List of works - Giovanni Scapagnini

"Positive biology": the centenarian lesson

scientific article

A Randomized Clinical Trial Evaluating the Efficacy of an Anthocyanin-Maqui Berry Extract (Delphinol®) on Oxidative Stress Biomarkers

scientific article

A new predictive equation for evaluating women body fat percentage and obesity-related cardiovascular disease risk

scientific article published on 24 January 2014

Altered expression pattern of Nrf2/HO-1 axis during accelerated-senescence in HIV-1 transgenic rat.

scientific article published on 16 July 2014

Alzheimer's disease: new diagnostic and therapeutic tools

scientific article published on 13 August 2008

Anti-inflammatory effects of H2S during acute bacterial infection: a review

scientific article published on 10 May 2017

Antioxidants as antidepressants: fact or fiction?

scientific article published on June 2012

Antiproliferative activity of melatonin by transcriptional inhibition of cyclin D1 expression: a molecular basis for melatonin-induced oncostatic effects.

scientific article published on August 2005

Biomarkers of Brain Function and Injury: Biological and Clinical Significance.

scientific article published on 2 September 2015

Carbon monoxide signaling in promoting angiogenesis in human microvessel endothelial cells

scientific article published on 01 May 2005

Cocoa bioactive compounds: significance and potential for the maintenance of skin health

scientific article

Curcumin, inflammation, ageing and age-related diseases.

scientific article

Dietary Phytochemicals in Neuroimmunoaging: A New Therapeutic Possibility for Humans?

scientific article

Dietary phytochemicals and neuro-inflammaging: from mechanistic insights to translational challenges

scientific article

Distribution of parkin in the adult rat brain.

scientific article published in April 2002

Dose response biology of resveratrol in obesity

scientific article

Effects of acetyl-L-carnitine on the formation of fatty acid ethyl esters in brain and peripheral organs after short-term ethanol administration in rat.

scientific article published in February 2001

Enhancement of mitochondrial biogenesis with polyphenols: combined effects of resveratrol and equol in human endothelial cells ⬇️

scientific article published on July 11, 2013

Epigenetic nutraceutical diets in Alzheimer's disease.

scientific article

Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress.

scientific article published in October 2004

Extending healthy ageing: nutrient sensitive pathway and centenarian population.

scientific article

Gene expression profiles of heme oxygenase isoforms in the rat brain.

scientific article published in November 2002

Healthy aging diets other than the Mediterranean: a focus on the Okinawan diet

scientific article

Heme oxygenase overexpression attenuates glucose-mediated oxidative stress in quiescent cell phase: linking heme to hyperglycemia complications.

scientific article published in April 2005

Human heme oxygenase: cell cycle-dependent expression and DNA microarray identification of multiple gene responses after transduction of endothelial cells.

scientific article published in December 2003

Immunomodulatory and Antiaging Mechanisms of Resveratrol, Rapamycin, and Metformin: Focus on mTOR and AMPK Signaling Networks

scientific article published on 23 July 2022

In Vitro and In Vivo Biological Activity of Berberine Chloride against Uropathogenic E. coli Strains Using Galleria mellonella as a Host Model

scientific article published on 29 October 2020

Increased expression of heat shock proteins in rat brain during aging: relationship with mitochondrial function and glutathione redox state.

scientific article published in April 2004

Influence of equol and resveratrol supplementation on health-related quality of life in menopausal women: A randomized, placebo-controlled study

scientific article published on 27 November 2016

Involvement of ELAV RNA-binding proteins in the post-transcriptional regulation of HO-1.

scientific article

Mediterranean diet and longevity in Sicily: survey in a Sicani Mountains population.

scientific article published in April 2012

Modulation of Nrf2/ARE Pathway by Food Polyphenols: A Nutritional Neuroprotective Strategy for Cognitive and Neurodegenerative Disorders ⬇️

scientific article published on April 19, 2011

Molecular chaperones and their roles in neural cell differentiation.

scientific article

Muscle uncoupling protein 3 expression is unchanged by chronic ephedrine/caffeine treatment: results of a double blind, randomised clinical trial in morbidly obese females

scientific article

Neurofibromin and Amyloid Precursor Protein Expression in Dopamine D3 Receptor Knock-Out Mice Brains ⬇️

scientific article published on December 19, 2010

Neuroprotective effect of silibinin in diabetic mice.

scientific article

New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways. And new drug candidates--Nrf2 activators and GSK-3 inhibitors.

scientific article published on 24 January 2012

Nutrigerontology: a key for achieving successful ageing and longevity

scientific article published on 21 May 2016

Pleiotropic protective effects of phytochemicals in Alzheimer's disease

scientific article

Polyphenols: a Promising Nutritional Approach to Prevent or Reduce the Progression of Prehypertension.

scientific article

Probiotics and oral health

scientific article published on 01 January 2012

Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: a nutritional approach.

scientific article published on 7 November 2003

Relaxin potentiates the expression of inducible nitric oxide synthase by endothelial cells from human umbilical vein in in vitro culture.

scientific article published on 16 March 2004

Resveratrol, Rapamycin and Metformin as Modulators of Antiviral Pathways

scientific article published on 17 December 2020

Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer's Dementia.

scientific article

Sex hormonal regulation and hormesis in aging and longevity: role of vitagenes

scientific article

Sulfur compounds block MCP-1 production by Mycoplasma fermentans-infected macrophages through NF-κB inhibition

scientific article published on 24 May 2014

Synergistic effect of L-Carnosine and EGCG in the prevention of physiological brain aging

scientific article published in January 2013

The "Alzheimer's disease signature": potential perspectives for novel biomarkers.

