List of works by Paul J Thornalley

A fluorogenic assay for methylglyoxal

scientific article published on April 2014

A mechanism for primaquine mediated oxidation of NADPH in red blood cells

scientific article published on 01 December 1983

A simplified method for the purification of human red blood cell glyoxalase. I. Characteristics, immunoblotting, and inhibitor studies

scientific article published on 01 April 1993

Accumulation of free adduct glycation, oxidation, and nitration products follows acute loss of renal function

scientific article published on 29 August 2007

Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease

scientific article

Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal.

scientific article published on 27 May 2019

Activity, regulation, copy number and function in the glyoxalase system

scientific article published on April 2014

Advanced glycation end products in extracellular matrix proteins contribute to the failure of sensory nerve regeneration in diabetes

scientific article published on 31 August 2009

Advanced glycation end products in renal failure

scientific article published on July 2006

Advanced glycation end products in the pathogenesis of chronic kidney disease

scientific article published on 22 February 2018

Advanced glycation endproducts, dityrosine and arginine transporter dysfunction in autism - a source of biomarkers for clinical diagnosis

scientific article published on 19 February 2018

Advances in glyoxalase research. Glyoxalase expression in malignancy, anti-proliferative effects of methylglyoxal, glyoxalase I inhibitor diesters and S-D-lactoylglutathione, and methylglyoxal-modified protein binding and endocytosis by the advanced

scientific article

Aging-Dependent Reduction in Glyoxalase 1 Delays Wound Healing

scientific article published on 22 June 2013

Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress

scientific article

Amino Acids Glycation Section

scientific article published on 01 April 2012

An EPR study of the production of superoxide radicals by neutrophil NADPH oxidase

scientific article published on 01 August 1982

Analysis of glucosinolates, isothiocyanates, and amine degradation products in vegetable extracts and blood plasma by LC-MS/MS.

scientific article

Antimalarial activity in vitro of the glyoxalase I inhibitor diester, S-p-bromobenzylglutathione diethyl ester.

scientific article

Antitumor Activity ofS-(p-Bromobenzyl)glutathione Diestersin Vitro: A Structure−Activity Study

scientific article published on 01 August 1996

Antitumour activity of S-p-bromobenzylglutathione cyclopentyl diester in vitro and in vivo

scientific article published on 01 May 1996

Antitumour activity of sphingoid base adducts of phenethyl isothiocyanate.

scientific article

Are brain and heart tissue prone to the development of thiamine deficiency?

scientific article

Arginine-directed glycation and decreased HDL plasma concentration and functionality

scientific article

Assay of 3-nitrotyrosine in tissues and body fluids by liquid chromatography with tandem mass spectrometric detection

scientific article published on January 2008

Assay of advanced glycation endproducts in selected beverages and food by liquid chromatography with tandem mass spectrometric detection

scientific article published in July 2005

Assay of early and advanced glycation adducts by enzymatic hydrolysis of proteins and HPLC of 6-aminoquinolylcarbonyl adducts

Assay of methylglyoxal and glyoxal and control of peroxidase interference

scientific article published on April 2014

Assay of methylglyoxal-derived protein and nucleotide AGEs

scientific article published on 01 April 2014

Benfotiamine protects against peritoneal and kidney damage in peritoneal dialysis

scientific article published on 21 April 2011

Biomarkers of early stage osteoarthritis, rheumatoid arthritis and musculoskeletal health

scientific article

C. elegans as model for the study of high glucose- mediated life span reduction

scientific article published on 12 August 2009

Characteristics of the inhibition of human promyelocytic leukaemia HL60 cell growth by S-d-lactoylglutathione in vitro

scientific article published on 01 April 1993

Comparison of the delivery of reduced glutathione into P388D1 cells by reduced glutathione and its mono- and diethyl ester derivatives

scientific article published on 01 May 1995

Copy number variation of glyoxalase I.

scientific article published on April 2014

Correction to: Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease.

scientific article

Degradation products of proteins damaged by glycation, oxidation and nitration in clinical type 1 diabetes.

