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List of works by Giuseppe Basso

17q21-qter trisomy is an indicator of poor prognosis in acute myelogenous leukemia

scientific article published on 01 January 2001

2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition

scientific article published on 5 December 2017

2-Arylamino-4-amino-5-aroylthiazoles. "One-pot" synthesis and biological evaluation of a new class of inhibitors of tubulin polymerization

scientific article published on September 2009

A Case of T-cell Acute Lymphoblastic Leukemia Relapsed As Myeloid Acute Leukemia

scientific article published on 03 May 2016

A high definition picture of key genes and pathways mutated in pediatric follicular lymphoma

scientific article published on 28 February 2019

A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells.

scientific article published on 06 July 2011

A leukemia-enriched cDNA microarray platform identifies new transcripts with relevance to the biology of pediatric acute lymphoblastic leukemia.

scientific article

A mesenchymal chondrosarcoma of a child with the reciprocal translocation (11;22)(q24;q12)

scientific article published on 01 December 1993

A mixed-methods study of the disease experience in hematopoietic stem cell transplantation survivors: the contribution of text analysis

scientific article published on 10 September 2020

A novel copper(I) complex induces ER-stress-mediated apoptosis and sensitizes B-acute lymphoblastic leukemia cells to chemotherapeutic agents

scientific article

A single high dose of idarubicin combined with high-dose ARA-C for treatment of first relapse in childhood 'high-risk' acute lymphoblastic leukaemia: a study of the AIEOP group

scientific article published in September 2002

A synthetic BMP-2 mimicking peptide induces glioblastoma stem cell differentiation

scientific article

A therapeutic approach to treat prostate cancer by targeting Nm23-H1/h-Prune interaction

scientific article published on 20 August 2014

A three-miRNA-based expression signature at diagnosis can predict occurrence of relapse in children with t(8;21) RUNX1-RUNX1T1 acute myeloid leukaemia

scientific article published on 29 September 2017

AIEOP-BFM consensus guidelines 2016 for flow cytometric immunophenotyping of Pediatric acute lymphoblastic leukemia.

scientific article published on 10 February 2017

AKR1C enzymes sustain therapy resistance in paediatric T-ALL.

scientific article

ALK kinase domain mutations in primary anaplastic large cell lymphoma: consequences on NPM-ALK activity and sensitivity to tyrosine kinase inhibitors

scientific article

Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder

scientific article published in May 2003

Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.

scientific article

Active and late rosette-forming cells: immunological and cytochemical characterization

scientific article published on 01 November 1981

Acute Leukemia of Ambiguous Lineage: A Comprehensive Survival Analysis Enables Designing New Treatment Strategies ⬇️

scholarly article

Acute Lymphoblastic Leukemia in Children with Down Syndrome: A Report From the Ponte Di Legno Study Group, ⬇️

scholarly article

Acute differentiated dendritic cell leukemia: a variant form of pediatric acute myeloid leukemia with MLL translocation

scientific article published on 04 January 2007

Acute leukemia subclassification: a marker protein expression perspective

scientific article published on June 2004

Acute lymphoblastic leukemia and Down syndrome: presenting features and treatment outcome in the experience of the Italian Association of Pediatric Hematology and Oncology (AIEOP)

scientific article published on 01 August 2008

Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group

scientific article

Adolescent and young adult cancer survivors narrate their stories: Predictive model of their personal growth and their follow-up acceptance

scientific article published on 22 September 2018

Advanced pediatric myelodysplastic syndromes: can immunophenotypic characterization of blast cells be a diagnostic and prognostic tool?

scientific article published on 01 March 2009

Altered mRNA expression of PAX5 is a common event in acute lymphoblastic leukaemia.

scientific article

Amplified segment in the 'Down syndrome critical region' on HSA21 shared between Down syndrome and euploid AML-M0 excludes RUNX1, ERG and ETS2

scientific article published on 05 January 2012

An Extensive Quality Control and Quality Assurance (QC/QA) Program Significantly Improves Inter-Laboratory Concordance Rates of Flow-Cytometric Minimal Residual Disease Assessment in Acute Lymphoblastic Leukemia: An I-BFM-FLOW-Network Report

scientific article published on 6 December 2021

An international standardization programme towards the application of gene expression profiling in routine leukaemia diagnostics: the Microarray Innovations in LEukemia study prephase.

scientific article published on September 2008

Analysis of CDKN2A, CDKN2B, CDKN2C, and cyclin Ds gene status in hepatoblastoma

scientific article

Analysis of cyclin-dependent kinase inhibitor genes (CDKN2A, CDKN2B, andCDKN2C) in childhood rhabdomyosarcoma

article

Annexin 2A sustains glioblastoma cell dissemination and proliferation

scientific article published on 13 July 2016

Antileukemic Efficacy of BET Inhibitor in a Preclinical Mouse Model of MLL-AF4 Infant ALL

scientific article published on 10 May 2018

Antithrombin Plasma Levels and Fibtem Determination in Children with Acute Lymphoblastic Leukemia Undergoing Asparaginase Treatment ⬇️

scholarly article

Apoptosis and phosphatidylserine-mediated recognition during the take-over phase of the colonial life-cycle in the ascidian Botryllus schlosseri

scientific article published on 23 May 2003

Are all cases of paediatric essential thrombocythaemia really myeloproliferative neoplasms? Analysis of a large cohort.

scientific article

Are genotypes of glutathione S-transferase superfamily a risk factor for childhood acute lymphoblastic leukemia? Results of an Italian case-control study

scientific article published on 22 February 2007

Argininosuccinate lyase deficiency: mutational spectrum in Italian patients and identification of a novel ASL pseudogene.

scientific article

Association between a combination of single nucleotide polymorphisms and large vessel cerebral vasculopathy in African children with sickle cell disease.

scientific article published on 22 July 2016

Association of cytogenetic abnormalities with detection of BCR-ABL fusion transcripts in children with T-lineage lymphoproliferative diseases (T-ALL and T-NHL)

scientific article published on 01 March 2004

Attachment orientations and psychological adjustment of parents of children with cancer: A matched-group comparison

scientific article published in June 2017

Autosomal dominant macrothrombocytopenia with ineffective thrombopoiesis

scientific article published on 01 May 2002

BAG1 Overexpression Restrains the Anti-Apoptotic BCL2, MCL1 and HSP70 Proteins in Acute Myeloid Leukemia. ⬇️

scholarly article

BAG1: The Guardian of Anti-Apoptotic Proteins in Acute Myeloid Leukemia ⬇️

scientific article published on October 10, 2011

BMP9 counteracts the tumorigenic and pro-angiogenic potential of glioblastoma

scientific article published on 05 July 2018

Biological Features and Prognostic Impact of CRLF2 Overexpression In Childhood ALL ⬇️

scholarly article

Bone marrow ectopic expression of a non-coding RNA in childhood T-cell acute lymphoblastic leukemia with a novel t(2;11)(q11.2;p15.1) translocation

scientific article published on 23 October 2008

CBFA2T3-GLIS2 fusion transcript is a novel common feature in pediatric, cytogenetically normal AML, not restricted to FAB M7 subtype

scientific article published on 13 February 2013

CD11b is a therapy resistance- and minimal residual disease-specific marker in precursor B-cell acute lymphoblastic leukemia

scientific article published on 12 March 2010

CD20 up-regulation in pediatric B-cell precursor acute lymphoblastic leukemia during induction treatment: setting the stage for anti-CD20 directed immunotherapy

scientific article published on 09 September 2008

CD371 cell surface expression: a unique feature of DUX4-rearranged acute lymphoblastic leukemia

scientific article published on 31 January 2019

CD4(+) T regulatory cells are more resistant to DNA damage compared to CD4(+) T effector cells as revealed by flow cytometric analysis

scientific article published on 30 August 2011

CI-FISH, GEP, and SNPs Correlate Genomic Categories with Risk Stratification in Children with T-ALL. ⬇️

scholarly article

COX16 is required for assembly of cytochrome c oxidase in human cells and is involved in copper delivery to COX2.

scientific article published on 18 January 2018

CREB Controls C/Ebpd to Impair Myeloid Differentiation Process in Acute Myeloid Leukemia ⬇️

scholarly article

CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia

scientific article published on 15 July 2016

CTLA-4 is not restricted to the lymphoid cell lineage and can function as a target molecule for apoptosis induction of leukemic cells.

scientific article published on 15 August 2002

Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation

scientific article published on 15 September 2020

Cell Adhesion Molecule Expression in Cord Blood CD34 + Cells ⬇️

scientific article published on January 1, 1998

Central role of mitochondria and p53 in PUVA-induced apoptosis in human keratinocytes cell line NCTC-2544.

scientific article published on 11 October 2007

Cerebrospinal fluid analysis by 8-color flow cytometry in children with acute lymphoblastic leukemia

scientific article published on 25 April 2019

Characterization and transcription studies of a phytochelatin synthase gene from the solitary tunicate Ciona intestinalis exposed to cadmium.

