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List of works by Cinta Bladé

A trimer plus a dimer-gallate reproduce the bioactivity described for an extract of grape seed procyanidins

article by Gemma Montagut et al published September 2009 in Food Chemistry

Acute administration of grape seed proanthocyanidin extract modulates energetic metabolism in skeletal muscle and BAT mitochondria

scientific article published on 14 March 2011

Alpha 2-adrenergic blockade prevents hyperglycemia and hepatic glutathione depletion in nickel-injected rats

scientific article published on 01 July 1993

Alterations in rat mineral metabolism induced by acute ammonium acetate infusion

scientific article published on 01 January 1989

Ammonium uptake and urea production in hepatocytes from lean and obese Zucker rats

scientific article published on 01 October 1999

Antioxidant effects of a grapeseed procyanidin extract and oleoyl-estrone in obese Zucker rats

scientific article published on 15 April 2011

Bioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models

scientific article published on 14 December 2009

Bioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models – CORRIGENDUM

scholarly article published in British Journal of Nutrition

Chronic administration of proanthocyanidins or docosahexaenoic acid reverses the increase of miR-33a and miR-122 in dyslipidemic obese rats.

scientific article

Chronic consumption of dietary proanthocyanidins modulates peripheral clocks in healthy and obese rats.

scientific article published on 13 October 2014

Chronic dietary supplementation of proanthocyanidins corrects the mitochondrial dysfunction of brown adipose tissue caused by diet-induced obesity in Wistar rats

scientific article published on 28 June 2011

Chronic intake of proanthocyanidins and docosahexaenoic acid improves skeletal muscle oxidative capacity in diet-obese rats

scientific article published on 5 June 2014

Chronic supplementation of proanthocyanidins reduces postprandial lipemia and liver miR-33a and miR-122 levels in a dose-dependent manner in healthy rats.

scientific article

Combination of grape seed proanthocyanidin extract and docosahexaenoic acid-rich oil increases the hepatic detoxification by GST mediated GSH conjugation in a lipidic postprandial state

scientific article published on 27 May 2014

DHA sensitizes FaO cells to tert-BHP-induced oxidative effects. Protective role of EGCG.

scientific article published on 16 October 2013

Detection and characterization of silver nanoparticles and dissolved species of silver in culture medium and cells by AsFlFFF-UV-Vis-ICPMS: application to nanotoxicity tests

scientific article published in March 2014

Dietary catechins and procyanidins modulate zinc homeostasis in human HepG2 cells

scientific article

Dietary proanthocyanidins modulate BMAL1 acetylation, Nampt expression and NAD levels in rat liver

scientific article published on 8 June 2015

Dietary proanthocyanidins modulate melatonin levels in plasma and the expression pattern of clock genes in the hypothalamus of rats

scientific article published on 23 March 2015

Dietary procyanidins enhance transcriptional activity of bile acid-activated FXR in vitro and reduce triglyceridemia in vivo in a FXR-dependent manner.

scientific article

Dietary procyanidins lower triglyceride levels signaling through the nuclear receptor small heterodimer partner.

scientific article

Differential effects of grape-seed derived procyanidins on adipocyte differentiation markers in different in vivo situations

scientific article published on October 2007

Differential modulation of apoptotic processes by proanthocyanidins as a dietary strategy for delaying chronic pathologies.

scientific article published on January 2014

Effects of a grapeseed procyanidin extract (GSPE) on insulin resistance.

scientific article published on 4 December 2009

Effects of copper exposure upon nitrogen metabolism in tissue cultured Vitis vinifera

scientific article published on 01 December 2000

Epigallocatechin gallate counteracts oxidative stress in docosahexaenoxic acid-treated myocytes.

scientific article published on 28 January 2014

Erratum to “Moderate red-wine consumption partially prevents body weight gain in rats fed a hyperlipidic diet” [J Nutr Biochem 17 (2006) 139-142]

scholarly article published in Journal of Nutritional Biochemistry

Exosomes transport trace amounts of (poly)phenols

scientific article published on 18 August 2020

Flavanol metabolites distribute in visceral adipose depots after a long-term intake of grape seed proanthocyanidin extract in rats

scientific article published on 14 March 2013

Glutamine and ammonium handling by anaesthetized rats

article by C. Bladé et al published January 1988 in Archives internationales de physiologie et de biochimie

Grape seed proanthocyanidin extract improves the hepatic glutathione metabolism in obese Zucker rats

scientific article published on 16 December 2013

Grape seed proanthocyanidins correct dyslipidemia associated with a high-fat diet in rats and repress genes controlling lipogenesis and VLDL assembling in liver.

scientific article

Grape seed proanthocyanidins repress the hepatic lipid regulators miR-33 and miR-122 in rats.

scientific article published on 11 September 2012

Grape seed procyanidins improve atherosclerotic risk index and induce liver CYP7A1 and SHP expression in healthy rats

scientific article published on 6 January 2005

Grape seed procyanidins inhibit the expression of metallothione in genes in human HepG2 cells

scientific article published on October 2007

Grape seed procyanidins prevent oxidative injury by modulating the expression of antioxidant enzyme systems.

