List of works - Garry W Buchko

1H, 13C, and 15N resonance assignments of murine amelogenin, an enamel biomineralization protein.

scientific article published on June 2008

67Zn solid-state NMR spectroscopy of the minimal dna binding domain of human nucleotide excision repair protein XPA.

scientific article

A multi-pronged search for a common structural motif in the secretion signal of Salmonella enterica serovar Typhimurium type III effector proteins

scientific article published on 29 September 2010

A solution NMR investigation into the early events of amelogenin nanosphere self-assembly initiated with sodium chloride or calcium chloride

scientific journal article

A solution NMR investigation into the impaired self-assembly properties of two murine amelogenins containing the point mutations T21→I or P41→T

scientific journal article

Accurate de novo design of hyperstable constrained peptides

scientific article

Antifungal symbiotic peptide NCR044 exhibits unique structure and multifaceted mechanisms of action that confer plant protection

scientific article published on 22 June 2020

Backbone and side chain (1)H, (13)C, and (15)N NMR assignments for the organic hydroperoxide resistance protein (Ohr) from Burkholderia pseudomallei

scientific article published on 29 May 2009

Backbone chemical shift assignments and secondary structure analysis of the U1 protein from the Bas-Congo virus.

scientific article published on 15 December 2016

Backbone chemical shift assignments for Xanthomonas campestris peroxiredoxin Q in the reduced and oxidized states: a dramatic change in backbone dynamics.

scientific article published on 15 September 2015

Backbone chemical shift assignments for the sensor domain of the Burkholderia pseudomallei histidine kinase RisS: "missing" resonances at the dimer interface.

scientific article

Base excision repair: NMR backbone assignments of Escherichia coli formamidopyrimidine-DNA glycosylase.

scientific article

Characterization of gamma-radiation induced decomposition products of thymidine-containing dinucleoside monophosphates by nuclear magnetic resonance spectroscopy

scientific article published on 01 February 1993

Chemical shift assignments for Rv0577, a putative glyoxylase associated with virulence from Mycobacterium tuberculosis

scientific article

Chemical shift changes provide evidence for overlapping single-stranded DNA- and XPA-binding sites on the 70 kDa subunit of human replication protein A

scientific article

Circular dichroism studies on the Deinococcus radiodurans Nudix hydrolase DR_0079: an atypical thermal melt

scientific article published on 01 July 2010

Combining functional and structural genomics to sample the essential Burkholderia structome

scientific article

Compensating bends in a 16-base-pair DNA oligomer containing a T(3)A(3) segment: A NMR study of global DNA curvature.

scientific article

Conformation of two peptides corresponding to human apolipoprotein C-I residues 7-24 and 35-53 in the presence of sodium dodecyl sulfate by CD and NMR spectroscopy

scientific article

Constraint of DNA on functionalized graphene improves its biostability and specificity

scientific article published on 01 June 2010

Crystal structure of a macrophage migration inhibitory factor from Giardia lamblia

scientific article

Crystal structure of cce_0566 fromCyanothece 51142, a protein associated with nitrogen fixation in the DUF269 family

scientific article

Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide-rich de novo designed peptides

scientific article published on 01 September 2018

DNA-XPA interactions: a (31)P NMR and molecular modeling study of dCCAATAACC association with the minimal DNA-binding domain (M98-F219) of the nucleotide excision repair protein XPA.

scientific article published in June 2001

Enzyme design from the bottom up: an active nickel electrocatalyst with a structured peptide outer coordination sphere

scientific article published on 17 January 2014

Extended X-ray absorption fine structure evidence for a single metal binding domain in Xenopus laevis nucleotide excision repair protein XPA.

scientific article

Functional and Structural Characterization of DR_0079 from Deinococcus radiodurans , a Novel Nudix Hydrolase with a Preference for Cytosine (Deoxy)ribonucleoside 5′-Di- and Triphosphates †

scientific article

High-level expression, purification, crystallization and preliminary X-ray crystallographic studies of the receptor-binding domain of botulinum neurotoxin serotype D.

scientific article

High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity

scientific article published on 22 April 2021

Human nucleotide excision repair protein XPA: NMR spectroscopic studies of an XPA fragment containing the ERCC1-binding region and the minimal DNA-binding domain (M59-F219).

