List of works - Peter Arvan

"Register-shift" insulin analogs uncover constraints of proteotoxicity in protein evolution

scientific article published on 31 January 2020

Biosynthesis, structure, and folding of the insulin precursor protein

scientific article published on 01 September 2018

Cells Deploy a Two-Pronged Strategy to Rectify Misfolded Proinsulin Aggregates

scientific article published on 05 June 2019

Chaperone-Driven Degradation of a Misfolded Proinsulin Mutant in Parallel With Restoration of Wild-Type Insulin Secretion.

scientific article published on 27 December 2016

Distinct states of proinsulin misfolding in MIDY

scientific article published on 10 July 2021

ER-associated degradation is required for vasopressin prohormone processing and systemic water homeostasis.

scientific article

Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity.

scientific article published on 19 February 2018

Increased mitochondrial respiration promotes survival from endoplasmic reticulum stress

scientific article published on 23 May 2018

Lessons from animal models of endocrine disorders caused by defects of protein folding in the secretory pathway

scientific article published on 09 October 2019

Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes.

scientific article

PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity.

scientific article published on 11 June 2019

Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes

scientific article published on 10 December 2018

Proinsulin misfolding is an early event in the progression to type 2 diabetes.

scientific article published on 11 June 2019

Response to Comment on Sims et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258-264

scientific article published on 01 May 2019

Reticulon protects the integrity of the ER membrane during ER escape of large macromolecular protein complexes

scientific article published on 01 February 2020

The role of thyroglobulin in thyroid hormonogenesis

scientific article published on 01 June 2019

The structure of natively iodinated bovine thyroglobulin

Thyrocyte cell survival and adaptation to chronic endoplasmic reticulum stress due to misfolded thyroglobulin

scientific article published on 02 April 2020

XB130 Deficiency Causes Congenital Hypothyroidism in Mice due to Disorganized Apical Membrane Structure and Function of Thyrocytes

scientific article published in 2021

List of works by Peter Arvan