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List of works by Dominique Mengin-Lecreulx

5'-Methylene-triazole-substituted-aminoribosyl uridines as MraY inhibitors: synthesis, biological evaluation and molecular modeling.

scientific article

A Drosophila pattern recognition receptor contains a peptidoglycan docking groove and unusual L,D-carboxypeptidase activity

scientific article

A MurG assay which utilises a synthetic analogue of lipid I.

scientific article published in February 2003

A peptidoglycan fragment triggers β-lactam resistance in Bacillus licheniformis

scientific article

Active site mapping of MraY, a member of the polyprenyl-phosphate N-acetylhexosamine 1-phosphate transferase superfamily, catalyzing the first membrane step of peptidoglycan biosynthesis

scientific article published on 2 August 2008

An efflux transporter PbrA and a phosphatase PbrB cooperate in a lead-resistance mechanism in bacteria

scholarly article by Anu Hynninen et al published October 2009 in Molecular Microbiology

Antibacterial and hemolytic activities of linenscin OC2, a hydrophobic substance produced by Brevibacterium linens OC2

scientific article published on 01 August 1997

BcrC from Bacillus subtilis acts as an undecaprenyl pyrophosphate phosphatase in bacitracin resistance.

scientific article

Biochemical characterisation of the chlamydial MurF ligase, and possible sequence of the chlamydial peptidoglycan pentapeptide stem

scientific article published on 10 January 2012

Biochemical characterization and physiological properties of Escherichia coli UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase

scientific article published on 23 March 2007

Biochemical characterization of MurF from Streptococcus pneumoniae and the identification of a new MurF inhibitor through ligand-based virtual screening

scientific article published on January 1, 2013

Catalytic mechanism of MraY and WecA, two paralogues of the polyprenyl-phosphate N-acetylhexosamine 1-phosphate transferase superfamily

scientific article published on 13 June 2016

Characterization and chromosomal organization of the murD-murC-ftsQ region of Corynebacterium glutamicum ATCC 13869.

scientific article published in April 2004

Characterization of colicin M and its orthologs targeting bacterial cell wall peptidoglycan biosynthesis

scientific article published on 20 March 2012

Colicin M exerts its bacteriolytic effect via enzymatic degradation of undecaprenyl phosphate-linked peptidoglycan precursors

scientific article published on 15 June 2006

Colicin M hydrolyses branched lipids II from Gram-positive bacteria.

scientific article

Colicin M, a peptidoglycan lipid-II-degrading enzyme: potential use for antibacterial means?

scientific article published on December 2012

Contribution of the Pmra promoter to expression of genes in the Escherichia coli mra cluster of cell envelope biosynthesis and cell division genes.

scientific article

Deciphering the catalytic domain of colicin M, a peptidoglycan lipid II-degrading enzyme

scientific article published on 16 February 2010

Deciphering the metabolism of undecaprenyl-phosphate: the bacterial cell-wall unit carrier at the membrane frontier

scientific article

Diaminopimelic Acid Amidation in Corynebacteriales: NEW INSIGHTS INTO THE ROLE OF LtsA IN PEPTIDOGLYCAN MODIFICATION

scientific article published on 6 April 2015

Drosophila immunity: analysis of PGRP-SB1 expression, enzymatic activity and function

scientific article

Dual regulation of activity and intracellular localization of the PASTA kinase PrkC during Bacillus subtilis growth

scientific article

Efficient access to peptidyl-RNA conjugates for picomolar inhibition of non-ribosomal FemX(Wv) aminoacyl transferase

scientific article published on 29 November 2012

Electrophilic RNA for Peptidyl-RNA Synthesis and Site-Specific Cross-Linking with tRNA-Binding Enzymes.

scientific article published on 26 September 2016

Evidence of a functional requirement for a carbamoylated lysine residue in MurD, MurE and MurF synthetases as established by chemical rescue experiments ⬇️

scientific article published on November 1, 2001

Factors essential for L,D-transpeptidase-mediated peptidoglycan cross-linking and β-lactam resistance in Escherichia coli

scientific article published on 21 October 2016

Fluorescence detection-based functional assay for high-throughput screening for MraY.

