List of works - Donata Medaglini

A Stochastic Model for CD4+ T Cell Proliferation and Dissemination Network in Primary Immune Response

scientific article published on 24 August 2015

A dose-dependent plasma signature of the safety and immunogenicity of the rVSV-Ebola vaccine in Europe and Africa.

scientific article published on April 2017

ADITEC: joining forces for next-generation vaccines

scientific article published on April 2012

Adoptive transfer of transgenic T cells to study mucosal adjuvants

scientific article published on 04 May 2009

Assessment of mucosal immunity to HIV-1.

scientific article published on April 2010

Big science for vaccine development

article

CD4(+) T Cell Priming as Biomarker to Study Immune Response to Preventive Vaccines

scientific article

Characterization of the Antigen-Specific CD4(+) T Cell Response Induced by Prime-Boost Strategies with CAF01 and CpG Adjuvants Administered by the Intranasal and Subcutaneous Routes

scientific article

Commensal bacteria as vectors for mucosal vaccines against sexually transmitted diseases: vaginal colonization with recombinant streptococci induces local and systemic antibodies in mice

scientific article published on 01 August 1997

Correlates of vaccine-induced protective immunity against Ebola virus disease

Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study

article by Angela Huttner et al published July 2018 in Lancet Infectious Diseases

Distribution of primed T cells and antigen-loaded antigen presenting cells following intranasal immunization in mice

scientific article

Ebola vaccine R&D: Filling the knowledge gaps.

scientific article

Engineering the gram-positive cell surface for construction of bacterial vaccine vectors.

scientific article

Genetic engineering of Streptococcus gordonii for the simultaneous display of two heterologous proteins at the bacterial surface.

scientific article

Gram-positive commensal bacteria for mucosal vaccine delivery.

scientific article

Heterologous Prime-Boost Combinations Highlight the Crucial Role of Adjuvant in Priming the Immune System.

scientific article

Human T-helper cell recognition of an immunodominant epitope of HIV-1 gp120 expressed on the surface of Streptococcus gordonii.

scientific article published on September 1994

Identification of a branching process model for adaptive immune response

Immunity against HIV/AIDS, Malaria, and Tuberculosis during Co-Infections with Neglected Infectious Diseases: Recommendations for the European Union Research Priorities

scientific article

Immunization with recombinant Streptococcus gordonii expressing tetanus toxin fragment C confers protection from lethal challenge in mice

scientific article published on 01 February 2001

Immunization with the conjugate vaccine Vi-CRM₁₉₇ against Salmonella typhi induces Vi-specific mucosal and systemic immune responses in mice

scientific article published on 15 June 2012

Immunogenicity of a Bivalent Adjuvanted Glycoconjugate Vaccine against Salmonella Typhimurium and Salmonella Enteritidis

scientific article published on 27 February 2017

Immunogenicity of the B monomer of Escherichia coli heat-labile toxin expressed on the surface of Streptococcus gordonii.

scientific article

Immunoglobulin-binding domains of peptostreptococcal protein L enhance vaginal colonization of mice by Streptococcus gordonii

scientific article published on 01 April 2001

Immunomonitoring of human responses to the rVSV-ZEBOV Ebola vaccine

scientific article

In vivo activation of naive CD4+ T cells in nasal mucosa-associated lymphoid tissue following intranasal immunization with recombinant Streptococcus gordonii

scientific article published on May 2006

In vivo mucosal delivery of bioactive human interleukin 1 receptor antagonist produced by Streptococcus gordonii

scientific article

Innovation Partnership for a Roadmap on Vaccines in Europe (IPROVE): A vision for the vaccines of tomorrow

scientific article published on 29 January 2018

Interferon-γ from Brain Leukocytes Enhances Meningitis by Type 4 Streptococcus pneumoniae

scientific article

Intranasal administration of the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei with the modified heat-labile toxin of Escherichia coli (LTK63) induces a complete protection against malaria challenge

scientific article published on 26 December 2008

Intranasal immunization of mice with recombinant Streptococcus gordonii expressing NadA of Neisseria meningitidis induces systemic bactericidal antibodies and local IgA.

