List of works - Anna Mondino

A Conformational Change in Cytochromecof Apoptotic and Necrotic Cells Is Detected by Monoclonal Antibody Binding and Mimicked by Association of the Native Antigen with Synthetic Phospholipid Vesicles†

scientific article published on 01 March 1999

A natural immunological adjuvant enhances T cell clonal expansion through a CD28-dependent, interleukin (IL)-2-independent mechanism

scientific article published in January 1998

A signaling loop of REST, TSC2 and β-catenin governs proliferation and function of PC12 neural cells

scientific article

A tyrosine protein kinase activated by bombesin in normal fibroblasts and small cell carcinomas.

scientific article published on January 1988

Absence of Rac1 and Rac3 GTPases in the nervous system hinders thymic, splenic and immune-competence development

scientific article published on 15 April 2011

Accumulation of Sequence-specific RNA-binding Proteins in the Cytosol of Activated T Cells Undergoing RNA Degradation and Apoptosis

scientific article published in Journal of Biological Chemistry

Adoptive T-cell therapy for cancer: The era of engineered T cells

scientific article (publication date: September 2015)

Antigen-experienced CD4(+) T cells limit naïve T-cell priming in response to therapeutic vaccination in vivo

scientific article

Autonomic denervation of lymphoid organs leads to epigenetic immune atrophy in a mouse model of Krabbe disease.

scientific article published in December 2007

Basophil Recruitment into Tumor-Draining Lymph Nodes Correlates with Th2 Inflammation and Reduced Survival in Pancreatic Cancer Patients

scientific article

Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells

scientific article published in Science

Booster vaccinations against cancer are critical in prophylactic but detrimental in therapeutic settings

scientific article published on 28 March 2013

Boosting Interleukin-12 Antitumor Activity and Synergism with Immunotherapy by Targeted Delivery with isoDGR-Tagged Nanogold

scientific article published on 16 September 2019

CD28 Signaling Augments Elk-1-Dependent Transcription at the c-fos Gene During Antigen Stimulation

article

Changes in the immune responses against human herpesvirus-8 in the disease course of posttransplant Kaposi sarcoma

scientific article

Clonal anergy is maintained independently of T cell proliferation

scientific article published in December 2002

Concomitant Tumor and Minor Histocompatibility Antigen–Specific Immunity Initiate Rejection and Maintain Remission from Established Spontaneous Solid Tumors

scientific article published on 13 April 2010

Concurrent allorecognition has a limited impact on posttransplant vaccination

scientific article published on 5 January 2011

Constitutive active p21ras enhances primary T cell responsiveness to Ca2+ signals without interfering with the induction of clonal anergy

scientific article

Correction: Monoallelic Germline TSC1 Mutations Are Permissive for T Lymphocyte Development and Homeostasis in Tuberous Sclerosis Complex Individuals

scientific article published on 07 June 2019

Critical impact of the kinetics of dendritic cells activation on the in vivo induction of tumor-specific T lymphocytes.

scientific article published in July 2003

Cytosolic sequestration of Prep1 influences early stages of T cell development

scientific article

Defective transcription of the IL-2 gene is associated with impaired expression of c-Fos, FosB, and JunB in anergic T helper 1 cells

article

Direct evidence that functionally impaired CD4+ T cells persist in vivo following induction of peripheral tolerance

article

Exploiting cytokines in adoptive T-cell therapy of cancer

scientific article published on June 2015

Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation

scientific journal article

FOXP3+ T Cells Recruited to Sites of Sterile Skeletal Muscle Injury Regulate the Fate of Satellite Cells and Guide Effective Tissue Regeneration

scientific article published on 3 June 2015

IL-17A impairs host tolerance during airway chronic infection by Pseudomonas aeruginosa

scientific article

IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes

scientific article

IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors.