scientific article

Functional and Structural Characterization of PaeM, a Colicin M-like Bacteriocin Produced by Pseudomonas aeruginosa

scientific article

Functional and biochemical analysis of Chlamydia trachomatis MurC, an enzyme displaying UDP-N-acetylmuramate:amino acid ligase activity

scientific article

Functional and biochemical analysis of the Chlamydia trachomatis ligase MurE.

scientific article published on 09 October 2009

Glycosyl Transferase Activity of theEscherichia coliPenicillin-Binding Protein 1b: Specificity Profile for the Substrate†

scientific article published in 2006

Human- and plant-pathogenic Pseudomonas species produce bacteriocins exhibiting colicin M-like hydrolase activity towards peptidoglycan precursors

scientific article

HupA, the main undecaprenyl pyrophosphate and phosphatidylglycerol phosphate phosphatase in Helicobacter pylori is essential for colonization of the stomach

scientific article published on 05 September 2019

Identification and Partial Characterization of a Novel UDP-N-Acetylenolpyruvoylglucosamine Reductase/UDP-N-Acetylmuramate:l-Alanine Ligase Fusion Enzyme from Verrucomicrobium spinosum DSM 4136(T).

scientific article published on 23 March 2016

Identification of multiple genes encoding membrane proteins with undecaprenyl pyrophosphate phosphatase (UppP) activity in Escherichia coli

scientific article

Identification of the L,D-transpeptidases responsible for attachment of the Braun lipoprotein to Escherichia coli peptidoglycan

scientific article published on 16 March 2007

Identification of the UDP-MurNAc-pentapeptide:L-alanine ligase for synthesis of branched peptidoglycan precursors in Enterococcus faecalis.

scientific article

Identification of the critical residues involved in peptidoglycan detection by Nod1.

scientific article

Identification of the glmU gene encoding N-acetylglucosamine-1-phosphate uridyltransferase in Escherichia coli.

scientific article

Identification of the mpl gene encoding UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase in Escherichia coli and its role in recycling of cell wall peptidoglycan.

scientific article published on September 1996

Impact of FiuA Outer Membrane Receptor Polymorphism on the Resistance of Pseudomonas aeruginosa toward Peptidoglycan Lipid II-Targeting PaeM Pyocins

scientific article published on 10 June 2019

In Vitro and In Vivo Analysis of the Gram-Negative Bacteria-Derived Riboflavin Precursor Derivatives Activating Mouse MAIT Cells

scientific article published on 13 April 2015

Inhibition of peptidoglycan biosynthesis in Bacillus megaterium by daptomycin.

scientific article

Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM

scientific article published on 22 January 2019

Insights into Substrate Specificity of NlpC/P60 Cell Wall Hydrolases Containing Bacterial SH3 Domains

scientific article published on 15 September 2015

Invariant Amino Acids in the Mur Peptide Synthetases of Bacterial Peptidoglycan Synthesis and Their Modification by Site-Directed Mutagenesis in the UDP-MurNAc:l-Alanine Ligase from Escherichia coli

scientific article from 1997

Mechanistic Analysis of Muraymycin Analogues: A Guide to the Design of MraY Inhibitors

article

Membrane Topology and Biochemical Characterization of the Escherichia coli BacA Undecaprenyl-Pyrophosphate Phosphatase

scientific article

MpaA is a murein-tripeptide-specific zinc carboxypeptidase that functions as part of a catabolic pathway for peptidoglycan-derived peptides in γ-proteobacteria

scientific article

MppA, a Periplasmic Binding Protein Essential for Import of the Bacterial Cell Wall Peptide l -Alanyl-γ- d -Glutamyl- meso -Diaminopimelate ⬇️

scientific article published on March 1, 1998

MurD enzymes from different bacteria: Evaluation of inhibitors

scientific article published on 15 June 2012

MurD enzymes: some recent developments

scientific article

Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin

scientific article

Nucleotide sequence of the murD gene encoding the UDP-MurNAc-L-Ala-D-Glu synthetase of Escherichia coli.

