List of works - Marco Rusnati

A CXCR1 haplotype hampers HIV-1 matrix protein p17 biological activity

scientific article published on October 2014

A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6

scientific article

A natural HIV p17 protein variant up-regulates the LMP-1 EBV oncoprotein and promotes the growth of EBV-infected B-lymphocytes: implications for EBV-driven lymphomagenesis in the HIV setting.

scientific article

Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands.

scientific article published on 18 August 2015

Alterations of blood vessel development by endothelial cells overexpressing fibroblast growth factor-2.

scientific article published on December 1999

Angiogenic growth factors interactome and drug discovery: The contribution of surface plasmon resonance.

scientific article

Antiangiogenic activity of semisynthetic biotechnological heparins: low-molecular-weight-sulfated Escherichia coli K5 polysaccharide derivatives as fibroblast growth factor antagonists

scientific article

Basic fibroblast growth factor in human pheochromocytoma: A biochemical and immunohistochemical study

scientific article published on 01 January 1993

Basic fibroblast growth factor in ovulatory cycle and postmenopausal human endometrium

scientific article published on January 1990

Biological activity of substrate-bound basic fibroblast growth factor (FGF2): recruitment of FGF receptor-1 in endothelial cell adhesion contacts

scientific article

Biotechnological engineering of heparin/heparan sulphate: a novel area of multi-target drug discovery.

scientific article

Bridging the past and the future of virology: surface plasmon resonance as a powerful tool to investigate virus/host interactions.

scientific article

Cell membrane GM1 ganglioside is a functional coreceptor for fibroblast growth factor 2

scientific article

Characterization of a Mr 20,000 basic fibroblast growth factor-like protein secreted by normal and transformed fetal bovine aortic endothelial cells

scientific article published on February 1990

Characterization of a Mr 25,000 basic fibroblast growth factor form in adult, regenerating, and fetal rat liver

scientific article published on 01 November 1989

Chemically sulfated Escherichia coli K5 polysaccharide derivatives as extracellular HIV-1 Tat protein antagonists

scientific article published in June 2004

Chemoselective surface immobilization of proteins through a cleavable peptide

scientific article published on 11 August 2011

Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors.

scientific article published in May 2005

Critical role of gonadal hormones on the genotoxic activity of the hepatocarcinogen DL-ZAMI 1305

scientific article published on 01 September 1987

Cutting edge: proangiogenic properties of alternatively activated dendritic cells.

scientific article published in September 2005

Direct and allosteric inhibition of the FGF2/HSPGs/FGFR1 ternary complex formation by an antiangiogenic, thrombospondin-1-mimic small molecule

scientific article

Discovery of novel VX-809 hybrid derivatives as F508del-CFTR correctors by molecular modeling, chemical synthesis and biological assays

scientific article published on 12 September 2020

Endogenous Basic Fibroblast Growth Factor Is Implicated in the Vascularization of the Chick Embryo Chorioallantoic Membrane ⬇️

scientific article published on July 1, 1995

Estro-progestinic replacement therapy modulates the levels of basic fibroblast growth factor (bFGF) in postmenopausal endometrium

scientific article published on 01 January 1993

Exploiting Surface Plasmon Resonance (SPR) Technology for the Identification of Fibroblast Growth Factor-2 (FGF2) Antagonists Endowed with Antiangiogenic Activity.

scientific article published on 20 August 2009

Fibroblast growth factor-2 antagonist and antiangiogenic activity of long-pentraxin 3-derived synthetic peptides.

scientific article published on January 2009

Fibroblast growth factor-2 binding to the thrombospondin-1 type III repeats, a novel antiangiogenic domain

scientific article

Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis

scientific article

Fibroblast growth factors and their receptors in hematopoiesis and hematological tumors

scientific article

Fibroblast growth factors/fibroblast growth factor receptors as targets for the development of anti-angiogenesis strategies

scientific article published on January 2007

HIV-1 Tat and heparan sulfate proteoglycan interaction: a novel mechanism of lymphocyte adhesion and migration across the endothelium

scientific article

HIV-1 Tat protein and endothelium: from protein/cell interaction to AIDS-associated pathologies.