scientific article

Intranasal immunization with vaccine vector Streptococcus gordonii elicits primed CD4+ and CD8+ T cells in the genital and intestinal tracts

scientific article published on 27 November 2009

Modulation of Primary Immune Response by Different Vaccine Adjuvants

scientific article published on 17 October 2016

Mucosal Adjuvants

scientific article published on 01 June 2010

Mucosal and systemic immune responses to a recombinant protein expressed on the surface of the oral commensal bacterium Streptococcus gordonii after oral colonization

scientific article

O:2-CRM(197) conjugates against Salmonella Paratyphi A.

scientific article

Peptide-specific T helper cells identified by MHC class II tetramers differentiate into several subtypes upon immunization with CAF01 adjuvanted H56 tuberculosis vaccine formulation

scientific article published on 20 October 2015

Primary activation of antigen-specific naive CD4+ and CD8+ T cells following intranasal vaccination with recombinant bacteria

scientific article published on 06 October 2008

Prime-boost strategies in mucosal immunization affect local IgA production and the type of th response

scientific article published on 29 May 2013

Recombinant Gram-positive bacteria as vehicles of vaccine antigens

article by Donata Medaglini et al published 1997 in Biotechnology Annual Review

Role of the Microbiota in the Modulation of Vaccine Immune Responses

scientific article published on 03 July 2019

Shelter from the cytokine storm: pitfalls and prospects in the development of SARS-CoV-2 vaccines for an elderly population

scientific article published on 06 November 2020

Stimulation of human monocytes with the gram-positive vaccine vector Streptococcus gordonii

scientific article published on September 2006

Surface display of recombinant proteins on Bacillus subtilis spores.

scientific article

The European effort towards the development of mucosal vaccines for poverty-related diseases

scientific article published on 03 March 2009

The European research effort for HIV/AIDS, malaria and tuberculosis

scientific article published in June 2003

The microbicide cyanovirin-N expressed on the surface of commensal bacterium Streptococcus gordonii captures HIV-1.

scientific article published in July 2002

The role of the vaccines industry in Mission Grand Convergence

scientific article published on 22 December 2016

Transcriptomics of the Vaccine Immune Response: Priming With Adjuvant Modulates Recall Innate Responses After Boosting.

scientific article published on 5 June 2018

Using IFN-gamma release assay to confirm tuberculin skin test improves the screening of latent tuberculosis infection in Italian healthcare workers

scientific article published on 07 June 2016

Vaccination in the elderly: The challenge of immune changes with aging

scientific article published on 01 December 2018

Vaccine adjuvants: a priority for vaccine research

scientific article published on 9 January 2010

Vaginal immunization to elicit primary T-cell activation and dissemination

scientific article

Vaginal immunization with recombinant gram-positive bacteria.

scientific article published on March 1998

List of works by Donata Medaglini

A Stochastic Model for CD4+ T Cell Proliferation and Dissemination Network in Primary Immune Response

A dose-dependent plasma signature of the safety and immunogenicity of the rVSV-Ebola vaccine in Europe and Africa.

ADITEC: joining forces for next-generation vaccines

Adoptive transfer of transgenic T cells to study mucosal adjuvants

Assessment of mucosal immunity to HIV-1.

Big science for vaccine development

CD4(+) T Cell Priming as Biomarker to Study Immune Response to Preventive Vaccines

Characterization of the Antigen-Specific CD4(+) T Cell Response Induced by Prime-Boost Strategies with CAF01 and CpG Adjuvants Administered by the Intranasal and Subcutaneous Routes

Commensal bacteria as vectors for mucosal vaccines against sexually transmitted diseases: vaginal colonization with recombinant streptococci induces local and systemic antibodies in mice

Correlates of vaccine-induced protective immunity against Ebola virus disease

Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study

Distribution of primed T cells and antigen-loaded antigen presenting cells following intranasal immunization in mice

Ebola vaccine R&D: Filling the knowledge gaps.

Engineering the gram-positive cell surface for construction of bacterial vaccine vectors.

Genetic engineering of Streptococcus gordonii for the simultaneous display of two heterologous proteins at the bacterial surface.