scientific article

Characterization of lincRNA BALIR-6 in MLL rearranged B-lymphoblastic leukemia ⬇️

scholarly article

Characterization of two patients with lymphomas of large granular lymphocytes

scientific article published on 01 February 1984

Characterizing the Function of an RNA Binding Protein, IGF2BP3, in Hematopoiesis ⬇️

scholarly article

Chemokine receptor expression and function in childhood acute lymphoblastic leukemia of B-lineage

scientific article published on 22 August 2005

Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers.

scientific article

Childhood high-risk acute lymphoblastic leukemia in first remission: results after chemotherapy or transplant from the AIEOP ALL 2000 study

scientific article published on 10 January 2014

Children with Thalassemia Major Display Abnormal Renal Tubular Function ⬇️

scholarly article

Clinical and Biological Characterization of Children with FLT3ITD Mutated Acute Myeloid Leukemia (AML): A Report from the AIEOP AML-2002 Study Group ⬇️

scholarly article

Clinical features and outcome of SIL/TAL1-positive T-cell acute lymphoblastic leukemia in children and adolescents: a 10-year experience of the AIEOP group

scientific article published on 10 October 2014

Clinical impact of miR-223 expression in pediatric T-Cell lymphoblastic lymphoma.

scientific article published on 11 November 2017

Clinical relevance of DNA ploidy and proliferative activity in childhood rhabdomyosarcoma: a retrospective analysis of patients enrolled onto the Italian Cooperative Rhabdomyosarcoma Study RMS88

scientific article published on 01 March 1997

Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microarray Innovations in Leukemia Study Group

scientific article published on 20 April 2010

Clinico-biological features of 5202 patients with acute lymphoblastic leukemia enrolled in the Italian AIEOP and GIMEMA protocols and stratified in age cohorts

scientific article published on 28 May 2013

Clonal Evolution and Lack of BCR-ABL1 Mutations in Pediatric Ph+ ALL Patients Resistant/Refractory to Imatinib Treatment ⬇️

scholarly article

Clonal evolution mechanisms in NT5C2 mutant-relapsed acute lymphoblastic leukaemia

scientific article published on 17 January 2018

Clonal variegation and dynamic competition of leukemia-initiating cells in infant acute lymphoblastic leukemia with MLL rearrangement

article

Clonality profile in relapsed precursor-B-ALL children by GeneScan and sequencing analyses. Consequences on minimal residual disease monitoring

scientific article published on 01 August 2003

Coagulation activation in children with sickle cell disease is associated with cerebral small vessel vasculopathy

scientific article

Cognition and the Default Mode Network in Children with Sickle Cell Disease: A Resting State Functional MRI Study

scientific article

Cognitive evoked potentials and neural networks are abnormal in children with sickle cell disease and not related to the degree of anaemia, pain and silent infarcts.

scientific article published on 21 November 2014

Collaboration between Activating Mutations in JAK2 and Trisomy 21 in the Acute Lymphoblastic Leukemias of Down Syndrome (DS). ⬇️

scholarly article

Comparative genomic analysis of PML and RARA breakpoints in paired diagnosis/relapse samples of patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy

scientific article published on 24 August 2017

Comparative sequence analysis of incomplete DJH and TCR gene rearrangements in children with relapses of T-ALL

scientific article published on 01 September 2005

Comprehensive care for sickle cell disease immigrant patients: a reproducible model achieving high adherence to minimum standards of care.

scientific article published on 22 February 2012

Computational analysis of flow-cytometry antigen expression profiles in childhood acute lymphoblastic leukemia: an MLL/AF4 identification.

scientific article published in August 2003

Concise synthesis and biological evaluation of 2-Aroyl-5-amino benzo[b]thiophene derivatives as a novel class of potent antimitotic agents

scientific article

Convergent synthesis and biological evaluation of 2-amino-4-(3',4',5'-trimethoxyphenyl)-5-aryl thiazoles as microtubule targeting agents

scientific article

Copper and bezafibrate cooperate to rescue cytochrome c oxidase deficiency in cells of patients with SCO2 mutations

scientific article

Core Binding Factor Acute Myeloid Leukemia In Pediatric Patients Enrolled In The AIEOP AML 2002/01 Trial: The Impact Of Minimal Residual Disease On Patient Outcome ⬇️

scholarly article

Core-binding factor acute myeloid leukemia in pediatric patients enrolled in the AIEOP AML 2002/01 trial: screening and prognostic impact of c-KIT mutations.

scientific article

Correction to: LIN28B increases neural crest cell migration and leads to transformation of trunk sympathoadrenal precursors

scientific article published on 01 April 2020

Could Hemorrhagic and Thrombotic Risk Due to Peg-Asparaginase be Identified By Coagulative Tests Using Fibtem and Antithrombin Levels? A Single Centre Study ⬇️

scholarly article

Course of anti-ALK antibody titres during chemotherapy in children with anaplastic large cell lymphoma

scientific article

Cytogenetic analysis of hepatoblastoma: hypothesis of cytogenetic evolution in such tumors and results of a multicentric study

scientific article published on 01 July 1998

Cytogenetic t(11;17)(q13;q21) in a pediatric ependymoma. Is 11q13 a recurring breakpoint in ependymomas?

scientific article

Cytogenetics of pediatric central nervous system tumors

scientific article published in October 1996

Cytokeratins patterns in childhood primary liver tumors

scientific article published in January 1993

D cells with cytotoxic activity in acute lymphoblastic leukemia

scientific article published on 01 June 1980

DHH-RHEBL1 fusion transcript: a novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia

scientific article

DLX genes as targets of ALL-1: DLX 2,3,4 down-regulation in t(4;11) acute lymphoblastic leukemias

scientific article published in August 2003

DNA copy-number abnormalities do not occur in infant ALL with t(4;11)/MLL-AF4

scientific article published on 12 November 2009

DNA methyltransferase 3a hot-spot locus is not mutated in pediatric patients affected by acute myeloid or T-cell acute lymphoblastic leukemia: an Italian study

scientific article published on 31 August 2011

DNA variants in DHFR gene and response to treatment in children with childhood B ALL: revisited in AIEOP-BFM protocol.

scientific article published on 6 December 2017

Deciphering KRAS and NRAS mutated clone dynamics in MLL-AF4 paediatric leukaemia by ultra deep sequencing analysis

scientific article published on 04 October 2016

Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia

scientific article published on 05 May 2016

Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3',4',5'-Trimethoxyphenyl)-2-Aryl-1H-Imidazole

scientific article published on 24 May 2016

Design of a Comprehensive Fluorescence in Situ Hybridization Assay for Genetic Classification of T-Cell Acute Lymphoblastic Leukemia

scientific article published on 04 March 2020

Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents

scientific article

Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents.

scientific article

Design, synthesis and biological evaluation of arylcinnamide hybrid derivatives as novel anticancer agents

scientific article

Design, synthesis, and structure-activity relationships of azolylmethylpyrroloquinolines as nonsteroidal aromatase inhibitors

scientific article

Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1)

scientific article published on 31 March 2016

Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.

scientific article published on 26 March 2015

Detection and role of minimal disseminated disease in children with lymphoblastic lymphoma: The AIEOP experience.

scientific article

Detection of CALM-AF10 Fusion Transcript Does Not Predict A Poor Prognosis in Children with T-Lineage Acute Lymphoblastic Leukemia Treated with AIEOP ALL 2000 Protocol and Subsequent Modified 2000 Study (R-2006). ⬇️

scholarly article

Detection of PICALM-MLLT10 (CALM-AF10) and outcome in children with T-lineage acute lymphoblastic leukemia ⬇️

scientific article published on May 14, 2013

Detection of minimal residual disease in pediatric acute lymphoblastic leukemia

scientific article published on 26 June 2013

Detection of prognostic factors in children and adolescents with Burkitt and Diffuse Large B-Cell Lymphoma treated with the AIEOP LNH-97 protocol

scientific article published on 8 July 2016

Development of a pluripotent stem cell derived neuronal model to identify chemically induced pathway perturbations in relation to neurotoxicity: effects of CREB pathway inhibition

scientific article published on 19 August 2014

Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000.

scientific article published on 17 February 2016

Diagnosis and genetic subtypes of leukemia combining gene expression and flow cytometry

scientific article published on 27 June 2007

Diazoniapolycyclic ions inhibit the activity of topoisomerase I and the growth of certain tumor cell lines

scientific article published on November 2008

Diencephalic syndrome and disseminated juvenile pilocytic astrocytomas of the hypothalamic-optic chiasm region

scientific article published in July 1997

Differences in circulating microRNA signature in Prader-Willi syndrome and non-syndromic obesity

scientific article published on 01 December 2018

Differential expression of hERG1A and hERG1B genes in pediatric acute lymphoblastic leukemia identifies different prognostic subgroups.

