Search filters

List of works by Virginia Merino

A UHPLC-UV Method to Quantify Skin Deposition and Transdermal Permeation of Tizanidine Hydrochloride

scientific article published on 17 February 2016

A dopamine transport inhibitor with markedly low abuse liability suppresses cocaine self-administration in the rat.

scientific article published on 16 September 2009

A preclinical study to model taurine pharmokinetics in the undernourished rat.

scientific article published in April 2018

Antibiotic-loaded Bone Cement as Prophylaxis in Total Joint Replacement.

scientific article published in November 2017

Bioactivity of Ceftazidime and Fluconazole Included in Polymethyl Methacrylate Bone Cement for Use in Arthroplasty.

scientific article published on 4 May 2017

Bioadhesive monolayer film for the in vitro transdermal delivery of sumatriptan.

scientific article published in July 2006

Combination strategies for enhancing transdermal absorption of sumatriptan through skin

scientific article published on 02 June 2006

Controlled Iontophoretic Delivery in Vitro and in Vivo of ARN14140-A Multitarget Compound for Alzheimer's Disease

scientific article published on 05 July 2019

Controlled iontophoretic delivery of pramipexole: electrotransport kinetics in vitro and in vivo

scientific article published on 11 February 2014

Controlled iontophoretic transport of huperzine A across skin in vitro and in vivo: effect of delivery conditions and comparison of pharmacokinetic models.

scientific article

Controlled transdermal iontophoresis for poly-pharmacotherapy: Simultaneous delivery of granisetron, metoclopramide and dexamethasone sodium phosphate in vitro and in vivo

scientific article published on 28 January 2016

Design, characterization and in vitro evaluation of 5-aminosalicylic acid loaded N-succinyl-chitosan microparticles for colon specific delivery

scientific article published on 01 February 2012

Development and In Vitro Evaluation of Lyotropic Liquid Crystals for the Controlled Release of Dexamethasone

scientific article published on 02 August 2017

Development and evaluation of occlusive systems employing polyvinyl alcohol for transdermal delivery of sumatriptan succinate.

scientific article published in February 2010

Development of antibiotic loaded biodegradable matrices to prevent superficial infections associated to total knee arthroplasty

scientific article published on 11 May 2019

Development of antimigraine transdermal delivery systems of pizotifen malate.

scientific article published on 18 July 2015

Double Drug Delivery Using Capped Mesoporous Silica Microparticles for the Effective Treatment of Inflammatory Bowel Disease

scientific article published on 29 April 2019

Effect of chemical enhancers on the in vitro percutaneous absorption of sumatriptan succinate.

scientific article published in September 2005

Effect of iontophoresis on in vitro transdermal absorption of almotriptan.

scientific article published on 28 June 2011

Efficacy of budesonide-loaded mesoporous silica microparticles capped with a bulky azo derivative in rats with TNBS-induced colitis

scientific article published on 26 February 2019

Elastic vesicles of sumatriptan succinate for transdermal administration: characterization and in vitro permeation studies

scientific article published on 30 April 2010

Electrorepulsion versus electroosmosis: effect of pH on the iontophoretic flux of 5-fluorouracil

scientific article published on 01 May 1999

Enhancement of nortriptyline penetration through human epidermis: influence of chemical enhancers and iontophoresis.

scientific article published in April 2008

Functional Magnetic Mesoporous Silica Microparticles Capped with an Azo-Derivative: A Promising Colon Drug Delivery Device.

scientific article published on 10 February 2018

HPLC-UV analytical method for determination of pizotifen after in vitro transdermal diffusion studies

scientific article

Hydroxypropylmethylcellulose films for the ophthalmic delivery of diclofenac sodium.

scientific article published on 13 September 2012

Impact of Undernutrition on the Pharmacokinetics and Pharmacodynamics of Anticancer Drugs: A Literature Review

scientific article published on 29 March 2017

Impact of nutritional status on the pharmacokinetics of erlotinib in rats.

scientific article published on 12 March 2015

Improving oral bioavailability and pharmacokinetics of liposomal metformin by glycerolphosphate-chitosan microcomplexation.

