List of works - Mark J Coster

3,4'-Linked bis(piperidines) related to the haliclonacyclamine class of marine alkaloids: synthesis using crossed-aldol chemistry and preliminary biological evaluations.

scientific article

A bidirectional synthesis of spiroacetals via Rh(ii)-catalysed C-H insertion

scientific article published on 01 April 2017

A concise route to dihydrobenzo[b]furans: formal total synthesis of (+)-lithospermic acid

scientific article published on 07 June 2011

Dichloro-naphthoquinone as a non-classical inhibitor of the mycobacterial carbonic anhydrase Rv3588c

scientific article published on 12 May 2017

Enzyme characteristics of pathogen-specific trehalose-6-phosphate phosphatases

scientific article

Evaluation of behavioural effects of a selective NMDA NR1A/2B receptor antagonist in the unilateral 6-OHDA lesion rat model.

scientific article published on 24 September 2008

Medium ring ethers by ring expansion-ring contraction: synthesis of lauthisan

scientific article published on 01 September 2002

Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II

scientific article

Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy

scientific article published on 12 March 2011

Mitochondrially targeted α-tocopheryl succinate is antiangiogenic: potential benefit against tumor angiogenesis but caution against wound healing

scientific article

Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling

scientific article published on 12 November 2009

Panel docking of small-molecule libraries - Prospects to improve efficiency of lead compound discovery

scientific article published on 27 May 2015

Probing function and structure of trehalose-6-phosphate phosphatases from pathogenic organisms suggests distinct molecular groupings

scientific article published on 18 November 2016

Purinergic P2X(7) receptor antagonists: Chemistry and fundamentals of biological screening.

scientific article published on 12 June 2009

Reversibility in the boron-mediated ketone-ketone aldol reaction

scientific article published on 22 January 2007

Rhodium(II)-catalysed intramolecular C-H insertion α- to oxygen: reactivity, selectivity and applications to natural product synthesis.

scientific article published on 12 May 2015

Selective cleavage of N-benzyl-protected secondary amines by triphosgene.

scientific article published in January 2003

Synthesis and Antiplasmodial Evaluation of Analogues Based on the Tricyclic Core of Thiaplakortones A-D.

scientific article

Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold

scientific article

Synthesis and biological evaluation of spongistatin/altohyrtin analogues: E-ring dehydration and C46 side-chain truncation.

scientific article

Synthesis and evaluation of anticancer natural product analogues based on angelmarin: targeting the tolerance towards nutrient deprivation.

scientific article

Synthesis of spirocyclic orthoesters by 'anomalous' rhodium(ii)-catalysed intramolecular C-H insertions

scientific article published on 14 December 2017

Targeting the resistance of pancreatic cancer cells to nutrient deprivation: anti-austerity compounds.

scientific article published on December 2010

The design, synthesis, and anti-inflammatory evaluation of a drug-like library based on the natural product valerenic acid.

scientific article

The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the AB-spiroacetal segment

scientific article published on 24 May 2005

The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the CD-spiroacetal segment

scientific article published on 24 May 2005

Total synthesis of (+)-angelmarin.

scientific article

Total synthesis of thiaplakortone a: derivatives as metabolically stable leads for the treatment of malaria

scientific article

Trishomocubanes: novel sigma ligands modulate cocaine-induced behavioural effects.

scientific article published on 18 October 2006

List of works by Mark J Coster

3,4'-Linked bis(piperidines) related to the haliclonacyclamine class of marine alkaloids: synthesis using crossed-aldol chemistry and preliminary biological evaluations.

A bidirectional synthesis of spiroacetals via Rh(ii)-catalysed C-H insertion

A concise route to dihydrobenzo[b]furans: formal total synthesis of (+)-lithospermic acid

Dichloro-naphthoquinone as a non-classical inhibitor of the mycobacterial carbonic anhydrase Rv3588c

Enzyme characteristics of pathogen-specific trehalose-6-phosphate phosphatases

Evaluation of behavioural effects of a selective NMDA NR1A/2B receptor antagonist in the unilateral 6-OHDA lesion rat model.

Medium ring ethers by ring expansion-ring contraction: synthesis of lauthisan

Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II

Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy

Mitochondrially targeted α-tocopheryl succinate is antiangiogenic: potential benefit against tumor angiogenesis but caution against wound healing

Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling

Panel docking of small-molecule libraries - Prospects to improve efficiency of lead compound discovery

Probing function and structure of trehalose-6-phosphate phosphatases from pathogenic organisms suggests distinct molecular groupings

Purinergic P2X(7) receptor antagonists: Chemistry and fundamentals of biological screening.

Reversibility in the boron-mediated ketone-ketone aldol reaction

Rhodium(II)-catalysed intramolecular C-H insertion α- to oxygen: reactivity, selectivity and applications to natural product synthesis.

Selective cleavage of N-benzyl-protected secondary amines by triphosgene.

Synthesis and Antiplasmodial Evaluation of Analogues Based on the Tricyclic Core of Thiaplakortones A-D.

Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold

Synthesis and biological evaluation of spongistatin/altohyrtin analogues: E-ring dehydration and C46 side-chain truncation.

Synthesis and evaluation of anticancer natural product analogues based on angelmarin: targeting the tolerance towards nutrient deprivation.

Synthesis of spirocyclic orthoesters by 'anomalous' rhodium(ii)-catalysed intramolecular C-H insertions

Targeting the resistance of pancreatic cancer cells to nutrient deprivation: anti-austerity compounds.

The design, synthesis, and anti-inflammatory evaluation of a drug-like library based on the natural product valerenic acid.

The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the AB-spiroacetal segment

The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the CD-spiroacetal segment

Total synthesis of (+)-angelmarin.

Total synthesis of thiaplakortone a: derivatives as metabolically stable leads for the treatment of malaria

Trishomocubanes: novel sigma ligands modulate cocaine-induced behavioural effects.