scientific article published on 16 January 2014

Differential response of linear and angular psoralens in PUVA-induced apoptosis in HL-60 cells

scientific article published on 28 January 2004

Digital-Droplet PCR, an Accurate Method for IG/TR PCR-MRD Stratification in Childhood Acute Lymphoblastic Leukemia ⬇️

scholarly article

Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia

scientific article

Discovery and optimization of a series of 2-aryl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazoles as novel anticancer agents.

scientific article

Distribution of TP53 mutations among acute leukemias with MLL rearrangements

scientific article published on 01 January 1996

Dna Methylation Is Linked to a Specific Cell-Adhesion Program in Relapsed Pediatric t(8;21)(q22;q22)RUNX1-RUNX1T1 Patients ⬇️

scholarly article

Down-regulation of DLX3 expression in MLL-AF4 childhood lymphoblastic leukemias is mediated by promoter region hypermethylation.

scientific article

Dual inhibition of PI3K/mTOR signaling in chemoresistant AML primary cells

scientific article published on 19 March 2018

EB-3D a novel choline kinase inhibitor induces deregulation of the AMPK-mTOR pathway and apoptosis in leukemia T-cells

scientific article published on 11 July 2018

Early Relapse in ALL Is Identified by Time to Leukemia in NOD/SCID Mice and Is Characterized by a Gene Signature Involving Survival Pathways

article

Early T-cell precursor acute lymphoblastic leukaemia in children treated in AIEOP centres with AIEOP-BFM protocols: a retrospective analysis

scientific article published on 26 January 2016

Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia

scientific article

Early and rapid diagnosis of CMV infection by nonradioactive in situ hybridization in pediatric kidney transplant recipients

scientific article published on 01 January 1992

Effect of protracted high-dose L-asparaginase given as a second exposure in a Berlin-Frankfurt-Münster-based treatment: results of the randomized 9102 intermediate-risk childhood acute lymphoblastic leukemia study--a report from the Associazione Ita

scientific article published in March 2001

Eltrombopag use in a patient with Wiskott-Aldrich syndrome

scientific article

Epigenetic heterogeneity affects the risk of relapse in children with t(8;21)RUNX1-RUNX1T1-rearranged AML.

scientific article published on 2 February 2018

Evaluation of Minimal Residual Disease As a Surrogate Endpoint for Event Free Survival in Childhood B-Lineage Acute Lymphoblastic Leukemia ⬇️

scholarly article

Evaluation of Technical Issues in a Pilot Multicenter Newborn Screening Program for Sickle Cell Disease

scientific article published on 21 December 2018

Evolution of Sub-Clones with KRAS Mutations In Pediatric Patients with MLL-AF4 Rearrangements ⬇️

scholarly article

Ex Vivo Signaling Protein Mapping in T Lymphocytes in the Psoriatic Arthritis Joints.

scientific article

Ex vivo-expanded bone marrow CD34(+) for acute myocardial infarction treatment: in vitro and in vivo studies

scientific article

Exome sequencing identifies putative drivers of progression of transient myeloproliferative disorder to AMKL in infants with Down syndrome

scientific article published on 3 June 2013

Expression Level Of A Coagulation Factor Gene, F13A1 Defines Characteristic Subpopulations Of Childhood Acute Lymphoblastic Leukemia ⬇️

scholarly article

Expression and distribution of the adrenomedullin system in newborn human thymus.

scientific article

Expression and functional analysis of human leukocyte antigen class I antigen-processing machinery in medulloblastoma.

scientific article published on June 2007

Expression of CD58 in normal, regenerating and leukemic bone marrow B cells: implications for the detection of minimal residual disease in acute lymphocytic leukemia ⬇️

scientific article published on 01 November 2003

Expression of the immunoglobulin superfamily cell membrane adhesion molecule Cd146 in acute leukemia.

scientific article published on 23 June 2015

Extended intrathecal methotrexate may replace cranial irradiation for prevention of CNS relapse in children with intermediate-risk acute lymphoblastic leukemia treated with Berlin-Frankfurt-Münster-based intensive chemotherapy. The Associazione Ital

scientific article

Extensive Coagulation Profile in Children with Sickle Cell Disease and Its Role in Cerebral Micro-Vasculopathy ⬇️

scholarly article

FOXM1 is overexpressed in B-acute lymphoblastic leukemia (B-ALL) and its inhibition sensitizes B-ALL cells to chemotherapeutic drugs

scientific article

FOXO3a and Posttranslational Modifications Mediate Glucocorticoid Sensitivity in B-ALL.

scientific article published on 16 September 2015

Favorable Outcome of Children with Acute Megakaryoblastic Leukemia Treated with the AIEOP AML 2002/01 Protocol ⬇️

scholarly article

Favourable Outcome in Infants with Acute Myeloid Leukemia Treated with the AIEOP AML 2002/01 Protocol ⬇️

scholarly article

Features of Avascular Osteonecrosis in Children Treated for Acute Lymphoblastic Leukaemia: Experience in a Single Center ⬇️

scholarly article

Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis.

scientific article

Fine tuning of surface CRLF2 expression and its associated signaling profile in childhood B-cell precursor acute lymphoblastic leukemia.

scientific article published on 10 April 2015

Flow diagnostics essential code: a simple and brief format for the summary of leukemia phenotyping

scientific article published in July 2014

Flow-cytometric minimal residual disease monitoring in blood predicts relapse risk in pediatric B-cell precursor acute lymphoblastic leukemia in trial AIEOP-BFM-ALL 2000

scientific article published on 18 December 2018

Fluorescence in situ hybridization improves cytogenetic results in the analysis of hepatoblastoma

scientific article published on 01 April 2002

Fluorescent in situ hybridization (FISH) reveals frequent and recurrent numerical and structural abnormalities in hepatoblastoma with no informative karyotype

scientific article published on 01 November 2002

Focal nodular hyperplasia of the liver: an emerging complication of hematopoietic SCT in children

scientific article published on 12 January 2015

Frequency and prognostic implications of JAK 1-3 aberrations in Down syndrome acute lymphoblastic and myeloid leukemia

scientific article published on 03 May 2011

Frequent and sex-biased deletion of SLX4IP by illegitimate V(D)J-mediated recombination in childhood acute lymphoblastic leukemia

scientific article published on 17 September 2013

Frequent cases of RAS-mutated Down syndrome acute lymphoblastic leukaemia lack JAK2 mutations.

scientific article

Functional analysis of missense mutations of OAT, causing gyrate atrophy of choroid and retina

scientific article

Functional characterization of human COQ4, a gene required for Coenzyme Q10 biosynthesis.

scientific article

Functional complementation in yeast allows molecular characterization of missense argininosuccinate lyase mutations

scientific article published on 24 August 2009

Functional protein network activation mapping reveals new potential molecular drug targets for poor prognosis pediatric BCP-ALL

scientific article

GIMEMA-AIEOP AIDA Protocols for the Treatment of Newly Diagnosed Acute Promyelocytic Leukemia (APL) In Children: Analysis of 247 Patients Enrolled In Two Sequential Italian Multicenter Trials ⬇️

scholarly article

GIMEMA-AIEOPAIDA protocol for the treatment of newly diagnosed acute promyelocytic leukemia (APL) in children

scientific article

Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias ⬇️

scientific article

Gain-of-function mutations ininterleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

scientific article published on 21 December 2008

Gene Expression–Based Classification As an Independent Predictor of Clinical Outcome in Juvenile Myelomonocytic Leukemia

scientific article published on 15 March 2010

Gene expression profile unravels significant differences between childhood and adult Ph+ acute lymphoblastic leukemia.

scientific article published in November 2003

Gene expression signatures of pediatric myelodysplastic syndromes are associated with risk of evolution into acute myeloid leukemia.

scientific article published on 7 February 2012

Gene symbol: ASL. Disease: Argininosuccinate lyase deficiency

scientific article

Gene symbol: ASL. Disease: Argininosuccinate lyase deficiency

scientific article published on 01 October 2008

Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia

scientific article published on 25 June 2018

Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia

scientific article published on 24 February 2004

Genetic loss of SH2B3 in acute lymphoblastic leukemia

scientific article published on August 2013

Genetic profile of T-cell acute lymphoblastic leukemias with MYC translocations

scientific article published on 30 September 2014

Genetic risk factors for VIPN in childhood acute lymphoblastic leukemia patients identified using whole-exome sequencing

scientific article published on 07 September 2018

Genomic Landscape of Pediatric Mixed Phenotype Acute Leukemia ⬇️

scholarly article

Genomic and Transcriptomic Analyses Revealed Differences and Similarities Between T-Lbl and T-ALL . ⬇️

scholarly article

Genomic complexity and dynamics of clonal evolution in childhood acute myeloid leukemia studied with whole-exome sequencing

scientific article published on 22 July 2016

Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles ⬇️

scientific article published on June 7, 2011

Genomic subtyping and therapeutic targeting of acute erythroleukemia

scientific article published on 29 March 2019

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options

scientific article

Genotypes of the glutathione S-transferase superfamily do not correlate with outcome of childhood acute lymphoblastic leukemia ⬇️

scientific article published on May 1, 2003

Glioblastoma cancer stem cells: role of the microenvironment and therapeutic targeting

scientific article published on 11 October 2012

Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia.

