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List of works by Babak Razani

78-OR: Adipose Lysosomal Acid Lipase Is Indispensable for Starvation- and Cold-Induced Lipolysis

A CD103+ Conventional Dendritic Cell Surveillance System Prevents Development of Overt Heart Failure during Subclinical Viral Myocarditis.

scientific article published in November 2017

Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation

scientific article published on 20 May 2020

Amino Acid Metabolism and Atherosclerotic Cardiovascular Disease

scientific article published in January 2024

Anti-angiogenic Nanotherapy Inhibits Airway Remodeling and Hyper-responsiveness of Dust Mite Triggered Asthma in the Brown Norway Rat.

scientific article published on January 2017

Assessment of Copper Nanoclusters for Accurate in Vivo Tumor Imaging and Potential for Translation

scientific article published on 22 May 2019

Author Correction: High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy

scientific article published on 09 September 2020

Autophagy is critical for group 2 innate lymphoid cell metabolic homeostasis and effector function

scientific article published on 16 November 2019

Autophagy links inflammasomes to atherosclerotic progression.

scientific article published on 20 March 2012

CRISPR/Cas9-Mediated Gene Editing in Human iPSC-Derived Macrophage Reveals Lysosomal Acid Lipase Function in Human Macrophages-Brief Report

scientific article

Can the DNA damage response be harnessed to modulate atherosclerotic plaque phenotype?

scientific article

Caveolae-deficient Endothelial Cells Show Defects in the Uptake and Transport of Albuminin Vivo

scientific article published in Journal of Biological Chemistry

Caveolae: from cell biology to animal physiology

scientific article

Caveolin-1 Null (−/−) Mice Show Dramatic Reductions in Life Span†

scientific article published on 01 December 2003

Caveolin-1 expression is down-regulated in cells transformed by the human papilloma virus in a p53-dependent manner. Replacement of caveolin-1 expression suppresses HPV-mediated cell transformation.

scientific article

Caveolin-1 inhibits epidermal growth factor-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1.

scientific article

Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia

scientific article published on October 2002

Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities

scientific article published on 5 December 2001

Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade.

scientific article

Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue

scientific article published on 26 March 2003

Caveolin-1/3 double-knockout mice are viable, but lack both muscle and non-muscle caveolae, and develop a severe cardiomyopathic phenotype.

scientific article published on June 2002

Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae

scientific article

Caveolin-deficient mice: insights into caveolar function human disease ⬇️

scientific article published on December 1, 2001

Caveolins and caveolae: molecular and functional relationships.

scientific article

Classical and alternative roles for autophagy in lipid metabolism

scientific article published on 29 March 2018

Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia

scientific article published on 25 March 2004

Degradation and beyond: the macrophage lysosome as a nexus for nutrient sensing and processing in atherosclerosis

scientific article published on August 2015

Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation

scientific article published on January 2014

Emerging themes in lipid rafts and caveolae.

scientific article

Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis.

scientific article

Fatty acid synthase modulates homeostatic responses to myocardial stress.

scientific article

Frontline Science: Acyl-CoA synthetase 1 exacerbates lipotoxic inflammasome activation in primary macrophages

scientific article published on 05 June 2019

Functional Characterization of LIPA (Lysosomal Acid Lipase) Variants Associated With Coronary Artery Disease

scientific article published on 24 October 2019

Getting away from glucose: stop sugarcoating diabetes

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

article by Daniel J Klionsky et al published January 2021 in Autophagy

Heterogeneity in Early Postpartum Metabolic Profiles Among Women with GDM Who Progressed to Type 2 Diabetes During 10-Year Follow-Up: The SWIFT Study

High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy

scientific article published on 23 January 2020

Hypoxia in plaque macrophages: a new danger signal for interleukin-1β activation?