scientific article published in January 1990

Nucleotide sequence of the murF gene encoding the UDP-MurNAc-pentapeptide synthetase of Escherichia coli

scientific article

PGRP-SD, an Extracellular Pattern-Recognition Receptor, Enhances Peptidoglycan-Mediated Activation of the Drosophila Imd Pathway

scientific article published on November 2016

Peptidoglycan biosynthesis in Escherichia coli: variations in the metabolism of alanine and D-alanyl-D-alanine.

scientific article published in August 1992

Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2.

scientific article

Peptidoglycan molecular requirements allowing detection by the Drosophila immune deficiency pathway

scientific article

Peptidoglycan precursor pools associated with MraY and FtsW deficiencies or antibiotic treatments

scientific article published in September 2005

Periplasmic phosphorylation of lipid A is linked to the synthesis of undecaprenyl phosphate

scientific article

Pool levels of UDP N-acetylglucosamine and UDP N-acetylglucosamine-enolpyruvate in Escherichia coli and correlation with peptidoglycan synthesis ⬇️

scientific article published on June 1, 1983

Preparative enzymatic synthesis of polyprenyl-pyrophosphoryl-N-acetylglucosamine, an essential lipid intermediate for the biosynthesis of various bacterial cell envelope polymers

scientific journal article

Probing the Role of Cysteine Residues in Glucosamine-1-Phosphate Acetyltransferase Activity of the Bifunctional GlmU Protein from Escherichia coli : Site-Directed Mutagenesis and Characterization of the Mutant Enzymes ⬇️

scientific article published on September 1, 1998

Purification and biochemical characterisation of GlmU from Yersinia pestis

scientific article published on 23 November 2014

Purification and biochemical characterization of Mur ligases from Staphylococcus aureus

scientific article published on 24 July 2010

Purification and characterization of the bacterial MraY translocase catalyzing the first membrane step of peptidoglycan biosynthesis

scientific article

Purification and characterization of the bacterial UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase WecA

scientific journal article

Quantitative high-performance liquid chromatography analysis of the pool levels of undecaprenyl phosphate and its derivatives in bacterial membranes

scientific article

Reaction mechanism of phosphoglucosamine mutase from Escherichia coli.

scientific article

Reverse-phase high-pressure liquid chromatography of uridine diphosphate N-acetylmuramyl peptide precursors of bacterial cell wall peptidoglycan

scientific article published on 01 June 1981

Role of AmiA in the morphological transition of Helicobacter pylori and in immune escape

scientific article

Role of class A penicillin-binding proteins in PBP5-mediated beta-lactam resistance in Enterococcus faecalis

scientific article

Role of the Ortholog and Paralog Amino Acid Invariants in the Active Site of the UDP-MurNAc-l-alanine:d-glutamate Ligase (MurD)†

scientific article published on 01 September 1999

Role of the amino acid invariants in the active site of MurG as evaluated by site-directed mutagenesis.

scientific article published on 5 July 2007

Specific interactions of clausin, a new lantibiotic, with lipid precursors of the bacterial cell wall

scientific article published on September 2009

Specificity Determinants for Lysine Incorporation in Staphylococcus aureus Peptidoglycan as Revealed by the Structure of a MurE Enzyme Ternary Complex

scientific article

Structural and biochemical characterization of the β-N-acetylglucosaminidase from Thermotoga maritima: toward rationalization of mechanistic knowledge in the GH73 family

scientific article

Structural basis of adaptor-mediated protein degradation by the tail-specific PDZ-protease Prc.