scientific article published on 15 November 2012

IL-7 is superior to IL-2 for ex vivo expansion of tumour-specific CD4(+) T cells

scientific article

Immune surveillance and anti-tumor immune responses: an anatomical perspective

scientific article

In vivo detection of dendritic cell antigen presentation to CD4(+) T cells.

scientific article

Inflammatory cytokines enhance the in vivo clonal expansion and differentiation of antigen-activated CD4+ T cells ⬇️

scientific article published on July 15, 1997

Interleukin-7 Unveils Pathogen-Specific T Cells by Enhancing Antigen-Recall Responses

scientific article published on 28 February 2018

Involvement of Prep1 in the alphabeta T-cell receptor T-lymphocytic potential of hematopoietic precursors

scientific article

Metabolic determinants of the immune modulatory function of neural stem cells

scientific article published on 02 September 2016

Monoallelic germline TSC1 mutations are permissive for T lymphocyte development and homeostasis in tuberous sclerosis complex individuals

scientific article

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease.

scientific article

Phenotype and homing of CD4 tumor-specific T cells is modulated by tumor bulk.

scientific article published on July 2005

Prolonged TCR/CD28 engagement drives IL-2-independent T cell clonal expansion through signaling mediated by the mammalian target of rapamycin

scientific article

Prostate cancer stem cells are targets of both innate and adaptive immunity and elicit tumor-specific immune responses

scientific article published on 16 April 2013

Rapamycin-sensitive signals control TCR/CD28-driven Ifng, Il4 and Foxp3 transcription and promoter region methylation

scientific article

Redirecting the immune response: role of adoptive T cell therapy

scientific article

Reduced functional avidity promotes central and effector memory CD4 T cell responses to tumor-associated antigens

scientific article published on 3 November 2010

Reply to Salvador Vale's Letter to the Editor re: Cesare Cozzarini. Whole-pelvis Radiotherapy in the Radiation Treatment of Intermediate- and High-risk Prostate Cancer: How to Improve the Therapeutic Ratio of a Potentially Effective but still Unsati

scientific article published on 14 February 2017

Synthetic CD4+ T cell-targeted antigen-presenting cells elicit protective antitumor responses

scientific article published in April 2008

T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors.

scientific article

T cell therapy against cancer: A predictive diffuse-interface mathematical model informed by pre-clinical studies

scientific article published in 2022

TCR gene-engineered T cell: limited T cell activation and combined use of IL-15 and IL-21 ensure minimal differentiation and maximal antigen-specificity

scientific article

Targeted inactivation of the COP9 signalosome impairs multiple stages of T cell development

scientific article published on 11 February 2008

Targeting TNF- to Neoangiogenic Vessels Enhances Lymphocyte Infiltration in Tumors and Increases the Therapeutic Potential of Immunotherapy

scientific article published on 08 February 2012

Targeting Tumor Vasculature with TNF Leads Effector T Cells to the Tumor and Enhances Therapeutic Efficacy of Immune Checkpoint Blockers in Combination with Adoptive Cell Therapy.

scientific article published on 28 February 2018

Targeting the tumor and its associated stroma: One and one can make three in adoptive T cell therapy of solid tumors.

scientific article published on 15 June 2017

The Transcriptional Regulator Sin3A Contributes to the Oncogenic Potential of STAT3

scientific article published on 28 January 2019

The c-met/HGF receptor in human tumours.

scientific article published on October 1992

The host genetic background defines diverse immune-reactivity and susceptibility to chronic Pseudomonas aeruginosa respiratory infection

scientific article published on 16 November 2016

The immunogenicity of dendritic cell-based vaccines is not hampered by doxorubicin and melphalan administration

scientific article

The soluble D2D3(88-274) fragment of the urokinase receptor inhibits monocyte chemotaxis and integrin-dependent cell adhesion

scientific article

The tuberous sclerosis complex: balancing proliferation and survival

scientific article published on April 2011

Transplant Site Influences the Immune Response After Islet Transplantation: Bone Marrow Versus Liver

scientific article published on 29 August 2016

Trick to treat: tricking the thymus to treat cancer.

