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List of works by Jean-Christophe Bourdon

A distinct p53 protein isoform signature reflects the onset of induction chemotherapy for acute myeloid leukemia

scientific article published on 01 July 2006

Adenosine deaminase, a key enzyme in DNA precursors control, is a new p73 target.

scientific article published on November 2003

Biological functions of p53 isoforms through evolution: lessons from animal and cellular models.

scientific article published on 23 September 2011

Cdc25B is negatively regulated by p53 through Sp1 and NF-Y transcription factors.

scientific article published on 17 January 2011

DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability

scientific article

Detecting p53 Isoforms at Protein Level

scientific article published on January 1, 2013

Direct transactivation of c-Ha-Ras gene by p53: evidence for its involvement in p53 transactivation activity and p53-mediated apoptosis

scientific article published on 01 November 2000

Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation

scientific article

Expression of P53 and isoforms in bening and malignant lesions of the head and neck.

scientific article published on 14 July 2016

Expression of TP53 isoforms p53β or p53γ enhances chemosensitivity in TP53(null) cell lines.

scientific article

Immunoreactions for P53 isoforms are associated with ultrastructural proliferative profiles in benign thyroid nodules.

scientific article published on 16 February 2016

Influenza A viruses alter the stability and antiviral contribution of host E3-ubiquitin ligase Mdm2 during the time-course of infection

scientific article published on 27 February 2018

Influenza A viruses control expression of proviral human p53 isoforms p53β and Delta133p53α.

scientific article

Influenza NS1 interacts with p53 and alters its binding to p53-responsive genes, in a promoter-dependent manner.

scientific article published on 13 August 2013

Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma

scientific article published on 23 May 2011

Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity

scientific article

Modulation of p53β and p53γ expression by regulating the alternative splicing of TP53 gene modifies cellular response

scientific article

Mutant mice lacking the p53 C-terminal domain model telomere syndromes.

scientific article published on 13 June 2013

Physical and Chemical Processes and the Morphofunctional Characteristics of Human Erythrocytes in Hyperglycaemia

scientific article published on 30 August 2017

Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence.

scientific article

Primary cultured neurons devoid of cellular prion display lower responsiveness to staurosporine through the control of p53 at both transcriptional and post-transcriptional levels

scientific article published on 21 October 2003

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

scientific article

TP53 drives invasion through expression of its Δ133p53β variant

scientific article published on 15 September 2016

The RNA helicase p68 modulates expression and function of the Δ133 isoform(s) of p53, and is inversely associated with Δ133p53 expression in breast cancer

scientific article

The calcium binding protein ALG-2 binds and stabilizes Scotin, a p53-inducible gene product localized at the endoplasmic reticulum membrane

scientific article

The heparan sulfate sulfotransferase 3-OST3A (HS3ST3A) is a novel tumor regulator and a prognostic marker in breast cancer

scientific article published on 4 April 2016

The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression.

scientific article

The p53 isoforms are differentially modified by Mdm2.

scientific article

Transcriptional activation of tyrosinase and TRP-1 by p53 links UV irradiation to the protective tanning response

scientific article published on 01 January 2000

Tumor Susceptibility and Apoptosis Defect in a Mouse Strain Expressing a Human p53 Transgene

scientific article published on 15 March 2006

Uncovering the role of p53 splice variants in human malignancy: a clinical perspective

scientific article

What is the potential of p53 isoforms as a predictive biomarker in the treatment of cancer?

scientific article published on 07 January 2019

Wild-type p53 activates SAP expression in lymphoid cells.

scientific article published on November 2004

p53 Isoforms: An Intracellular Microprocessor?

scientific article

p53 Isoforms: Key Regulators of the Cell Fate Decision.

scientific article

p53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer.

scientific article published on September 2013

p53 directly transactivates Δ133p53α, regulating cell fate outcome in response to DNA damage

scientific article

p53 family members in cancer diagnosis and treatment.

scientific article published on February 2010

p53 is activated in response to disruption of the pre-mRNA splicing machinery.

scientific article

p53 isoform delta113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish.

scientific article published on February 2009

p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence

scientific article

p53 isoforms can regulate p53 transcriptional activity.

scientific article

p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients.

scientific article

p53 mutation, deprivation and poor prognosis in primary breast cancer

scientific article

p53 protein accumulation in European hepatocellular carcinoma is not always dependent on p53 gene mutation

scientific article published on 01 April 1995

p53-dependent repression of polo-like kinase-1 (PLK1).

scientific article published on 4 October 2010

p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.

scientific article

p53: 25 years of research and more questions to answer.

scientific article

Δ133p53β isoform pro-invasive activity is regulated through an aggregation-dependent mechanism in cancer cells

scientific article published on 15 September 2021

Δ160p53 is a novel N-terminal p53 isoform encoded by Δ133p53 transcript.

scientific article published on 13 October 2010