List of works - Hiroshi Nakajima

A functional polymorphism in B and T lymphocyte attenuator is associated with susceptibility to rheumatoid arthritis

scientific article

A patient with neuromyelitis optica with positive anti-Ro (SS-A) antibody presenting with intractable hiccup and nausea

AT-Rich-Interactive Domain-Containing Protein 5A Functions as a Negative Regulator of Retinoic Acid Receptor-Related Orphan Nuclear Receptor γt-Induced Th17 Cell Differentiation

scientific article published on 01 May 2014

Aerosolized recombinant interferon-gamma prevents antigen-induced eosinophil recruitment in mouse trachea

scientific article published on 01 October 1993

Allergic airway inflammation: key players beyond the Th2 cell pathway.

scientific article published on July 2017

An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction

scientific article published on 01 November 1997

B and T lymphocyte attenuator inhibits LPS-induced endotoxic shock by suppressing Toll-like receptor 4 signaling in innate immune cells.

scientific article published on 11 March 2013

B and T lymphocyte attenuator inhibits antigen-induced eosinophil recruitment into the airways

scientific article published on 01 May 2007

Bucillamine-induced yellow nail in Japanese patients with rheumatoid arthritis: two case reports and a review of 36 reported cases

scientific article

CD4+ T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea

scientific article published on 01 August 1992

CD4-CD8- T cells bearing invariant Valpha24JalphaQ TCR alpha-chain are decreased in patients with atopic diseases

scientific article published on 01 March 2000

Caprylic acid and medium-chain triglycerides inhibit IL-8 gene transcription in Caco-2 cells: comparison with the potent histone deacetylase inhibitor trichostatin A.

scientific article published in May 2002

Clinical characteristics and risk factors for Pneumocystis jirovecii pneumonia in patients with rheumatoid arthritis receiving adalimumab: a retrospective review and case-control study of 17 patients.

scientific article published on 05 December 2012

Clinical characteristics and risk factors for Pneumocystis jirovecii pneumonia in patients with rheumatoid arthritis receiving adalimumab: a retrospective review and case–control study of 17 patients

scholarly article by Kaori Watanabe et al published 5 December 2012 in Modern Rheumatology

Clinical characteristics of Nocardia infection in patients with rheumatic diseases

scientific article published on 19 September 2013

Coinhibitory molecules in autoimmune diseases.

scientific article published on 11 September 2012

Corticosteroid-sparing effect of tacrolimus in the initial treatment of dermatomyositis and polymyositis

scientific article

Critical Roles of IĸB Kinase Subunits in Mast Cell Degranulation ⬇️

scientific article published on May 15, 2012

Effect of a selective thromboxane A2 receptor antagonist BAY u3405 on antigen-, leukotriene C4- and leukotriene D4-induced bronchoconstriction in guinea pigs

scientific article published on 01 September 1995

Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2–induced lung exudative vasculitis and predicts COVID-19 severity

scientific article published in 2022

Eosinophilic Fasciitis Illustrated by [(18)F] FDG-PET/CT

scientific article published on 15 August 2016

Essential Role of Stat5 for IL-5-Dependent IgH Switch Recombination in Mouse B Cells ⬇️

scientific article published on November 1, 2001

Extracorporeal membrane oxygenation is indicated for status asthmaticus refractory to maximal conventional therapy.

scientific article published on 29 January 2013

Functional cleavage of the common cytokine receptor gamma chain (gammac) by calpain

scientific article

Helios Enhances Treg Cell Function in Cooperation With FoxP3.

scientific article published on June 2015

High-dose oral tolerance prevents antigen-induced eosinophil recruitment into the mouse airways ⬇️

scientific article published on April 1, 1998

IL-22 attenuates IL-25 production by lung epithelial cells and inhibits antigen-induced eosinophilic airway inflammation

scientific article

IL-22 induces Reg3γ and inhibits allergic inflammation in house dust mite-induced asthma models.

scientific article published on 15 August 2017

IL-5 and eosinophilia.

