List of works - Pierre Legrand

A new highly integrated sample environment for protein crystallography.

scientific article

A unique ferrous iron binding mode is associated with large conformational changes for the transport protein FpvC of Pseudomonas aeruginosa

scientific article published on 26 July 2019

An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity

scientific article published on 27 July 2020

Assembly of infectious Kaposi's sarcoma-associated herpesvirus progeny requires formation of a pORF19 pentamer

scientific article published on 04 November 2021

Atomic view of the histidine environment stabilizing higher-pH conformations of pH-dependent proteins

scientific article published on 20 July 2015

Biochemical characterization and crystal structure of Synechocystis arogenate dehydrogenase provide insights into catalytic reaction

scientific article published on 01 April 2006

Biophysical and structural characterization of a zinc-responsive repressor of the MarR superfamily

scientific article published on 12 February 2019

ComFC mediates transport and handling of single-stranded DNA during natural transformation

scientific article published on 12 April 2022

Comparison of crystal structures of human type 3 3alpha-hydroxysteroid dehydrogenase reveals an "induced-fit" mechanism and a conserved basic motif involved in the binding of androgen.

scientific article published in June 2005

Crystal structure of Apis mellifera OBP14, a C-minus odorant-binding protein, and its complexes with odorant molecules

scientific article

Crystal structure of Mokola virus glycoprotein in its post-fusion conformation

scientific article published on 09 March 2020

Crystal structure of the 14-subunit RNA polymerase I

scientific article

Crystal structure of the prefusion surface glycoprotein of the prototypic arenavirus LCMV

scientific article published on 25 April 2016

Crystallization of the pectate lyase PelI from Erwinia chrysanthemi and SAD phasing of a gold derivative

scientific article published on 18 December 2003

Crystallographic snapshots of a B<sub>12</sub>-dependent radical SAM methyltransferase

scientific article published on 02 February 2022

Dual functions of the Hsm3 protein in chaperoning and scaffolding regulatory particle subunits during the proteasome assembly

scientific article

Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes

scientific article published on 13 August 2018

Expression, crystallization and preliminary X-ray analysis of human and rabbit 20alpha-hydroxysteroid dehydrogenases in complex with NADP(H) and various steroid substrates.

scientific article published on 21 December 2001

High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation

scientific article published on 28 February 2020

Import pathways of the mannityl-opines into the bacterial pathogen Agrobacterium tumefaciens: structural, affinity and in vivo approaches

scientific article published on 01 February 2020

Instrumentation for synchrotron-radiation macromolecular crystallography

scientific article

MXCuBE2: the dawn of MXCuBE Collaboration

scientific article published on 22 February 2019

Molecular basis of Diamond Blackfan anemia: structure and function analysis of RPS19

scientific article

Mutation of ribosomal protein RPS24 in Diamond-Blackfan anemia results in a ribosome biogenesis disorder

scientific article

Natural Guided Genome Engineering Reveals Transcriptional Regulators Controlling Quorum-Sensing Signal Degradation

scientific article

Nonredox thiolation in tRNA occurring via sulfur activation by a [4Fe-4S] cluster

scientific article published on 27 June 2017

Oncogenic activation of RET by two distinct FMTC mutations affecting the tyrosine kinase domain.

scientific article published on July 1997

Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines

scientific article

Priming and polymerization of a bacterial contractile tail structure

scientific article

Role of aspartate 70 and tryptophan 82 in binding of succinyldithiocholine to human butyrylcholinesterase

scientific article published on 01 February 1997

Species-Specific Functional Regions of the Green Alga Gamete Fusion Protein HAP2 Revealed by Structural Studies

article

Sqt1p is an eight-bladed WD40 protein.

scientific article published on January 2016

Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family

scientific article published in Scientific Reports

Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution

scientific article published on 08 December 2020

Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein.

scientific article published on 12 March 2018

Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining

scientific article

Structural characterization of the human androgen receptor ligand-binding domain complexed with EM5744, a rationally designed steroidal ligand bearing a bulky chain directed toward helix 12

scientific article

Structural insight into magnetochrome-mediated magnetite biomineralization

scientific article

Structural studies of the catalytic core of the primate foamy virus (PFV-1) integrase

scientific article

Structure and allosteric inhibition of excitatory amino acid transporter 1.

scientific article published on 19 April 2017

Structure and specificity of the Type VI secretion system ClpV-TssC interaction in enteroaggregative Escherichia coli.

scientific article published on 04 October 2016

Structure of the MutLα C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site

scientific article

Structure of the phage TP901-1 1.8 MDa baseplate suggests an alternative host adhesion mechanism

scientific article

Structure of the τ60/Δτ91 Subcomplex of Yeast Transcription Factor IIIC: Insights into Preinitiation Complex Assembly

scientific article published on 01 October 2006

Structure-function analysis of hRPC62 provides insights into RNA polymerase III transcription initiation

scientific article

Study of the DnaB:DciA interplay reveals insights into the primary mode of loading of the bacterial replicative helicase

scientific article published on 01 June 2021

Synergy between extracellular modules of vascular endothelial cadherin promotes homotypic hexameric interactions

scientific article

The Crystal Structure of Gurmarin, a Sweet Taste-Suppressing Protein: Identification of the Amino Acid Residues Essential for Inhibition

scientific article published on 01 September 2018

The crystal structure of the 5΄ functional domain of the transcription riboregulator 7SK.