scientific article published on 3 November 2017

Glutathione S-transferase homozygous deletions and relapse in childhood acute lymphoblastic leukemia: a novel study design in a large Italian AIEOP cohort

scientific article published in December 2012

Good steroid response in vivo predicts a favorable outcome in children with T-cell acute lymphoblastic leukemia. The Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP)

scientific article published on 01 April 1995

HIF-1α/Wnt signaling-dependent control of gene transcription regulates neuronal differentiation of glioblastoma stem cells

scientific article published on 09 July 2019

HSP70/HSF1 axis, regulated via a PI3K/AKT pathway, is a druggable target in chronic lymphocytic leukemia

scientific article published on 15 May 2019

Haemocytes and blastogenetic cycle in the colonial ascidian Botryllus schlosseri: a matter of life and death

scientific article published on 31 October 2007

Haploidentical TCR A/B and B-cell depleted hematopoietic SCT in pediatric SAA and aspergillosis

scientific article published on 07 April 2014

Haploidentical stem cell transplantation cures autoimmune hepatitis and cerebrovascular disease in a patient with sickle cell disease

scientific article published on 15 January 2018

Health-related quality of life in AYA cancer survivors who underwent HSCT compared with healthy peers

scientific article published on 31 July 2018

Hematopoietic Cell Transplantation for Children with High Risk Acute Lymphoblastic Leukemia in First Complete Remission: A Report From the Italian Association of Pediatric Hematology and Oncology (AIEOP) Registry

Hematopoietic stem cell transplantation for children with high-risk acute lymphoblastic leukemia in first complete remission: a report from the AIEOP registry

scientific article published on 26 February 2013

Hematopoietic stem cell transplantation for isolated extramedullary relapse of acute lymphoblastic leukemia in children

scientific article published on 13 June 2018

Hemiasterlin analogues incorporating an aromatic, and heterocyclic type C-terminus: design, synthesis and biological evaluation

scientific article

Hepatic Stem-like Phenotype and Interplay of Wnt/β-Catenin and Myc Signaling in Aggressive Childhood Liver Cancer

Hepatoblastoma: DNA nuclear content, proliferative indices, and pathology ⬇️

scientific article published on April 1, 1998

Hepatocyte growth factor receptor c-MET is associated with FAS and when activated enhances drug-induced apoptosis in pediatric B acute lymphoblastic leukemia with TEL-AML1 translocation

scientific article published on 2 August 2007

Hh/Gli antagonist in acute myeloid leukemia with CBFA2T3-GLIS2 fusion gene

scientific article published on 21 January 2017

High Clonal Evolution Rate in Relapsing Infant ALL Patients. ⬇️

scholarly article

High Risk Acute Lymphoblastic Leukemia with Rapid NOD/SCID Engraftment Is Characterized by High Protein Expression of CYCLIN B, Beta-CATENIN, ANNEXIN I and Decreased PKC Alpha Activation ⬇️

scholarly article

High expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia.

scientific article published on 21 March 2017

Hovering between death and life: Natural apoptosis and phagocytes in the blastogenetic cycle of the colonial ascidian Botryllus schlosseri

scientific article published on 28 October 2009

Hybrid alpha-bromoacryloylamido chalcones. Design, synthesis and biological evaluation

scientific article published on 12 February 2009

Hypoxia and HIF1alpha repress the differentiative effects of BMPs in high-grade glioma

scientific article published in January 2009

Hypoxia and succinate antagonize 2-deoxyglucose effects on glioblastoma

scientific article published on 10 August 2010

ICER evokes Dusp1-p38 pathway enhancing chemotherapy sensitivity in myeloid leukemia.

scientific article published in February 2011

ICER expression inhibits leukemia phenotype and controls tumor progression

scientific article published on 11 September 2008

IKZF1 and 22q11.22 Deletions and PDGFRA Gains Are Associated with Poor Outcome in Down Syndrome Acute Lymphoblastic Leukemia ⬇️

scholarly article

IKZF1plus Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

scientific article published on 2 March 2018

Identification Of Low Risk Group In Infants With Acute Lymphoblastic Leukemia By Flow Cytometric Minimal Residual Disease Measurement At Day 15 Of Interfant-99 and Interfant-06 Protocols Treatment ⬇️

scholarly article

Identification of New Genomic Lesions in Childhood ALL without Known Genetic Aberrations: A Microarray Study of Gene Expression and Genotype Data. ⬇️

scholarly article

Identification of immunophenotypic signatures by clustering analysis in pediatric patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

scientific article published on 01 February 2010

Identification of somatic and germline mutations using whole exome sequencing of congenital acute lymphoblastic leukemia

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Identification of the NUP98-PHF23 fusion gene in pediatric cytogenetically normal acute myeloid leukemia by whole-transcriptome sequencing

scientific article published on 12 June 2015

Imatinib mesylate (STI571) interference with growth of neuroectodermal tumour cell lines does not critically involve c-Kit inhibition

scientific article published on September 2004

Immunobiological diversity in infant acute lymphoblastic leukemia is related to the occurrence and type of MLL gene rearrangement.

scientific article published in February 2007

Immunogenotype changes prevail in relapses of young children with TEL-AML1-positive acute lymphoblastic leukemia and derive mainly from clonal selection

scientific article published on 01 November 2005

Immunohistochemical Distribution of Endothelin in Biopsies of Pediatric Nephrotic Syndrome

scientific article published on 01 January 1994

Immunophenotype of adult and childhood acute promyelocytic leukaemia: correlation with morphology, type of PML gene breakpoint and clinical outcome. A cooperative Italian study on 196 cases

scientific article published on 01 September 1998

Immunophenotype signature as a tool to define prognostic subgroups in childhood acute myeloid leukemia

scientific article published on 01 May 2006

Impact of IKZF1 deletions on IKZF1 expression and outcome in Philadelphia chromosome negative childhood BCP-ALL. Reply to "incidence and biological significance of IKZF1/Ikaros gene deletions in pediatric Philadelphia chromosome negative and Philade

scientific article published on December 2013

Improved outcome in high-risk childhood acute lymphoblastic leukemia defined by prednisone-poor response treated with double Berlin-Frankfurt-Muenster protocol II.

scientific article published in July 2002

Improvement and extension of anti-EGFR targeting in breast cancer therapy by integration with the Avidin-Nucleic-Acid-Nano-Assemblies

scientific article published in Nature Communications

In Infant ALL with t(4;11)/MLL-AF4 Multiple and Phenotypically Distinct CD19+ BM Subsets Initiate Leukemia in NOD/SCID Mice..

scientific article published in 2009

Incidence and prognostic significance of immunophenotypic subgroups in childhood acute lymphoblastic leukemia: the experience of the AIEOP Cooperative Study. Associazione Italiana Ematologia Oncologia Pediatrica

scientific article published on 01 January 1993

Increased levels of a chromosome 21-encoded tumour invasion and metastasis factor (TIAM1) mRNA in bone marrow of Down syndrome children during the acute phase of AML(M7)

scientific article published on 01 September 1998

Increased levels of a chromosome 21-encoded tumour invasion and metastasis factor(TIAM1) mRNA in bone marrow of down syndrome children during the acute phase of AML(M7)

article by Jane H. Ives et al published September 1998 in Genes, Chromosomes and Cancer

Independent clones at separable stages of differentiation, bearing different GATA1 mutations, in the same TMD patient with Down syndrome.