scientific article published on 30 June 2005

Detection of 3-deoxyglucosone-derived AGE structures in vitro

Detection of oxidized and glycated proteins in clinical samples using mass spectrometry--a user's perspective

scientific article

Determination of Types and Binding Sites of Advanced Glycation End Products for Substance P

scientific article published on 05 December 2012

Diabetes is associated with posttranslational modifications in plasminogen resulting in reduced plasmin generation and enzyme-specific activity

scientific article published on 22 May 2013

Dicarbonyl intermediates in the maillard reaction

scientific article published in June 2005

Dicarbonyl proteome and genome damage in metabolic and vascular disease

scientific article published on April 2014

Dicarbonyl stress in cell and tissue dysfunction contributing to ageing and disease

scientific article

Dicarbonyl stress in clinical obesity

scientific article published on 24 June 2016

Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics

scientific article published on 12 July 2016

Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress

scientific article published on October 2008

Dietary AGEs and ALEs and risk to human health by their interaction with the receptor for advanced glycation endproducts (RAGE)--an introduction

scientific article published on September 2007

Dietary and synthetic activators of the antistress gene response in treatment of renal disease

scientific article published on January 2012

Differential effects of glyoxalase 1 overexpression on diabetic atherosclerosis and renal dysfunction in streptozotocin-treated, apolipoprotein E-deficient mice

scientific article

Disturbance of B-vitamin status in people with type 2 diabetes in Indonesia--link to renal status, glycemic control and vascular inflammation

scientific article

Effect of Irbesartan treatment on plasma and urinary markers of protein damage in patients with type 2 diabetes and microalbuminuria

scientific article published on 08 March 2011

Effect of methylglyoxal on human leukaemia 60 cell growth: Modification of DNA, G1 growth arrest and induction of apoptosis

scientific article published on 01 May 1996

Effect of storage, processing and cooking on glucosinolate content of Brassica vegetables

scientific article

Effects of Methylglyoxal on Rat Pancreatic β-Cells

scientific article published on 01 May 1998

Enhanced production of hydroxyl radicals by the xanthine-xanthine oxidase reaction in the presence of lactoferrin

scientific article published on 01 March 1982

Erratum: Corrigendum: Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

scholarly article published in Nature Medicine

Estimation of α-oxoaldehydes formed from the degradation of glycolytic intermediates and glucose fragmentation in blood plasma of human subjects with uraemia

Evidence against the formation of 2-amino-6-(2-formyl-5-hydroxymethyl-pyrrol-l-yl)-hexanoic acid ('pyrraline') as an early-stage product or advanced glycation end product in non-enzymic protein glycation

article

Facile synthesis of (R)N-2-hydroxyacyl-L-cysteine derivatives: (R)N-2-hydroxyacyl transfer from enzymatically-synthesized (R)S-2-hydroxyacylglutathione derivatives to L-cysteine

scientific article published on 01 June 1995

Factors influencing the development and effectiveness of biomarkers in rheumatoid arthritis and osteoarthritis

article

Fluorimetric assay of D-lactate

scientific article (publication date: October 1992)

Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose

scientific article

Free radical involvement in the oxidate phenomena induced by tert-butyl hydroperoxide in erythrocytes

scientific article published on 01 August 1983

Free radical production from normal and adriamycin-treated rat cardiac sarcosomes

article

Free radical production from the aerobic oxidation of reduced pyridine nucleotides catalysed by phenazine derivatives

article

Frequency Modulated Translocational Oscillations of Nrf2 Mediate the Antioxidant Response Element Cytoprotective Transcriptional Response.

scientific article

Frequency modulated translocational oscillations of Nrf2, a transcription factor functioning like a wireless sensor

scientific article published on 03 August 2015

GLO1-A novel amplified gene in human cancer

scientific article

Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes

scientific article

Glutathione-dependent detoxification of alpha-oxoaldehydes by the glyoxalase system: involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors.

scientific article published in April 1998

Glycated and oxidized protein degradation products are indicators of fasting and postprandial hyperglycemia in diabetes

scientific article published in October 2005

Glycation free adduct accumulation in renal disease: the new AGE.

scientific article published on 24 August 2005

Glycation marker glucosepane increases with the progression of osteoarthritis and correlates with morphological and functional changes of cartilage in vivo.