scientific article

Human nucleotide excision repair protein XPA: expression and NMR backbone assignments of the 14.7 kDa minimal damaged DNA binding domain (Met98-Phe219).

scientific article published on October 1997

Identification of major matrix metalloproteinase-20 proteolytic processing products of murine amelogenin and tyrosine-rich amelogenin peptide using a nuclear magnetic resonance spectroscopy based method

scientific article published on 06 June 2018

Identification of the alpha and beta anomers of 1-(2-deoxy-D-erythro-pentofuranosyl)-oxaluric acid at the site of riboflavin-mediated photooxidation of guanine in 2'-deoxyguanosine and thymidylyl-(3'-5')-2'-deoxyguanosine.

scientific article published in January 2006

Improved protocol to purify untagged amelogenin - Application to murine amelogenin containing the equivalent P70→T point mutation observed in human amelogenesis imperfecta

scientific article published on 13 October 2014

Inaugural structure from the DUF3349 superfamily of proteins, Mycobacterium tuberculosis Rv0543c ⬇️

scientific article published on December 6, 2010

Increasing the structural coverage of tuberculosis drug targets

scientific article

Influence of nitrogen, oxygen, and nitroimidazole radiosensitizers on DNA damage induced by ionizing radiation

scientific article published on 01 March 1993

Influence of nucleic acid base aromaticity on substrate reactivity with enzymes acting on single-stranded DNA.

scientific article

Infrared Spectroscopy of Human Apolipoprotein Fragments in SDS/D2O: Relative Lipid-Binding Affinities and a Novel Amide I Assignment ⬇️

scientific article published on November 25, 1997

Insights into the structural variation between pentapeptide repeat proteins--crystal structure of Rfr23 from Cyanothece 51142

scientific article

Investigating the role of chain and linker length on the catalytic activity of an H2 production catalyst containing a β-hairpin peptide

scientific article published on 02 June 2016

Isolation and characterization of a new product produced by ionizing irradiation and type I photosensitization of 2'-deoxyguanosine in oxygen-saturated aqueous solution: (2S)-2,5'-ANHYDRO-1-(2'-deoxy-beta-D-erythro-pentofuranosyl)-5-guanidin ylidene

scientific article published on June 1993

Methylene blue-mediated photooxidation of 7,8-dihydro-8-oxo-2'-deoxyguanosine.

scientific article published in July 1995

Mineral association changes the secondary structure and dynamics of murine amelogenin

scientific article

NMR resonance assignments of the human high mobility group protein HMGA1

scientific article published on 06 January 2007

Photooxidation of d(TpG) by riboflavin and methylene blue. Isolation and characterization of thymidylyl-(3',5')-2-amino-5-[(2-deoxy-beta-D- erythro-pentofuranosyl)amino]-4H-imidazol-4-one and its primary decomposition product thymidylyl-(3',5')-2,2-

scientific article published on October 1995

Recent contributions of structure-based drug design to the development of antibacterial compounds.

scientific article

Sequence-Defined Energetic Shifts Control the Disassembly Kinetics and Microstructure of Amelogenin Adsorbed onto Hydroxyapatite (100).

scientific article published on 18 September 2015

Solid-State NMR Identification of Intermolecular Interactions in Amelogenin Bound to Hydroxyapatite

scientific article published on 29 August 2018

Solution NMR structures of oxidized and reduced Ehrlichia chaffeensis thioredoxin: NMR-invisible structure owing to backbone dynamics

scientific article

Solution structure for an Encephalitozoon cuniculi adrenodoxin-like protein in the oxidized state

scientific article published on 20 January 2020

Solution structure of Rv2377c-founding member of the MbtH-like protein family

scientific article

Solution structure of an arsenate reductase-related protein, YffB, from Brucella melitensis , the etiological agent responsible for brucellosis

scientific article

Solution structure of the conserved hypothetical protein Rv2302 from Mycobacterium tuberculosis.

scientific article

Solution-state NMR investigation of DNA binding interactions in Escherichia coli formamidopyrimidine-DNA glycosylase (Fpg): a dynamic description of the DNA/protein interface.