scientific article

HIV-1 matrix protein p17 binds to the IL-8 receptor CXCR1 and shows IL-8-like chemokine activity on monocytes through Rho/ROCK activation.

scientific article published on 18 January 2012

HIV-1 matrix protein p17 promotes angiogenesis via chemokine receptors CXCR1 and CXCR2.

scientific article

Heparan sulfate proteoglycans mediate the angiogenic activity of the vascular endothelial growth factor receptor-2 agonist gremlin.

scientific article published on 15 September 2011

Heparin and heparan sulfate proteoglycans promote HIV-1 p17 matrix protein oligomerization: computational, biochemical and biological implications

scientific article published on 31 October 2019

Heparin derivatives as angiogenesis inhibitors

scientific article

Heparin-mimicking sulfonic acid polymers as multitarget inhibitors of human immunodeficiency virus type 1 Tat and gp120 proteins

scientific article published on 23 April 2007

Heparin/Heparan sulfate proteoglycans glycomic interactome in angiogenesis: biological implications and therapeutical use.

scientific article published on 10 April 2015

High molecular weight immunoreactive basic fibroblast growth factor-like proteins in rat pituitary and brain

scientific article published in August 1988

Highly sulfated K5 Escherichia coli polysaccharide derivatives inhibit respiratory syncytial virus infectivity in cell lines and human tracheal-bronchial histocultures.

scientific article

Human lymphoblastoid cells produce extracellular matrix-degrading enzymes and induce endothelial cell proliferation, migration, morphogenesis, and angiogenesis.

scientific article published on January 1998

Identification of a dendrimeric heparan sulfate-binding peptide that inhibits infectivity of genital types of human papillomaviruses.

scientific article

Identification of amino acid residues critical for the B cell growth-promoting activity of HIV-1 matrix protein p17 variants

scientific article published on 21 September 2018

Identification of an antiangiogenic FGF2-binding site in the N terminus of the soluble pattern recognition receptor PTX3.

scientific article published on 12 June 2006

Inhibition of Eph/ephrin interaction with the small molecule UniPR500 improves glucose tolerance in healthy and insulin-resistant mice

scientific article published on 06 January 2019

Inhibition of human respiratory syncytial virus infectivity by a dendrimeric heparan sulfate-binding peptide.

scientific article

Inhibition of intra- and extra-cellular Tat function and HIV expression by pertussis toxin B-oligomer.

scientific article published in February 2004

Integrin alphavbeta3 as a target for blocking HIV-1 Tat-induced endothelial cell activation in vitro and angiogenesis in vivo.

scientific article published on 15 September 2005

Interaction of HIV-1 Tat protein with heparin. Role of the backbone structure, sulfation, and size

scientific article (publication date: 25 April 1997)

Interaction of angiogenic basic fibroblast growth factor with endothelial cell heparan sulfate proteoglycans. Biological implications in neovascularization.

scientific article

Membrane association of peroxiredoxin-2 in red cells is mediated by the N-terminal cytoplasmic domain of band 3.

scientific article

Molecular interaction studies of HIV-1 matrix protein p17 and heparin: identification of the heparin-binding motif of p17 as a target for the development of multitarget antagonists

scientific article published on 19 November 2012

Multiple interactions of HIV-I Tat protein with size-defined heparin oligosaccharides

scientific article (publication date: October 1999)

Multispot, label-free biodetection at a phantom plastic-water interface

scientific article

Non-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors: an integrated strategy for the development of new antiangiogenic compounds

scientific article

Pentraxin 3 inhibits fibroblast growth factor 2-dependent activation of smooth muscle cells in vitro and neointima formation in vivo

scientific article published on 14 July 2005

Peptide-derivatized SB105-A10 dendrimer inhibits the infectivity of R5 and X4 HIV-1 strains in primary PBMCs and cervicovaginal histocultures

scientific article

Polyanionic drugs and viral oncogenesis: a novel approach to control infection, tumor-associated inflammation and angiogenesis.

scientific article

Polysulfated/sulfonated compounds for the development of drugs at the crossroad of viral infection and oncogenesis.

