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List of works by Edgard Graner

A Reductionist Approach Using Primary and Metastatic Cell-Derived Extracellular Vesicles Reveals Hub Proteins Associated with Oral Cancer Prognosis

scientific article published on 27 June 2021

ADAM17 mediates OSCC development in an orthotopic murine model.

scientific article published on 5 February 2014

Activin A immunoexpression as predictor of occult lymph node metastasis and overall survival in oral tongue squamous cell carcinoma

scientific article published on 03 April 2014

Activin A triggers angiogenesis via regulation of VEGFA and its overexpression is associated with poor prognosis of oral squamous cell carcinoma

scientific article published on 04 May 2020

Agrin and perlecan mediate tumorigenic processes in oral squamous cell carcinoma.

scientific article published on 15 December 2014

Analysis of susceptibility polymorphisms for nonsyndromic cleft lip with or without cleft palate in the Brazilian population.

scientific article published in January 2014

Anticancer properties of the fatty acid synthase inhibitor TVB-3166 on oral squamous cell carcinoma cell lines

scientific article published on 10 March 2020

Apoptosis caused by chemotherapeutic inhibition of nuclear factor-kappaB activation

scientific article published on 01 January 2003

Cleidocranial dysplasia: oral features and genetic analysis of 11 patients

article

Clinicopathological prognostic factors of oral tongue squamous cell carcinoma: a retrospective study of 202 cases

scientific article published on 28 February 2014

Clinicopathological significance of ubiquitin-specific protease 2a (USP2a), fatty acid synthase (FASN), and ErbB2 expression in oral squamous cell carcinomas

scientific article published on 9 April 2009

Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer

scientific article published in Nature Communications

Comparison between gingival and periodontal ligament fibroblasts from the same subject

scientific article

Contribution of polymorphisms in genes associated with craniofacial development to the risk of nonsyndromic cleft lip and/or palate in the Brazilian population.

scientific article published on May 2013

Cooverexpression of ERBB1 and ERBB4 receptors predicts poor clinical outcome in pN+ oral squamous cell carcinoma with extranodal spread.

scientific article

Cyclosporin A inhibits production and activity of matrix metalloproteinases by gingival fibroblasts

scientific article published on 01 February 2000

Cyclosporin A-induced gingival overgrowth is not associated with myofibroblast transdifferentiation.

scientific article

Detection and characterization of metalloproteinases with gelatinolytic, fibronectinolytic and fibrinogenolytic activities in brown spider (Loxosceles intermedia) venom.

scientific article published in July 1998

Differential expression of fatty acid synthase (FAS) and ErbB2 in nonmalignant and malignant oral keratinocytes.

scientific article

Effect of transforming growth factor-beta1, interleukin-6, and interferon-gamma on the expression of type I collagen, heat shock protein 47, matrix metalloproteinase (MMP)-1 and MMP-2 by fibroblasts from normal gingiva and hereditary gingival fibrom

scientific article published on 01 March 2003

Effects of fatty acid synthase inhibitors on lymphatic vessels: an in vitro and in vivo study in a melanoma model

scientific article published on 05 December 2016

ErbB receptors and fatty acid synthase expression in aggressive head and neck squamous cell carcinomas.

scientific article published on November 2010

ErbB2 and fatty acid synthase (FAS) expression in 102 squamous cell carcinomas of the tongue: correlation with clinical outcomes

scientific article published on 06 September 2007

Expression of PROX-1 in oral Kaposi's sarcoma spindle cells.

scientific article published on 13 June 2013

Expression of fatty acid synthase (FASN) in oral nevi and melanoma

scientific article published on 08 August 2011

Expression of fatty acid synthase, ErbB2 and Ki-67 in head and neck squamous cell carcinoma. A clinicopathological study.

scientific article

Expression of matrix metalloproteinases in cyclosporin-treated gingival fibroblasts is regulated by transforming growth factor (TGF)-beta1 autocrine stimulation.