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Individual and combined effect of granulocyte-macrophage colony-stimulating factor and prolactin on maturation of dendritic cells from blood monocytes under serum-free conditions

scientific article published on 01 May 2000

Induction of Expandable Tissue-Specific Stem/Progenitor Cells through Transient Expression of YAP/TAZ.

scientific article published on 09 September 2016

Induction of apoptosis by photoexcited tetracyclic compounds derivatives of benzo[b]thiophenes and pyridines

scientific article published on 2 November 2005

Induction of apoptosis in Jurkat cells by photoexcited psoralen derivatives: Implication of mitochondrial dysfunctions and caspases activation.

scientific article published on 30 September 2006

Induction of gamma-globin mRNA, erythroid differentiation and apoptosis in UVA-irradiated human erythroid cells in the presence of furocumarin derivatives.

scientific article published on 13 October 2007

Infantile encephalomyopathy and nephropathy with CoQ10 deficiency: a CoQ10-responsive condition.

scientific article published in August 2005

Infants with acute myeloid leukemia treated according to the Associazione Italiana di Ematologia e Oncologia Pediatrica 2002/01 protocol have an outcome comparable to that of older children

scientific article published on 16 May 2014

Inhibition of PI3K Signalling Selectively Affects Medulloblastoma Cancer Stem Cells

scientific article published on 18 October 2015

Integration of genomic and gene expression data of childhood ALL without known aberrations identifies subgroups with specific genetic hallmarks

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Integrin expression and IgA nephropathy: in vitro modulation by IgA with altered glycosylation and macromolecular IgA

scientific article published on 01 December 2000

Intellectual function evaluation of first generation immigrant children with sickle cell disease: the role of language and sociodemographic factors

scientific article published on 04 June 2013

Interaction of hypoxia-inducible factor-1α and Notch signaling regulates medulloblastoma precursor proliferation and fate.

scientific article

Interleukin-22 in the diagnosis of active chronic graft-versus-host disease in paediatric patients

scientific article published on 7 August 2014

Interleukin-23 acts as antitumor agent on childhood B-acute lymphoblastic leukemia cells ⬇️

scientific article published on July 29, 2010

Interleukin-27 inhibits pediatric B-acute lymphoblastic leukemia cell spreading in a preclinical model ⬇️

scientific article published on June 24, 2011

International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia.

scientific article published on 2 May 2018

Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma.

scientific article published in May 2010

Intron 2 [IVS2, T-C +4] HFE gene mutation associated with S65C causes alternative RNA splicing and is responsible for iron overload

scientific article published on 11 August 2005

Is the deletion of the short arm of chromosome 1 a prognostic factor in pediatric peripheral primitive neuroepithelioma (PNET)?

scientific article published on 01 February 1996

Isoindolo[2,1-a]quinoxaline derivatives, novel potent antitumor agents with dual inhibition of tubulin polymerization and topoisomerase I.

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Isolation and expansion of regionally defined human glioblastoma cells in vitro

scientific article published in May 2011

JAK/STAT/PKCδ molecular pathways in synovial fluid T lymphocytes reflect the in vivo T helper-17 expansion in psoriatic arthritis

scientific article published on 01 January 2014

Karyotype evolution in a patient with biphenotypic neonatal leukemia

scientific article published on September 1992

Kinetics of Circulating Plasma Cell-Free DNA in Paediatric Classical Hodgkin Lymphoma

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L-Proline as a modulator of ectodermal differentiation in ES cells. Focus on "L-Proline induces differentiation of ES cells: a novel role for an amino acid in the regulation of pluripotent cells in culture.

scientific article published on 10 March 2010

LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients

scientific article

LIN28B increases neural crest cell migration and leads to transformation of trunk sympathoadrenal precursors

scientific article published on 10 October 2019

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia.

scientific article published on 28 December 2015

Lack of Protein Kinase C Alpha Is Associated with Poor Prognosis in Pediatric T-Lineage Acute Lymphoblastic Leukemia ⬇️

scholarly article

Large and dissimilar repertoire of Melan-A/MART-1-specific CTL in metastatic lesions and blood of a melanoma patient

Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.

scientific article

Late mortality and causes of death among 5-year survivors of childhood cancer diagnosed in the period 1960-1999 and registered in the Italian Off-Therapy Registry

scientific article published on 14 February 2019

Late recurrence of childhood T-cell acute lymphoblastic leukemia frequently represents a second leukemia rather than a relapse: first evidence for genetic predisposition.

scientific article published on 28 February 2011

Late relapse of childhood acute lymphoblastic leukemia and pcr-monitoring of minimal residual disease: how much time can elapse between "molecular" and clinical relapse?

scientific article published on 01 April 2002

Latent hepatitis B virus infection in childhood hepatocellular carcinoma. Analysis by polymerase chain reaction.

scientific article published on June 1992

Linking genomic lesions with minimal residual disease improves prognostic stratification in children with T-cell acute lymphoblastic leukaemia.

scientific article published on 2 June 2013

LncRNA Expression Discriminates Karyotype and Predicts Survival in B-Lymphoblastic Leukemia

scientific article published on 13 February 2015

Long-Term Outcome of Children with Acute Myeloid Leukemia in First Remission Given Allogeneic HSCT from a Matched Family Donor After a Conditioning Regimen Comprising Busulfan, Cyclophosphamide and Melphalan. ⬇️

scholarly article

Long-Term Outcome of Relapsed Acute T-Lymphoblastic Leukemia (T-ALL) in Children and Adolescents ⬇️

scholarly article

Long-term results of AIEOP-8805 protocol for acute B-cell lymphoblastic leukemia of childhood

scientific article published on 15 December 2010

Long-term results of a randomized trial on extended use of high dose L-asparaginase for standard risk childhood acute lymphoblastic leukemia

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Long-term results of the AIEOP LNH-97 protocol for childhood lymphoblastic lymphoma

scientific article published on 8 March 2015

Long-term results of the AIEOP-ALL-95 Trial for Childhood Acute Lymphoblastic Leukemia: insight on the prognostic value of DNA index in the framework of Berlin-Frankfurt-Muenster based chemotherapy

scientific article published in January 2008

Long-term results of the Italian Association of Pediatric Hematology and Oncology (AIEOP) acute lymphoblastic leukemia studies, 1982-1995.

scientific article published in December 2000

Longitudinal evaluation of cerebral white matter hyperintensities lesion volume in children with sickle cell disease

scientific article published on 27 March 2016

Loss of PTEN in Pediatric T-Cell Acute Lymphoblastic Leukemia Patients: Proteomic and Molecular Characterization ⬇️

scholarly article

Loss-of-function JAK3 mutations in TMD and AMKL of Down syndrome

scientific article published on 01 May 2007

Low PKCα expression within the MRD-HR stratum defines a new subgroup of childhood T-ALL with very poor outcome

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Lymphocytes subsets reference values in childhood

scientific article published on 6 August 2014

MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells

scientific article published on 22 September 2011

MGMT expression and promoter methylation status may depend on the site of surgical sample collection within glioblastoma: a possible pitfall in stratification of patients?

scientific article

MLL partner genes drive distinct gene expression profiles and genomic alterations in pediatric acute myeloid leukemia: an AIEOP study

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MLL rearrangements in pediatric acute lymphoblastic and myeloblastic leukemias: MLL specific and lineage specific signatures

scientific article published on 23 June 2009

MLL-AF6 fusion oncogene sequesters AF6 into the nucleus to trigger RAS activation in myeloid leukemia

scientific article published on 2 April 2014

MYCN oncogene amplification in neuroblastoma is associated with worse prognosis, except in stage 4s: the Italian experience with 295 children

scientific article published on 01 January 1997

Macrolide Antibiotics By Modulating the Autophagic Flux Exert an Antileukemic Effect through the Involvement of hERG1 Potassium Channel ⬇️

scholarly article

Methylation of the IL-12Rbeta2 gene as novel tumor escape mechanism for pediatric B-acute lymphoblastic leukemia cells

scientific article published on April 2006

MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma

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MiR-34b Promoter Methylation and Regulation of CREB Expression In Myeloid Transformation ⬇️

scholarly article

MicroRNA fingerprints in juvenile myelomonocytic leukemia (JMML) identified miR-150-5p as a tumor suppressor and potential target for treatment

scientific article published on 13 July 2016

MicroRNA-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation

scientific article published on 25 October 2012

Microarray transcript profiling distinguishes the transient from the acute type of megakaryoblastic leukaemia (M7) in Down's syndrome, revealing PRAME as a specific discriminating marker.

scientific article published in June 2004

Microrna-150 Regulates STAT5b Levels in Juvenile Myelomonocytic Leukemia (JMML) ⬇️

scholarly article

Minimal Residual Disease Monitoring In Acute Lymphoblastic Leukemia Patients Using Immune Receptor Sequencing ⬇️

scholarly article

Minimal residual disease analysis by eight-color flow cytometry in relapsed childhood acute lymphoblastic leukemia.

scientific article

Minimal residual disease monitored after induction therapy by RQ-PCR can contribute to tailor treatment of patients with t(8;21) RUNX1-RUNX1T1 rearrangement

scientific article published on 5 December 2014

Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leu

scientific article published on 31 January 2008

Modulation of antigen expression in B-cell precursor acute lymphoblastic leukemia during induction therapy is partly transient: evidence for a drug-induced regulatory phenomenon. Results of the AIEOP-BFM-ALL-FLOW-MRD-Study Group

scientific article published on 01 May 2010

Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150.

scientific article

Molecular Characterization of Long Non-Coding RNA CASC15 in Leukemogenesis ⬇️

scholarly article

Molecular characterization of Ph' + hybrid acute leukemia

scientific article published on 01 January 1989

Molecular characterization of a new recombination of the SIL/TAL-1 locus in a child with T-cell acute lymphoblastic leukaemia

scientific article (publication date: September 2002)

