List of works - Michela Matteoli

Storage and release of ATP from astrocytes in culture

scientific article

Astrocyte-derived ATP induces vesicle shedding and IL-1 beta release from microglia

scientific journal article

Hardwiring the brain: endocannabinoids shape neuronal connectivity

scientific article published on May 2007

Primary structure and cellular localization of chicken brain myosin-V (p190), an unconventional myosin with calmodulin light chains

scientific article published on December 1, 1992

LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool

scientific article

Vesicular transmitter release from astrocytes

scientific article published on November 2006

Synaptic vesicle dynamics in living cultured hippocampal neurons visualized with CY3-conjugated antibodies directed against the lumenal domain of synaptotagmin

scientific article published in June 1995

GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion.

scientific article published on May 1991

Nucleotide-mediated calcium signaling in rat cortical astrocytes: Role of P2X and P2Y receptors

scientific article published in September 2003

Myeloid microvesicles are a marker and therapeutic target for neuroinflammation

scientific article published in October 2012

Synaptic vesicle proteins and early endosomes in cultured hippocampal neurons: differential effects of Brefeldin A in axon and dendrites.

scientific article published on September 1993

Microvesicles released from microglia stimulate synaptic activity via enhanced sphingolipid metabolism.

scientific article published on 13 January 2012

A regulated secretory pathway in cultured hippocampal astrocytes.

scientific article

Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor protein.

scientific article published on May 1994

Astrocytes as secretory cells of the central nervous system: idiosyncrasies of vesicular secretion

scientific article published on 12 January 2016

Cholesterol reduction impairs exocytosis of synaptic vesicles

scientific article

Microglial microvesicle secretion and intercellular signaling.

scientific article published on 22 May 2012

A common exocytotic mechanism mediates axonal and dendritic outgrowth.

scientific article

Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles.

scientific article published on 13 December 2013

Synaptobrevin2-expressing vesicles in rat astrocytes: insights into molecular characterization, dynamics and exocytosis.

scientific article published in December 2005

Isoforms of the Na,K-ATPase are present in both axons and dendrites of hippocampal neurons in culture

scientific article published on September 15, 1992

Pathophysiological roles of extracellular nucleotides in glial cells: differential expression of purinergic receptors in resting and activated microglia

Uptake and recycling of pro-BDNF for transmitter-induced secretion by cortical astrocytes

scientific article

Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF)

scientific article

Chronic blockade of glutamate receptors enhances presynaptic release and downregulates the interaction between synaptophysin-synaptobrevin-vesicle-associated membrane protein 2.

scientific article

A role for P2X7 in microglial proliferation

scientific article published on 6 July 2006

Activity-dependent phosphorylation of Ser187 is required for SNAP-25-negative modulation of neuronal voltage-gated calcium channels.

scholarly article

Hippocampal neurons recycle BDNF for activity-dependent secretion and LTP maintenance.

scientific article

The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity

scientific article published on 08 May 2018

LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex

scientific article

Unique luminal localization of VGAT-C terminus allows for selective labeling of active cortical GABAergic synapses

scientific article published on December 2008

Active endocannabinoids are secreted on extracellular membrane vesicles.

scientific article published on 7 January 2015

Tetanus toxin blocks the exocytosis of synaptic vesicles clustered at synapses but not of synaptic vesicles in isolated axons

scientific article published on August 1999

Internalization and proteolytic action of botulinum toxins in CNS neurons and astrocytes.

scientific article

Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain

scientific article

Mutant PrP suppresses glutamatergic neurotransmission in cerebellar granule neurons by impairing membrane delivery of VGCC α(2)δ-1 Subunit

scientific journal article

TI-VAMP/VAMP7 is the SNARE of secretory lysosomes contributing to ATP secretion from astrocytes.

scientific article published on 11 January 2012

Analysis of SNAP-25 immunoreactivity in hippocampal inhibitory neurons during development in culture and in situ.

scientific article

The role of glial cells in synaptic function

scientific article

Localization and functional relevance of system a neutral amino acid transporters in cultured hippocampal neurons.

scientific article published on 11 January 2002

Endogenous SNAP-25 regulates native voltage-gated calcium channels in glutamatergic neurons

scientific article

Calcium-dependent glutamate release during neuronal development and synaptogenesis: different involvement of omega-agatoxin IVA- and omega-conotoxin GVIA-sensitive channels.