scientific article published on 27 May 2008

Impaired peripheral deletion of activated T cells in mice lacking the common cytokine receptor gamma-chain: defective Fas ligand expression in gamma-chain-deficient mice ⬇️

scientific article published on November 15, 1997

Infection of mice lacking the common cytokine receptor gamma-chain (gamma(c)) reveals an unexpected role for CD4+ T lymphocytes in early IFN-gamma-dependent resistance to Toxoplasma gondii ⬇️

scientific article published on March 15, 1998

Interaction between Smad anchor for receptor activation and Smad3 is not essential for TGF-beta/Smad3-mediated signaling.

scientific article

Interferon gamma regulates antigen-induced eosinophil recruitment into the mouse airways by inhibiting the infiltration of CD4+ T cells.

scientific article published on February 1993

Interleukin-21-producing c-Maf-expressing CD4+ T cells induce effector CD8+ T cells and enhance autoimmune inflammation in scurfy mice

scientific article published on 01 August 2014

IκBNS induces Muc5ac expression in epithelial cells and causes airway hyper-responsiveness in murine asthma models

scientific article published on 6 November 2016

Lack of B and T lymphocyte attenuator exacerbates autoimmune disorders and induces Fas-independent liver injury in MRL-lpr/lpr mice

scientific article published on 01 May 2011

Longterm Outcomes of 188 Japanese Patients with Eosinophilic Granulomatosis with Polyangiitis

scientific article published on 15 June 2018

Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

scientific article

Oral mite anaphylaxis caused by mite-contaminated okonomiyaki/ pancake-mix in Japan: 8 case reports and a review of 28 reported cases

scientific article published on March 2014

Overexpression of RORγt under control of the CD2 promoter induces polyclonal plasmacytosis and autoantibody production in transgenic mice ⬇️

scientific article published on July 9, 2012

Overlapping and distinct roles of STAT4 and T-bet in the regulation of T cell differentiation and allergic airway inflammation

scientific article published on 01 May 2008

Preface to the proceedings of the Workshop on Eosinophils in Allergy and Related Diseases 2017

scientific article published on 01 September 2018

Preferentially inflamed tendon sheaths in the swollen but not tender joints in a 5-year-old boy with Blau syndrome.

scientific article published on 26 July 2013

Pressure overload induces cardiac dysfunction and dilation in signal transducer and activator of transcription 6-deficient mice

scientific article published on 18 October 2004

Reply

scientific article published on 01 March 2016

Role of IL-23-Th17 cell axis in allergic airway inflammation.

scientific article published on 03 June 2009

Role of calcium ionophore A23187-induced activation of IkappaB kinase 2 in mast cells.

scientific article published on 29 May 2013

Role of p53 in systemic autoimmune diseases

scientific article

Role of vascular cell adhesion molecule-1 and platelet-activating factor in selective eosinophil migration across vascular endothelial cells

scientific article published on 01 August 1995

Roles of Dectin-1 in Allergic Airway Inflammation

scientific article published in January 2017

Roles of alternatively activated M2 macrophages in allergic contact dermatitis.

scientific article published on 17 March 2017

Roles of mast cells in the pathogenesis of inflammatory myopathy

scientific article

Severity and Diurnal Improvement of Morning Stiffness Independently Associate with Tenosynovitis in Patients with Rheumatoid Arthritis.

scientific article

Sox12 promotes T reg differentiation in the periphery during colitis

scientific article published on 06 September 2018

Sox5 and Th17 cell differentiation

scientific article published on 3 July 2015

Stat5a is essential for the proliferation and survival of murine mast cells

scientific journal article

Stat6-protease but not Stat5-protease is inhibited by an elastase inhibitor ONO-5046.

