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List of works by Alan McIntyre

Activating mutations and/or expression levels of tyrosine kinase receptors GRB7, RAS, and BRAF in testicular germ cell tumors

scientific article

Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism

scientific article published on 18 March 2019

Altered glutamine metabolism in breast cancer; subtype dependencies and alternative adaptations

scientific article published on 3 August 2017

Amplification and overexpression of the KIT gene is associated with progression in the seminoma subtype of testicular germ cell tumors of adolescents and adults

scientific article

Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapy

scientific article

Association between Large-scale Genomic Homozygosity without Chromosomal Loss and Nonseminomatous Germ Cell Tumor Development

article

Carbonic Anhydrase Activity Monitored In Vivo by Hyperpolarized 13C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors

scientific article

Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition

scientific article

Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy

scientific article

Clinical and biological significance of CXCL12 and CXCR4 expression in adult testes and germ cell tumours of adults and adolescents.

scientific article published on January 2009

Controlling distinct signaling states in cultured cancer cells provides a new platform for drug discovery

scientific article published on 30 May 2019

Defining minimum genomic regions of imbalance involved in testicular germ cell tumors of adolescents and adults through genome wide microarray analysis of cDNA clones

scientific article published on 01 December 2004

Disrupting Hypoxia-Induced Bicarbonate Transport Acidifies Tumor Cells and Suppresses Tumor Growth.

scientific article published on 17 May 2016

Fatty acid-binding protein 4, a point of convergence for angiogenic and metabolic signaling pathways in endothelial cells.

scientific article

Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia.

scientific article published on 29 June 2016

Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene

scientific article

Genomic copy number and expression patterns in testicular germ cell tumours.

scientific article published on 4 December 2007

Genomic gain and over expression of CCL2 correlate with vascular invasion in stage I non-seminomatous testicular germ-cell tumours.

scientific article

Glucose utilization via glycogen phosphorylase sustains proliferation and prevents premature senescence in cancer cells

scientific article published on 21 November 2012

Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer.

scientific article published on 31 May 2019

IGF1R signalling in testicular germ cell tumour cells impacts on cell survival and acquired cisplatin resistance

scientific article published on 21 November 2017

Intratumour heterogeneity in microRNAs expression regulates glioblastoma metabolism

scientific article published on 05 August 2021

KIT and RAS signalling pathways in testicular germ cell tumours: new data and a review of the literature.

scientific article

Metabolic and hypoxic adaptation to anti-angiogenic therapy: a target for induced essentiality

scientific article

Methods: Using Three-Dimensional Culture (Spheroids) as an In Vitro Model of Tumour Hypoxia

scientific article published on January 2016

MicroRNA Post-transcriptional Regulation of the NLRP3 Inflammasome in Immunopathologies

scientific article published on 01 May 2019

MicroRNA Regulation of Glycolytic Metabolism in Glioblastoma.

scientific article

Minimum regions of genomic imbalance in stage I testicular embryonal carcinoma and association of 22q loss with relapse.

scientific article

Proline-hydroxylated hypoxia-inducible factor 1α (HIF-1α) upregulation in human tumours

scientific article

Publisher Correction: Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS

scientific article published on 06 November 2020

Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS

scientific article published on 21 September 2020

Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation.

scientific article published on 14 June 2011

Stem cell factor as a novel diagnostic marker for early malignant germ cells.

scientific article

The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer

scientific article published on 13 June 2016

The Role of Oxygen in Avascular Tumor Growth

scientific article

The Role of pH Regulation in Cancer Progression.

scientific article

The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions

scientific article

The tumour hypoxia induced non-coding transcriptome.

scientific article

Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer

scientific article published on 03 February 2021

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