Molecular mechanisms of HIF-1alpha modulation induced by oxygen tension and BMP2 in glioblastoma derived cells

scientific article

Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study

scientific article published on 12 February 2010

Mosaic Distribution of RAS Pathway Mutated and Non Mutated Cells in Bone Marrow of Juvenile Myelomonocytic Leukemia. ⬇️

scholarly article

Motor skill delays in pre-school children with leukemia one year after treatment: Hematopoietic stem cell transplantation therapy as an important risk factor.

scientific article

Mutational Loss of PTEN Induces Resistance to NOTCH1 Inhibition in T-ALL. ⬇️

scholarly article

Mutational and functional genetics mapping of chemotherapy resistance mechanisms in relapsed acute lymphoblastic leukemia

scientific article published on 19 October 2020

Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia

scientific article published on 21 September 2016

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

scientific article published on 16 September 2007

Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

scientific article published on 19 September 2008

Mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia: a report from the Italian AIEOP study group

scientific article published on 9 March 2016

N-acetyl-beta-D-glucosaminidase activity in T chronic lymphocytic leukaemia

scientific article published on 01 January 1981

N-myc and c-myc oncogenes amplification in medulloblastomas. Evidence of particularly aggressive behavior of a tumor with c-myc amplification.

scientific article published in April 1991

NOVEL Recurrent Genetic Aberrations in Pediatric AML: An AIEOP AML-2002 Study Group. ⬇️

scholarly article

NUP98 Fusion Proteins Are Recurrent Aberrancies in Childhood Acute Myeloid Leukemia: A Report from the AIEOP AML-2001-02 Study Group ⬇️

scholarly article

Natural daucane esters induces apoptosis in leukaemic cells through ROS production

scientific article published on 4 October 2014

Natural daucane sesquiterpenes with antiproliferative and proapoptotic activity against human tumor cells.

scientific article

Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction

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New data on robustness of gene expression signatures in leukemia: comparison of three distinct total RNA preparation procedures

scientific article

New more polar symmetrical bipyridinic compounds: new strategy for the inhibition of choline kinase α1.

scientific article published on January 2015

New pyrimido-indole compound CD-160130 preferentially inhibits the KV11.1B isoform and produces antileukemic effects without cardiotoxicity

scientific article

Next-generation sequencing of PTEN mutations for monitoring minimal residual disease in T-cell acute lymphoblastic leukemia

scientific article published on 01 October 2019

Non-Hodgkin lymphoma in children with an associated inherited condition: A retrospective analysis of the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP).

scientific article published on 22 May 2015

Non-T, non-B childhood acute lymphoblastic leukemia. Correlation between cytochemical markers and first complete remission

scientific article published on 01 September 1984

Non-radiolabelled PCR consensus primers and automatic sequencing enable rapid identification of tumor-specific V(H) CDR3 in aggressive B-cell malignancies.

scientific article

Notch3-mediated regulation of MKP-1 levels promotes survival of T acute lymphoblastic leukemia cells

scientific article published on 25 January 2011

Novel 3-Substituted 7-Phenylpyrrolo[3,2-f]quinolin-9(6H)-ones as Single Entities with Multitarget Antiproliferative Activity

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Novel 9'-substituted-noscapines: synthesis with Suzuki cross-coupling, structure elucidation and biological evaluation

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Nucleophosmin mutations in childhood acute myelogenous leukemia with normal karyotype

scientific article published on 03 May 2005

One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazole: a unique, highly active antimicrotubule agent

scientific article published on 15 October 2011

Optimization of PCR-based minimal residual disease diagnostics for childhood acute lymphoblastic leukemia in a multi-center setting.

scientific article published on 8 February 2007

Osteonecrosis: An emerging complication of intensive chemotherapy for childhood acute lymphoblastic leukemia

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Outcome after cessation of therapy in childhood acute lymphoblastic leukaemia. The Associazione Italiana Ematologia ed Oncologia Pediatrica (AIEOP)

scientific article published on 01 January 1993

Outcome of Children With Hypodiploid Acute Lymphoblastic Leukemia: A Retrospective Multinational Study

scientific article published on 18 January 2019

Outcome of children with acute myeloid leukaemia (AML) experiencing primary induction failure in the AIEOP AML 2002/01 clinical trial

scientific article published on 30 July 2015

Outcome of treatment in children with hypodiploid acute lymphoblastic leukemia

scientific article published in May 2007

Outcomes of Children with Hemophagocytic Lymphohistiocytosis Given Allogeneic Hematopoietic Stem Cell Transplantation in Italy.

scientific article published in February 2018

Overcoming Chemotherapy Resistance in Childhood Acute Lymphoblastic Leukemia by Targeting Ion Channels. ⬇️

scholarly article

Oxygen tension controls the expansion of human CNS precursors and the generation of astrocytes and oligodendrocytes

scientific article

PDAC-derived exosomes enrich the microenvironment in MDSCs in a SMAD4-dependent manner through a new calcium related axis.

scientific article published on 13 September 2017

PTPN11 mutations in childhood acute lymphoblastic leukemia occur as a secondary event associated with high hyperdiploidy.

scientific article published on 24 September 2009

Pancreatic tumors and immature immunosuppressive myeloid cells in blood and spleen: role of inhibitory co-stimulatory molecules PDL1 and CTLA4. An in vivo and in vitro study

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Peculiar allelotype associated with susceptibility to neuroblastoma

scientific article published in September 1996

Perceived social support and health-related quality of life in AYA cancer survivors and controls

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Persistence of E2A/PBX1 transcripts in t(1;19) childhood acute lymphoblastic leukemia: correlation with chemotherapy intensity and clinical outcome.

scientific article published in May 1996

Pharmacological Inhibition of Lck is Able to Revert Glucocorticoid Resistance in Pediatric T-ALL ⬇️

scholarly article

Phenotypic and functional characterization of Glioblastoma cancer stem cells identified through 5-aminolevulinic acid-assisted surgery [corrected].

scientific article

Phf6 Loss Enhances HSC Self-Renewal Driving Tumor Initiation and Leukemia Stem Cell Activity in T-ALL

scientific article published on 19 December 2018

Philadelphia-Like Signature In Childhood Acute Lymphoblastic Leukemia: The AIEOP Experience ⬇️

scholarly article

Photophysical properties and photobiological behavior of amodiaquine, primaquine and chloroquine

scientific article

Pitavastatin, a new HMG-CoA reductase inhibitor, induces phototoxicity in human keratinocytes NCTC-2544 through the formation of benzophenanthridine-like photoproducts.

scientific article

Poor prognosis for P2RY8-CRLF2 fusion but not for CRLF2 over-expression in children with intermediate risk B-cell precursor acute lymphoblastic leukemia

scientific article published on 09 April 2012

Post-traumatic Stress Symptoms and Post-traumatic Growth in 223 Childhood Cancer Survivors: Predictive Risk Factors

scientific article published on 29 February 2016

Postinduction minimal residual disease monitoring by polymerase chain reaction in children with acute lymphoblastic leukemia

scientific article published on 6 October 2014

Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia

scientific article published on 22 May 2020

Pre- and post-transplant minimal residual disease predicts relapse occurrence in children with acute lymphoblastic leukaemia

scientific article

Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma

scientific article published on 03 August 2018

Prednisone induces immunophenotypic modulation of CD10 and CD34 in nonapoptotic B-cell precursor acute lymphoblastic leukemia cells.

scientific article

Presence of high-ERG expression is an independent unfavorable prognostic marker in MLL-rearranged childhood myeloid leukemia

scientific article published on 01 January 2012

Prevalence and Prognostic Impact of CEBPA mutations in Children with AML Treated with the AIEOP-LAM 2002/01 Protocol. ⬇️

scholarly article

Prevalence and clinical correlates of JAK2 mutations in Down syndrome acute lymphoblastic leukaemia.

scientific article published on 20 December 2008

Proapoptotic effect of hepatitis C virus CORE protein in transiently transfected cells is enhanced by nuclear localization and is dependent on PKR activation.

scientific article published in January 2004

Profiling B cell chronic lymphocytic leukemia by reverse phase protein array: Focus on apoptotic proteins

scientific article published on 16 June 2016

Prognostic Role of Minimal Residual Disease before and after Hematopoietic Stem Cell Transplantation in Childhood Acute Lymphoblastic Leukemia ⬇️

scholarly article

Prognostic Value of Immunophenotype In Infant ALL – Results of the INTERFANT'99 Study ⬇️

scholarly article

Prognostic role of minimal residual disease in mature B-cell acute lymphoblastic leukemia of childhood.

scientific article published in November 2007

Prognostic significance of flow-cytometry evaluation of minimal residual disease in children with acute myeloid leukaemia treated according to the AIEOP-AML 2002/01 study protocol.

scientific article published on 27 February 2017

Prognostic significance of minimal residual disease in infants with acute lymphoblastic leukemia treated within the Interfant-99 protocol.

scientific article published on 12 February 2009

Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood.

