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List of works by Juan Méndez

A Proteomic Characterization of Factors Enriched at Nascent DNA Molecules

scientific article published on March 28, 2013

A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells.

scientific article published on 15 February 2016

An aspartic acid residue in TPR-1, a specific region of protein-priming DNA polymerases, is required for the functional interaction with primer terminal protein

scientific article published on 01 December 2000

CDC6: from DNA replication to cell cycle checkpoints and oncogenesis

scientific article

Cdc45-MCM-GINS, a new power player for DNA replication.

scientific article

Cell proliferation without cyclin E-CDK2

scientific article published on 01 August 2003

Cohesin organizes chromatin loops at DNA replication factories.

scientific article

DNA replication stress: from molecular mechanisms to human disease

scientific article

Deregulated expression of Cdc6 in the skin facilitates papilloma formation and affects the hair growth cycle.

scientific article published on December 2015

Deregulation of cyclin E in human cells interferes with prereplication complex assembly

scientific article

Dynamics of pre-replication complex proteins during the cell division cycle

scientific article

Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication.

scholarly article

Functional reprogramming of polyploidization in megakaryocytes

scientific article

Genomic stability and tumour suppression by the APC/C cofactor Cdh1.

scientific article

Initiation of phi 29 DNA replication occurs at the second 3' nucleotide of the linear template: a sliding-back mechanism for protein-primed DNA replication.

scientific article published on October 1992

In Vivo DNA Re-replication Elicits Lethal Tissue Dysplasias

scientific article published in May 2017

Molecular architecture of a multifunctional MCM complex

scientific article

Molecular architecture of the human GINS complex.

scientific article

Molecular architecture of the recombinant human MCM2-7 helicase in complex with nucleotides and DNA.

scientific article published on June 2016

NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity

scientific article

PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection

scientific article published on 22 November 2019

POLD3 Is Haploinsufficient for DNA Replication in Mice.

scientific article published on 11 August 2016

Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins

scientific article published on December 2003

PrimPol, an archaic primase/polymerase operating in human cells

scientific article

PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts

scientific article published on 17 November 2020

PrimPol-mediated repriming facilitates replication traverse of DNA interstrand crosslinks

scientific article published on 15 June 2021

Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality

scientific article

Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells

scientific article published on 30 July 2014

Repriming of DNA synthesis at stalled replication forks by human PrimPol

scientific article

Shortage of dNTPs underlies altered replication dynamics and DNA breakage in the absence of the APC/C cofactor Cdh1.

scientific article published on 12 June 2017

Structural and functional studies on ø29 DNA polymerase

scientific article published on 01 January 1992

Temporal regulation of DNA replication in mammalian cells.

scientific article published on September 2009

The human GINS complex associates with Cdc45 and MCM and is essential for DNA replication

scientific article published on 17 February 2009

USP7 is a SUMO deubiquitinase essential for DNA replication

scientific article (publication date: April 2016)

Uncoupling fork speed and origin activity to identify the primary cause of replicative stress phenotypes

scientific article published on 29 June 2018

Visualization of the MCM DNA helicase at replication factories before the onset of DNA synthesis

scientific article published on August 22, 2012