scientific article published in July 2013

Tumor-targeting vaccination instructs graft-vs.-tumor immune responses

scientific article published on 12 September 2013

Tumors hamper the immunogenic competence of CD4+ T cell-directed dendritic cell vaccination

scientific article published in September 2007

Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor

scientific article

Vaccine-instructed intratumoral IFN-γ enables regression of autochthonous mouse prostate cancer in allogeneic T-cell transplantation

scientific article published on 7 June 2013

Vascular targeting, chemotherapy and active immunotherapy: teaming up to attack cancer

scientific article published on 28 March 2008

mTOR at the crossroads of T cell proliferation and tolerance

scientific article published on 23 March 2007

uPA and uPAR in fibrinolysis, immunity and pathology

scientific article published in August 2004

List of works by Anna Mondino

A Conformational Change in Cytochromecof Apoptotic and Necrotic Cells Is Detected by Monoclonal Antibody Binding and Mimicked by Association of the Native Antigen with Synthetic Phospholipid Vesicles†

A natural immunological adjuvant enhances T cell clonal expansion through a CD28-dependent, interleukin (IL)-2-independent mechanism

A signaling loop of REST, TSC2 and β-catenin governs proliferation and function of PC12 neural cells

A tyrosine protein kinase activated by bombesin in normal fibroblasts and small cell carcinomas.

Absence of Rac1 and Rac3 GTPases in the nervous system hinders thymic, splenic and immune-competence development

Accumulation of Sequence-specific RNA-binding Proteins in the Cytosol of Activated T Cells Undergoing RNA Degradation and Apoptosis

Adoptive T-cell therapy for cancer: The era of engineered T cells

Antigen-experienced CD4(+) T cells limit naïve T-cell priming in response to therapeutic vaccination in vivo

Autonomic denervation of lymphoid organs leads to epigenetic immune atrophy in a mouse model of Krabbe disease.

Basophil Recruitment into Tumor-Draining Lymph Nodes Correlates with Th2 Inflammation and Reduced Survival in Pancreatic Cancer Patients

Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells

Booster vaccinations against cancer are critical in prophylactic but detrimental in therapeutic settings

Boosting Interleukin-12 Antitumor Activity and Synergism with Immunotherapy by Targeted Delivery with isoDGR-Tagged Nanogold

CD28 Signaling Augments Elk-1-Dependent Transcription at the c-fos Gene During Antigen Stimulation

Changes in the immune responses against human herpesvirus-8 in the disease course of posttransplant Kaposi sarcoma

Clonal anergy is maintained independently of T cell proliferation

Concomitant Tumor and Minor Histocompatibility Antigen–Specific Immunity Initiate Rejection and Maintain Remission from Established Spontaneous Solid Tumors

Concurrent allorecognition has a limited impact on posttransplant vaccination

Constitutive active p21ras enhances primary T cell responsiveness to Ca2+ signals without interfering with the induction of clonal anergy

Correction: Monoallelic Germline TSC1 Mutations Are Permissive for T Lymphocyte Development and Homeostasis in Tuberous Sclerosis Complex Individuals

Critical impact of the kinetics of dendritic cells activation on the in vivo induction of tumor-specific T lymphocytes.

Cytosolic sequestration of Prep1 influences early stages of T cell development

Defective transcription of the IL-2 gene is associated with impaired expression of c-Fos, FosB, and JunB in anergic T helper 1 cells

Direct evidence that functionally impaired CD4+ T cells persist in vivo following induction of peripheral tolerance

Exploiting cytokines in adoptive T-cell therapy of cancer

Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation

FOXP3+ T Cells Recruited to Sites of Sterile Skeletal Muscle Injury Regulate the Fate of Satellite Cells and Guide Effective Tissue Regeneration

IL-17A impairs host tolerance during airway chronic infection by Pseudomonas aeruginosa

IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes

IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors.