scientific article published in November 2002

Extracellular vesicles derived from cancer-associated fibroblasts induce the migration and invasion of oral squamous cell carcinoma

scientific article published on 13 February 2019

FAS and ErbB2 expression in early local recurrent oral cancer.

scientific article

Fascin promotes migration and invasion and is a prognostic marker for oral squamous cell carcinoma.

scientific article published on 19 August 2017

Fatty acid synthase expression defines distinct molecular signatures in prostate cancer.

scientific article

Fatty acid synthase expression in squamous cell carcinoma of the tongue: clinicopathological findings

scientific article published on 01 May 2008

Fatty acid synthase inhibition with Orlistat promotes apoptosis and reduces cell growth and lymph node metastasis in a mouse melanoma model

scientific article published on December 2008

Fatty acid synthase inhibitors induce apoptosis in non-tumorigenic melan-a cells associated with inhibition of mitochondrial respiration

scientific article

Fatty acid synthase is required for the proliferation of human oral squamous carcinoma cells

scientific article

Gene and immunohistochemical expression of HIF-1α, GLUT-1, FASN, and adipophilin in carcinoma ex pleomorphic adenoma development

scientific article published on 16 March 2020

Goldenhar syndrome: clinical features with orofacial emphasis

scientific article published on December 2010

HOXA1 is overexpressed in oral squamous cell carcinomas and its expression is correlated with poor prognosis.

scientific article

HOXA10 controls proliferation, migration and invasion in oral squamous cell carcinoma.

scientific article published on April 2015

Hereditary gingival fibromatosis: a systematic review

scientific article

Hereditary gingival fibromatosis: report of a five-generation family using cellular proliferation analysis

scientific article published on 01 December 2005

Heterogeneous presence of myofibroblasts in hereditary gingival fibromatosis.

scientific article

Influence of VicRK and CovR on the interactions of Streptococcus mutans with phagocytes

scientific article published on 11 January 2012

Inhibition of fatty acid synthase in melanoma cells activates the intrinsic pathway of apoptosis.

scientific article published on 30 August 2010

Integrated proteomics identified up-regulated focal adhesion-mediated proteins in human squamous cell carcinoma in an orthotopic murine model

scientific article

Interactions between superoxide dismutase and paraoxonase polymorphic variants in nonsyndromic cleft lip with or without cleft palate in the Brazilian population

scientific article published on 21 September 2018

Intraneural perineurioma of the tongue: a case report

scientific article published on 01 July 2006

Intraoral acinic cell carcinoma: case report and review of the literature

scientific article published on November 1, 2008

Isolation and characterization of myofibroblast cell lines from oral squamous cell carcinoma.

scientific article

Lack of association between IRF6 polymorphisms (rs2235371 and rs642961) and non-syndromic cleft lip and/or palate in a Brazilian population.

scientific article published on 23 September 2009

Laminin and collagen IV distribution and ultrastructure of the basement membrane of the gingiva of the rat incisor.

scientific article published on September 1995

Laminin-induced PC-12 cell differentiation is inhibited following laser inactivation of cellular prion protein

scientific article published on 01 October 2000

Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor Prognosis

scientific article published on 28 August 2015

MTHFR rs2274976 polymorphism is a risk marker for nonsyndromic cleft lip with or without cleft palate in the Brazilian population.

scientific article

Matrix metalloproteinase-2 and -9 activities correlate with the disease-free survival of oral squamous cell carcinoma patients

scientific article published on January 1, 2002

Molecular events associated with ciclosporin A-induced gingival overgrowth are attenuated by Smad7 overexpression in fibroblasts.

scientific article published on 29 August 2011

Mutual paracrine effects of oral squamous cell carcinoma cells and normal oral fibroblasts: induction of fibroblast to myofibroblast transdifferentiation and modulation of tumor cell proliferation

scientific article published on 07 September 2007

Myofibroblasts in the stroma of oral cancer promote tumorigenesis via secretion of activin A

scientific article published on 02 July 2011

Myofibroblasts in the stroma of oral squamous cell carcinoma are associated with poor prognosis

scientific article published in December 2007

Myxoid calcified hamartoma and natal teeth: a case report

scientific article published on 22 October 2008

Normal inhibitory avoidance learning and anxiety, but increased locomotor activity in mice devoid of PrP(C)

scientific article (publication date: 25 August 1999)

