List of works - Giuliana Guggino

Activated IL-22 pathway occurs in the muscle tissues of patients with polymyositis or dermatomyositis and is correlated with disease activity

scientific article published on 05 March 2014

Adult-onset Still's disease: evaluation of prognostic tools and validation of the systemic score by analysis of 100 cases from three centers

scientific article

Advances in immunopathogenesis of macrophage activation syndrome during rheumatic inflammatory diseases: toward new therapeutic targets?

scientific article published on 24 August 2017

An intense physical rehabilitation programme determines pain relief and improves the global quality of life in patients with fibromyalgia

scientific article published on 20 May 2019

Are Toll-like receptors and decoy receptors involved in the immunopathogenesis of systemic lupus erythematosus and lupus-like syndromes?

scientific article published on 16 August 2011

Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: a new potential target for antifibrotic therapy

scientific article published on 03 October 2018

Brief Report: Functional Interaction of Endoplasmic Reticulum Aminopeptidase 2 and HLA-B27 Activates the Unfolded Protein Response

scientific article published on 28 December 2016

CD3 immunohistochemistry is helpful in the diagnosis of giant cell arteritis

scientific article published on 01 August 2018

CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren's syndrome patients and correlates with focus score and disease activity

scientific article

Cardiovascular Disease in Primary Sjögren's Syndrome

scientific article published on 01 January 2018

Clinical efficacy of α4 integrin block with natalizumab in ankylosing spondylitis.

scientific article

Colchicine as possible treatment of non-cryoglobulinaemic vasculitis in Sjögren's syndrome

scientific article published on 18 March 2020

Difference in the expression of IL-9 and IL-17 correlates with different histological pattern of vascular wall injury in giant cell arteritis

scientific article published on 09 April 2015

Downregulation of miRNA17-92 cluster marks Vγ9Vδ2 T cells from patients with rheumatoid arthritis

article

Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis.

scientific article published on 9 January 2017

Ectopic expression of CXCL13, BAFF, APRIL and LT-β is associated with artery tertiary lymphoid organs in giant cell arteritis.

scientific article published on 20 April 2016

Efficacy and safety of γδT cell-based tumor immunotherapy: a meta-analysis

article by S Buccheri et al published 1 January 2014 in Journal of Biological Regulators and Homeostatic Agents

Endothelial progenitor cells: Are they displaying a function in autoimmune disorders?

scientific article published on 3 May 2016

Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation

scientific article published on 05 June 2013

Expression of interleukin-32 in the inflamed arteries of patients with giant cell arteritis.

scientific article

Ferritin and C-reactive protein are predictive biomarkers of mortality and macrophage activation syndrome in adult onset Still's disease. Analysis of the multicentre Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale (GIRRCS) cohort

scientific article published on 09 July 2020

Functional Signatures of Human CD4 and CD8 T Cell Responses to Mycobacterium tuberculosis

scientific article

Gammadelta T cell modulation in anticancer treatment.

scientific article published on February 2010

Genome-based in silico identification of new Mycobacterium tuberculosis antigens activating polyfunctional CD8+ T cells in human tuberculosis

scientific article published on 17 December 2010

Granzyme A as a potential biomarker of Mycobacterium tuberculosis infection and disease

scientific article published on 5 June 2015

Guidelines for biomarkers in autoimmune rheumatic diseases - evidence based analysis

scientific article published on 05 November 2018

Gut inflammation in spondyloarthritis

scientific article published on 01 December 2017

Gut-derived CD8+ tissue-resident memory T cells are expanded in the peripheral blood and synovia of SpA patients

scientific article published on 18 October 2019

H-ferritin and CD68(+) /H-ferritin(+) monocytes/macrophages are increased in the skin of adult-onset Still's disease patients and correlate with the multi-visceral involvement of the disease.

scientific article published on 18 June 2016

H-ferritin and proinflammatory cytokines are increased in the bone marrow of patients affected by macrophage activation syndrome.

scientific article published on 28 September 2017

HLA-C1 ligands are associated with increased susceptibility to systemic lupus erythematosus

scientific article published on 23 January 2018

Histopathology of the gut in rheumatic diseases

scientific article published on 03 October 2018

Hyaluronic acid and platelet-rich plasma, a new therapeutic alternative for scleroderma patients: a prospective open-label study

scientific article published on 13 December 2019

IL-17 polarization of MAIT cells is derived from the activation of two different pathways.

scientific article published on 16 August 2017

IL-1β at the crossroad between rheumatoid arthritis and type 2 diabetes: may we kill two birds with one stone?

scientific article

IL-25 axis is involved in the pathogenesis of human primary and experimental Sjögren's syndrome.