scientific article

Prognostic value of minimal residual disease measured by flow-cytometry in two cohorts of infants with acute lymphoblastic leukemia treated according to either MLL-Baby or Interfant protocols

scientific article published on 12 June 2020

Prognostic value of rhodamine-efflux and MDR-1/P-170 expression in childhood acute leukemia.

scientific article

Prospective molecular monitoring of BCR/ABL transcript in children with Ph+ acute lymphoblastic leukaemia unravels differences in treatment response

scientific article published in November 2002

Proteomic Alterations in Response to Hypoxia Inducible Factor 2α in Normoxic Neuroblastoma Cells

scientific article published on 5 September 2016

Protocol II vs protocol III given twice during reinduction therapy in children with medium-risk ALL.

scientific article published on 22 September 2017

Psychopathological Aspects in Childhood Hematopoietic Stem Cell Transplantation (HSCT): The Perception of Parents and Adolescents

scientific article published on 05 April 2017

Psychosocial life achievements in adults even if they received prophylactic cranial irradiation for acute lymphoblastic leukemia during childhood.

scientific article published on 8 September 2012

Pyrrolo[3,4-h]quinolinones a new class of photochemotherapeutic agents

scientific article published on 18 February 2011

Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition

scientific article published on 11 April 2009

Quality of Life and Psychopathology in Adults Who Underwent Hematopoietic Stem Cell Transplantation (HSCT) in Childhood: A Qualitative and Quantitative Analysis.

scientific article published on 8 August 2017

RAS-protein activation but not mutation status is an outcome predictor and unifying therapeutic target for high-risk acute lymphoblastic leukemia

scientific article published on 27 November 2020

RNA-binding protein IGF2BP3 targeting of oncogenic transcripts promotes hematopoietic progenitor proliferation.

scientific article published on 14 March 2016

Randomized post-induction and delayed intensification therapy in high-risk pediatric acute lymphoblastic leukemia: long-term results of the international AIEOP-BFM ALL 2000 trial

scientific article published on 5 December 2019

Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia

scientific article published on 18 October 2009

Recent advances in vascular disrupting agents in cancer therapy.

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Recognition of adult and pediatric acute lymphoblastic leukemia blasts by natural killer cells

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Recommended reporting format for flow cytometry diagnosis of acute leukemia

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Reduced Intensity Delayed Intensification in Standard-Risk Patients Defined By Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia: Results of an International Randomized Trial in 1164 Patients (Trial AIEOP-BFM ALL 2000) ⬇️

scholarly article

Reduced-Intensity Delayed Intensification in Standard-Risk Pediatric Acute Lymphoblastic Leukemia Defined by Undetectable Minimal Residual Disease: Results of an International Randomized Trial (AIEOP-BFM ALL 2000).

scientific article published on 17 November 2017

Relapses and treatment-related events contributed equally to poor prognosis in children with ABL-class fusion positive B-cell acute lymphoblastic leukemia treated according to AIEOP-BFM protocols

scientific article published on 10 October 2019

Restriction fragment length polymorphism analysis reveals different allele frequency and a linkage disequilibrium at locus D1S94 in neuroblastoma patients

scientific article published in October 1997

Results of a multicenter universal newborn screening program for sickle cell disease in Italy: A call to action

scientific article published on 05 February 2019

Results of the AIEOP AML 2002/01 multicenter prospective trial for the treatment of children with acute myeloid leukemia

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Results of the AIEOP-BFM ALL 2000 Study for Childhood Acute Lymphoblastic Leukemia IN AIEOP High Risk Patients. ⬇️

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Reversal of the glycolytic phenotype of primary effusion lymphoma cells by combined targeting of cellular metabolism and PI3K/Akt/ mTOR signaling.

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Rhabdomyosarcoma with primary osteolytic lesions simulating non-Hodgkin's lymphoma

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Ribociclib, A Cdk4/Cdk6 Kinase Inhibitor, Enhances Glucocorticoid Sensitivity In B-Acute Lymphoblastic Leukemia (B-All).

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Risk Factors and Outcomes Related to Pediatric Intensive Care Unit Admission after Hematopoietic Stem Cell Transplantation: A Single-Center Experience

scientific article published on 28 April 2017

Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow.

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Risk-directed therapy for childhood acute lymphoblastic leukemia. Results of the Associazione Italiana Ematologia Oncologia Pediatrica '82 studies

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Role of TAZ as mediator of Wnt signaling

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Role of cranial radiotherapy for childhood T-cell acute lymphoblastic leukemia with high WBC count and good response to prednisone. Associazione Italiana Ematologia Oncologia Pediatrica and the Berlin-Frankfurt-Münster groups

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Role of treatment intensification in infants with acute lymphoblastic leukemia: results of two consecutive AIEOP studies.

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SF3B1 homeostasis is critical for survival and therapeutic response in T cell leukemia

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SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors.

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STAT5 Phosphorylation Status by Flow Cytometry Is a Rapid and Reliable Tool for Diagnosis and Follow-up of Juvenile Myelomonocytic Leukemia ⬇️

scholarly article

SYK Targeting Represents a Potential Therapeutic Option for Relapsed Resistant Pediatric ETV6-RUNX1 B-Acute Lymphoblastic Leukemia Patients ⬇️

scientific article published on 07 December 2019

Screening of novel genetic aberrations in pediatric acute myeloid leukemia: a report from the AIEOP AML-2002 study group.

scientific article published in November 2012

Secondary cytogenetic aberrations in childhood Philadelphia chromosome positive acute lymphoblastic leukemia are nonrandom and may be associated with outcome

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Selective Difficulties in Lexical Retrieval and Nonverbal Executive Functioning in Children With HbSS Sickle Cell Disease

scientific article published on 8 February 2018

Selective killing of human T-ALL cells: an integrated approach targeting redox homeostasis and the OMA1/OPA1 axis

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Self-Esteem and Academic Difficulties in Preadolescents and Adolescents Healed from Paediatric Leukaemia

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Serum miRNA Are Promising Biomarkers for the Detection of Early Hepatocellular Carcinoma after Treatment with Direct-Acting Antivirals

scientific article published on 11 November 2019

Sex-dependent differences in inflammatory responses during liver regeneration in a murine model of acute liver injury

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Significance of serial biopsies after renal allograft in children

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Somatic PTPN11 mutations in childhood acute myeloid leukaemia

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Somatic mutations activating Wiskott-Aldrich syndrome protein concomitant with RAS pathway mutations in Juvenile myelomonocytic leukemia patients.

scientific article published on 7 January 2018

Standardization of flow cytometric minimal residual disease evaluation in acute lymphoblastic leukemia: Multicentric assessment is feasible.

scientific article published in November 2008

Study of cytochemical markers ACP and ANAE in childhood lymphoma and leukaemia.

scientific article published on May 1980

Subunit a of Coagulation Factor XIII As a New Biomarker in Childhood Acute Lymphoblastic Leukemia? ⬇️

scholarly article

Symmetrical alpha-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluation.

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Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents

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Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues

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Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-aryl/arylaminobenzo[b]thiophene derivatives as a novel class of antiproliferative agents.

scientific article

Synthesis and biological evaluation of 2-(alkoxycarbonyl)-3-anilinobenzo[b]thiophenes and thieno[2,3-b]pyridines as new potent anticancer agents

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Synthesis and biological evaluation of 2-substituted-4-(3',4',5'-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents

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Synthesis and biological evaluation of imidazo[1,2-a]pyrimidines and imidazo[1,2-a]pyridines as new inhibitors of the Wnt/β-catenin signaling.

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Synthesis and biological evaluation of new geiparvarin derivatives

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Synthesis and evaluation of 1,5-disubstituted tetrazoles as rigid analogues of combretastatin A-4 with potent antiproliferative and antitumor activity

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Synthesis and in vitro evaluation of 3h-pyrrolo[3,2-f]-quinolin-9-one derivatives that show potent and selective anti-leukemic activity

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Synthesis and photochemotherapeutic activity of thiopyrano[2,3-e]indol-2-ones

scientific article

Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles

scientific article

Synthesis, cytotoxicity, and apoptosis induction in human tumor cells by geiparvarin analogues

scientific article

Synthesis, structure-activity relationships and biological evaluation of 7-phenyl-pyrroloquinolinone 3-amide derivatives as potent antimitotic agents.

scientific article

T cells stimulated by CD40L positive leukemic blasts-pulsed dendritic cells meet optimal functional requirements for adoptive T-cell therapy.

scientific article published on 21 September 2006

T-cell lymphoblastic lymphoma shows differences and similarities with T-cell acute lymphoblastic leukemia by genomic and gene expression analyses

scientific article published on 30 August 2011

TEL/AML1 Rearrangement Is Rare in Children with Acute Lymphoblastic Leukemia (ALL) and Down Syndrome (DS). Presenting Features and Treatment Outcome in the Experience of the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP). ⬇️

scholarly article

TNF-α SNP rs1800629 and risk of relapse in childhood acute lymphoblastic leukemia: relation to immunophenotype.