IL-7 is superior to IL-2 for ex vivo expansion of tumour-specific CD4(+) T cells

Immune surveillance and anti-tumor immune responses: an anatomical perspective

In vivo detection of dendritic cell antigen presentation to CD4(+) T cells.

Inflammatory cytokines enhance the in vivo clonal expansion and differentiation of antigen-activated CD4+ T cells ⬇️

Interleukin-7 Unveils Pathogen-Specific T Cells by Enhancing Antigen-Recall Responses

Involvement of Prep1 in the alphabeta T-cell receptor T-lymphocytic potential of hematopoietic precursors

Metabolic determinants of the immune modulatory function of neural stem cells

Monoallelic germline TSC1 mutations are permissive for T lymphocyte development and homeostasis in tuberous sclerosis complex individuals

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease.

Phenotype and homing of CD4 tumor-specific T cells is modulated by tumor bulk.

Prolonged TCR/CD28 engagement drives IL-2-independent T cell clonal expansion through signaling mediated by the mammalian target of rapamycin

Prostate cancer stem cells are targets of both innate and adaptive immunity and elicit tumor-specific immune responses

Rapamycin-sensitive signals control TCR/CD28-driven Ifng, Il4 and Foxp3 transcription and promoter region methylation

Redirecting the immune response: role of adoptive T cell therapy

Reduced functional avidity promotes central and effector memory CD4 T cell responses to tumor-associated antigens

Reply to Salvador Vale's Letter to the Editor re: Cesare Cozzarini. Whole-pelvis Radiotherapy in the Radiation Treatment of Intermediate- and High-risk Prostate Cancer: How to Improve the Therapeutic Ratio of a Potentially Effective but still Unsati

Synthetic CD4+ T cell-targeted antigen-presenting cells elicit protective antitumor responses

T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors.

T cell therapy against cancer: A predictive diffuse-interface mathematical model informed by pre-clinical studies

TCR gene-engineered T cell: limited T cell activation and combined use of IL-15 and IL-21 ensure minimal differentiation and maximal antigen-specificity

Targeted inactivation of the COP9 signalosome impairs multiple stages of T cell development

Targeting TNF- to Neoangiogenic Vessels Enhances Lymphocyte Infiltration in Tumors and Increases the Therapeutic Potential of Immunotherapy

Targeting Tumor Vasculature with TNF Leads Effector T Cells to the Tumor and Enhances Therapeutic Efficacy of Immune Checkpoint Blockers in Combination with Adoptive Cell Therapy.

Targeting the tumor and its associated stroma: One and one can make three in adoptive T cell therapy of solid tumors.

The Transcriptional Regulator Sin3A Contributes to the Oncogenic Potential of STAT3

The c-met/HGF receptor in human tumours.

The host genetic background defines diverse immune-reactivity and susceptibility to chronic Pseudomonas aeruginosa respiratory infection

The immunogenicity of dendritic cell-based vaccines is not hampered by doxorubicin and melphalan administration

The soluble D2D3(88-274) fragment of the urokinase receptor inhibits monocyte chemotaxis and integrin-dependent cell adhesion

The tuberous sclerosis complex: balancing proliferation and survival

Transplant Site Influences the Immune Response After Islet Transplantation: Bone Marrow Versus Liver

Trick to treat: tricking the thymus to treat cancer.

Tumor-targeting vaccination instructs graft-vs.-tumor immune responses

Tumors hamper the immunogenic competence of CD4+ T cell-directed dendritic cell vaccination

Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor

Vaccine-instructed intratumoral IFN-γ enables regression of autochthonous mouse prostate cancer in allogeneic T-cell transplantation

Vascular targeting, chemotherapy and active immunotherapy: teaming up to attack cancer

mTOR at the crossroads of T cell proliferation and tolerance

uPA and uPAR in fibrinolysis, immunity and pathology