List of works - Wayne W Poon

3-Hexaprenyl-4-hydroxybenzoic acid forms a predominant intermediate pool in ubiquinone biosynthesis in Saccharomyces cerevisiae

scientific article

A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy

scientific article

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

scientific article

AD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56-kDa assembly

scientific article

Altered brain energetics induces mitochondrial fission arrest in Alzheimer's Disease

scientific article

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex

scientific article

Apolipoprotein E/Amyloid-β Complex Accumulates in Alzheimer Disease Cortical Synapses via Apolipoprotein E Receptors and Is Enhanced by APOE4

scientific article published on 17 May 2019

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Beta-amyloid deposition and tau phosphorylation in clinically characterized aged cats.

scientific article published in May 2005

Blood-brain barrier dysfunction and cerebral small vessel disease (arteriolosclerosis) in brains of older people.

scientific article

Caspase-Cleaved Tau Co-Localizes with Early Tangle Markers in the Human Vascular Dementia Brain

scientific article published on 10 July 2015

Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology

article

Caspase-mediated degeneration in Alzheimer's disease

scientific article published in August 2004

Cerebrovascular pathology in Down syndrome and Alzheimer disease.

scientific article

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

scientific article

Complementation of coq3 mutant yeast by mitochondrial targeting of the Escherichia coli UbiG polypeptide: evidence that UbiG catalyzes both O-methylation steps in ubiquinone biosynthesis.

scientific article

Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q.

scientific article

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

scientific article

Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid

scientific article published on 9 April 2008

Extensive p-tau pathology and SDS-stable p-tau oligomers in Alzheimer's cortical synapses

scientific article

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

HuCNS-SC Human NSCs Fail to Differentiate, Form Ectopic Clusters, and Provide No Cognitive Benefits in a Transgenic Model of Alzheimer's Disease.

scientific article published on February 2017

Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss

scientific article

Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis

scientific article

Immunolocalization of an amino-terminal fragment of apolipoprotein E in the Pick's disease brain

scientific article

Increased tauopathy drives microglia-mediated clearance of beta-amyloid.

scientific article published on 23 June 2016

Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes

scientific article published on 12 March 2021

Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques

scientific article

Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples

scientific article published on 4 January 2013

Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.

scholarly article

Neural stem cells rescue deficits in Alzheimer's transgenic mice

Neutrophin-trafficking deficits are mediated by impaired ubiquitin recycling in Alzheimer's disease

scholarly article by Wayne W Poon et al published July 2012 in Alzheimer's and Dementia

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

scientific article

Pre-synaptic C-terminal truncated tau is released from cortical synapses in Alzheimer's disease

scientific article

Preferential accumulation of amyloid-beta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer's disease cortex

scientific article published on 3 September 2011

Quantitative analysis of axonal transport by using compartmentalized and surface micropatterned culture of neurons.

scientific article

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

scientific article

Sensitivity to treatment with polyunsaturated fatty acids is a general characteristic of the ubiquinone-deficient yeast coq mutants.

scientific article

Super-resolution imaging of subcortical white matter using stochastic optical reconstruction microscopy (STORM) and super-resolution optical fluctuation imaging (SOFI).

scientific article published on 11 July 2017

Synaptic Amyloid-β Oligomers Precede p-Tau and Differentiate High Pathology Control Cases

scientific article

Tau Spread, Apolipoprotein E, Inflammation, and More: Rapidly Evolving Basic Science in Alzheimer Disease

scientific article

The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function

scientific article published on 16 February 2016

The biosynthesis of ubiquinone: Synthesis and enzymatic modification of biosynthetic precursors

The role of caspase cleavage of tau in Alzheimer disease neuropathology

scientific article

iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases.

scientific article

β-Amyloid (Aβ) oligomers impair brain-derived neurotrophic factor retrograde trafficking by down-regulating ubiquitin C-terminal hydrolase, UCH-L1.

scientific article published on 18 April 2013

β-Amyloid impairs axonal BDNF retrograde trafficking

scientific article

List of works by Wayne W Poon

3-Hexaprenyl-4-hydroxybenzoic acid forms a predominant intermediate pool in ubiquinone biosynthesis in Saccharomyces cerevisiae

A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

AD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56-kDa assembly

Altered brain energetics induces mitochondrial fission arrest in Alzheimer's Disease

Analysis of shared heritability in common disorders of the brain

Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex

Apolipoprotein E/Amyloid-β Complex Accumulates in Alzheimer Disease Cortical Synapses via Apolipoprotein E Receptors and Is Enhanced by APOE4

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Beta-amyloid deposition and tau phosphorylation in clinically characterized aged cats.

Blood-brain barrier dysfunction and cerebral small vessel disease (arteriolosclerosis) in brains of older people.

Caspase-Cleaved Tau Co-Localizes with Early Tangle Markers in the Human Vascular Dementia Brain

Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology

Caspase-mediated degeneration in Alzheimer's disease

Cerebrovascular pathology in Down syndrome and Alzheimer disease.

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

Complementation of coq3 mutant yeast by mitochondrial targeting of the Escherichia coli UbiG polypeptide: evidence that UbiG catalyzes both O-methylation steps in ubiquinone biosynthesis.

Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q.

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid

Extensive p-tau pathology and SDS-stable p-tau oligomers in Alzheimer's cortical synapses

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

HuCNS-SC Human NSCs Fail to Differentiate, Form Ectopic Clusters, and Provide No Cognitive Benefits in a Transgenic Model of Alzheimer's Disease.

Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss

Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis

Immunolocalization of an amino-terminal fragment of apolipoprotein E in the Pick's disease brain

Increased tauopathy drives microglia-mediated clearance of beta-amyloid.

Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes

Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques

Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples

Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.

Neural stem cells rescue deficits in Alzheimer's transgenic mice

Neutrophin-trafficking deficits are mediated by impaired ubiquitin recycling in Alzheimer's disease

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

Pre-synaptic C-terminal truncated tau is released from cortical synapses in Alzheimer's disease

Preferential accumulation of amyloid-beta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer's disease cortex

Quantitative analysis of axonal transport by using compartmentalized and surface micropatterned culture of neurons.

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

Sensitivity to treatment with polyunsaturated fatty acids is a general characteristic of the ubiquinone-deficient yeast coq mutants.

Super-resolution imaging of subcortical white matter using stochastic optical reconstruction microscopy (STORM) and super-resolution optical fluctuation imaging (SOFI).

Synaptic Amyloid-β Oligomers Precede p-Tau and Differentiate High Pathology Control Cases

Tau Spread, Apolipoprotein E, Inflammation, and More: Rapidly Evolving Basic Science in Alzheimer Disease

The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function

The biosynthesis of ubiquinone: Synthesis and enzymatic modification of biosynthetic precursors

The role of caspase cleavage of tau in Alzheimer disease neuropathology

iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases.

β-Amyloid (Aβ) oligomers impair brain-derived neurotrophic factor retrograde trafficking by down-regulating ubiquitin C-terminal hydrolase, UCH-L1.

β-Amyloid impairs axonal BDNF retrograde trafficking