scientific article published on January 2009

Positively charged peptides can interact with each other, as revealed by solid phase binding assays

scientific article published on 20 March 2006

Pradimicin A, a carbohydrate-binding nonpeptidic lead compound for treatment of infections with viruses with highly glycosylated envelopes, such as human immunodeficiency virus

scientific article published on 18 October 2006

Purification of basic fibroblast growth factor from rat brain: identification of a Mr 22,000 immunoreactive form

scientific article published on September 1988

Recent Strategic Advances in CFTR Drug Discovery: An Overview

scientific article published on 31 March 2020

Role of the soluble pattern recognition receptor PTX3 in vascular biology

scientific article published on July 2007

Selective recognition of fibroblast growth factor-2 by the long pentraxin PTX3 inhibits angiogenesis

scientific article published on 18 March 2004

Short heparin sequences spaced by glycol-split uronate residues are antagonists of fibroblast growth factor 2 and angiogenesis inhibitors

scientific article

Sialic acid as a target for the development of novel antiangiogenic strategies

scientific article published on 12 December 2018

Sialic acid associated with αvβ3 integrin mediates HIV-1 Tat protein interaction and endothelial cell proangiogenic activation.

scientific article

Simian immunodeficiency virus and human immunodeficiency virus type 1 matrix proteins specify different capabilities to modulate B cell growth

scientific article

Speeding Up the Identification of Cystic Fibrosis Transmembrane Conductance Regulator-Targeted Drugs: An Approach Based on Bioinformatics Strategies and Surface Plasmon Resonance.

scientific article published on 8 January 2018

Structure-function relationship of basic fibroblast growth factor: site-directed mutagenesis of a putative heparin-binding and receptor-binding region

scientific article

Subcellular localization and biological activity of M(r) 18,000 basic fibroblast growth factor: site-directed mutagenesis of a putative nuclear translocation sequence.

scientific article published on January 1993

Substrate-immobilized HIV-1 Tat drives VEGFR2/α(v)β(3)-integrin complex formation and polarization in endothelial cells

scientific article

Sulfated K5 Escherichia coli polysaccharide derivatives as wide-range inhibitors of genital types of human papillomavirus.

scientific article published on 4 February 2008

The agmatine-containing poly(amidoamine) polymer AGMA1 binds cell surface heparan sulfates and prevents attachment of mucosal human papillomaviruses

scientific article

The binding of heparin to spike glycoprotein inhibits SARS-CoV-2 infection by three mechanisms

scientific article

The discovery of basic fibroblast growth factor/fibroblast growth factor-2 and its role in haematological malignancies.

scientific article

The fd phage and a peptide derived from its p8 coat protein interact with the HIV-1 Tat-NLS and inhibit its biological functions.

scientific article

Thrombospondin 1 as a scavenger for matrix-associated fibroblast growth factor 2

scientific article published on 28 August 2003

Thrombospondin-1 as a Paradigm for the Development of Antiangiogenic Agents Endowed with Multiple Mechanisms of Action.

scientific article

Thrombospondin-1 inhibits Kaposi's sarcoma (KS) cell and HIV-1 Tat-induced angiogenesis and is poorly expressed in KS lesions

article

Undersulfated and glycol-split heparins endowed with antiangiogenic activity

scientific article published in February 2004

Undersulfated, low-molecular-weight glycol-split heparin as an antiangiogenic VEGF antagonist

scientific article published on 20 October 2004

Urokinase-Type Plasminogen Activator Overexpression Enhances the Invasive Capacity of Endothelial Cells ⬇️

scientific article published on May 1, 1997

alpha(v)beta3-integrin-dependent activation of focal adhesion kinase mediates NF-kappaB activation and motogenic activity by HIV-1 Tat in endothelial cells

scientific article published on 16 August 2005

List of works by Marco Rusnati

A CXCR1 haplotype hampers HIV-1 matrix protein p17 biological activity

A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6

A natural HIV p17 protein variant up-regulates the LMP-1 EBV oncoprotein and promotes the growth of EBV-infected B-lymphocytes: implications for EBV-driven lymphomagenesis in the HIV setting.

Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands.

Alterations of blood vessel development by endothelial cells overexpressing fibroblast growth factor-2.

Angiogenic growth factors interactome and drug discovery: The contribution of surface plasmon resonance.

