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List of works by Nobuyuki Matoba

A mucosally targeted subunit vaccine candidate eliciting HIV-1 transcytosis-blocking Abs.

scholarly article

A novel anti-HIV-1 bispecific bNAb-lectin fusion protein engineered in a plant-based transient expression system

scientific article published on 12 March 2019

A novel anti-hypertensive peptide derived from ovalbumin induces nitric oxide-mediated vasorelaxation in an isolated SHR mesenteric artery

scientific article published on 01 June 1999

Bioactive peptides derived from food proteins preventing lifestyle-related diseases

scientific article published on 01 January 2000

Biochemical and immunological characterization of the plant-derived candidate human immunodeficiency virus type 1 mucosal vaccine CTB-MPR.

scientific article

Biological and biochemical characterization of HIV‐1 Gag/dgp41 virus‐like particles expressed in Nicotiana benthamiana ⬇️

scientific article published on March 19, 2013

Bulk production of the antiviral lectin griffithsin

scientific article

Cancer biologics made in plants

scientific article published on 27 November 2019

Cholera toxin B: one subunit with many pharmaceutical applications

scientific article

Co-expression of human calreticulin significantly improves the production of HIV gp140 and other viral glycoproteins in plants

scientific article published on 24 February 2020

Design and production of genetically modified soybean protein with anti-hypertensive activity by incorporating potent analogue of ovokinin(2-7).

scientific article published in May 2001

Design of a genetically modified soybean protein preventing hypertension based on an anti-hypertensive peptide derived from ovalbumin

scientific article published on 01 June 2003

Design of a highly potent anti-hypertensive peptide based on ovokinin(2-7)

scientific article published on 01 June 2002

Designing potent derivatives of ovokinin(2-7), an anti-hypertensive peptide derived from ovalbumin

scientific article published on 01 March 2001

Effect of temperature post viral vector inoculation on the amount of hemagglutinin transiently expressed in Nicotiana benthamiana leaves.

scientific article published on 28 April 2017

Effects of plant density on recombinant hemagglutinin yields in an Agrobacterium-mediated transient gene expression system using Nicotiana benthamiana plants.

scientific article published on April 2017

Efficient single tobamoviral vector-based bioproduction of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 in Nicotiana benthamiana plants and utility of VRC01 in combination microbicides

scientific article published on 12 February 2013

Engineering of a Lectibody Targeting High-Mannose-Type Glycans of the HIV Envelope

scientific article published on 09 August 2019

Environment Control to Improve Recombinant Protein Yields in Plants Based on Agrobacterium-Mediated Transient Gene Expression

scientific article

Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1.

scientific article

Facile Method for the Production of Recombinant Cholera Toxin B Subunit in E. coli.

scientific article published in January 2016

Griffithsin-Modified Electrospun Fibers as a Delivery Scaffold To Prevent HIV Infection.

scientific article published on 22 August 2016

HIV-1 neutralization profile and plant-based recombinant expression of actinohivin, an Env glycan-specific lectin devoid of T-cell mitogenic activity

scientific article published in 2010

Humoral immune responses by prime-boost heterologous route immunizations with CTB-MPR(649-684), a mucosal subunit HIV/AIDS vaccine candidate

scientific article

Humoral immunogenicity of an HIV-1 envelope residue 649–684 membrane-proximal region peptide fused to the plague antigen F1-V ⬇️

scientific article published on July 13, 2011

Hydroponic Treatment of Nicotiana benthamiana with Kifunensine Modifies the N-glycans of Recombinant Glycoprotein Antigens to Predominantly Man9 High-Mannose Type upon Transient Overexpression

scientific article published on 30 January 2018

Immunological Characterization of Plant-Based HIV-1 Gag/Dgp41 Virus-Like Particles

scientific article

Impact of Q-Griffithsin anti-HIV microbicide gel in non-human primates: In situ analyses of epithelial and immune cell markers in rectal mucosa

scientific article published on 02 December 2019

Impact of the griffithsin anti-HIV microbicide and placebo gels on the rectal mucosal proteome and microbiome in non-human primates.

scientific article published on 23 May 2018

Investigation of griffithsin's interactions with human cells confirms its outstanding safety and efficacy profile as a microbicide candidate

scientific article (publication date: 2011)

Metastasis of cholangiocarcinoma is promoted by extended high-mannose glycans

scientific article published on 25 March 2020

N-Glycosylation of Cholera Toxin B Subunit: Serendipity for Novel Plant-Made Vaccines?

scientific article published on 22 December 2015

N-glycosylation of cholera toxin B subunit in Nicotiana benthamiana: impacts on host stress response, production yield and vaccine potential.

scientific article

Oral administration of a recombinant cholera toxin B subunit promotes mucosal healing in the colon

scientific article published on 02 November 2016

P02-10. Plant expression of chimeric Gag/gp41 virus-like particles as a mucosally-targeted subunit vaccine against HIV-1.

scientific article

P12-16. Biochemical and immunological characterization of the plant-derived candidate HIV-1 mucosal vaccine CTB-MPR.

scientific article published on 22 October 2009

Production of Recombinant Cholera Toxin B Subunit in Nicotiana benthamiana Using GENEWARE® Tobacco Mosaic Virus Vector.

scientific article

Rapid and scalable plant-based production of a cholera toxin B subunit variant to aid in mass vaccination against cholera outbreaks

scientific article published in 2013

Rate of hepatitis C viral clearance by human livers in human patients: Liver transplantation modeling primary infection and implications for studying entry inhibition

scientific article

Removal of bacterial suspension water occupying the intercellular space of detached leaves after agroinfiltration improves the yield of recombinant hemagglutinin in a Nicotiana benthamiana transient gene expression system

scientific article

Repeated Oral Administration of a KDEL-tagged Recombinant Cholera Toxin B Subunit Effectively Mitigates DSS Colitis Despite a Robust Immunogenic Response

scientific article published on 20 November 2019

Safety and Efficacy of Avaren-Fc Lectibody Targeting HCV High-Mannose Glycans in a Human Liver Chimeric Mouse Model

scientific article published on 24 April 2020

Scalable Production of HPV16 L1 Protein and VLPs from Tobacco Leaves

scientific article

Therapeutic Potential of Cholera Toxin B Subunit for the Treatment of Inflammatory Diseases of the Mucosa

scientific article published on 23 November 2017

Transcytosis-blocking abs elicited by an oligomeric immunogen based on the membrane proximal region of HIV-1 gp41 target non-neutralizing epitopes.

scientific article published on May 2008

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