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List of works by Juan C Montero

Achilles' heel of triple negative cancer

scientific article

Activation of ErbB2 by overexpression or by transmembrane neuregulin results in differential signaling and sensitivity to herceptin

scientific article

Antitumor activity of the novel multi-kinase inhibitor EC-70124 in triple negative breast cancer

scientific article

Antitumoral activity of the mithralog EC-8042 in triple negative breast cancer linked to cell cycle arrest in G2

scientific article published on 30 September 2015

Breast cancer dissemination promoted by a neuregulin-collagenase 3 signalling node.

scientific article

CM363, a novel naphthoquinone derivative which acts as multikinase modulator and overcomes imatinib resistance in chronic myelogenous leukemia

scientific article

Cleavage of the TrkA neurotrophin receptor by multiple metalloproteases generates signalling-competent truncated forms

scientific article published on 01 April 1999

Differential shedding of transmembrane neuregulin isoforms by the tumor necrosis factor-alpha-converting enzyme

scientific article published on 01 November 2000

Erk5 is activated and acts as a survival factor in mitosis.

scientific article

Erratum: Achilles' heel of triple negative cancer

scientific article published on 13 December 2014

Expression of Erk5 in early stage breast cancer and association with disease free survival identifies this kinase as a potential therapeutic target

scientific article published on 15 May 2009

Expression of c-Kit isoforms in multiple myeloma: differences in signaling and drug sensitivity.

scientific article

Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.

scientific article

Identification of therapeutic targets in ovarian cancer through active tyrosine kinase profiling

scientific article published on 13 August 2015

In Silico Analysis Guides Selection of BET Inhibitors for Triple-Negative Breast Cancer Treatment.

scientific article

In vivo murine model of acquired resistance in myeloma reveals differential mechanisms for lenalidomide and pomalidomide in combination with dexamethasone.

scientific article

Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors.

scientific article published on 13 June 2011

Mitogen-activated protein kinase-dependent and -independent routes control shedding of transmembrane growth factors through multiple secretases.

scientific article published on April 2002

Mitotic arrest induced by a novel family of DNA topoisomerase II inhibitors.

scientific article

Molecular pathways: P-Rex in cancer.

scientific article published on 10 June 2013

Multifunctional role of Erk5 in multiple myeloma

scientific article published on 3 February 2005

Multisite phosphorylation of P-Rex1 by protein kinase C.

scientific article published on 24 October 2016

N-terminal cleavage of proTGFalpha occurs at the cell surface by a TACE-independent activity.

scientific article published on July 2005

Neuregulin expression in solid tumors: prognostic value and predictive role to anti-HER3 therapies

scientific article published on 08 April 2016

Neuregulin expression modulates clinical response to trastuzumab in patients with metastatic breast cancer

scientific article published on 01 July 2007

Neuregulins and cancer.

scientific article published on June 2008

P-Rex1 participates in Neuregulin-ErbB signal transduction and its expression correlates with patient outcome in breast cancer.

scientific article

PDCD4 limits prooncogenic neuregulin-ErbB signaling

scientific article published on 17 August 2020

Phospho-kinase profile of colorectal tumors guides in the selection of multi-kinase inhibitors.

scientific article published on 22 September 2015

Phospho-kinase profile of triple negative breast cancer and androgen receptor signaling.

scientific article

Phosphorylation of P-Rex1 at serine 1169 participates in IGF-1R signaling in breast cancer cells.

scientific article published on 27 July 2013

Regulation of the prometastatic neuregulin-MMP13 axis by SRC family kinases: therapeutic implications.

scientific article published on 15 October 2017

Surfaceome analyses uncover CD98hc as an antibody drug-conjugate target in triple negative breast cancer

scientific article published on 22 March 2022

Synthetic lethality interaction between Aurora kinases and CHEK1 inhibitors in ovarian cancer.

scientific article published on 28 August 2017

Targeting basal-like breast tumors with bromodomain and extraterminal domain (BET) and polo-like kinase inhibitors

scientific article published on 3 January 2017

Targeting the EGF/HER Ligand-Receptor System in Cancer.

scientific article

The extracellular linker of pro-neuregulin-alpha2c is required for efficient sorting and juxtacrine function.

scientific article published on 15 November 2006

The immunoglobulin-like domain of neuregulins potentiates ErbB3/HER3 activation and cellular proliferation.

scientific article published on 14 May 2018

The insulin-like growth factor-I receptor inhibitor NVP-AEW541 provokes cell cycle arrest and apoptosis in multiple myeloma cells.

scientific article published on 12 March 2008

Transautocrine signaling by membrane neuregulins requires cell surface targeting, which is controlled by multiple domains

scientific article

Transcriptomic profile induced in bone marrow mesenchymal stromal cells after interaction with multiple myeloma cells: implications in myeloma progression and myeloma bone disease

scientific article published on September 2014

Transforming growth factor-beta1 induces collagen synthesis and accumulation via p38 mitogen-activated protein kinase (MAPK) pathway in cultured L(6)E(9) myoblasts

scientific article published on 01 February 2002

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