scientific article published on 23 March 2018

IL-33 is overexpressed in the inflamed arteries of patients with giant cell arteritis.

scientific article

IL-34 is overexpressed in the inflamed salivary glands of patients with Sjogren's syndrome and is associated with the local expansion of pro-inflammatory CD14(bright)CD16+ monocytes

scientific article published on 07 February 2013

Impact of immunosuppressive drugs on the therapeutic efficacy of ex vivo expanded human regulatory T cells

scientific article

In vivo manipulation of Vgamma9Vdelta2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients

scientific article published on 10 May 2010

Increased expression of interleukin-32 in the inflamed ileum of ankylosing spondylitis patients

scientific article published on 30 July 2012

Increased percentages of calprotectin and TNF-Α double-positive monocytes in the acute phase of Kawasaki disease

scientific article published on 14 September 2011

Interleukin (IL)-22 receptor 1 is over-expressed in primary Sjogren's syndrome and Sjögren-associated non-Hodgkin lymphomas and is regulated by IL-18.

scientific article

Interleukin (IL)-9/IL-9R axis drives γδ T cells activation in psoriatic arthritis patients

scientific article published on 20 August 2016

Interleukin-17 Inhibition in Spondyloarthritis Is Associated With Subclinical Gut Microbiome Perturbations and a Distinctive Interleukin-25-Driven Intestinal Inflammation

scientific article published on 12 March 2020

Interleukin-32 in systemic sclerosis, a potential new biomarker for pulmonary arterial hypertension

scientific article published on 01 June 2020

Interleukin-36α axis is modulated in patients with primary Sjögren's syndrome.

scientific article published on 3 June 2015

Interleukin-9 Overexpression and Th9 Polarization Characterize the Inflamed Gut, the Synovial Tissue, and the Peripheral Blood of Patients With Psoriatic Arthritis

scientific article published on 01 August 2016

Interleukin-9 and T helper type 9 cells in rheumatic diseases.

scientific article published on 9 May 2016

Interleukin-9 over-expression and T helper 9 polarization in systemic sclerosis patients.

scientific article

Interstitial lung disease in systemic sclerosis: current and future treatment

scientific article published on 6 January 2017

Invariant NKT Cells and Rheumatic Disease: Focus on Primary Sjogren Syndrome ⬇️

scientific article published on 31 October 2019

Invariant NKT cells are expanded in peripheral blood but are undetectable in salivary glands of patients with primary Sjögren's syndrome.

scientific article published in December 2015

Invariant natural killer T cells treated with rapamycin or transforming growth factor-β acquire a regulatory function and suppress T effector lymphocytes.

scientific article

Macrophage phenotype in the subclinical gut inflammation of patients with ankylosing spondylitis

scientific article

Managing Adult-onset Still's disease: The effectiveness of high-dosage of corticosteroids as first-line treatment in inducing the clinical remission. Results from an observational study

Mesenchymal stem cells of Systemic Sclerosis patients, derived from different sources, show a profibrotic microRNA profiling

scientific article published on 09 May 2019

Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection

scientific article published in August 2010

New insights into the pathogenesis of giant cell arteritis

scientific article published on 4 May 2017

New tools for detecting latent tuberculosis infection: evaluation of RD1-specific long-term response

scientific article

Non-conventional forms of HLA-B27 are expressed in spondyloarthritis joints and gut tissue.

scientific article published on 29 March 2016

Parenchymal lung disease in adult onset Still's disease: an emergent marker of disease severity-characterisation and predictive factors from Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale (GIRRCS) cohort of patients

scientific article published on 22 June 2020

Pathogenesis of polymyalgia rheumatica

scientific article published on 27 March 2018

Peripheral frequency of CD4+ CD28- cells in acute ischemic stroke: relationship with stroke subtype and severity markers

scientific article

Perivascular Cells in Diffuse Cutaneous Systemic Sclerosis Overexpress Activated ADAM12 and Are Involved in Myofibroblast Transdifferentiation and Development of Fibrosis.

scientific article published in June 2016

Pharmacological stress, rest perfusion and delayed enhancement cardiac magnetic resonance identifies very early cardiac involvement in systemic sclerosis patients of recent onset.

scientific article published on 4 June 2017

Phenotypical and functional analysis of memory and effector human CD8 T cells specific for mycobacterial antigens

scientific article published in August 2006

Potential involvement of IL-22 and IL-22-producing cells in the inflamed salivary glands of patients with Sjogren's syndrome.

