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List of works by Saveria Aquila

17β-estradiol enhances α(5) integrin subunit gene expression through ERα-Sp1 interaction and reduces cell motility and invasion of ERα-positive breast cancer cells

scientific article published on 6 January 2010

A new role of anandamide in human sperm: focus on metabolism.

scientific article published in October 2009

A novel functional interplay between Progesterone Receptor-B and PTEN, via AKT, modulates autophagy in breast cancer cells.

scientific article

Adnexal Gland Secretion Markers in Unexplained Asthenozoospermia

scientific article published on 01 January 1994

Androgens inhibit aromatase expression through DAX-1: insights into the molecular link between hormone balance and Leydig cancer development

scientific article

Antiestrogens upregulate estrogen receptor beta expression and inhibit adrenocortical H295R cell proliferation.

scientific article published on October 2005

Autocrine regulation of insulin secretion in human ejaculated spermatozoa.

scientific article published on 18 November 2004

Bergapten drives autophagy through the up-regulation of PTEN expression in breast cancer cells

scientific article published on 7 July 2015

Bergapten induces ER depletion in breast cancer cells through SMAD4-mediated ubiquitination.

scientific article published on 9 October 2012

Bergapten induces metabolic reprogramming in breast cancer cells

scientific article published on 8 October 2015

Bone mineral density is inversely related to parathyroid hormone in adolescent girls

scientific article published on 01 March 2001

Breast cancer cell survival signal is affected by bergapten combined with an ultraviolet irradiation

scientific article published on 4 April 2010

Conventional progesterone receptors (PR) B and PRA are expressed in human spermatozoa and may be involved in the pathophysiology of varicocoele: a role for progesterone in metabolism

scientific article published on October 14, 2010

Cytochrome P450 aromatase expression in human seminoma.

scientific article

Cytochrome P450arom, androgen and estrogen receptors in pig sperm

scientific article published on 6 June 2007

Detection of estrogen receptors ER-alpha and ER-beta in human ejaculated immature spermatozoa with excess residual cytoplasm

scientific article published on 17 July 2006

Effects of castration on androstenedione, testosterone and dihydrotestosterone plasma levels in adult male rats

scientific article published on 01 January 1986

Epigallocatechin gallate affects survival and metabolism of human sperm.

scientific article published on 13 September 2012

Estrogen receptor (ER)alpha and ER beta are both expressed in human ejaculated spermatozoa: evidence of their direct interaction with phosphatidylinositol-3-OH kinase/Akt pathway.

scientific article

Estrogen receptor beta (ERβ) produces autophagy and necroptosis in human seminoma cell line through the binding of the Sp1 on the phosphatase and tensin homolog deleted from chromosome 10 (PTEN) promoter gene.

scientific article

Evidence that low doses of Taxol enhance the functional transactivatory properties of p53 on p21 waf promoter in MCF-7 breast cancer cells

scientific article

Expression and Subcellular Localization of Retinoic Acid Receptor-α (RARα) in Healthy and Varicocele Human Spermatozoa: Its Possible Regulatory Role in Capacitation and Survival.

scientific article published in May 2015

Expression of cyclooxygenase‐1 (COX‐1) and COX‐2 in human male gametes from normal patients, and those with varicocele and diabetes: a potential molecular marker for diagnosing male infertility disorders

scientific article published on July 2, 2012

Expression profile and subcellular localization of GAPDH in the smooth muscle cells of human atherosclerotic plaque: an immunohistochemical and ultrastructural study with biological therapeutic perspectives

scientific article published on 23 May 2014

Follow-up study of thyroid function in polytransfused thalassemic patients

scientific article published on 01 February 1995

Gper and ESRs are expressed in rat round spermatids and mediate oestrogen-dependent rapid pathways modulating expression of cyclin B1 and Bax.

scientific article

HIF-1α and VEGF: Immunohistochemical Profile and Possible Function in Human Aortic Valve Stenosis

scientific article published on 8 January 2015

Human Sperm Anatomy: Different Expression and Localization of Phosphatidylinositol 3-Kinase in Normal and Varicocele Human Spermatozoa

scientific article published on 01 May 2013

Human ejaculated spermatozoa contain active P450 aromatase.

scientific article published in July 2002

Human male gamete endocrinology: 1alpha, 25-dihydroxyvitamin D3 (1,25(OH)2D3) regulates different aspects of human sperm biology and metabolism.

scientific article

Human sperm anatomy and endocrinology in varicocele: role of androgen receptor

scientific article published on 08 April 2014

Human sperm anatomy: ultrastructural localization of the cannabinoid1 receptor and a potential role of anandamide in sperm survival and acrosome reaction.

scientific article published in February 2010

Human sperm express a functional androgen receptor: effects on PI3K/AKT pathway.