scientific article published in March 2005

Solution-state NMR structure and biophysical characterization of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis

scientific article

Solution-state NMR structure of the putative morphogene protein BolA (PFE0790c) from Plasmodium falciparum

scientific article published on 18 April 2015

Structural analysis of the receptor binding domain of botulinum neurotoxin serotype D ⬇️

scientific article published on September 19, 2010

Structural and Biophysical Characterization of the Mycobacterium tuberculosis Protein Rv0577, a Protein Associated with Neutral Red Staining of Virulent Tuberculosis Strains and Homologue of the Streptomyces coelicolor Protein KbpA.

scientific article published on 10 July 2017

Structural and functional studies of a phosphatidic acid-binding antifungal plant defensin MtDef4: identification of an RGFRRR motif governing fungal cell entry

scientific article (publication date: 2013)

Structural characterization of Burkholderia pseudomallei adenylate kinase (Adk): Profound asymmetry in the crystal structure of the ‘open’ state

scientific article

Structural characterization of a soil viral auxiliary metabolic gene product – a functional chitosanase

scientific article published in 2022

Structural characterization of a β-hydroxyacid dehydrogenase from Geobacter sulfurreducens and Geobacter metallireducens with succinic semialdehyde reductase activity

scientific article

Structural diversity in the Mycobacteria DUF3349 superfamily

scientific article published on 21 November 2019

Structural features of the minimal DNA binding domain (M98-F219) of human nucleotide excision repair protein XPA.

scientific article

Structural genomics of infectious disease drug targets: the SSGCID.

scientific article

Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D

scientific article

Structural studies of a peptide activator of human lecithin-cholesterol acyltransferase.

scientific article published in February 1996

Structure Determination and Functional Analysis of a Chromate Reductase from Gluconacetobacter hansenii

scientific article

Structure of a CutA1 divalent-cation tolerance protein from Cryptosporidium parvum, the protozoal parasite responsible for cryptosporidiosis.

scientific article published on 18 April 2015

Structure of a Nudix hydrolase (MutT) in the Mg 2+ -bound state from Bartonella henselae , the bacterium responsible for cat scratch fever

scientific article

The Seattle Structural Genomics Center for Infectious Disease (SSGCID).

scientific article

The energetic basis for hydroxyapatite mineralization by amelogenin variants provides insights into the origin of amelogenesis imperfecta

scientific article published on 25 June 2019

The flexible structure of the K24S28 region of Leucine-Rich Amelogenin Protein (LRAP) bound to apatites as a function of surface type, calcium, mutation, and ionic strength.

scientific article

The leucine-rich amelogenin protein (LRAP) is primarily monomeric and unstructured in physiological solution.

scientific article

The use of sodium dodecyl sulfate to model the apolipoprotein environment. Evidence for peptide-SDS complexes using pulsed-field-gradient NMR spectroscopy

scientific article published on 01 May 1998

Using MbtH-Like Proteins to Alter the Substrate Profile of a Nonribosomal Peptide Adenylation Enzyme

scientific article published on 04 October 2018

[8] Singlet oxygen DNA damage: Chromatographic and mass spectrometric analysis of damage products

scientific article published in 1994

List of works by Garry W Buchko

1H, 13C, and 15N resonance assignments of murine amelogenin, an enamel biomineralization protein.

67Zn solid-state NMR spectroscopy of the minimal dna binding domain of human nucleotide excision repair protein XPA.

A multi-pronged search for a common structural motif in the secretion signal of Salmonella enterica serovar Typhimurium type III effector proteins

A solution NMR investigation into the early events of amelogenin nanosphere self-assembly initiated with sodium chloride or calcium chloride

A solution NMR investigation into the impaired self-assembly properties of two murine amelogenins containing the point mutations T21→I or P41→T

Accurate de novo design of hyperstable constrained peptides

Antifungal symbiotic peptide NCR044 exhibits unique structure and multifaceted mechanisms of action that confer plant protection

Backbone and side chain (1)H, (13)C, and (15)N NMR assignments for the organic hydroperoxide resistance protein (Ohr) from Burkholderia pseudomallei

Backbone chemical shift assignments and secondary structure analysis of the U1 protein from the Bas-Congo virus.

Backbone chemical shift assignments for Xanthomonas campestris peroxiredoxin Q in the reduced and oxidized states: a dramatic change in backbone dynamics.