Gram-positive commensal bacteria for mucosal vaccine delivery.

Heterologous Prime-Boost Combinations Highlight the Crucial Role of Adjuvant in Priming the Immune System.

Human T-helper cell recognition of an immunodominant epitope of HIV-1 gp120 expressed on the surface of Streptococcus gordonii.

Identification of a branching process model for adaptive immune response

Immunity against HIV/AIDS, Malaria, and Tuberculosis during Co-Infections with Neglected Infectious Diseases: Recommendations for the European Union Research Priorities

Immunization with recombinant Streptococcus gordonii expressing tetanus toxin fragment C confers protection from lethal challenge in mice

Immunization with the conjugate vaccine Vi-CRM₁₉₇ against Salmonella typhi induces Vi-specific mucosal and systemic immune responses in mice

Immunogenicity of a Bivalent Adjuvanted Glycoconjugate Vaccine against Salmonella Typhimurium and Salmonella Enteritidis

Immunogenicity of the B monomer of Escherichia coli heat-labile toxin expressed on the surface of Streptococcus gordonii.

Immunoglobulin-binding domains of peptostreptococcal protein L enhance vaginal colonization of mice by Streptococcus gordonii

Immunomonitoring of human responses to the rVSV-ZEBOV Ebola vaccine

In vivo activation of naive CD4+ T cells in nasal mucosa-associated lymphoid tissue following intranasal immunization with recombinant Streptococcus gordonii

In vivo mucosal delivery of bioactive human interleukin 1 receptor antagonist produced by Streptococcus gordonii

Innovation Partnership for a Roadmap on Vaccines in Europe (IPROVE): A vision for the vaccines of tomorrow

Interferon-γ from Brain Leukocytes Enhances Meningitis by Type 4 Streptococcus pneumoniae

Intranasal administration of the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei with the modified heat-labile toxin of Escherichia coli (LTK63) induces a complete protection against malaria challenge

Intranasal immunization of mice with recombinant Streptococcus gordonii expressing NadA of Neisseria meningitidis induces systemic bactericidal antibodies and local IgA.

Intranasal immunization with vaccine vector Streptococcus gordonii elicits primed CD4+ and CD8+ T cells in the genital and intestinal tracts

Modulation of Primary Immune Response by Different Vaccine Adjuvants

Mucosal Adjuvants

Mucosal and systemic immune responses to a recombinant protein expressed on the surface of the oral commensal bacterium Streptococcus gordonii after oral colonization

O:2-CRM(197) conjugates against Salmonella Paratyphi A.

Peptide-specific T helper cells identified by MHC class II tetramers differentiate into several subtypes upon immunization with CAF01 adjuvanted H56 tuberculosis vaccine formulation

Primary activation of antigen-specific naive CD4+ and CD8+ T cells following intranasal vaccination with recombinant bacteria

Prime-boost strategies in mucosal immunization affect local IgA production and the type of th response

Recombinant Gram-positive bacteria as vehicles of vaccine antigens

Role of the Microbiota in the Modulation of Vaccine Immune Responses

Shelter from the cytokine storm: pitfalls and prospects in the development of SARS-CoV-2 vaccines for an elderly population

Stimulation of human monocytes with the gram-positive vaccine vector Streptococcus gordonii

Surface display of recombinant proteins on Bacillus subtilis spores.

The European effort towards the development of mucosal vaccines for poverty-related diseases

The European research effort for HIV/AIDS, malaria and tuberculosis

The microbicide cyanovirin-N expressed on the surface of commensal bacterium Streptococcus gordonii captures HIV-1.

The role of the vaccines industry in Mission Grand Convergence

Transcriptomics of the Vaccine Immune Response: Priming With Adjuvant Modulates Recall Innate Responses After Boosting.

Using IFN-gamma release assay to confirm tuberculin skin test improves the screening of latent tuberculosis infection in Italian healthcare workers

Vaccination in the elderly: The challenge of immune changes with aging

Vaccine adjuvants: a priority for vaccine research

Vaginal immunization to elicit primary T-cell activation and dissemination

Vaginal immunization with recombinant gram-positive bacteria.