scientific article

The major green tea polyphenol, (-)-epigallocatechin-3-gallate, induces heme oxygenase in rat neurons and acts as an effective neuroprotective agent against oxidative stress.

scientific article published on August 2009

The potential protective effect of tramiprosate (homotaurine) against Alzheimer's disease: a review

scientific article published on September 5, 2012

Therapeutic Potential of Dietary Polyphenols against Brain Ageing and Neurodegenerative Disorders ⬇️

scientific article published on January 1, 2010

Traditional uses, chemical composition and biological activities of Sideritis raeseri Boiss. & Heldr.

scientific article published on 25 June 2016

List of works by Giovanni Scapagnini

"Positive biology": the centenarian lesson

A Randomized Clinical Trial Evaluating the Efficacy of an Anthocyanin-Maqui Berry Extract (Delphinol®) on Oxidative Stress Biomarkers

A new predictive equation for evaluating women body fat percentage and obesity-related cardiovascular disease risk

Altered expression pattern of Nrf2/HO-1 axis during accelerated-senescence in HIV-1 transgenic rat.

Alzheimer's disease: new diagnostic and therapeutic tools

Anti-inflammatory effects of H2S during acute bacterial infection: a review

Antioxidants as antidepressants: fact or fiction?

Antiproliferative activity of melatonin by transcriptional inhibition of cyclin D1 expression: a molecular basis for melatonin-induced oncostatic effects.

Biomarkers of Brain Function and Injury: Biological and Clinical Significance.

Carbon monoxide signaling in promoting angiogenesis in human microvessel endothelial cells

Cocoa bioactive compounds: significance and potential for the maintenance of skin health

Curcumin, inflammation, ageing and age-related diseases.

Dietary Phytochemicals in Neuroimmunoaging: A New Therapeutic Possibility for Humans?

Dietary phytochemicals and neuro-inflammaging: from mechanistic insights to translational challenges

Distribution of parkin in the adult rat brain.

Dose response biology of resveratrol in obesity

Effects of acetyl-L-carnitine on the formation of fatty acid ethyl esters in brain and peripheral organs after short-term ethanol administration in rat.

Enhancement of mitochondrial biogenesis with polyphenols: combined effects of resveratrol and equol in human endothelial cells ⬇️

Epigenetic nutraceutical diets in Alzheimer's disease.

Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress.

Extending healthy ageing: nutrient sensitive pathway and centenarian population.

Gene expression profiles of heme oxygenase isoforms in the rat brain.

Healthy aging diets other than the Mediterranean: a focus on the Okinawan diet

Heme oxygenase overexpression attenuates glucose-mediated oxidative stress in quiescent cell phase: linking heme to hyperglycemia complications.

Human heme oxygenase: cell cycle-dependent expression and DNA microarray identification of multiple gene responses after transduction of endothelial cells.

Immunomodulatory and Antiaging Mechanisms of Resveratrol, Rapamycin, and Metformin: Focus on mTOR and AMPK Signaling Networks

In Vitro and In Vivo Biological Activity of Berberine Chloride against Uropathogenic E. coli Strains Using Galleria mellonella as a Host Model

Increased expression of heat shock proteins in rat brain during aging: relationship with mitochondrial function and glutathione redox state.

Influence of equol and resveratrol supplementation on health-related quality of life in menopausal women: A randomized, placebo-controlled study

Involvement of ELAV RNA-binding proteins in the post-transcriptional regulation of HO-1.

Mediterranean diet and longevity in Sicily: survey in a Sicani Mountains population.

Modulation of Nrf2/ARE Pathway by Food Polyphenols: A Nutritional Neuroprotective Strategy for Cognitive and Neurodegenerative Disorders ⬇️

Molecular chaperones and their roles in neural cell differentiation.

Muscle uncoupling protein 3 expression is unchanged by chronic ephedrine/caffeine treatment: results of a double blind, randomised clinical trial in morbidly obese females

Neurofibromin and Amyloid Precursor Protein Expression in Dopamine D3 Receptor Knock-Out Mice Brains ⬇️

Neuroprotective effect of silibinin in diabetic mice.

New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways. And new drug candidates--Nrf2 activators and GSK-3 inhibitors.

Nutrigerontology: a key for achieving successful ageing and longevity

Pleiotropic protective effects of phytochemicals in Alzheimer's disease

Polyphenols: a Promising Nutritional Approach to Prevent or Reduce the Progression of Prehypertension.

Probiotics and oral health

Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: a nutritional approach.

Relaxin potentiates the expression of inducible nitric oxide synthase by endothelial cells from human umbilical vein in in vitro culture.

Resveratrol, Rapamycin and Metformin as Modulators of Antiviral Pathways

Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer's Dementia.

Sex hormonal regulation and hormesis in aging and longevity: role of vitagenes

Sulfur compounds block MCP-1 production by Mycoplasma fermentans-infected macrophages through NF-κB inhibition

Synergistic effect of L-Carnosine and EGCG in the prevention of physiological brain aging

The "Alzheimer's disease signature": potential perspectives for novel biomarkers.

The major green tea polyphenol, (-)-epigallocatechin-3-gallate, induces heme oxygenase in rat neurons and acts as an effective neuroprotective agent against oxidative stress.

The potential protective effect of tramiprosate (homotaurine) against Alzheimer's disease: a review

Therapeutic Potential of Dietary Polyphenols against Brain Ageing and Neurodegenerative Disorders ⬇️

Traditional uses, chemical composition and biological activities of Sideritis raeseri Boiss. & Heldr.