List of works by Chun Geun Lee

A chitinase-like protein in the lung and circulation of patients with severe asthma

scientific article

Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells

scientific article

Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway

scientific article published on August 2003

Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis

scientific article

Airway inflammation and remodeling in asthma. Lessons from interleukin 11 and interleukin 13 transgenic mice.

scientific article published in November 2001

Antifibrotic role of vascular endothelial growth factor in pulmonary fibrosis.

scientific article

Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury

scientific article

Breast Regression Protein-39/Chitinase 3-Like 1 Promotes Renal Fibrosis after Kidney Injury via Activation of Myofibroblasts

scientific article published on 5 July 2017

COPD as a Disease of Immunosenescence

scientific article published on 01 May 2019

Chitin is a size-dependent regulator of macrophage TNF and IL-10 production

scientific article

Chitin particles are multifaceted immune adjuvants

scientific article

Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection

scientific article published on 12 March 2015

Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3

scientific article published on 13 May 2019

Chitinase 3-Like 1 Contributes to Food Allergy via M2 Macrophage Polarization

scientific article published on 01 November 2020

Chitinase 3-like 1 is induced by Plasmodium falciparum malaria and predicts outcome of cerebral malaria and severe malarial anaemia in a case-control study of African children

scientific article

Chitinase 3-like 1 protein plays a critical role in respiratory syncytial virus-induced airway inflammation

scholarly article by Min Jung Kim et al published 4 December 2018 in Allergy

Chitinase 3-like 1 regulates cellular and tissue responses via IL-13 receptor α2

scientific article published on 22 August 2013

Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis

scientific article

Chitinase 3-like 1 synergistically activates IL6-mediated STAT3 phosphorylation in intestinal epithelial cells in murine models of infectious colitis

scientific article

Chitinase 3-like-1 Promotes Intrahepatic Activation of Coagulation Through Induction of Tissue Factor in Mice.

scientific article

Chitinase 3-like-1 contributes to the development of pulmonary vascular remodeling in pulmonary hypertension

scientific article published in 2022

Chitinase 3-like-1 regulates both visceral fat accumulation and asthma-like Th2 inflammation.

scientific article published on April 2015

Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma

scientific article

Chitotriosidase in the Pathogenesis of Inflammation, Interstitial Lung Diseases and COPD

scientific article

Chitotriosidase inhibits allergic asthmatic airways via regulation of TGF-β expression and Foxp3+ Treg cells

scientific article published on 8 February 2018

Conditional overexpression of bioactive transforming growth factor-beta1 in neonatal mouse lung: a new model for bronchopulmonary dysplasia?

scientific article published on 27 August 2004

Corrigendum: IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses

scientific article published on 14 November 2016

Cytokine regulation of IL-13Ralpha2 and IL-13Ralpha1 in vivo and in vitro

scientific article published in April 2003

Developmental regulation of NO-mediated VEGF-induced effects in the lung

scientific article published on 25 April 2008

Differential expression of chitinases identify subsets of murine airway epithelial cells in allergic inflammation

scientific article published on 23 March 2006

Distal airways are protected from goblet cell metaplasia by diminished expression of IL-13 signalling components

scientific article published on 14 March 2015

ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo

scientific article

Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis

scientific article

Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production

scientific article published on 10 July 2008

Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor-beta1 in pulmonary fibrosis

scientific article published on 18 March 2015

Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung

scholarly article

Genetic control of transforming growth factor-beta1-induced emphysema and fibrosis in the murine lung

scientific article published in August 2006

Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death

scientific article

IFN-gamma-dependent DNA injury and/or apoptosis are critical in cigarette smoke-induced murine emphysema

scientific article published in August 2006

IL-11 receptor alpha in the pathogenesis of IL-13-induced inflammation and remodeling.

scientific article published in February 2005

IL-11 selectively inhibits aeroallergen-induced pulmonary eosinophilia and Th2 cytokine production.

scientific article published in August 2000

IL-12-STAT4-IFN-gamma axis is a key downstream pathway in the development of IL-13-mediated asthma phenotypes in a Th2 type asthma model

scientific article published on August 2010

IL-13 in asthma. The successful integration of lessons from mice and humans.

scientific article published in April 2011

IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension

scientific article published on 2 November 2012

IL-13 stimulates vascular endothelial cell growth factor and protects against hyperoxic acute lung injury.