Backbone chemical shift assignments for the sensor domain of the Burkholderia pseudomallei histidine kinase RisS: "missing" resonances at the dimer interface.

Base excision repair: NMR backbone assignments of Escherichia coli formamidopyrimidine-DNA glycosylase.

Characterization of gamma-radiation induced decomposition products of thymidine-containing dinucleoside monophosphates by nuclear magnetic resonance spectroscopy

Chemical shift assignments for Rv0577, a putative glyoxylase associated with virulence from Mycobacterium tuberculosis

Chemical shift changes provide evidence for overlapping single-stranded DNA- and XPA-binding sites on the 70 kDa subunit of human replication protein A

Circular dichroism studies on the Deinococcus radiodurans Nudix hydrolase DR_0079: an atypical thermal melt

Combining functional and structural genomics to sample the essential Burkholderia structome

Compensating bends in a 16-base-pair DNA oligomer containing a T(3)A(3) segment: A NMR study of global DNA curvature.

Conformation of two peptides corresponding to human apolipoprotein C-I residues 7-24 and 35-53 in the presence of sodium dodecyl sulfate by CD and NMR spectroscopy

Constraint of DNA on functionalized graphene improves its biostability and specificity

Crystal structure of a macrophage migration inhibitory factor from Giardia lamblia

Crystal structure of cce_0566 fromCyanothece 51142, a protein associated with nitrogen fixation in the DUF269 family

Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide-rich de novo designed peptides

DNA-XPA interactions: a (31)P NMR and molecular modeling study of dCCAATAACC association with the minimal DNA-binding domain (M98-F219) of the nucleotide excision repair protein XPA.

Enzyme design from the bottom up: an active nickel electrocatalyst with a structured peptide outer coordination sphere

Extended X-ray absorption fine structure evidence for a single metal binding domain in Xenopus laevis nucleotide excision repair protein XPA.

Functional and Structural Characterization of DR_0079 from Deinococcus radiodurans , a Novel Nudix Hydrolase with a Preference for Cytosine (Deoxy)ribonucleoside 5′-Di- and Triphosphates †

High-level expression, purification, crystallization and preliminary X-ray crystallographic studies of the receptor-binding domain of botulinum neurotoxin serotype D.

High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity

Human nucleotide excision repair protein XPA: NMR spectroscopic studies of an XPA fragment containing the ERCC1-binding region and the minimal DNA-binding domain (M59-F219).

Human nucleotide excision repair protein XPA: expression and NMR backbone assignments of the 14.7 kDa minimal damaged DNA binding domain (Met98-Phe219).

Identification of major matrix metalloproteinase-20 proteolytic processing products of murine amelogenin and tyrosine-rich amelogenin peptide using a nuclear magnetic resonance spectroscopy based method

Identification of the alpha and beta anomers of 1-(2-deoxy-D-erythro-pentofuranosyl)-oxaluric acid at the site of riboflavin-mediated photooxidation of guanine in 2'-deoxyguanosine and thymidylyl-(3'-5')-2'-deoxyguanosine.

Improved protocol to purify untagged amelogenin - Application to murine amelogenin containing the equivalent P70→T point mutation observed in human amelogenesis imperfecta

Inaugural structure from the DUF3349 superfamily of proteins, Mycobacterium tuberculosis Rv0543c ⬇️

Increasing the structural coverage of tuberculosis drug targets

Influence of nitrogen, oxygen, and nitroimidazole radiosensitizers on DNA damage induced by ionizing radiation

Influence of nucleic acid base aromaticity on substrate reactivity with enzymes acting on single-stranded DNA.

Infrared Spectroscopy of Human Apolipoprotein Fragments in SDS/D2O: Relative Lipid-Binding Affinities and a Novel Amide I Assignment ⬇️

Insights into the structural variation between pentapeptide repeat proteins--crystal structure of Rfr23 from Cyanothece 51142

Investigating the role of chain and linker length on the catalytic activity of an H2 production catalyst containing a β-hairpin peptide

Isolation and characterization of a new product produced by ionizing irradiation and type I photosensitization of 2'-deoxyguanosine in oxygen-saturated aqueous solution: (2S)-2,5'-ANHYDRO-1-(2'-deoxy-beta-D-erythro-pentofuranosyl)-5-guanidin ylidene

Methylene blue-mediated photooxidation of 7,8-dihydro-8-oxo-2'-deoxyguanosine.