Novel processed form of syndecan-1 shed from SCC-9 cells plays a role in cell migration

scientific article

Opposite effects of TGF-beta1 and IFN-gamma on transdifferentiation of myofibroblast in human gingival cell cultures

scientific article published on 02 April 2007

Oral paracoccidioidomycosis or squamous cell carcinoma?

scientific article published in January 2004

Oral paracoccidioidomycosis. A study of 36 South American patients

scientific article published on 01 April 1993

Ovariectomy reduces the gelatinolytic activity and expression of matrix metalloproteinases and collagen in rat molar extraction wounds

scientific article published on 04 November 2004

Overexpression of HOXB7 homeobox gene in oral cancer induces cellular proliferation and is associated with poor prognosis

scientific article

Polymorphisms at regions 1p22.1 (rs560426) and 8q24 (rs1530300) are risk markers for nonsyndromic cleft lip and/or palate in the Brazilian population

scientific article published on 26 March 2013

Polymorphisms in FGF12, VCL, CX43 and VAX1 in Brazilian patients with nonsyndromic cleft lip with or without cleft palate

scientific article

Polymorphisms in GABRB3 and oral clefting in the Brazilian population

scientific article published on 25 February 2013

Prognostic significance of cyclooxygenase 2 and phosphorylated Akt1 overexpression in primary nonmetastatic and metastatic cutaneous melanomas

scientific article published on 9 June 2017

Salivary gland tumors: immunohistochemical study of EGF, EGFR, ErbB-2, FAS and Ki-67

scientific article published on 01 October 2009

Sebaceous adenoma of oral cavity: report of case and comparative proliferation study with sebaceous gland hyperplasia and Fordyce's granules.

scientific article published in November 2003

Secretome profiling of oral squamous cell carcinoma-associated fibroblasts reveals organization and disassembly of extracellular matrix and collagen metabolic process signatures.

scientific article published on 13 January 2016

Sensitive assays for detection of lung cancer. Molecular markers in blood samples

scientific article published on 01 January 2003

Sialolithiasis of minor salivary glands: a clinical and histopathological study

scientific article published on 01 July 2005

Smad7 blocks transforming growth factor-β1-induced gingival fibroblast-myofibroblast transition via inhibitory regulation of Smad2 and connective tissue growth factor

scientific article published on 08 November 2010

Stanniocalcin 2 contributes to aggressiveness and is a prognostic marker for oral squamous cell carcinoma

scientific article published on 20 May 2020

The antimetastatic activity of orlistat is accompanied by an antitumoral immune response in mouse melanoma

scientific article published on 20 December 2019

The effect of cyclosporin A on the activity of matrix metalloproteinases during the healing of rat molar extraction wounds.

scientific article published in September 2001

The fatty acid synthase inhibitor orlistat reduces experimental metastases and angiogenesis in B16-F10 melanomas ⬇️

scientific article published on August 14, 2012

The fatty acid synthase inhibitor orlistat reduces the growth and metastasis of orthotopic tongue oral squamous cell carcinomas.

scientific article published on 20 December 2013

The influence of enamel matrix derivative associated with insulin-like growth factor-I on periodontal ligament fibroblasts

scientific article published in April 2004

The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer

scientific article

Transforming growth factor-beta1 autocrine stimulation regulates fibroblast proliferation in hereditary gingival fibromatosis.

scientific article published in December 2001

Use of TCA as a decalcifying agent for laminin immunohistochemistry

scientific article published on 01 October 1995

Visualizing inhibition of fatty acid synthase through mass spectrometric analysis of mitochondria from melanoma cells

scientific article published on February 2011

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