scientific article

Subtilase Cytotoxin Enhances Escherichia coli Survival in Macrophages by Suppression of Nitric Oxide Production through the Inhibition of NF-κB Activation ⬇️

scientific article published on September 4, 2012

Systemic T helper 2 cell activation is not sufficient for antigen-induced eosinophil recruitment into the airways

scientific article published on 01 May 2000

T cell vaccination eliminates antigen-specific T cells and prevents antigen-induced eosinophil recruitment into the tissue

scientific article published on 01 January 2001

T-bet inhibits both TH2 cell-mediated eosinophil recruitment and TH17 cell-mediated neutrophil recruitment into the airways

scientific article published on 01 March 2007

Transitional changes in the incidence of osteonecrosis in systemic lupus erythematosus patients: focus on immunosuppressant agents and glucocorticoids

scientific article published on 01 May 2018

Tumor Suppressor p53 Functions as a Negative Regulator in IgE-Mediated Mast Cell Activation ⬇️

scientific article published on September 23, 2011

Tumor suppressor p53 inhibits systemic autoimmune diseases by inducing regulatory T cells

scientific article published on 04 September 2013

Tyk2 is essential for IFN-alpha-induced gene expression in mast cells

scientific article published in June 2004

Ultrasound can improve the accuracy of the 2010 American College of Rheumatology/European League against rheumatism classification criteria for rheumatoid arthritis to predict the requirement for methotrexate treatment.

scientific article published in April 2013

List of works by Hiroshi Nakajima

A functional polymorphism in B and T lymphocyte attenuator is associated with susceptibility to rheumatoid arthritis

A patient with neuromyelitis optica with positive anti-Ro (SS-A) antibody presenting with intractable hiccup and nausea

AT-Rich-Interactive Domain-Containing Protein 5A Functions as a Negative Regulator of Retinoic Acid Receptor-Related Orphan Nuclear Receptor γt-Induced Th17 Cell Differentiation

Aerosolized recombinant interferon-gamma prevents antigen-induced eosinophil recruitment in mouse trachea

Allergic airway inflammation: key players beyond the Th2 cell pathway.

An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction

B and T lymphocyte attenuator inhibits LPS-induced endotoxic shock by suppressing Toll-like receptor 4 signaling in innate immune cells.

B and T lymphocyte attenuator inhibits antigen-induced eosinophil recruitment into the airways

Bucillamine-induced yellow nail in Japanese patients with rheumatoid arthritis: two case reports and a review of 36 reported cases

CD4+ T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea

CD4-CD8- T cells bearing invariant Valpha24JalphaQ TCR alpha-chain are decreased in patients with atopic diseases

Caprylic acid and medium-chain triglycerides inhibit IL-8 gene transcription in Caco-2 cells: comparison with the potent histone deacetylase inhibitor trichostatin A.

Clinical characteristics and risk factors for Pneumocystis jirovecii pneumonia in patients with rheumatoid arthritis receiving adalimumab: a retrospective review and case-control study of 17 patients.

Clinical characteristics and risk factors for Pneumocystis jirovecii pneumonia in patients with rheumatoid arthritis receiving adalimumab: a retrospective review and case–control study of 17 patients

Clinical characteristics of Nocardia infection in patients with rheumatic diseases

Coinhibitory molecules in autoimmune diseases.

Corticosteroid-sparing effect of tacrolimus in the initial treatment of dermatomyositis and polymyositis

Critical Roles of IĸB Kinase Subunits in Mast Cell Degranulation ⬇️

Effect of a selective thromboxane A2 receptor antagonist BAY u3405 on antigen-, leukotriene C4- and leukotriene D4-induced bronchoconstriction in guinea pigs

Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2–induced lung exudative vasculitis and predicts COVID-19 severity

Eosinophilic Fasciitis Illustrated by [(18)F] FDG-PET/CT

Essential Role of Stat5 for IL-5-Dependent IgH Switch Recombination in Mouse B Cells ⬇️

Extracorporeal membrane oxygenation is indicated for status asthmaticus refractory to maximal conventional therapy.

Functional cleavage of the common cytokine receptor gamma chain (gammac) by calpain

Helios Enhances Treg Cell Function in Cooperation With FoxP3.

High-dose oral tolerance prevents antigen-induced eosinophil recruitment into the mouse airways ⬇️

IL-22 attenuates IL-25 production by lung epithelial cells and inhibits antigen-induced eosinophilic airway inflammation

IL-22 induces Reg3γ and inhibits allergic inflammation in house dust mite-induced asthma models.

