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List of works by Pietro Genovese

An unbiased genome-wide analysis of zinc-finger nuclease specificity

scientific article

CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma

scientific article published on 9 September 2013

Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells

article

Cytokine-induced killer cells engineered with exogenous T-cell receptors directed against melanoma antigens: enhanced efficacy of effector cells endowed with a double mechanism of tumor recognition

scientific article

Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer

scientific article

Efficient gene editing of human long-term hematopoietic stem cells validated by clonal tracking

scientific article published on 29 June 2020

Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

scientific article (publication date: 28 October 2007)

Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk

scientific article

Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper-IgM syndrome

scientific article published on 21 January 2021

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease.

scientific article

Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response

article

Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1.

scientific article published in October 2017

Site-specific integration and tailoring of cassette design for sustainable gene transfer.

scientific article published on 21 August 2011

Targeted gene therapy and cell reprogramming in Fanconi anemia

scientific article published on 23 May 2014

Targeted genome editing in human repopulating haematopoietic stem cells

scientific article published on 28 May 2014

Therapeutic gene editing in CD34+ hematopoietic progenitors from Fanconi anemia patients.

scientific article published on 12 September 2017

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