scientific article

Potential involvement of IL-9 and Th9 cells in the pathogenesis of rheumatoid arthritis

scientific article published on 15 July 2015

Predominance of Type 1 Innate Lymphoid Cells in the Rectal Mucosa of Patients With Non-Celiac Wheat Sensitivity: Reversal After a Wheat-Free Diet.

scientific article published on 7 July 2016

Prevalence of type 2 diabetes and impaired fasting glucose in patients affected by rheumatoid arthritis: Results from a cross-sectional study.

scientific article

Primary Sjogren Syndrome: Focus on Innate Immune Cells and Inflammation

scientific article published on 03 June 2020

Prognostic factors of macrophage activation syndrome, at the time of diagnosis, in adult patients affected by autoimmune disease: Analysis of 41 cases collected in 2 rheumatologic centers.

scientific article published on 21 September 2016

Proinflammatory CX3CR1+CD59+Tumor Necrosis Factor-Like Molecule 1A+Interleukin-23+ Monocytes Are Expanded in Patients With Ankylosing Spondylitis and Modulate Innate Lymphoid Cell 3 Immune Functions

scientific article published on 01 December 2018

Reply

Reply to: Safety and efficacy of secukinumab treatment in a patient with ankylosing spondylitis and concomitant multiple sclerosis: a commentary

scientific article published on 20 May 2020

Retracted: Analysis of Mycobacterium tuberculosis-Specific CD8 T-Cells in Patients with Active Tuberculosis and in Individuals with Latent Infection

retracted article

Retracted: Carboxyamidotriazole-Orotate Inhibits the Growth of Imatinib-Resistant Chronic Myeloid Leukaemia Cells and Modulates Exosomes-Stimulated Angiogenesis

retracted article

Rituximab modulates IL-17 expression in the salivary glands of patients with primary Sjögren’s syndrome

scientific article published on 06 March 2014

Rituximab modulates the expression of IL-22 in the salivary glands of patients with primary Sjogren's syndrome

scientific article published on 21 December 2012

Role of Subclinical Gut Inflammation in the Pathogenesis of Spondyloarthritis.

scientific article published in May 2018

Safety and efficacy of secukinumab treatment in a patient with ankylosing spondylitis and concomitant multiple sclerosis

scientific article published on 28 June 2019

Sclerostin and Antisclerostin Antibody Serum Levels Predict the Presence of Axial Spondyloarthritis in Patients with Inflammatory Bowel Disease

scientific article

Secukinumab efficacy in patients with PsA is not dependent on patients' body mass index

scientific article published on 13 March 2020

Subclinical and clinical atherosclerosis in rheumatoid arthritis: results from the 3-year, multicentre, prospective, observational GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) study

scientific article published on 03 September 2019

T helper 1 response is correlated with widespread pain, fatigue, sleeping disorders and the quality of life in patients with fibromyalgia and is modulated by hyperbaric oxygen therapy

scientific article published on 01 January 2019

Targeting IL-6 signalling in early rheumatoid arthritis is followed by Th1 and Th17 suppression and Th2 expansion

scholarly article by Giuliana Guggino et al published 14 January 2014 in Clinical and Experimental Rheumatology

The CD68(+)/H-ferritin(+) cells colonize the lymph nodes of the patients with adult onset Still's disease and are associated with increased extracellular level of H-ferritin in the same tissue: correlation with disease severity and implication for p

scientific article published on 5 November 2015

The Janus Face of NKT Cell Function in Autoimmunity and Infectious Diseases

scientific article published in February 2018

The emerging role of IL-1 inhibition in patients affected by rheumatoid arthritis and diabetes

scientific article published on 13 March 2018

The in vitro addition of methotrexate and/or methylprednisolone determines peripheral reduction in Th17 and expansion of conventional Treg and of IL-10 producing Th17 lymphocytes in patients with early rheumatoid arthritis

scientific article published on 03 May 2014

The role of innate and lymphoid IL-22-producing cells in the immunopathology of primary Sjögren's syndrome.

scientific article published on 04 February 2014

The role of the gastrointestinal tract in the pathogenesis of rheumatic diseases

scientific article published on October 2016

Timing of activation of CD4+ memory cells as a possible marker to establish the efficacy of vaccines against contagious agalactia in sheep

scientific article published on 29 December 2012

Tocilizumab therapy for unresponsive pulmonary arterial hypertension in a patient with Takayasu arteritis

scientific article published on 01 January 2016

Tuning inflammation in tuberculosis: the role of decoy receptors.

scientific article published on 18 May 2009

Type 3 innate lymphoid cells producing IL-17 and IL-22 are expanded in the gut, in the peripheral blood, synovial fluid and bone marrow of patients with ankylosing spondylitis.