IL-5 and eosinophilia.

Impaired peripheral deletion of activated T cells in mice lacking the common cytokine receptor gamma-chain: defective Fas ligand expression in gamma-chain-deficient mice ⬇️

Infection of mice lacking the common cytokine receptor gamma-chain (gamma(c)) reveals an unexpected role for CD4+ T lymphocytes in early IFN-gamma-dependent resistance to Toxoplasma gondii ⬇️

Interaction between Smad anchor for receptor activation and Smad3 is not essential for TGF-beta/Smad3-mediated signaling.

Interferon gamma regulates antigen-induced eosinophil recruitment into the mouse airways by inhibiting the infiltration of CD4+ T cells.

Interleukin-21-producing c-Maf-expressing CD4+ T cells induce effector CD8+ T cells and enhance autoimmune inflammation in scurfy mice

IκBNS induces Muc5ac expression in epithelial cells and causes airway hyper-responsiveness in murine asthma models

Lack of B and T lymphocyte attenuator exacerbates autoimmune disorders and induces Fas-independent liver injury in MRL-lpr/lpr mice

Longterm Outcomes of 188 Japanese Patients with Eosinophilic Granulomatosis with Polyangiitis

Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

Oral mite anaphylaxis caused by mite-contaminated okonomiyaki/ pancake-mix in Japan: 8 case reports and a review of 28 reported cases

Overexpression of RORγt under control of the CD2 promoter induces polyclonal plasmacytosis and autoantibody production in transgenic mice ⬇️

Overlapping and distinct roles of STAT4 and T-bet in the regulation of T cell differentiation and allergic airway inflammation

Preface to the proceedings of the Workshop on Eosinophils in Allergy and Related Diseases 2017

Preferentially inflamed tendon sheaths in the swollen but not tender joints in a 5-year-old boy with Blau syndrome.

Pressure overload induces cardiac dysfunction and dilation in signal transducer and activator of transcription 6-deficient mice

Reply

Role of IL-23-Th17 cell axis in allergic airway inflammation.

Role of calcium ionophore A23187-induced activation of IkappaB kinase 2 in mast cells.

Role of p53 in systemic autoimmune diseases

Role of vascular cell adhesion molecule-1 and platelet-activating factor in selective eosinophil migration across vascular endothelial cells

Roles of Dectin-1 in Allergic Airway Inflammation

Roles of alternatively activated M2 macrophages in allergic contact dermatitis.

Roles of mast cells in the pathogenesis of inflammatory myopathy

Severity and Diurnal Improvement of Morning Stiffness Independently Associate with Tenosynovitis in Patients with Rheumatoid Arthritis.

Sox12 promotes T reg differentiation in the periphery during colitis

Sox5 and Th17 cell differentiation

Stat5a is essential for the proliferation and survival of murine mast cells

Stat6-protease but not Stat5-protease is inhibited by an elastase inhibitor ONO-5046.

Subtilase Cytotoxin Enhances Escherichia coli Survival in Macrophages by Suppression of Nitric Oxide Production through the Inhibition of NF-κB Activation ⬇️

Systemic T helper 2 cell activation is not sufficient for antigen-induced eosinophil recruitment into the airways

T cell vaccination eliminates antigen-specific T cells and prevents antigen-induced eosinophil recruitment into the tissue

T-bet inhibits both TH2 cell-mediated eosinophil recruitment and TH17 cell-mediated neutrophil recruitment into the airways

Transitional changes in the incidence of osteonecrosis in systemic lupus erythematosus patients: focus on immunosuppressant agents and glucocorticoids

Tumor Suppressor p53 Functions as a Negative Regulator in IgE-Mediated Mast Cell Activation ⬇️

Tumor suppressor p53 inhibits systemic autoimmune diseases by inducing regulatory T cells

Tyk2 is essential for IFN-alpha-induced gene expression in mast cells

Ultrasound can improve the accuracy of the 2010 American College of Rheumatology/European League against rheumatism classification criteria for rheumatoid arthritis to predict the requirement for methotrexate treatment.