scientific article published on 22 June 2018

Glycation of LDL by methylglyoxal increases arterial atherogenicity: a possible contributor to increased risk of cardiovascular disease in diabetes

scientific article

Glycation research in amino acids: a place to call home

scientific article published on April 2012

Glycation, receptor-mediated cell activation and vascular complications of diabetes

scientific article published on 01 May 2004

Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer

scientific article published on 01 October 2020

Glyoxalase 1 copy number variation in patients with well differentiated gastro-entero-pancreatic neuroendocrine tumours (GEP-NET).

scientific article published on 16 August 2017

Glyoxalase 1-knockdown in human aortic endothelial cells - effect on the proteome and endothelial function estimates

scientific article published on 29 November 2016

Glyoxalase Centennial conference: introduction, history of research on the glyoxalase system and future prospects

scientific article published on April 2014

Glyoxalase II does not support methylglyoxal detoxification but serves as a general trypanothione thioesterase in African trypanosomes

scientific article published on 19 September 2008

Glyoxalase System in Clinical Diabetes Mellitus and Correlation with Diabetic Complications

scientific article published on 01 July 1994

Glyoxalase activity during differentiation of human leukaemia cells in vitro

scientific article published on 01 January 1987

Glyoxalase activity in human red blood cells fractioned by age

scientific article published on 01 April 1989

Glyoxalase in ageing

scientific article published on 12 February 2011

Glyoxalase in diabetes, obesity and related disorders

scientific article published on 16 February 2011

Glyoxalase in tumourigenesis and multidrug resistance

scientific article published on 18 February 2011

Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans

scientific article published on 21 January 2008

Hidden Complexities in the Measurement of Fructosyl-Lysine and Advanced Glycation End Products for Risk Prediction of Vascular Complications of Diabetes: Figure 1

scientific article published on 01 January 2015

High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A

scientific journal article

High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease

scientific article

High-dose thiamine therapy counters dyslipidaemia in streptozotocin-induced diabetic rats.

scientific article published on 11 December 2004

High-dose thiamine therapy counters dyslipidemia and advanced glycation of plasma protein in streptozotocin-induced diabetic rats

scientific article published in June 2005

High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a randomised, double-blind placebo-controlled pilot study.

scientific article

Highlights and hotspots of protein glycation in end-stage renal disease

scientific article published on July 2009

Human serum albumin minimally modified by methylglyoxal binds to human mononuclear leukocytes via the RAGE receptor and is displaced by Nε-carboxymethyl-lysine and hydroimidazolone AGE epitopes

Hyperglycemic kidney damage in an animal model of prolonged critical illness.

scientific article

Idiopathic hypoalbuminemia explained by reduced synthesis rate and an increased catabolic rate.

scientific article

Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance

scientific article

Improved Glycemic Control and Vascular Function in Overweight and Obese Subjects by Glyoxalase 1 Inducer Formulation.

scientific article published on 11 May 2016

Increased DNA dicarbonyl glycation and oxidation markers in patients with type 2 diabetes and link to diabetic nephropathy

scientific article published on 9 April 2015

Increased dicarbonyl metabolism in endothelial cells in hyperglycemia induces anoikis and impairs angiogenesis by RGD and GFOGER motif modification

scientific article published on July 2006

Increased formation of methylglyoxal and protein glycation, oxidation and nitrosation in triosephosphate isomerase deficiency

scientific article published in October 2003

Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin

scientific article

Increased protein glycation in cirrhosis and therapeutic strategies to prevent it.

scientific article published in June 2005

Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes.

scientific article published in February 2003

Induction of synthesis and secretion of interleukin 1β in the human monocytic THP-1 cells by human serum albumins modified with methylglyoxal and advanced glycation endproducts

scientific article published on 01 April 1996

Inhibition of Glyoxalase I (EC4.4.1.5)