scientific article published on 22 April 2015

Uncoupling protein 2 as genetic risk factor for Systemic Lupus Erythematosus: association with malondialdehyde levels and intima media thickness

scientific article published on 01 June 2020

V gamma 9V delta 2 T lymphocytes efficiently recognize and kill zoledronate-sensitized, imatinib-sensitive, and imatinib-resistant chronic myelogenous leukemia cells.

scientific article published on 12 February 2010

Vitamin D increases the production of IL-10 by regulatory T cells in patients with systemic sclerosis

scientific article published on 01 July 2019

List of works by Giuliana Guggino

Activated IL-22 pathway occurs in the muscle tissues of patients with polymyositis or dermatomyositis and is correlated with disease activity

Adult-onset Still's disease: evaluation of prognostic tools and validation of the systemic score by analysis of 100 cases from three centers

Advances in immunopathogenesis of macrophage activation syndrome during rheumatic inflammatory diseases: toward new therapeutic targets?

An intense physical rehabilitation programme determines pain relief and improves the global quality of life in patients with fibromyalgia

Are Toll-like receptors and decoy receptors involved in the immunopathogenesis of systemic lupus erythematosus and lupus-like syndromes?

Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: a new potential target for antifibrotic therapy

Brief Report: Functional Interaction of Endoplasmic Reticulum Aminopeptidase 2 and HLA-B27 Activates the Unfolded Protein Response

CD3 immunohistochemistry is helpful in the diagnosis of giant cell arteritis

CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren's syndrome patients and correlates with focus score and disease activity

Cardiovascular Disease in Primary Sjögren's Syndrome

Clinical efficacy of α4 integrin block with natalizumab in ankylosing spondylitis.

Colchicine as possible treatment of non-cryoglobulinaemic vasculitis in Sjögren's syndrome

Difference in the expression of IL-9 and IL-17 correlates with different histological pattern of vascular wall injury in giant cell arteritis

Downregulation of miRNA17-92 cluster marks Vγ9Vδ2 T cells from patients with rheumatoid arthritis

Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis.

Ectopic expression of CXCL13, BAFF, APRIL and LT-β is associated with artery tertiary lymphoid organs in giant cell arteritis.

Efficacy and safety of γδT cell-based tumor immunotherapy: a meta-analysis

Endothelial progenitor cells: Are they displaying a function in autoimmune disorders?

Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation

Expression of interleukin-32 in the inflamed arteries of patients with giant cell arteritis.

Ferritin and C-reactive protein are predictive biomarkers of mortality and macrophage activation syndrome in adult onset Still's disease. Analysis of the multicentre Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale (GIRRCS) cohort

Functional Signatures of Human CD4 and CD8 T Cell Responses to Mycobacterium tuberculosis

Gammadelta T cell modulation in anticancer treatment.

Genome-based in silico identification of new Mycobacterium tuberculosis antigens activating polyfunctional CD8+ T cells in human tuberculosis

Granzyme A as a potential biomarker of Mycobacterium tuberculosis infection and disease

Guidelines for biomarkers in autoimmune rheumatic diseases - evidence based analysis

Gut inflammation in spondyloarthritis

Gut-derived CD8+ tissue-resident memory T cells are expanded in the peripheral blood and synovia of SpA patients

H-ferritin and CD68(+) /H-ferritin(+) monocytes/macrophages are increased in the skin of adult-onset Still's disease patients and correlate with the multi-visceral involvement of the disease.

H-ferritin and proinflammatory cytokines are increased in the bone marrow of patients affected by macrophage activation syndrome.

HLA-C1 ligands are associated with increased susceptibility to systemic lupus erythematosus

Histopathology of the gut in rheumatic diseases

Hyaluronic acid and platelet-rich plasma, a new therapeutic alternative for scleroderma patients: a prospective open-label study

IL-17 polarization of MAIT cells is derived from the activation of two different pathways.

IL-1β at the crossroad between rheumatoid arthritis and type 2 diabetes: may we kill two birds with one stone?

IL-25 axis is involved in the pathogenesis of human primary and experimental Sjögren's syndrome.

IL-33 is overexpressed in the inflamed arteries of patients with giant cell arteritis.

IL-34 is overexpressed in the inflamed salivary glands of patients with Sjogren's syndrome and is associated with the local expansion of pro-inflammatory CD14(bright)CD16+ monocytes

Impact of immunosuppressive drugs on the therapeutic efficacy of ex vivo expanded human regulatory T cells

In vivo manipulation of Vgamma9Vdelta2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients

Increased expression of interleukin-32 in the inflamed ileum of ankylosing spondylitis patients

Increased percentages of calprotectin and TNF-Α double-positive monocytes in the acute phase of Kawasaki disease

Interleukin (IL)-22 receptor 1 is over-expressed in primary Sjogren's syndrome and Sjögren-associated non-Hodgkin lymphomas and is regulated by IL-18.