scientific article published in April 2014

TP-0903 inhibits neuroblastoma cell growth and enhances the sensitivity to conventional chemotherapy.

scientific article published on 14 November 2017

TR-644 a novel potent tubulin binding agent induces impairment of endothelial cells function and inhibits angiogenesis

scientific article published on 2 March 2013

Targeting BAG-1: a novel strategy to increase drug efficacy in acute myeloid leukemia

scientific article published on 11 November 2014

Targeting Glioblastoma with the Use of Phytocompounds and Nanoparticles

scientific article published on 16 August 2015

The COQ2 genotype predicts the severity of coenzyme Q10 deficiency

scientific journal article

The Clinical Utility of Microarray-Based Gene Expression Profiling in the Diagnosis and Sub-Classification of Leukemia: Final Report on 3252 Cases from the International MILE Study Group ⬇️

scholarly article

The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells

scientific article

The Human AF9 Homologue in Zebrafish Is Involved in Primitive Hematopoietic Development. ⬇️

scholarly article

The MIF-173G/C polymorphism does not contribute to prednisone poor response in vivo in childhood acute lymphoblastic leukemia.

scientific article

The Novel Antitubulin Agent TR-764 Strongly Reduces Tumor Vasculature and Inhibits HIF-1α Activation.

scientific article

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

scientific article

The altered transcriptome of pediatric myelodysplastic syndrome revealed by RNA sequencing

scientific article published on 12 October 2020

The c-kit receptor and its ligand stem cell factor in childhood malignant lymphoid precursors.

scientific article

The cAMP Response Element Binding Protein (CREB) Overexpression Induces Myeloid Transformation in Zebrafish ⬇️

scholarly article

The effect of cytokines, including IL4, IL7, stem cell factor, insulin-like growth factor on childhood acute lymphoblastic leukemia

scientific article published on 01 August 1997

The effect of the cyclin-dependent kinase inhibitor flavopiridol on anaplastic large cell lymphoma cells and relationship with NPM-ALK kinase expression and activity

scientific article published on 16 June 2009

The effects of siRNA-mediated inhibition of E2A-PBX1 on EB-1 and Wnt16b expression in the 697 pre-B leukemia cell line.

scientific article

The genetic basis and cell of origin of mixed phenotype acute leukaemia

scientific article published in Nature

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

scientific article

The guanine triphosphatase (GTPase) activating protein (GAP)-related domain of the neurofibromatosis type 1 gene is not mutated in neural crest-derived sporadic tumours

scientific article published on 01 March 1998

The hematopoietic stem cell marker VNN2 is associated with chemoresistance in pediatric B-cell precursor ALL

scientific article published on 01 September 2020

The lncRNA CASC15 regulates SOX4 expression in RUNX1-rearranged acute leukemia.

scientific article

The micro-RNA 199b-5p regulatory circuit involves Hes1, CD15, and epigenetic modifications in medulloblastoma.

scientific article published on 12 March 2012

The phototoxicity of fluvastatin, an HMG-CoA reductase inhibitor, is mediated by the formation of a benzocarbazole-like photoproduct.

scientific article published on 28 July 2010

The presence of mutated and deleted PTEN is associated with an increased risk of relapse in childhood T cell acute lymphoblastic leukaemia treated with AIEOP-BFM ALL protocols

scientific article published on 25 June 2018

The role of immunophenotype in acute lymphoblastic leukemia of infant age.

scientific article published on September 1994

The side population of ovarian cancer cells is a primary target of IFN-alpha antitumor effects.

scientific article

The three-layer concentric model of glioblastoma: cancer stem cells, microenvironmental regulation, and therapeutic implications

scientific article

Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts.

scientific article published on 18 June 2013

Therapeutic effectiveness of recombinant cancer vaccines is associated with a prevalent T-cell receptor alpha usage by melanoma-specific CD8+ T lymphocytes.

scientific article published in November 2004

Therapy-resistant acute lymphoblastic leukemia (ALL) cells inactivate FOXO3 to escape apoptosis induction by TRAIL and Noxa

scientific article published on July 2013

Three Dimensional Speckle Tracking Echocardiography (3D-STE) for Early Detection of Subtle Myocardial Deformation Dysfunction in Thalassemic Patients ⬇️

scholarly article

Three novel fusion transcripts of the paired box 5 gene in B-cell precursor acute lymphoblastic leukemia

scientific article published on 10 October 2014

Three-Drug Induction and BFM-Type Intensive Consolidation Chemotherapy for Treatment of Standard Risk Childhood Acute Lymphoblastic Leukemia Defined Also by DNA index. The Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) Study ALL-9501. ⬇️

scholarly article

Time point-dependent concordance of flow cytometry and real-time quantitative polymerase chain reaction for minimal residual disease detection in childhood acute lymphoblastic leukemia

scientific article

Transcriptional network profile on synovial fluid T cells in psoriatic arthritis

scientific article published on 09 July 2015

Transient acute monoblastic leukemia with reciprocal (8;16)(p11;p13) translocation

scientific article published on 01 March 1996

Treatment and long-term results in children with acute myeloid leukaemia treated according to the AIEOP AML protocols.

scientific article published in December 2005

Treatment of Acute Graft-versus-Host Disease in Childhood with Extracorporeal Photochemotherapy/Photopheresis: The Padova Experience.

scientific article published on 13 July 2015

Treatment reduction in highly selected standard-risk childhood acute lymphoblastic leukemia. The AIEOP ALL-9501 study.

scientific article

Treosulfan-Based Conditioning Regimen in Sibling and Alternative Donor Hematopoietic Stem Cell Transplantation for Children with Sickle Cell Disease

scientific article

Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor.

scientific article

Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells

scientific article

Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis

scientific article published on 19 September 2017

Two consecutive immunophenotypic switches in a child with MLL-rearranged acute lymphoblastic leukemia

scientific article published on 01 May 2006

Two independent gene signatures in pediatric t(4;11) acute lymphoblastic leukemia patients.

scientific article published on 25 June 2009

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia

scientific article published on 17 September 2018

Understanding the Interplay between Expression, Mutation and Activity of ALK Receptor in Rhabdomyosarcoma Cells for Clinical Application of Small-Molecule Inhibitors

scientific article

Validation by RQ-PCR and flow cytometry of alpha-defensin1-3 (DEFA1-3) overexpression in relapsed and refractory acute lymphoblastic leukemia.

scientific article

Validation of MRD Quantification By Flow Cytometry for Pediatric BCP ALL Relapsed Patients Treated on the Intreall Protocol ⬇️

scholarly article

Validation of Minimal Residual Disease as Surrogate Endpoint for Event-Free Survival in Childhood Acute Lymphoblastic Leukemia

scientific article published on 01 October 2018

Validation of NG2 antigen in identifying BP-ALL patients with MLL rearrangements using qualitative and quantitative flow cytometry: a prospective study

scientific article published on 13 September 2007

Validation of flow cytometric phospho-STAT5 as a diagnostic tool for juvenile myelomonocytic leukemia

scientific article published on 15 November 2013

Value of cytogenetics in the differential diagnosis of the small round cell tumors of childhood.

scientific article published in January 1992

Vanillic Acid Restores Coenzyme Q Biosynthesis and ATP Production in Human Cells Lacking COQ6

scientific article published on 10 July 2019

Vascular disrupting activity of combretastatin analogues

scientific article published on 25 May 2016

WT1 loss attenuates the TP53-induced DNA damage response in T-cell acute lymphoblastic leukemia

scientific article published on 23 November 2017

WT1 mutations in T-ALL

scientific article published on 03 June 2009

What is the relevance of Ikaros gene deletions as a prognostic marker in pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia?

scientific article published on 12 April 2013

Whole transcriptome sequencing of a paediatric case of de novo acute myeloid leukaemia with del(5q) reveals RUNX1-USP42 and PRDM16-SKI fusion transcripts

scientific article published on 27 March 2014

Xenografts of Pediatric Acute Lymphoblastic Leukemia Retain the Gene Expression Pattern From the Diagnostic Material They Originated From Over Serial Passages. ⬇️

scholarly article

YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response

scientific article

ZNF521 Is a Zinc Finger Protein That Prevents Differentiation Of Human MLL-AF9-Positive Myeloid Leukemic Cells ⬇️

scholarly article

ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia.

scientific article published on 16 February 2017

Zebrafish Ortholog of Human DOT1L Regulates Primitive and Transient Definitive Hematopoiesis and Controls hoxa9 and meis1 Expression ⬇️

scholarly article

cAMP response element binding protein (CREB) overexpression CREB has been described as critical for leukemia progression

scientific article published on 01 October 2007

hCOX18 and hCOX19: two human genes involved in cytochrome c oxidase assembly

scientific article

miR-34b targets cyclic AMP-responsive element binding protein in acute myeloid leukemia

scientific article

mll ortholog containing functional domains of human MLL is expressed throughout the zebrafish lifespan and in haematopoietic tissues

scientific article

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