List of works - Ismail Syed

A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty acids

scientific article published on 17 March 2016

Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport

scientific article

Adipose tissue dysfunction is associated with low levels of the novel Palmitic Acid Hydroxystearic Acids

scientific article published in Scientific Reports

Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 β-cells and rat islets.

scientific article

Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase

scientific article

Curcumin, Hesperidin, and Rutin Selectively Interfere with Apoptosis Signaling and Attenuate Streptozotocin-Induced Oxidative Stress-Mediated Hyperglycemia

scientific article published on 12 August 2015

Data-driven synthesis of proteolysis-resistant peptide hormones

scientific article

Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects.

scientific article

Isoprenylcysteine carboxyl methyltransferase facilitates glucose-induced Rac1 activation, ROS generation and insulin secretion in INS 832/13 β-cells ⬇️

scientific article published on March 1, 2011

Matrix metalloproteinase-9, -10, and -12, MDM2 and p53 expression in mouse liver during dimethylnitrosamine-induced oxidative stress and genomic injury

scientific article published on 23 March 2012

Methodological Issues in Studying PAHSA Biology: Masking PAHSA Effects

scientific article published on 20 September 2018

Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance

scientific article published on 27 February 2017

PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice

scientific article published on 05 August 2019

Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis.

scientific article published in February 2018

Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1.

scientific article

Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells.

scientific article

RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance

scientific article

Rab-geranylgeranyl transferase regulates glucose-stimulated insulin secretion from pancreatic β cells ⬇️

scientific article published on September 1, 2012

Regulation of glucose- and mitochondrial fuel-induced insulin secretion by a cytosolic protein histidine phosphatase in pancreatic beta-cells

scientific article

Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation

scientific article published on 28 March 2017

TIAM1-RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy.

scientific article published on 20 February 2014

Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxides and lipid peroxides and the loss of mitochondrial membrane potential in pancreatic beta-cells.

scientific article

List of works by Ismail Syed

A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty acids

Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport

Adipose tissue dysfunction is associated with low levels of the novel Palmitic Acid Hydroxystearic Acids

Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 β-cells and rat islets.

Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase

Curcumin, Hesperidin, and Rutin Selectively Interfere with Apoptosis Signaling and Attenuate Streptozotocin-Induced Oxidative Stress-Mediated Hyperglycemia

Data-driven synthesis of proteolysis-resistant peptide hormones

Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects.

Isoprenylcysteine carboxyl methyltransferase facilitates glucose-induced Rac1 activation, ROS generation and insulin secretion in INS 832/13 β-cells ⬇️

Matrix metalloproteinase-9, -10, and -12, MDM2 and p53 expression in mouse liver during dimethylnitrosamine-induced oxidative stress and genomic injury

Methodological Issues in Studying PAHSA Biology: Masking PAHSA Effects

Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance

PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice

Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis.

Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1.

Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells.

RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance

Rab-geranylgeranyl transferase regulates glucose-stimulated insulin secretion from pancreatic β cells ⬇️

Regulation of glucose- and mitochondrial fuel-induced insulin secretion by a cytosolic protein histidine phosphatase in pancreatic beta-cells

Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation

TIAM1-RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy.

Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxides and lipid peroxides and the loss of mitochondrial membrane potential in pancreatic beta-cells.