Mineral association changes the secondary structure and dynamics of murine amelogenin

NMR resonance assignments of the human high mobility group protein HMGA1

Photooxidation of d(TpG) by riboflavin and methylene blue. Isolation and characterization of thymidylyl-(3',5')-2-amino-5-[(2-deoxy-beta-D- erythro-pentofuranosyl)amino]-4H-imidazol-4-one and its primary decomposition product thymidylyl-(3',5')-2,2-

Recent contributions of structure-based drug design to the development of antibacterial compounds.

Sequence-Defined Energetic Shifts Control the Disassembly Kinetics and Microstructure of Amelogenin Adsorbed onto Hydroxyapatite (100).

Solid-State NMR Identification of Intermolecular Interactions in Amelogenin Bound to Hydroxyapatite

Solution NMR structures of oxidized and reduced Ehrlichia chaffeensis thioredoxin: NMR-invisible structure owing to backbone dynamics

Solution structure for an Encephalitozoon cuniculi adrenodoxin-like protein in the oxidized state

Solution structure of Rv2377c-founding member of the MbtH-like protein family

Solution structure of an arsenate reductase-related protein, YffB, from Brucella melitensis , the etiological agent responsible for brucellosis

Solution structure of the conserved hypothetical protein Rv2302 from Mycobacterium tuberculosis.

Solution-state NMR investigation of DNA binding interactions in Escherichia coli formamidopyrimidine-DNA glycosylase (Fpg): a dynamic description of the DNA/protein interface.

Solution-state NMR structure and biophysical characterization of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis

Solution-state NMR structure of the putative morphogene protein BolA (PFE0790c) from Plasmodium falciparum

Structural analysis of the receptor binding domain of botulinum neurotoxin serotype D ⬇️

Structural and Biophysical Characterization of the Mycobacterium tuberculosis Protein Rv0577, a Protein Associated with Neutral Red Staining of Virulent Tuberculosis Strains and Homologue of the Streptomyces coelicolor Protein KbpA.

Structural and functional studies of a phosphatidic acid-binding antifungal plant defensin MtDef4: identification of an RGFRRR motif governing fungal cell entry

Structural characterization of Burkholderia pseudomallei adenylate kinase (Adk): Profound asymmetry in the crystal structure of the ‘open’ state

Structural characterization of a soil viral auxiliary metabolic gene product – a functional chitosanase

Structural characterization of a β-hydroxyacid dehydrogenase from Geobacter sulfurreducens and Geobacter metallireducens with succinic semialdehyde reductase activity

Structural diversity in the Mycobacteria DUF3349 superfamily

Structural features of the minimal DNA binding domain (M98-F219) of human nucleotide excision repair protein XPA.

Structural genomics of infectious disease drug targets: the SSGCID.

Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D

Structural studies of a peptide activator of human lecithin-cholesterol acyltransferase.

Structure Determination and Functional Analysis of a Chromate Reductase from Gluconacetobacter hansenii

Structure of a CutA1 divalent-cation tolerance protein from Cryptosporidium parvum, the protozoal parasite responsible for cryptosporidiosis.

Structure of a Nudix hydrolase (MutT) in the Mg 2+ -bound state from Bartonella henselae , the bacterium responsible for cat scratch fever

The Seattle Structural Genomics Center for Infectious Disease (SSGCID).

The energetic basis for hydroxyapatite mineralization by amelogenin variants provides insights into the origin of amelogenesis imperfecta

The flexible structure of the K24S28 region of Leucine-Rich Amelogenin Protein (LRAP) bound to apatites as a function of surface type, calcium, mutation, and ionic strength.

The leucine-rich amelogenin protein (LRAP) is primarily monomeric and unstructured in physiological solution.

The use of sodium dodecyl sulfate to model the apolipoprotein environment. Evidence for peptide-SDS complexes using pulsed-field-gradient NMR spectroscopy

Using MbtH-Like Proteins to Alter the Substrate Profile of a Nonribosomal Peptide Adenylation Enzyme

[8] Singlet oxygen DNA damage: Chromatographic and mass spectrometric analysis of damage products