Inhibition of growth of human leukaemia 60 cells by S-2-hydroxyacylglutathiones and monoethyl ester derivatives

scientific article published in November 1992

Inhibition of human leukaemia 60 cell growth by mercapturic acid metabolites of phenylethyl isothiocyanate

scientific article published on 01 April 1996

Inhibition of proliferation of human leukaemia 60 cells by diethyl esters of glyoxalase inhibitors in vitro

scientific article published on December 15, 1992

Inhibition of proliferation of human promyelocytic leukaemia HL60 cells by S-d-lactoylglutathione in vitro

scientific article published on 01 January 1988

Inhibitors of glyoxalase I: Design, synthesis, inhibitory characteristics and biological evaluation

scientific article published on 01 May 1993

Intracellular Accumulation of Methylglyoxal by Glyoxalase 1 Knock Down Alters Collagen Homoeostasis in L6 Myoblasts

scientific article published on 23 February 2017

Involvement of a gut-retina axis in protection against dietary glycemia-induced age-related macular degeneration.

scientific article published on 15 May 2017

Isothiocyanates: mechanism of cancer chemopreventive action

scientific article

Kinetics and mechanism of the reaction of aminoguanidine with the alpha-oxoaldehydes glyoxal, methylglyoxal, and 3-deoxyglucosone under physiological conditions.

scientific article published in July 2000

Kinetics and mechanism of the reaction of metformin with methylglyoxal

Mass spectrometric determination of early and advanced glycation in biology

scientific article published on 20 July 2016

Measurement of glyoxalase activities

scientific article

Measurement of glyoxalase gene expression

scientific article published on April 2014

Measurement of methylglyoxal by stable isotopic dilution analysis LC-MS/MS with corroborative prediction in physiological samples

scientific article

Mechanism of the degradation of non-enzymatically glycated proteins under physiological conditions. Studies with the model fructosamine, N epsilon-(1-deoxy-D-fructos-1-yl)hippuryl-lysine.

scientific article published in December 1992

Methylglyoxal Modification of mSin3A Links Glycolysis to Angiopoietin-2 Transcription

scientific article published on 01 February 2007

Methylglyoxal administration induces diabetes-like microvascular changes and perturbs the healing process of cutaneous wounds.

scientific article

Methylglyoxal modification of LDL: proatherogenicity without oxidation opens new paths to prevent cardiovascular disease

Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

scientific article

Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription

scientific article published on 12 January 2006

Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome

scientific article published on 21 October 2010

Methylglyoxal, glyoxalases and the development of diabetic complications

scientific article published in February 1994

Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins

scientific article published in December 2003

Methylglyoxal-induced dicarbonyl stress in aging and disease: first steps towards glyoxalase 1-based treatments

scientific article

Methylglyoxal-modified arginine residues — a signal for receptor-mediated endocytosis and degradation of proteins by monocytic THP-1 cells

scientific article published on 01 March 1997

Modification of the glyoxalase system in disease processes and prospects for therapeutic strategies.

scientific article

Modification of the glyoxalase system in human HL60 promyelocytic leukemia cells during differentiation to neutrophils in vitro

scientific article published on 01 September 1988

Modification of the glyoxalase system in streptozotocin-induced diabetic rats

scientific article published on 01 September 1993

Molecular characteristics of methylglyoxal-modified bovine and human serum albumins. Comparison with glucose-derived advanced glycation endproduct-modified serum albumins

scientific article published on 01 July 1995

Multiple roles of glyoxalase 1-mediated suppression of methylglyoxal glycation in cancer biology-Involvement in tumour suppression, tumour growth, multidrug resistance and target for chemotherapy.

scientific article

Negative Association between Erythrocyte Reduced Glutathione Concentration and Diabetic Complications

scientific article published on 01 November 1996

Nepsilon-(Carboxymethyl)lysine and 3-DG-imidazolone are major AGE structures in protein modification by 3-deoxyglucosone

scientific article published in September 2004

New development in a blood-based diagnostic test for early-stage arthritis.

scientific article published on 6 October 2015

Novel anti-glycation therapeutic agents: glyoxalase I mimetics

Optimisation of non-denaturing polyacrylamide gel electrophoretic analysis of glyoxalase I phenotypes in clinical blood samples

scientific article published on 01 December 1991

Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis

scientific article

Oxygen restriction as challenge test reveals early high-fat-diet-induced changes in glucose and lipid metabolism

scientific article published in July 2014

Peptide mapping identifies hotspot site of modification in human serum albumin by methylglyoxal involved in ligand binding and esterase activity

scientific article published on 22 November 2004

Peptide mapping of human serum albumin modified minimally by methylglyoxal in vitro and in vivo

scientific article published in June 2005

Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy.