scientific article

Structure and Function of a Novel LD-Carboxypeptidase A Involved in Peptidoglycan Recycling

scientific article

Structure and Function of the First Full-Length Murein Peptide Ligase (Mpl) Cell Wall Recycling Protein

scientific article

Structure and metabolism of peptidoglycan and molecular requirements allowing its detection by the Drosophila innate immune system

scientific article

Structure of Tracheal Cytotoxin in Complex with a Heterodimeric Pattern-Recognition Receptor

scientific article

Structure of the ectodomain of Drosophila peptidoglycan-recognition protein LCa suggests a molecular mechanism for pattern recognition

scientific article

Structure-activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF

scientific article published in August 2013

Structure-guided functional characterization of DUF1460 reveals a highly specific NlpC/P60 amidase family

scientific article

Substrate specificity and membrane topology of Escherichia coli PgpB, an undecaprenyl pyrophosphate phosphatase

scientific article published on 14 April 2008

Substrate-induced inactivation of the Escherichia coli AmiD N-acetylmuramoyl-L-alanine amidase highlights a new strategy to inhibit this class of enzyme

scientific article published on 23 February 2009

Synergistic enhancement of Toll-like receptor responses by NOD1 activation

article

Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists

scientific article published in August 2005

Synthesis and inhibition properties of conformational probes for the mutase-catalyzed UDP-galactopyranose/furanose interconversion.

scientific article published on December 2003

Synthesis of the L-alanyl-L-alanine cross-bridge of Enterococcus faecalis peptidoglycan

scientific article published on 24 September 2002

Synthetic tripeptides as alternate substrates of murein peptide ligase (Mpl).

scientific article published on 25 December 2012

The Drosophila amidase PGRP-LB modulates the immune response to bacterial infection.

scientific article published in April 2006

The Drosophila immune system detects bacteria through specific peptidoglycan recognition

scientific article published in May 2003

The Helicobacter pylori ureC gene codes for a phosphoglucosamine mutase

scientific article

The MurC ligase essential for peptidoglycan biosynthesis is regulated by the serine/threonine protein kinase PknA in Corynebacterium glutamicum

scientific journal article

The MurE synthetase from Thermotoga maritima is endowed with an unusual D-lysine adding activity

scientific article

The MurG glycosyltransferase provides an oligomeric scaffold for the cytoplasmic steps of peptidoglycan biosynthesis in the human pathogen Bordetella pertussis

scientific article published on 15 March 2019

The bacA gene of Escherichia coli encodes an undecaprenyl pyrophosphate phosphatase activity

scientific article

The biosynthesis of peptidoglycan lipid-linked intermediates

scientific article published on 10 December 2007

The elucidation of the structure of Thermotoga maritima peptidoglycan reveals two novel types of cross-link

scientific article

The essential peptidoglycan glycosyltransferase MurG forms a complex with proteins involved in lateral envelope growth as well as with proteins involved in cell division in Escherichia coli

scientific article published on 19 July 2007

The extended conformation of the 2.9-Å crystal structure of the three-PASTA domain of a Ser/Thr kinase from the human pathogen Staphylococcus aureus

scientific article

The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists

scientific article published on 22 August 2005

The functional vanGCd cluster of Clostridium difficile does not confer vancomycin resistance

scientific article published on 12 July 2013

The glutamate racemase activity from Escherichia coli is regulated by peptidoglycan precursor UDP-N-acetylmuramoyl-L-alanine.

scientific article

The nature of Staphylococcus aureus MurA and MurZ and approaches for detection of peptidoglycan biosynthesis inhibitors

scientific article published on 3 March 2009

The phage tail tape measure protein, an inner membrane protein and a periplasmic chaperone play connected roles in the genome injection process of E. coli phage HK97.

scientific article published on 30 January 2015

Toxicity of the colicin M catalytic domain exported to the periplasm is FkpA independent.

scientific article published on 30 July 2010

UDP-N- acetylglucosamine:N -acetylmuramoyl-(pentapeptide) pyrophosphoryl undecaprenol N -acetylglucosamine transferase from Escherichia coli : overproduction, solubilization, and purification

scientific article published on 01 April 1999

Undecaprenyl Phosphate Synthesis.

scientific article

Unusual substrate specificity of the peptidoglycan MurE ligase from Erysipelothrix rhusiopathiae

scientific article published on 14 December 2015

X-Ray Structure and Site-Directed Mutagenesis Analysis of the Escherichia coli Colicin M Immunity Protein

scientific article

hPepT1 selectively transports muramyl dipeptide but not Nod1-activating muramyl peptides

scientific article

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