Antiangiogenic activity of semisynthetic biotechnological heparins: low-molecular-weight-sulfated Escherichia coli K5 polysaccharide derivatives as fibroblast growth factor antagonists

Basic fibroblast growth factor in human pheochromocytoma: A biochemical and immunohistochemical study

Basic fibroblast growth factor in ovulatory cycle and postmenopausal human endometrium

Biological activity of substrate-bound basic fibroblast growth factor (FGF2): recruitment of FGF receptor-1 in endothelial cell adhesion contacts

Biotechnological engineering of heparin/heparan sulphate: a novel area of multi-target drug discovery.

Bridging the past and the future of virology: surface plasmon resonance as a powerful tool to investigate virus/host interactions.

Cell membrane GM1 ganglioside is a functional coreceptor for fibroblast growth factor 2

Characterization of a Mr 20,000 basic fibroblast growth factor-like protein secreted by normal and transformed fetal bovine aortic endothelial cells

Characterization of a Mr 25,000 basic fibroblast growth factor form in adult, regenerating, and fetal rat liver

Chemically sulfated Escherichia coli K5 polysaccharide derivatives as extracellular HIV-1 Tat protein antagonists

Chemoselective surface immobilization of proteins through a cleavable peptide

Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors.

Critical role of gonadal hormones on the genotoxic activity of the hepatocarcinogen DL-ZAMI 1305

Cutting edge: proangiogenic properties of alternatively activated dendritic cells.

Direct and allosteric inhibition of the FGF2/HSPGs/FGFR1 ternary complex formation by an antiangiogenic, thrombospondin-1-mimic small molecule

Discovery of novel VX-809 hybrid derivatives as F508del-CFTR correctors by molecular modeling, chemical synthesis and biological assays

Endogenous Basic Fibroblast Growth Factor Is Implicated in the Vascularization of the Chick Embryo Chorioallantoic Membrane ⬇️

Estro-progestinic replacement therapy modulates the levels of basic fibroblast growth factor (bFGF) in postmenopausal endometrium

Exploiting Surface Plasmon Resonance (SPR) Technology for the Identification of Fibroblast Growth Factor-2 (FGF2) Antagonists Endowed with Antiangiogenic Activity.

Fibroblast growth factor-2 antagonist and antiangiogenic activity of long-pentraxin 3-derived synthetic peptides.

Fibroblast growth factor-2 binding to the thrombospondin-1 type III repeats, a novel antiangiogenic domain

Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis

Fibroblast growth factors and their receptors in hematopoiesis and hematological tumors

Fibroblast growth factors/fibroblast growth factor receptors as targets for the development of anti-angiogenesis strategies

HIV-1 Tat and heparan sulfate proteoglycan interaction: a novel mechanism of lymphocyte adhesion and migration across the endothelium

HIV-1 Tat protein and endothelium: from protein/cell interaction to AIDS-associated pathologies.

HIV-1 matrix protein p17 binds to the IL-8 receptor CXCR1 and shows IL-8-like chemokine activity on monocytes through Rho/ROCK activation.

HIV-1 matrix protein p17 promotes angiogenesis via chemokine receptors CXCR1 and CXCR2.

Heparan sulfate proteoglycans mediate the angiogenic activity of the vascular endothelial growth factor receptor-2 agonist gremlin.

Heparin and heparan sulfate proteoglycans promote HIV-1 p17 matrix protein oligomerization: computational, biochemical and biological implications

Heparin derivatives as angiogenesis inhibitors

Heparin-mimicking sulfonic acid polymers as multitarget inhibitors of human immunodeficiency virus type 1 Tat and gp120 proteins

Heparin/Heparan sulfate proteoglycans glycomic interactome in angiogenesis: biological implications and therapeutical use.

High molecular weight immunoreactive basic fibroblast growth factor-like proteins in rat pituitary and brain

Highly sulfated K5 Escherichia coli polysaccharide derivatives inhibit respiratory syncytial virus infectivity in cell lines and human tracheal-bronchial histocultures.

Human lymphoblastoid cells produce extracellular matrix-degrading enzymes and induce endothelial cell proliferation, migration, morphogenesis, and angiogenesis.

Identification of a dendrimeric heparan sulfate-binding peptide that inhibits infectivity of genital types of human papillomaviruses.

