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List of works by Karl-Johan Malmberg

A short-term dietary supplementation of high doses of vitamin E increases T helper 1 cytokine production in patients with advanced colorectal cancer

scientific article

A short-term dietary supplementation with high doses of vitamin E increases NK cell cytolytic activity in advanced colorectal cancer patients.

scientific article published on 2 December 2006

Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease

scientific article published on 22 May 2014

Activating NK-cell receptors co-stimulate CD4+CD28−T cells in patients with rheumatoid arthritis

scientific article published on 01 February 2010

Analysis of the KIR repertoire in human NK cells by flow cytometry

scientific article

Application of nine-color flow cytometry for detailed studies of the phenotypic complexity and functional heterogeneity of human lymphocyte subsets

scientific article

Bioinformatics approaches to profile the tumor microenvironment for immunotherapeutic discovery

scientific article published on 10 July 2017

CD56bright NK cells exhibit potent antitumor responses following IL-15 priming

scientific article published on 3 October 2017

CD8 T cells express randomly selected KIRs with distinct specificities compared with NK cells

scientific article

CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients

scientific article

Characterization of natural killer cell phenotype and function during recurrent human HSV-2 infection

scientific article

Class I HLA haplotypes form two schools that educate NK cells in different ways

scientific article published on 09 September 2016

Classification of human natural killer cells based on migration behavior and cytotoxic response.

scientific article published on 3 January 2013

Cognate HLA absence in trans diminishes human NK cell education

scientific article published on 29 August 2016

Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML.

scientific article published on 14 February 2018

Coordinated expression of DNAM-1 and LFA-1 in educated NK cells

scientific article published on 30 March 2015

Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans.

scientific article published on 20 April 2016

Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function

scientific article

DNAX Accessory Molecule-1 Mediated Recognition of Freshly Isolated Ovarian Carcinoma by Resting Natural Killer Cells

scientific article published on 01 February 2007

Deciphering Natural Killer Cell Homeostasis

scientific article published on 12 May 2020

Distinct infiltration of neutrophils in lesion shoulders in ApoE-/- mice.

scientific article published on 14 May 2010

Education of human natural killer cells by activating killer cell immunoglobulin-like receptors

scientific article published on 10 November 2009

Effective immunotherapy against cancer: a question of overcoming immune suppression and immune escape?

scientific article published on 28 July 2004

Effects of HDV infection and pegylated interferon α treatment on the natural killer cell compartment in chronically infected individuals

scientific article published on 10 April 2014

Elevated numbers of Fc gamma RIIIA+ (CD16+) effector CD8 T cells with NK cell-like function in chronic hepatitis C virus infection.

scientific article published on September 2008

Escape from immune- and nonimmune-mediated tumor surveillance.

scientific article

Estimation of the size of the alloreactive NK cell repertoire: studies in individuals homozygous for the group A KIR haplotype

scientific article published in November 2008

Ex Vivo Expanded Adaptive NK Cells Effectively Kill Primary Acute Lymphoblastic Leukemia Cells.

scientific article

Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education

article

First International Meeting of the Thematic Centre for Immune Modulatory Therapies for Autoimmunity and Cancer (IMTAC) 13-14 June 2011, Ljusterö, Sweden.

scientific article published on 15 January 2012

Frequent loss of HLA-A2 expression in metastasizing ovarian carcinomas associated with genomic haplotype loss and HLA-A2-restricted HER-2/neu-specific immunity.

scientific article published on June 2006

Harnessing adaptive natural killer cells in cancer immunotherapy

scientific article

IFN-gamma production dominates the early human natural killer cell response to Coxsackievirus infection

scientific article published on 24 October 2007

IFN-gamma protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanism

scientific article

IFN-γ protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanism

scientific article published on 15 November 2002

Identification of a novel KIR3DL1*072 allele by sequence-based typing

scientific article published in February 2010

Imbalance of Genes Encoding Natural Killer Immunoglobulin-Like Receptors and Human Leukocyte Antigen in Patients With Biliary Cancer

scientific article published on 21 June 2019

Immune selection during tumor checkpoint inhibition therapy paves way for NK-cell "missing self" recognition

scientific article

Impact of KIR and HLA Genotypes on Outcomes after Reduced-Intensity Conditioning Hematopoietic Cell Transplantation

scientific article

Imprint of 5-azacytidine on the natural killer cell repertoire during systemic treatment for high-risk myelodysplastic syndrome.

scientific article published on 21 October 2015

Improved Survival after Allogeneic Hematopoietic Stem Cell Transplantation in Recent Years. A Single-Center Study

scientific article published on 11 May 2011

Increased Infection-Related Mortality in KIR-Ligand???Mismatched Unrelated Allogeneic Hematopoietic Stem-Cell Transplantation

scientific article published in October 2004

Increased incidence of chronic GvHD and CMV disease in patients with vitamin D deficiency before allogeneic stem cell transplantation.

scientific article published on June 2015

Independent skewing of the T cell and NK cell compartments associated with cytomegalovirus infection suggests division of labor between innate and adaptive immunity.