scientific article published on July 2005

Grape-seed procyanidins act as antiinflammatory agents in endotoxin-stimulated RAW 264.7 macrophages by inhibiting NFkB signaling pathway

scientific article (publication date: 30 May 2007)

Grape-seed procyanidins prevent low-grade inflammation by modulating cytokine expression in rats fed a high-fat diet

scientific article published on 7 July 2008

Human apo A-I and rat transferrin are the principal plasma proteins that bind wine catechins

scientific article published in April 2002

Hypolipidemic effects of proanthocyanidins and their underlying biochemical and molecular mechanisms.

scientific article published on January 2010

Identification of human IKK-2 inhibitors of natural origin (Part II): in Silico prediction of IKK-2 inhibitors in natural extracts with known anti-inflammatory activity

scientific article published on 22 September 2011

Identification of novel human dipeptidyl peptidase-IV inhibitors of natural origin (Part II): in silico prediction in antidiabetic extracts

scientific article

Improvement of mitochondrial function in muscle of genetically obese rats after chronic supplementation with proanthocyanidins

scientific article published on 15 July 2011

In vivo, in vitro, and in silico studies of Cu/Zn-superoxide dismutase regulation by molecules in grape seed procyanidin extract.

scientific article published on May 2009

Inhibitory effects of grape seed procyanidins on foam cell formation in vitro

scientific article published on March 2009

Isoflavone effect on gene expression profile and biomarkers of inflammation.

scientific article published on 5 April 2009

Lipogenesis is decreased by grape seed proanthocyanidins according to liver proteomics of rats fed a high fat diet.

scientific article

Long-term supplementation with a low dose of proanthocyanidins normalized liver miR-33a and miR-122 levels in high-fat diet-induced obese rats.

scientific article published on 28 February 2015

Metabolic fate of glucose on 3T3-L1 adipocytes treated with grape seed-derived procyanidin extract (GSPE). Comparison with the effects of insulin.

scientific article published on July 2005

Metabolomic assessment of the effect of dietary cholesterol in the progressive development of fatty liver disease

scientific article published in May 2010

Metabolomics reveals reduction of metabolic oxidation in women with polycystic ovary syndrome after pioglitazone-flutamide-metformin polytherapy

scientific article

Model for Voluntary Wine and Alcohol Consumption in Rats

scientific article published on 01 August 1997

Moderate red wine consumption protects the rat against oxidation in vivo

scientific article published on 01 January 1999

Moderate red-wine consumption partially prevents body weight gain in rats fed a hyperlipidic diet

scientific article published on 28 July 2005

Modulatory effect of grape-seed procyanidins on local and systemic inflammation in diet-induced obesity rats

scientific article published on 23 July 2010

Nutritional biomarkers and foodomic methodologies for qualitative and quantitative analysis of bioactive ingredients in dietary intervention studies.

scientific article published on 23 August 2011

Oligomers of grape-seed procyanidin extract activate the insulin receptor and key targets of the insulin signaling pathway differently from insulin

scientific article published on 14 May 2009

Optimization of extraction methods for characterization of phenolic compounds in apricot fruit (Prunus armeniaca)

scientific article published on 01 October 2019

Organotypic co-culture system to study plant extract bioactivity on hepatocytes

article

Potential Involvement of Peripheral Leptin/STAT3 Signaling in the Effects of Resveratrol and Its Metabolites on Reducing Body Fat Accumulation

scientific article published on 14 November 2018

Proanthocyanidins Modulate MicroRNA Expression in Human HepG2 Cells ⬇️

scientific article published on October 5, 2011

Proanthocyanidins in health and disease

scientific article

Proanthocyanidins modulate triglyceride secretion by repressing the expression of long chain acyl-CoA synthetases in Caco2 intestinal cells

Procyanidin dimer B1 and trimer C1 impair inflammatory response signalling in human monocytes.

scientific article published on May 2011

Procyanidin effects on adipocyte-related pathologies.

scientific article published on January 2006

Procyanidins protect Fao cells against hydrogen peroxide-induced oxidative stress

scientific article published on August 2002

Protein-ligand Docking: A Review of Recent Advances and Future Perspectives

Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells.

scientific article published on 27 October 2013

Roles of proanthocyanidin rich extracts in obesity.

scientific article

Seasonal consumption of polyphenol-rich fruits affects the hypothalamic leptin signaling system in a photoperiod-dependent mode

scientific article published in Scientific Reports

Splanchnic amino acid pattern in genetic and dietary obesity in the rat.

scientific article published on October 1994

Tetramethylated Dimeric Procyanidins Are Detected in Rat Plasma and Liver Early after Oral Administration of Synthetic Oligomeric Procyanidins

scientific article published on 01 April 2006

The Disruption of Liver Metabolic Circadian Rhythms by a Cafeteria Diet Is Sex-Dependent in Fischer 344 Rats

scientific article published on 14 April 2020

The lipid-lowering effect of dietary proanthocyanidins in rats involves both chylomicron-rich and VLDL-rich fractions

scientific article published on 20 October 2011

miRNAs, polyphenols, and chronic disease ⬇️

scientific article published on November 20, 2012

microRNAs as new targets of dietary polyphenols

scientific article published on January 2014

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