA-I: implications for its assembly and function.

scientific article published on 30 May 2008

What does procollagen C-endopeptidase enhancer protein 2 have to do with HDL-cholesteryl ester uptake? Or how I learned to stop worrying and love reverse cholesterol transport?

scientific article

Why targeting HDL should work as a therapeutic tool, but has not.

scientific article published on September 2013

List of works by Mary G Sorci-Thomas

A consensus model of human apolipoprotein A-I in its monomeric and lipid-free state.

AIBP, NAXE, and Angiogenesis: What's in a Name?

Acrolein impairs the cholesterol transport functions of high density lipoproteins.

Alpha-tocopherol protects against diet induced atherosclerosis in New Zealand white rabbits.

Anti-inflammatory liaisons: T regulatory cells and HDL

Apolipoprotein A-I Modulates Regulatory T Cells in Autoimmune LDLr−/−, ApoA-I−/− Mice ⬇️

Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution

Apolipoprotein A-I helix 6 negatively charged residues attenuate lecithin-cholesterol acyltransferase (LCAT) reactivity.

Associations of ApoAI and ApoB-containing lipoproteins with AngII-induced abdominal aortic aneurysms in mice

Corticotropin releasing factor mRNA and peptide levels are differentially regulated in the developing ovine brain.

Cortisol up-regulates corticotropin releasing factor gene expression in the fetal ovine brainstem at 0.70 gestation.

Cytokines decrease apolipoprotein accumulation in medium from Hep G2 cells.

Dexamethasone increases apolipoprotein A-I concentrations in medium and apolipoprotein A-I mRNA abundance from Hep G2 cells

Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet

Endothelial Rap1 (Ras-Association Proximate 1) Restricts Inflammatory Signaling to Protect From the Progression of Atherosclerosis

Estrogen modulates the inducible expression of platelet-derived growth factor mRNA by monocyte/macrophages.

Genetic deletion of apolipoprotein A-I increases airway hyperresponsiveness, inflammation, and collagen deposition in the lung.

Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein.

High-Density Lipoprotein Biogenesis: Defining the Domains Involved in Human Apolipoprotein A-I Lipidation

Induction of fatal inflammation in LDL receptor and ApoA-I double-knockout mice fed dietary fat and cholesterol.

Inflammation and skin cholesterol in LDLr-/-, apoA-I-/- mice: link between cholesterol homeostasis and self-tolerance?

Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis

Intermolecular contact between globular N-terminal fold and C-terminal domain of ApoA-I stabilizes its lipid-bound conformation: studies employing chemical cross-linking and mass spectrometry.

Isoprostane levels in lipids extracted from atherosclerotic arteries of nonhuman primates.

Lipid-Free Apolipoprotein A-I Reduces Progression of Atherosclerosis by Mobilizing Microdomain Cholesterol and Attenuating the Number of CD131 Expressing Cells: Monitoring Cholesterol Homeostasis Using the Cellular Ester to Total Cholesterol Ratio.

Lipin-1 contributes to modified low-density lipoprotein-elicited macrophage pro-inflammatory responses.

Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis.

Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice

Macrophage apoAI protects against dyslipidemia-induced dermatitis and atherosclerosis without affecting HDL.

Microdomains, Inflammation, and Atherosclerosis.

Myeloperoxidase Inhibition Ameliorates Plaque Psoriasis in Mice

Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers

Procollagen C-endopeptidase Enhancer Protein 2 (PCPE2) Reduces Atherosclerosis in Mice by Enhancing Scavenger Receptor Class B1 (SR-BI)-mediated High-density Lipoprotein (HDL)-Cholesteryl Ester Uptake

Quality control in the apoA-I secretory pathway: deletion of apoA-I helix 6 leads to the formation of cytosolic phospholipid inclusions.

Ratio determination of plasma wild-type and L159R apoA-I using mass spectrometry: tools for studying apoA-IFin

Rediscovering scavenger receptor type BI: surprising new roles for the HDL receptor.

Regulation of high-density lipoprotein on hematopoietic stem/progenitor cells in atherosclerosis requires scavenger receptor type BI expression

S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization.

SAA: a link between cholesterol efflux capacity and inflammation?

Sex steroids increase cholesterol 7alpha-hydroxylase mRNA in nonhuman primates.

Single repeat deletion in ApoA-I blocks cholesterol esterification and results in rapid catabolism of delta6 and wild-type ApoA-I in transgenic mice

Species-specific polymorphism in the promoter of the apolipoprotein A-I gene: restoration of human transcriptional efficiency by substitution at positions -189, -144 and -48 bp.

Structural determination of lipid-bound ApoA-I using fluorescence resonance energy transfer

Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression

The conformation of lipid-free human apolipoprotein A-I in solution

The hydrophobic face orientation of apolipoprotein A-I amphipathic helix domain 143-164 regulates lecithin:cholesterol acyltransferase activation

The ins and outs of lipid rafts: Functions in intracellular cholesterol homeostasis, microparticles, and cell membranes

The use of chemical cross-linking and mass spectrometry to elucidate the tertiary conformation of lipid-bound apolipoprotein A-I.

Thermoneutrality but Not UCP1 Deficiency Suppresses Monocyte Mobilization Into Blood.

Three-dimensional models of HDL apoA-I: implications for its assembly and function.

What does procollagen C-endopeptidase enhancer protein 2 have to do with HDL-cholesteryl ester uptake? Or how I learned to stop worrying and love reverse cholesterol transport?

Why targeting HDL should work as a therapeutic tool, but has not.