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List of works by Brett T Spear

Activation of hepatic NF-kappaB by phenobarbital in rats

scientific article published on 01 December 1996

Activation of nuclear factor-kappaB by the peroxisome proliferator ciprofibrate in H4IIEC3 rat hepatoma cells and its inhibition by the antioxidants N-acetylcysteine and vitamin E

scientific article published on 01 February 2000

Alpha-fetoprotein related gene (ARG): a new member of the albumin gene family that is no longer functional in primates

scientific article

Carbohydrate differences in HLA-DR molecules synthesized by alveolar macrophages and blood monocytes

scientific article published on 01 June 1987

Cell proliferation and apoptosis are altered in mice deficient in the NF-kappaB p50 subunit after treatment with the peroxisome proliferator ciprofibrate.

scientific article published on 25 July 2003

Characterization of the ETnII-alpha endogenous retroviral element in the BALB/cJ Zhx2 ( Afr1 ) allele

scientific article published on 08 December 2007

Dietary antioxidants in the prevention of hepatocarcinogenesis: a review.

scientific article published on July 2010

Differential activation of hepatic NF-kappaB in rats and hamsters by the peroxisome proliferators Wy-14,643, gemfibrozil, and dibutyl phthalate.

scientific article published on July 2001

Effect of 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) on hepatocyte proliferation and apoptosis in mice deficient in the p50 subunit of the transcription factor NF-kappaB.

scientific article

Effect of antioxidant phytochemicals on the hepatic tumor promoting activity of 3,3',4,4'-tetrachlorobiphenyl (PCB-77)

scientific article published on 30 August 2008

Effect of dietary selenium on the promotion of hepatocarcinogenesis by 3,3', 4,4'-tetrachlorobiphenyl and 2,2', 4,4', 5,5'-hexachlorobiphenyl.

scientific article

Effect of phenobarbital on hepatic cell proliferation and apoptosis in mice deficient in the p50 subunit of NF-kappaB

scientific article published on 26 September 2007

Effect of the peroxisome proliferator ciprofibrate on lipid peroxidation and 8-hydroxydeoxyguanosine formation in transgenic mice with elevated hepatic catalase activity

scientific article published on 01 June 1998

Effect of vitamin E on hepatic cell proliferation and apoptosis in mice deficient in the p50 subunit of NF-κB after treatment with phenobarbital.

scientific article

Effects of cigarette smoke on the activation of oxidative stress-related transcription factors in female A/J mouse lung.

scientific article

Effects of peroxisome proliferators on antioxidant enzymes and antioxidant vitamins in rats and hamsters.

scientific article published in April 2001

Effects of vitamin E on the NF-kappaB pathway in rats treated with the peroxisome proliferator, ciprofibrate

scientific article

Endogenous and transfected mouse alpha-fetoprotein genes in undifferentiated F9 cells are activated in transient heterokaryons.

scientific article published on January 1995

Evolutionary Analysis of the Zinc Finger and Homeoboxes Family of Proteins Identifies Multiple Conserved Domains and a Common Early Chordate Ancestor

scientific article published on 01 March 2020

Expression of the hydrogen peroxide-generating enzyme fatty acyl CoA oxidase activates NF-kappaB.

scientific article published on February 2000

Hereditary persistence of alpha-fetoprotein and H19 expression in liver of BALB/cJ mice is due to a retrovirus insertion in the Zhx2 gene.

scientific article

Increased liver-specific catalase activity in transgenic mice

scientific article published on 01 August 1996

Increased liver-specific expression of catalase in transgenic mice

scientific article published on 01 December 1996

Inhibition of hepatocarcinogenesis by the deletion of the p50 subunit of NF-kappaB in mice administered the peroxisome proliferator Wy-14,643.

scientific article published on 24 January 2006

Insertional mutation of the motor endplate disease (med) locus on mouse chromosome 15.

scientific article published in March 1995

Liver size and lipid content differences between BALB/c and BALB/cJ mice on a high-fat diet are due, in part, to Zhx2

scientific article published on 18 July 2019

Mutation of a new sodium channel gene, Scn8a, in the mouse mutant ‘motor endplate disease’

scientific article (publication date: August 1995)

Normal intestinal epithelial cell differentiation in the absence of p21 and p27: new insights from old knock-out mice

scientific article published on 21 May 2008

PCB 153, a non-dioxin-like tumor promoter, selects for beta-catenin (Catnb)-mutated mouse liver tumors

scientific article published on 16 June 2006

PDGF-A promoter and enhancer elements provide efficient and selective antineoplastic gene therapy in multiple cancer types

scientific article

PKI-587 and sorafenib alone and in combination on inhibition of liver cancer stem cell proliferation

scientific article

Pericentral activity of alpha-fetoprotein enhancer 3 and glutamine synthetase upstream enhancer in the adult liver are regulated by β-catenin in mice.

scientific article published on November 2012

Peroxisome proliferators do not activate the transcription factors AP-1, early growth response-1, or heat shock factors 1 and 2 in rats or hamsters.

scientific article

Quantitative trait locus mapping and identification of Zhx2 as a novel regulator of plasma lipid metabolism.

scientific article

Regulation of cell proliferation, apoptosis, and transcription factor activities during the promotion of liver carcinogenesis by polychlorinated biphenyls.

scientific article published in March 2002

Role of the p50 subunit of NF-kappaB in vitamin E-induced changes in mice treated with the peroxisome proliferator, ciprofibrate

scientific article published on 05 February 2008

Systemic Par-4 inhibits non-autochthonous tumor growth.

scientific article published on 15 July 2011

Targeting the Wnt/β-catenin signaling pathway in liver cancer stem cells and hepatocellular carcinoma cell lines with FH535

scientific article

The Role of NF-kappaB in PPARalpha-Mediated Hepatocarcinogenesis.

scientific article published on January 2008

The alpha-fetoprotein promoter is the target of Afr1-mediated postnatal repression

scientific journal article

The mouse alpha-albumin (afamin) promoter is differentially regulated by hepatocyte nuclear factor 1α and hepatocyte nuclear factor 1β

scientific article published on October 27, 2010

The neuronal voltage-gated sodium channel, Scn8a, is essential for postnatal maturation of spinal, but not oculomotor, motor units

scientific article published on 01 June 1996

The oncofetal gene glypican 3 is regulated in the postnatal liver by zinc fingers and homeoboxes 2 and in the regenerating liver by alpha-fetoprotein regulator 2.

scientific article published on November 2007

Transcriptional control in the mammalian liver: liver development, perinatal repression, and zonal gene regulation.

scientific article published on December 2006

Zhx2 and Zbtb20: novel regulators of postnatal alpha-fetoprotein repression and their potential role in gene reactivation during liver cancer.

scientific article published on 7 January 2011

Zinc fingers and homeoboxes 2 inhibits hepatocellular carcinoma cell proliferation and represses expression of Cyclins A and E.

scientific article