Identification of amino acid residues critical for the B cell growth-promoting activity of HIV-1 matrix protein p17 variants

Identification of an antiangiogenic FGF2-binding site in the N terminus of the soluble pattern recognition receptor PTX3.

Inhibition of Eph/ephrin interaction with the small molecule UniPR500 improves glucose tolerance in healthy and insulin-resistant mice

Inhibition of human respiratory syncytial virus infectivity by a dendrimeric heparan sulfate-binding peptide.

Inhibition of intra- and extra-cellular Tat function and HIV expression by pertussis toxin B-oligomer.

Integrin alphavbeta3 as a target for blocking HIV-1 Tat-induced endothelial cell activation in vitro and angiogenesis in vivo.

Interaction of HIV-1 Tat protein with heparin. Role of the backbone structure, sulfation, and size

Interaction of angiogenic basic fibroblast growth factor with endothelial cell heparan sulfate proteoglycans. Biological implications in neovascularization.

Membrane association of peroxiredoxin-2 in red cells is mediated by the N-terminal cytoplasmic domain of band 3.

Molecular interaction studies of HIV-1 matrix protein p17 and heparin: identification of the heparin-binding motif of p17 as a target for the development of multitarget antagonists

Multiple interactions of HIV-I Tat protein with size-defined heparin oligosaccharides

Multispot, label-free biodetection at a phantom plastic-water interface

Non-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors: an integrated strategy for the development of new antiangiogenic compounds

Pentraxin 3 inhibits fibroblast growth factor 2-dependent activation of smooth muscle cells in vitro and neointima formation in vivo

Peptide-derivatized SB105-A10 dendrimer inhibits the infectivity of R5 and X4 HIV-1 strains in primary PBMCs and cervicovaginal histocultures

Polyanionic drugs and viral oncogenesis: a novel approach to control infection, tumor-associated inflammation and angiogenesis.

Polysulfated/sulfonated compounds for the development of drugs at the crossroad of viral infection and oncogenesis.

Positively charged peptides can interact with each other, as revealed by solid phase binding assays

Pradimicin A, a carbohydrate-binding nonpeptidic lead compound for treatment of infections with viruses with highly glycosylated envelopes, such as human immunodeficiency virus

Purification of basic fibroblast growth factor from rat brain: identification of a Mr 22,000 immunoreactive form

Recent Strategic Advances in CFTR Drug Discovery: An Overview

Role of the soluble pattern recognition receptor PTX3 in vascular biology

Selective recognition of fibroblast growth factor-2 by the long pentraxin PTX3 inhibits angiogenesis

Short heparin sequences spaced by glycol-split uronate residues are antagonists of fibroblast growth factor 2 and angiogenesis inhibitors

Sialic acid as a target for the development of novel antiangiogenic strategies

Sialic acid associated with αvβ3 integrin mediates HIV-1 Tat protein interaction and endothelial cell proangiogenic activation.

Simian immunodeficiency virus and human immunodeficiency virus type 1 matrix proteins specify different capabilities to modulate B cell growth

Speeding Up the Identification of Cystic Fibrosis Transmembrane Conductance Regulator-Targeted Drugs: An Approach Based on Bioinformatics Strategies and Surface Plasmon Resonance.

Structure-function relationship of basic fibroblast growth factor: site-directed mutagenesis of a putative heparin-binding and receptor-binding region

Subcellular localization and biological activity of M(r) 18,000 basic fibroblast growth factor: site-directed mutagenesis of a putative nuclear translocation sequence.

Substrate-immobilized HIV-1 Tat drives VEGFR2/α(v)β(3)-integrin complex formation and polarization in endothelial cells

Sulfated K5 Escherichia coli polysaccharide derivatives as wide-range inhibitors of genital types of human papillomavirus.

The agmatine-containing poly(amidoamine) polymer AGMA1 binds cell surface heparan sulfates and prevents attachment of mucosal human papillomaviruses

The binding of heparin to spike glycoprotein inhibits SARS-CoV-2 infection by three mechanisms

The discovery of basic fibroblast growth factor/fibroblast growth factor-2 and its role in haematological malignancies.

The fd phage and a peptide derived from its p8 coat protein interact with the HIV-1 Tat-NLS and inhibit its biological functions.