scientific article

IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses

scientific article published on 15 September 2016

IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation

scientific article published in February 2007

Immunomodulation of Host Chitinase 3-Like 1 During a Mammary Pathogenic Escherichia coli Infection.

scientific article published on 28 May 2018

Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle.

scientific article published on 18 August 2009

Interleukin-13 and leukotrienes: an intersection of pathogenetic schema.

scientific article

Lipid let loose in pulmonary emphysema.

scientific article published in May 2005

Lung vascular endothelial growth factor expression induces local myeloid dendritic cell activation.

scientific article published on 24 June 2009

Matrix Metalloproteinase-Targeted Imaging of Lung Inflammation and Remodeling

scientific article published on 28 July 2016

Modern concepts on the role of inflammation in pulmonary fibrosis

scientific article published on June 2011

Neuropilin-1 regulates vascular endothelial growth factor-mediated endothelial permeability.

scientific article published on 26 May 2005

New insights into the pathogenesis of asthma

article

Novel biomarkers in asthma: chemokines and chitinase-like proteins

scientific article published on February 2009

P21 regulates TGF-beta1-induced pulmonary responses via a TNF-alpha-signaling pathway

scientific article published on 11 October 2007

Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations

scientific article published on 28 October 2005

Phospholipid scramblase-1 regulates innate type 2 inflammation in mouse lungs via CRTH2-dependent mechanisms

scientific article published in 2023

Pulmonary expression of leukemia inhibitory factor induces B cell hyperplasia and confers protection in hyperoxia

scientific article published on 2 June 2003

RIG-like helicase innate immunity inhibits vascular endothelial growth factor tissue responses via a type I IFN-dependent mechanism

scientific article published on 28 January 2011

Recombinant basic fibroblast growth factor inhibits the airway hyperresponsiveness, mucus production, and lung inflammation induced by an allergen challenge.

scientific article published on 7 February 2007

Regulated angiogenesis and vascular regression in mice overexpressing vascular endothelial growth factor in airways.

scientific article

Regulation and Role of Chitotriosidase during Lung Infection withKlebsiella pneumoniae

scientific article published on 11 June 2018

Regulation of Retinoic Acid Receptor Beta by Interleukin-15 in the Lung during Cigarette Smoking and Influenza Virus Infection

scientific article published on 29 April 2015

Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis.

scientific article

Role of 5-lipoxygenase in IL-13-induced pulmonary inflammation and remodeling

scientific article

Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema

scientific article

Role of Chitinase 3-Like-1 in Interleukin-18-Induced Pulmonary Type 1, Type 2, and Type 17 Inflammation; Alveolar Destruction; and Airway Fibrosis in the Murine Lung

scientific article published on 8 May 2015

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis

scientific article published on 04 May 2009

Role of breast regression protein-39 in the pathogenesis of cigarette smoke-induced inflammation and emphysema

scientific article

Role of cathepsin S-dependent epithelial cell apoptosis in IFN-gamma-induced alveolar remodeling and pulmonary emphysema

scientific article published in June 2005

Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury.

scientific article published on January 2011

Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling

scientific article published on 26 January 2006

Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis

scientific article

Sputum Gene Expression of IL-13 Receptor α2 Chain Correlates with Airflow Obstruction and Helper T-Cell Type 2 Inflammation in Asthma

scientific article published on March 2016

State of the art. Mechanistic heterogeneity in chronic obstructive pulmonary disease: insights from transgenic mice

scientific article published on August 2006

Suppression of NLRX1 in chronic obstructive pulmonary disease

scientific article published on 4 May 2015

TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation.

scientific article published on September 2008

Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling

scientific article

The chitinase-like proteins breast regression protein-39 and YKL-40 regulate hyperoxia-induced acute lung injury.

scientific article

Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12.

scientific article published on 5 January 2007

Transgenic modeling of interleukin-13 in the lung.

scientific article

Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling

scientific article

Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways

scientific article

VEGF controls lung Th2 inflammation via the miR-1-Mpl (myeloproliferative leukemia virus oncogene)-P-selectin axis.

scientific article published on 16 September 2013

Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung.

scientific article

Vascular endothelial growth factor enhances macrophage clearance of apoptotic cells.

scientific article published on 3 February 2012

YKL-40, a chitinase-like protein at the intersection of inflammation and remodeling.

scientific article published in April 2012

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