scientific article published on 8 March 2013

In Situ Study of the Effect of Naringin, Talinolol and Protein-Energy Undernutrition on Intestinal Absorption of Saquinavir in Rats

scientific article published on 26 May 2011

Influence of Inter- and Intra-Batch Variability on the Sample Size Required for Demonstration of Equivalent Microstructure of Semisolid Dosage Forms

scientific article published on 28 November 2020

Influence of polyunsaturated fatty acids on Cortisol transport through MDCK and MDCK-MDR1 cells as blood-brain barrier in vitro model.

scientific article published on 21 December 2010

Intrinsic absolute bioavailability prediction in rats based on in situ absorption rate constants and/or in vitro partition coefficients: 6-fluoroquinolones.

scientific article published in November 2000

Ionic Hydrogel Based on Chitosan Cross-Linked with 6-Phosphogluconic Trisodium Salt as a Drug Delivery System.

scientific article published on 14 March 2018

Kinetic Modeling of Triamterene Intestinal Absorption and its Inhibition by Folic Acid and Methotrexate

scientific article published on May 1, 2003

Levofloxacin effect on erlotinib absorption. Evaluation of the interaction in undernutrition situations through population pharmacokinetic analysis in rats.

scientific article published on 18 January 2017

Mathematical modelling of in situ and in vitro efflux of ciprofloxacin and grepafloxacin.

scientific article published on 27 October 2005

Mesoporous silica microparticles gated with a bulky azo derivative for the controlled release of dyes/drugs in colon

scientific article published on 15 August 2018

N-Succinyl-chitosan systems for 5-aminosalicylic acid colon delivery: In vivo study with TNBS-induced colitis model in rats

scientific article published on 23 June 2011

New Insights of Oral Colonic Drug Delivery Systems for Inflammatory Bowel Disease Therapy

scientific article published on 05 September 2020

Noninvasive sampling of phenylalanine by reverse iontophoresis

scientific article published on 01 August 1999

PAMPA--a drug absorption in vitro model 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones.

scientific article published in March 2004

Population modelling to describe pharmacokinetics of amiodarone in rats: Relevance of plasma protein and tissue depot binding

scientific article published on 17 November 2006

Progress in the development of early diagnosis and a drug with unique pharmacology to improve cancer therapy

scientific article published on October 2008

Smart gated magnetic silica mesoporous particles for targeted colon drug delivery: New approaches for inflammatory bowel diseases treatment

scientific article published on 10 May 2018

Synthesis of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities

scientific article

The dopamine uptake inhibitor 3 alpha-[bis(4'-fluorophenyl)metoxy]-tropane reduces cocaine-induced early-gene expression, locomotor activity, and conditioned reward.

scientific article published on 15 July 2009

Therapeutic efficacy of quercetin enzyme-responsive nanovesicles for the treatment of experimental colitis in rats

scientific article published on 18 November 2014

Transdermal absorption of memantin--effect of chemical enhancers, iontophoresis, and role of enhancer lipophilicity

scientific article published on 23 June 2012

Transdermal drug delivery. Clinical aspects

scientific article published on 01 April 1998

Transdermal iontophoresis of dexamethasone sodium phosphate in vitro and in vivo: effect of experimental parameters and skin type on drug stability and transport kinetics

scientific article published on 21 March 2010

Transdermal nortriptyline hydrocloride patch formulated within a chitosan matrix intended to be used for smoking cessation

scientific article published on 09 February 2010

Transdermal therapeutic systems for memantine delivery. Comparison of passive and iontophoretic transport.

scientific article

Transdermal therapy and diagnosis by iontophoresis

scientific article published on August 1, 1997

Unique pharmacology of KAR-2, a potential anti-cancer agent: absorption modelling and selective mitotic spindle targeting.

scientific article

Using transdermal iontophoresis to increase granisetron delivery across skin in vitro and in vivo: effect of experimental conditions and a comparison with other enhancement strategies.

scientific article published on 21 January 2010

Validation of a biophysical drug absorption model by the PATQSAR system.

scientific article published in April 1999

Variability of permeability estimation from different protocols of subculture and transport experiments in cell monolayers.

scientific article published on 26 November 2014