scientific article published on June 1996

Phenyl radical production during the oxidation of phenylhydrazine and in phenylphydrazine-induced haemolysis

scientific article published on 01 March 1981

Population genetics of human glyoxalases ⬇️

scientific article published on October 1, 1991

Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals

scientific article published on 01 January 1985

Possible role of methylglyoxal and glyoxalase in arthritis

scientific article published on April 2014

Preparation and characterisation of N epsilon-(1-deoxy-D-fructos-1-yl)hippuryl-lysine

scientific article published on January 1, 1992

Preparation of nucleotide advanced glycation endproducts--imidazopurinone adducts formed by glycation of deoxyguanosine with glyoxal and methylglyoxal

scientific article published in April 2008

Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine

scientific article (publication date: August 2003)

Processing of protein glycation, oxidation and nitrosation adducts in the liver and the effect of cirrhosis

scientific article published in December 2004

Profound mishandling of protein glycation degradation products in uremia and dialysis.

scientific article

Protein and nucleotide damage by glyoxal and methylglyoxal in physiological systems--role in ageing and disease

scientific article published on January 2008

Protein damage in diabetes and uremia--identifying hotspots of proteome damage where minimal modification is amplified to marked pathophysiological effect

scientific article

Protein glycation, oxidation and nitration adduct residues and free adducts of cerebrospinal fluid in Alzheimer's disease and link to cognitive impairment

scientific article published in January 2005

Protein oxidation, nitration and glycation biomarkers for early-stage diagnosis of osteoarthritis of the knee and typing and progression of arthritic disease

scientific article published on 27 October 2016

Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease ⬇️

scientific article published on 14 February 2018

Purification and characterisation of glyoxalase II from human red blood cells

scientific article published on 01 May 1993

Purification of major glucosinolates fromBrassicaceae seeds and preparation of isothiocyanate and amine metabolites

Quantitation of plasma thiamine, related metabolites and plasma protein oxidative damage markers in children with autism spectrum disorder and healthy controls

scientific article published on 25 September 2016

Quantitative measurement of specific biomarkers for protein oxidation, nitration and glycation in Arabidopsis leaves.

scientific article published on 25 April 2009

Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry

scientific article published on November 2003

Rapid hydrolysis and slow α,β-dicarbonyl cleavage of an agent proposed to cleave glucose-derived protein cross-links

scientific article published on 01 February 1999

Reaction kinetics of the scavenging of α-oxoaldehydes by aminoguanidine under physiological conditions

Reappraisal of putative glyoxalase 1-deficient mouse and dicarbonyl stress on embryonic stem cells in vitro.

scientific article

Relation of the protein glycation, oxidation and nitration to the osteocalcin level in obese subjects.

scientific article published on 28 July 2017

Reversal of hyperglycemia-induced angiogenesis deficit of human endothelial cells by overexpression of glyoxalase 1 in vitro

scientific article published on April 2008

Review on uraemic toxins III: recommendations for handling uraemic retention solutes in vitro towards a standardized approach for research on uraemia

scientific article published on 27 August 2007

S-D-lactoylglutathione in resting and activated human neutrophils.

scientific article published in June 1987

Sample Storage Conditions for the Assay of Glyoxalase Activities in Whole Blood Samples

scientific article published on 01 March 1992

Serum levels of advanced glycation endproducts and other markers of protein damage in early diabetic nephropathy in type 1 diabetes

scientific article

Severe thiamine deficiency complicated by weight loss protects against renal ischaemia-reperfusion injury in rats.

scientific article published on April 2009

Special edition of Amino Acids of selected papers from the eleventh international symposium on the Maillard reaction, September 16-20, 2012.

scientific article

Stimulation of Suicidal Erythrocyte Death by Methylglyoxal

scientific article published on 01 January 2006

Studies of advanced glycation end products and oxidation biomarkers for type 2 diabetes

scientific article published on 02 May 2018

Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro.