scientific article

The structure of the CstF-77 homodimer provides insights into CstF assembly

scientific article

Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex

scientific article published on 26 June 2017

XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining

scientific article published on 05 October 2018

List of works by Pierre Legrand

A new highly integrated sample environment for protein crystallography.

A unique ferrous iron binding mode is associated with large conformational changes for the transport protein FpvC of Pseudomonas aeruginosa

An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity

Assembly of infectious Kaposi's sarcoma-associated herpesvirus progeny requires formation of a pORF19 pentamer

Atomic view of the histidine environment stabilizing higher-pH conformations of pH-dependent proteins

Biochemical characterization and crystal structure of Synechocystis arogenate dehydrogenase provide insights into catalytic reaction

Biophysical and structural characterization of a zinc-responsive repressor of the MarR superfamily

ComFC mediates transport and handling of single-stranded DNA during natural transformation

Comparison of crystal structures of human type 3 3alpha-hydroxysteroid dehydrogenase reveals an "induced-fit" mechanism and a conserved basic motif involved in the binding of androgen.

Crystal structure of Apis mellifera OBP14, a C-minus odorant-binding protein, and its complexes with odorant molecules

Crystal structure of Mokola virus glycoprotein in its post-fusion conformation

Crystal structure of the 14-subunit RNA polymerase I

Crystal structure of the prefusion surface glycoprotein of the prototypic arenavirus LCMV

Crystallization of the pectate lyase PelI from Erwinia chrysanthemi and SAD phasing of a gold derivative

Crystallographic snapshots of a B<sub>12</sub>-dependent radical SAM methyltransferase

Dual functions of the Hsm3 protein in chaperoning and scaffolding regulatory particle subunits during the proteasome assembly

Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes

Expression, crystallization and preliminary X-ray analysis of human and rabbit 20alpha-hydroxysteroid dehydrogenases in complex with NADP(H) and various steroid substrates.

High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation

Import pathways of the mannityl-opines into the bacterial pathogen Agrobacterium tumefaciens: structural, affinity and in vivo approaches

Instrumentation for synchrotron-radiation macromolecular crystallography

MXCuBE2: the dawn of MXCuBE Collaboration

Molecular basis of Diamond Blackfan anemia: structure and function analysis of RPS19

Mutation of ribosomal protein RPS24 in Diamond-Blackfan anemia results in a ribosome biogenesis disorder

Natural Guided Genome Engineering Reveals Transcriptional Regulators Controlling Quorum-Sensing Signal Degradation

Nonredox thiolation in tRNA occurring via sulfur activation by a [4Fe-4S] cluster

Oncogenic activation of RET by two distinct FMTC mutations affecting the tyrosine kinase domain.

Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines

Priming and polymerization of a bacterial contractile tail structure

Role of aspartate 70 and tryptophan 82 in binding of succinyldithiocholine to human butyrylcholinesterase

Species-Specific Functional Regions of the Green Alga Gamete Fusion Protein HAP2 Revealed by Structural Studies

Sqt1p is an eight-bladed WD40 protein.

Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family

Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution

Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein.

Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining

Structural characterization of the human androgen receptor ligand-binding domain complexed with EM5744, a rationally designed steroidal ligand bearing a bulky chain directed toward helix 12

Structural insight into magnetochrome-mediated magnetite biomineralization

Structural studies of the catalytic core of the primate foamy virus (PFV-1) integrase

Structure and allosteric inhibition of excitatory amino acid transporter 1.

Structure and specificity of the Type VI secretion system ClpV-TssC interaction in enteroaggregative Escherichia coli.

Structure of the MutLα C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site

Structure of the phage TP901-1 1.8 MDa baseplate suggests an alternative host adhesion mechanism

Structure of the τ60/Δτ91 Subcomplex of Yeast Transcription Factor IIIC: Insights into Preinitiation Complex Assembly

Structure-function analysis of hRPC62 provides insights into RNA polymerase III transcription initiation

Study of the DnaB:DciA interplay reveals insights into the primary mode of loading of the bacterial replicative helicase

Synergy between extracellular modules of vascular endothelial cadherin promotes homotypic hexameric interactions

The Crystal Structure of Gurmarin, a Sweet Taste-Suppressing Protein: Identification of the Amino Acid Residues Essential for Inhibition

The crystal structure of the 5΄ functional domain of the transcription riboregulator 7SK.

The structure of the CstF-77 homodimer provides insights into CstF assembly

Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex

XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining