List of works by Ruben Boon

A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma

scientific article published on 22 February 2021

Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines

scientific article published on 13 March 2020

Breast cancer cells rely on environmental pyruvate to shape the metastatic niche

scientific article published on 27 February 2019

Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors

scientific article

Dynamic regulation of EZH2 from HPSc to hepatocyte-like cell fate.

scientific article published in November 2017

Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition

scientific article

Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

scientific article published in Nature

Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis

scientific article published on 28 June 2018

H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In Vitro

scientific article published on 27 July 2016

HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations

scientific article published on 10 March 2021

HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients

scientific article published on 11 October 2017

Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways

scientific article published on 9 November 2015

Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2

scientific article published on 12 November 2018

Nuclear metabolism and the regulation of the epigenome

scientific article published on 12 October 2020

PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells

scientific article published on 14 January 2021

Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells

scientific article

Rapid and Efficient Generation of Recombinant Human Pluripotent Stem Cells by Recombinase-mediated Cassette Exchange in the AAVS1 Locus

scientific article published on 20 November 2016

Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis

scientific article published on 08 February 2016

SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells

scientific article published on 10 January 2018

Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication

scientific article

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