scientific article published in July 2000

Study of an Unusual Advanced Glycation End-Product (AGE) Derived from Glyoxal Using Mass Spectrometry

scientific article published on 28 January 2014

Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage

scientific article published on 22 November 2018

Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro.

scientific article

Synthesis and secretion of macrophage colony stimulating factor by mature human monocytes and human monocytic THP-1 cells induced by human serum albumin derivatives modified with methylglyoxal and glucose-derived advanced glycation endproducts

scientific article published on 01 October 1996

Synthesis and secretion of tumour necrosis factor-alpha by human monocytic THP-1 cells and chemotaxis induced by human serum albumin derivatives modified with methylglyoxal and glucose-derived advanced glycation endproducts.

scientific article

The Assay of S-D-Lactoylglutathione in Biological Systems

scientific article published on 01 May 1993

The Critical Role of Methylglyoxal and Glyoxalase 1 in Diabetic Nephropathy

scientific article published on 01 January 2014

The Effect of Nitrone Spin Trapping Agents on Red Cell Glucose Metabolism

scientific article published on 01 January 1985

The assay of methylglyoxal in biological systems byderivatization with 1,2-diamino-4,5-dimethoxybenzene

scientific article published on 01 October 1992

The autoxidation of glyceraldehyde and other simple monosaccharides under physiological conditions catalysed by buffer ions

scientific article published on 01 February 1984

The dicarbonyl proteome: proteins susceptible to dicarbonyl glycation at functional sites in health, aging, and disease

scientific article published in April 2008

The effect of glyceraldehyde on red cells

scientific article published on 01 July 1984

The effect of spin traps on phenylhydrazine-induced haemolysis

scientific article published on 01 February 1983

The formation of active oxygen species following activation of 1-naphthol, 1,2- and 1,4-naphthoquinone by rat liver microsomes ⬇️

scientific article published on February 1, 1984

The formation of methylglyoxal from triose phosphates. Investigation using a specific assay for methylglyoxal.

scientific article

The generation of hydroxyl radicals following superoxide production by neutrophil NADPH oxidase.

scientific article published in December 1982

The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life

scientific article

The glyoxalase system—From microbial metabolism, through ageing to human disease and multidrug resistance

scientific article published on 18 February 2011

The haemolytic reactions of 1-acetyl-2-phenylhydrazine and hydrazine: A spin trapping study

scientific article published on 01 August 1984

The human red blood cell glyoxalase system in diabetes mellitus.

scientific article

The oxidation of oxyhaemoglobin by glyceraldehyde and other simple monosaccharides.

scientific article published on February 1984

The production of free radicals during the autoxidation of cysteine and their effect on isolated rat hepatocytes

scientific article published on 01 October 1982

The production of free radicals during the autoxidation of monosaccharides by buffer ions

article

The production of hydroxyl radicals by adriamycin in red blood cells

scientific article published on 01 June 1983

The production of oxygen-centered radicals by Bacillus-Calmette-Guerin-activated macrophages

article

The reaction of methylglyoxal with aminoguanidine under physiological conditions and prevention of methylglyoxal binding to plasma proteins.

scientific article published on November 1994

The role of EUTox in uremic toxin research

scientific article published on July 2009

The uremic toxin oxythiamine causes functional thiamine deficiency in end-stage renal disease by inhibiting transketolase activity

scientific article published on 14 May 2016

Therapy: Vitamin B6, B9 and B12 in diabetic nephropathy--beware

scientific article published on September 2010

Tissue-specific glucose toxicity induces mitochondrial damage in a burn injury model of critical illness

scientific article published in April 2009

Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

scientific article

Unease on the role of glyoxalase 1 in high-anxiety-related behaviour

scientific article

Unraveling the biological roles of reactive oxygen species

scientific article published on April 2011

Urinary Metabolomic Markers of Protein Glycation, Oxidation, and Nitration in Early-Stage Decline in Metabolic, Vascular, and Renal Health

scientific article published on 19 November 2019

Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts ⬇️

scientific article published on November 1, 2003

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