Interleukin (IL)-9/IL-9R axis drives γδ T cells activation in psoriatic arthritis patients

Interleukin-17 Inhibition in Spondyloarthritis Is Associated With Subclinical Gut Microbiome Perturbations and a Distinctive Interleukin-25-Driven Intestinal Inflammation

Interleukin-32 in systemic sclerosis, a potential new biomarker for pulmonary arterial hypertension

Interleukin-36α axis is modulated in patients with primary Sjögren's syndrome.

Interleukin-9 Overexpression and Th9 Polarization Characterize the Inflamed Gut, the Synovial Tissue, and the Peripheral Blood of Patients With Psoriatic Arthritis

Interleukin-9 and T helper type 9 cells in rheumatic diseases.

Interleukin-9 over-expression and T helper 9 polarization in systemic sclerosis patients.

Interstitial lung disease in systemic sclerosis: current and future treatment

Invariant NKT Cells and Rheumatic Disease: Focus on Primary Sjogren Syndrome ⬇️

Invariant NKT cells are expanded in peripheral blood but are undetectable in salivary glands of patients with primary Sjögren's syndrome.

Invariant natural killer T cells treated with rapamycin or transforming growth factor-β acquire a regulatory function and suppress T effector lymphocytes.

Macrophage phenotype in the subclinical gut inflammation of patients with ankylosing spondylitis

Managing Adult-onset Still's disease: The effectiveness of high-dosage of corticosteroids as first-line treatment in inducing the clinical remission. Results from an observational study

Mesenchymal stem cells of Systemic Sclerosis patients, derived from different sources, show a profibrotic microRNA profiling

Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection

New insights into the pathogenesis of giant cell arteritis

New tools for detecting latent tuberculosis infection: evaluation of RD1-specific long-term response

Non-conventional forms of HLA-B27 are expressed in spondyloarthritis joints and gut tissue.

Parenchymal lung disease in adult onset Still's disease: an emergent marker of disease severity-characterisation and predictive factors from Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale (GIRRCS) cohort of patients

Pathogenesis of polymyalgia rheumatica

Peripheral frequency of CD4+ CD28- cells in acute ischemic stroke: relationship with stroke subtype and severity markers

Perivascular Cells in Diffuse Cutaneous Systemic Sclerosis Overexpress Activated ADAM12 and Are Involved in Myofibroblast Transdifferentiation and Development of Fibrosis.

Pharmacological stress, rest perfusion and delayed enhancement cardiac magnetic resonance identifies very early cardiac involvement in systemic sclerosis patients of recent onset.

Phenotypical and functional analysis of memory and effector human CD8 T cells specific for mycobacterial antigens

Potential involvement of IL-22 and IL-22-producing cells in the inflamed salivary glands of patients with Sjogren's syndrome.

Potential involvement of IL-9 and Th9 cells in the pathogenesis of rheumatoid arthritis

Predominance of Type 1 Innate Lymphoid Cells in the Rectal Mucosa of Patients With Non-Celiac Wheat Sensitivity: Reversal After a Wheat-Free Diet.

Prevalence of type 2 diabetes and impaired fasting glucose in patients affected by rheumatoid arthritis: Results from a cross-sectional study.

Primary Sjogren Syndrome: Focus on Innate Immune Cells and Inflammation

Prognostic factors of macrophage activation syndrome, at the time of diagnosis, in adult patients affected by autoimmune disease: Analysis of 41 cases collected in 2 rheumatologic centers.

Proinflammatory CX3CR1+CD59+Tumor Necrosis Factor-Like Molecule 1A+Interleukin-23+ Monocytes Are Expanded in Patients With Ankylosing Spondylitis and Modulate Innate Lymphoid Cell 3 Immune Functions

Reply

Reply to: Safety and efficacy of secukinumab treatment in a patient with ankylosing spondylitis and concomitant multiple sclerosis: a commentary

Retracted: Analysis of Mycobacterium tuberculosis-Specific CD8 T-Cells in Patients with Active Tuberculosis and in Individuals with Latent Infection

Retracted: Carboxyamidotriazole-Orotate Inhibits the Growth of Imatinib-Resistant Chronic Myeloid Leukaemia Cells and Modulates Exosomes-Stimulated Angiogenesis

Rituximab modulates IL-17 expression in the salivary glands of patients with primary Sjögren’s syndrome