scientific article

Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs

scientific journal article

VGLUT1 and VGAT are sorted to the same population of synaptic vesicles in subsets of cortical axon terminals

scientific journal article

Synaptogenesis in hippocampal cultures.

scientific article

Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons

scientific article published on 27 August 2002

Traffic of botulinum toxins A and E in excitatory and inhibitory neurons.

scientific article

Entering neurons: botulinum toxins and synaptic vesicle recycling

scientific article published on October 2006

Spatial changes in calcium signaling during the establishment of neuronal polarity and synaptogenesis.

scientific article published in September 1994

List of works by Michela Matteoli

Storage and release of ATP from astrocytes in culture

Astrocyte-derived ATP induces vesicle shedding and IL-1 beta release from microglia

Hardwiring the brain: endocannabinoids shape neuronal connectivity

Primary structure and cellular localization of chicken brain myosin-V (p190), an unconventional myosin with calmodulin light chains

LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool

Vesicular transmitter release from astrocytes

Synaptic vesicle dynamics in living cultured hippocampal neurons visualized with CY3-conjugated antibodies directed against the lumenal domain of synaptotagmin

GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion.

Nucleotide-mediated calcium signaling in rat cortical astrocytes: Role of P2X and P2Y receptors

Myeloid microvesicles are a marker and therapeutic target for neuroinflammation

Synaptic vesicle proteins and early endosomes in cultured hippocampal neurons: differential effects of Brefeldin A in axon and dendrites.

Microvesicles released from microglia stimulate synaptic activity via enhanced sphingolipid metabolism.

A regulated secretory pathway in cultured hippocampal astrocytes.

Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor protein.

Astrocytes as secretory cells of the central nervous system: idiosyncrasies of vesicular secretion

Cholesterol reduction impairs exocytosis of synaptic vesicles

Microglial microvesicle secretion and intercellular signaling.

A common exocytotic mechanism mediates axonal and dendritic outgrowth.

Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles.

Synaptobrevin2-expressing vesicles in rat astrocytes: insights into molecular characterization, dynamics and exocytosis.

Isoforms of the Na,K-ATPase are present in both axons and dendrites of hippocampal neurons in culture

Pathophysiological roles of extracellular nucleotides in glial cells: differential expression of purinergic receptors in resting and activated microglia

Uptake and recycling of pro-BDNF for transmitter-induced secretion by cortical astrocytes

Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF)

Chronic blockade of glutamate receptors enhances presynaptic release and downregulates the interaction between synaptophysin-synaptobrevin-vesicle-associated membrane protein 2.

A role for P2X7 in microglial proliferation

Activity-dependent phosphorylation of Ser187 is required for SNAP-25-negative modulation of neuronal voltage-gated calcium channels.

Hippocampal neurons recycle BDNF for activity-dependent secretion and LTP maintenance.

The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity

LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex

Unique luminal localization of VGAT-C terminus allows for selective labeling of active cortical GABAergic synapses

Active endocannabinoids are secreted on extracellular membrane vesicles.

Tetanus toxin blocks the exocytosis of synaptic vesicles clustered at synapses but not of synaptic vesicles in isolated axons

Internalization and proteolytic action of botulinum toxins in CNS neurons and astrocytes.

Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain

Mutant PrP suppresses glutamatergic neurotransmission in cerebellar granule neurons by impairing membrane delivery of VGCC α(2)δ-1 Subunit

TI-VAMP/VAMP7 is the SNARE of secretory lysosomes contributing to ATP secretion from astrocytes.

Analysis of SNAP-25 immunoreactivity in hippocampal inhibitory neurons during development in culture and in situ.

The role of glial cells in synaptic function

Localization and functional relevance of system a neutral amino acid transporters in cultured hippocampal neurons.

Endogenous SNAP-25 regulates native voltage-gated calcium channels in glutamatergic neurons

Calcium-dependent glutamate release during neuronal development and synaptogenesis: different involvement of omega-agatoxin IVA- and omega-conotoxin GVIA-sensitive channels.

Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs

VGLUT1 and VGAT are sorted to the same population of synaptic vesicles in subsets of cortical axon terminals

Synaptogenesis in hippocampal cultures.

Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons

Traffic of botulinum toxins A and E in excitatory and inhibitory neurons.

Entering neurons: botulinum toxins and synaptic vesicle recycling

Spatial changes in calcium signaling during the establishment of neuronal polarity and synaptogenesis.

Myeloid microvesicles in cerebrospinal fluid are associated with myelin damage and neuronal loss in mild cognitive impairment and Alzheimer disease