scientific article published on 26 July 2007

Human sperm liver receptor homolog-1 (LRH-1) acts as a downstream target of the estrogen signaling pathway

scientific article published on 4 August 2015

Human sperm molecular anatomy: the enzyme 5α-reductase (SRD5A) is present in the sperm and may be involved in the varicocele-related infertility

scientific article

Human sperm physiology: estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) influence sperm metabolism and may be involved in the pathophysiology of varicocele-associated male infertility

scientific article published on 01 December 2011

Identification of G protein-coupled estrogen receptor in human and pig spermatozoa.

scientific article published on 2 April 2014

In vitro mechanism for downregulation of ER-α expression by epigallocatechin gallate in ER+/PR+ human breast cancer cells

scientific article

Influence of all-trans retinoic acid on sperm metabolism and oxidative stress: Its involvement in the physiopathology of varicocele-associated male infertility

scientific article published on 26 June 2018

Insulin affects sperm capacity in pig through nitric oxide

scientific article published on 03 June 2013

Insulin and IR-beta in pig spermatozoa: a role of the hormone in the acquisition of fertilizing ability.

scientific article

Internal mammary artery atherosclerosis: an ultrastructural study of two cases.

scientific article published on 27 January 2014

Leptin and its receptor are expressed in the testis and in the epididymis of young and adult pigs

scientific article published in May 2009

Leptin and leptin receptor in pig spermatozoa: evidence of their involvement in sperm capacitation and survival

scientific article published on 26 March 2008

Leptin secretion by human ejaculated spermatozoa

scientific article published on 8 June 2005

Low calcium intake is associated with decreased adrenal androgens and reduced bone age in premenarcheal girls in the last pubertal stages.

scientific article published in January 2004

Low seminal zinc bound to high molecular weight proteins in asthenozoospermic patients: evidence of increased sperm zinc content in oligoasthenozoospermic patients.

scientific article

Matrix Metalloproteinase-9 Expression in Calcified Human Aortic Valves: A Histopathologic, Immunohistochemical, and Ultrastructural Study.

scientific article published on 11 November 2014

Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production.

scientific article

Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth

scientific article

Nitric oxide involvement in the acrosome reaction triggered by leptin in pig sperm

scientific article published on 4 October 2011

Omega-3 PUFA ethanolamides DHEA and EPEA induce autophagy through PPARγ activation in MCF-7 breast cancer cells

scientific article published in June 2013

Peroxisome proliferator-activated receptor (PPAR)gamma is expressed by human spermatozoa: its potential role on the sperm physiology

scientific article published on 01 December 2006

Peroxisome proliferator-activated receptor gamma activates fas ligand gene promoter inducing apoptosis in human breast cancer cells

scientific article

Peroxisome proliferator-activated receptor gamma inhibits follicular and anaplastic thyroid carcinoma cells growth by upregulating p21Cip1/WAF1 gene in a Sp1-dependent manner.

scientific article

Peroxisome proliferator-activated receptor-gamma activates p53 gene promoter binding to the nuclear factor-kappaB sequence in human MCF7 breast cancer cells

scientific article

Progesterone through progesterone receptors affects survival and metabolism of pig sperm.

scientific article published on 23 September 2012

Red wine consumption may affect sperm biology: the effects of different concentrations of the phytoestrogen myricetin on human male gamete function

scientific article published on 30 January 2013

Rimonabant (SR141716) induces metabolism and acquisition of fertilizing ability in human sperm

scientific article

Sperm metabolism in pigs: a role for peroxisome proliferator-activated receptor gamma (PPAR )

scientific article published on 15 November 2012

Steroid receptors and their ligands: effects on male gamete functions.

scientific article

T3 enhances thyroid cancer cell proliferation through TRβ1/Oct-1-mediated cyclin D1 activation

scientific article published on 9 October 2013

The effect of dietary calcium intake on bone mineral density in healthy adolescent girls and young women in southern Italy

scientific article published on 01 June 1999

The estrogen receptor α is the key regulator of the bifunctional role of FoxO3a transcription factor in breast cancer motility and invasiveness

scientific article published on 17 September 2013

The mitochondrial citrate carrier (CIC) is present and regulates insulin secretion by human male gamete.

scientific article published on 21 February 2012

The nuclear localization signal is required for nuclear GPER translocation and function in breast Cancer-Associated Fibroblasts (CAFs).

scientific article published on 5 June 2013

The role of oxidative stress and autophagy in atherosclerosis

scientific article

Towards a physiological role for cytochrome P450 aromatase in ejaculated human sperm.

scientific article published in August 2003

Ultrastructure of popliteal vein aneurysm.

scientific article published on 9 June 2011