scientific article published on October 2014

Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis

scientific article published on 05 January 2016

Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae

scientific article

Inflammasomes: a preclinical assessment of targeting in atherosclerosis

scientific article published on 06 August 2020

Inhibiting adipose tissue lipogenesis reprograms thermogenesis and PPARγ activation to decrease diet-induced obesity

scientific article

Insulin resistance and atherosclerosis

scientific article published on 01 September 2008

Interleukins and atherosclerosis: a dysfunctional family grows

scientific article

Intermittent Fasting Preserves Beta-Cell Mass in Obesity-induced Diabetes via the Autophagy-Lysosome Pathway

scientific article published on 30 August 2017

Intracellular retention of glycosylphosphatidyl inositol-linked proteins in caveolin-deficient cells.

scientific article published on June 2002

Keap1/Cullin3 Modulates p62/SQSTM1 Activity via UBA Domain Ubiquitination

scientific article published on April 2017

Keap1/Cullin3 Modulates p62/SQSTM1 Activity via UBA Domain Ubiquitination

scientific article

Linking lysosomal acid lipase insufficiency to the development of cryptogenic cirrhosis

scientific article

Lipid-laden foam cells in the pathology of atherosclerosis: shedding light on new therapeutic targets

scientific article published on 28 November 2023

Loss of Macrophage mTORC2 Drives Atherosclerosis via FoxO1 and IL-1β Signaling

scientific article published on 21 July 2023

Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice

scientific article

Low dose chloroquine decreases insulin resistance in human metabolic syndrome but does not reduce carotid intima-media thickness

scientific article published on 29 July 2019

MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression

scientific article published on 01 October 2020

Modulating Oxysterol Sensing to Control Macrophage Apoptosis and Atherosclerosis

scientific article published in December 2016

Molecular cloning and developmental expression of the caveolin gene family in the amphibian Xenopus laevis

scientific article

N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2.

scientific article published on 18 August 2017

Options to consider when treating lysosomal acid lipase deficiency

scientific article published on 25 July 2016

PPARγ Deficiency Suppresses the Release of IL-1β and IL-1α in Macrophages via a Type 1 IFN-Dependent Mechanism

scientific article published on 24 August 2018

Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission

scientific article published on 14 January 2019

Publisher Correction: Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction

scientific article published on 01 May 2019

Regulation of cAMP-mediated signal transduction via interaction of caveolins with the catalytic subunit of protein kinase A

scientific article published on 01 September 1999

Role of caveolin-1 in the modulation of lipolysis and lipid droplet formation

scientific article published in May 2004

Self-eating in the plaque: what macrophage autophagy reveals about atherosclerosis

scientific article published on 17 April 2014

Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction.

scientific article published on 11 December 2018

Steatosis drives monocyte-derived macrophage accumulation in human metabolic dysfunction-associated fatty liver disease

scientific article published in November 2023

TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy

scientific article published on 01 November 2019

TFEB and trehalose drive the macrophage autophagy-lysosome system to protect against atherosclerosis

scientific article

TFEB drives PGC-1α expression in adipocytes to protect against diet-induced metabolic dysfunction

scientific article published on 05 November 2019

TFEB is a master regulator of tumor-associated macrophages in breast cancer

scientific article published on 01 June 2020

TFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehalose

scientific article published on 06 August 2018

TMEM135 links peroxisomes to the regulation of brown fat mitochondrial fission and energy homeostasis

scientific article published on 29 September 2023

Target acquired: Selective autophagy in cardiometabolic disease

scientific article published on 28 February 2017

The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.

scientific article

Transcriptional factor EB regulates macrophage polarization in the tumor microenvironment

scientific article published on 20 April 2017

Ursolic acid enhances macrophage autophagy and attenuates atherogenesis

scientific article published on 10 April 2016

metGWAS 1.0: an R workflow for network-driven over-representation analysis between independent metabolomic and meta-genome-wide association studies

scientific article published on 23 August 2023

p53 is required for chloroquine-induced atheroprotection but not insulin sensitization.

scientific article

p62/SQSTM1 and Selective Autophagy in Cardiometabolic Diseases

scientific article published on 11 February 2019

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