scientific article

Induction of the BIM Short Splice Variant Sensitizes Proliferating NK Cells to IL-15 Withdrawal

scientific article published on 21 December 2018

Influence of KIR gene copy number on natural killer cell education

scientific article published on May 2013

Interactions of NK cell receptor KIR3DL1*004 with chaperones and conformation-specific antibody reveal a functional folded state as well as predominant intracellular retention

scientific article

Intra-lineage Plasticity and Functional Reprogramming Maintain Natural Killer Cell Repertoire Diversity

scientific article published on 01 November 2019

Intra-lineage Plasticity and Functional Reprogramming Maintain Natural Killer Cell Repertoire Diversity: Supplementary Figures

scholarly article published 9 January 2019

Intrinsic Functional Potential of NK-Cell Subsets Constrains Retargeting Driven by Chimeric Antigen Receptors.

scientific article published on 19 February 2018

KIR acquisition probabilities are independent of self-HLA class I ligands and increase with cellular KIR expression

scientific article published on 20 March 2009

KIR-ligand mismatch in allogeneic hematopoietic stem cell transplantation.

scientific article

Killer Cell Immunoglobulin-like Receptor Workshop: Insights into Evolution, Genetics, Function, and Translation

scientific article published in November 2011

Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity

scientific article published on 10 June 2020

Microchip-Based Single-Cell Imaging Reveals That CD56dimCD57-KIR-NKG2A+ NK Cells Have More Dynamic Migration Associated with Increased Target Cell Conjugation and Probability of Killing Compared to CD56dimCD57-KIR-NKG2A- NK Cells.

scientific article published on 28 August 2015

Modulation of Secretory Lysosomes During NK Cell Education Leads to Accumulation of Granzyme B and Enhanced Functional Potential

NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs

scientific article published on 16 January 2013

NK cell-mediated targeting of human cancer and possibilities for new means of immunotherapy

scientific article published on 04 March 2008

NK cells expressing inhibitory KIR for non-self-ligands remain tolerant in HLA-matched sibling stem cell transplantation

scientific article

NKG2D performs two functions in invariant NKT cells: direct TCR-independent activation of NK-like cytolysis and co-stimulation of activation by CD1d

scientific article

Naive Donor NK Cell Repertoires Associated with Less Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation.

scientific article published on 8 January 2016

Natural Killer Cells in the Treatment of Human Cancer

scientific article published on 28 September 2009

Natural killer cell immunotypes related to COVID-19 disease severity

scientific article published on 01 August 2020

Natural killer cell inhibitory receptor expression in humans and mice: a closer look

scientific article published on 26 March 2013

Natural killer cell-mediated immunosurveillance of human cancer.

scientific article published on 6 September 2017

Natural killer cell-mediated lysis of freshly isolated human tumor cells.

scientific article published on February 2009

Newtonian cell interactions shape natural killer cell education

scientific article

Off-the-shelf cell therapy with induced pluripotent stem cell-derived natural killer cells

scientific article published on 25 October 2018

Polyclonal Expansion of NKG2C(+) NK Cells in TAP-Deficient Patients

scientific article

Preferential cell death of CD8+ effector memory (CCR7-CD45RA-) T cells by hydrogen peroxide-induced oxidative stress

scientific article

Primary human tumor cells expressing CD155 impair tumor targeting by down-regulating DNAM-1 on NK cells

scientific article

Prospects for the use of NK cells in immunotherapy of human cancer.

scientific article published on May 2007

Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus. ⬇️

scientific article

Reduced DNAM-1 expression on bone marrow NK cells associated with impaired killing of CD34+ blasts in myelodysplastic syndrome.

scientific article published on 8 July 2010

Regulation of interleukin-4 signaling by extracellular reduction of intramolecular disulfides

scientific article published on 28 October 2009

Remodeling of secretory lysosomes during education tunes functional potential in NK cells

scientific article published in Nature Communications

Role for early-differentiated natural killer cells in infectious mononucleosis

scientific article

Selenite induces posttranscriptional blockade of HLA-E expression and sensitizes tumor cells to CD94/NKG2A-positive NK cells.

scientific article

Spotlight on IL-22-producing NK cell receptor-expressing mucosal lymphocytes.

scientific article

Spotlight on NKG2C and the human NK-cell response to CMV infection

scientific article published on December 2012

Systemic and Intra-Nodal Activation of NK Cells After Rituximab Monotherapy for Follicular Lymphoma

scientific article published on 12 September 2019

T Cell Infiltrates in the Muscles of Patients with Dermatomyositis and Polymyositis Are Dominated by CD28null T Cells

scientific article published on 14 September 2009

TRP Channels as Interior Designers: Remodeling the Endolysosomal Compartment in Natural Killer Cells

scientific article published on 28 April 2020

Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA

scientific article published on 18 February 2016

The CD16- CD56(bright) NK cell subset is resistant to reactive oxygen species produced by activated granulocytes and has higher antioxidative capacity than the CD16+ CD56(dim) subset.

scientific article

Tolerant and diverse natural killer cell repertoires in the absence of selection

scientific article published on 03 March 2010

Toward a prime-boost regime for NK cells?

scientific article published on 6 December 2012

Tracing dynamic expansion of human NK-cell subsets by high-resolution analysis of KIR repertoires and cellular differentiation

scientific article published on 7 May 2014

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