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List of works by Patrick Dallemagne

26th Annual GP2A Medicinal Chemistry Conference & 32nd Journées Franco-Belges de Pharmacochimie

scientific article published on 16 May 2019

3-(Dipropylamino)-5-hydroxybenzofuro[2,3-f]quinazolin-1(2H)-one (DPA-HBFQ-1) plays an inhibitory role on breast cancer cell growth and progression.

scientific article published on 10 November 2015

6-Sulfonylbenzothiazolones as potential scaffolds for the design of 5-HT6 ligands

scientific article

Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerization

scientific article published on 02 August 2019

Benzylphenylpyrrolizinones with Anti-amyloid and Radical Scavenging Effects, Potentially Useful in Alzheimer's Disease Treatment.

scientific article published on 25 March 2017

Chronic activation of 5-HT4 receptors or blockade of 5-HT6 receptors improve memory performances

scientific article

Design and synthesis of a new type of non steroidal human aromatase inhibitors

scientific article published on 01 May 1998

Design, synthesis, and pharmacological evaluation of multitarget-directed ligands with both serotonergic subtype 4 receptor (5-HT4R) partial agonist and 5-HT6R antagonist activities, as potential treatment of Alzheimer's disease

scientific article published on 26 May 2016

Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium

scientific article published on 10 March 2015

Donecopride, a Swiss army knife with potential against Alzheimer's disease

scientific article published on 27 December 2019

Drug repositioning: a brief overview

scientific article published on 17 April 2020

First Synthesis of Racemic <i>Trans</i> Propargylamino-Donepezil, a Pleiotrope Agent Able to Both Inhibit AChE and MAO-B, with Potential Interest against Alzheimer's Disease

scientific article published on 27 December 2020

Hydrogenative desulphurization of thienopyrrolizinones: an easy and selective access to (Z)-phenethylidenepyrrolizinones with in vitro cytotoxic activity.

scientific article

Indenopyrazole oxime ethers: synthesis and β1-adrenergic blocking activity

scientific article

Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer's Disease

scientific article published on 31 July 2019

Intramolecular cyclisation of β-aryl-β-amino acids in the design of novel heterocyclic systems with therapeutic interest: an unfailing source of diversity.

scientific article published on January 2010

MR 20492 and MR 20494: two indolizinone derivatives that strongly inhibit human aromatase.

scientific article

Modulating 5-HT4 and 5-HT6 receptors in Alzheimer's disease treatment.

scientific article published on 15 May 2017

Multifaceted properties of 1,4-dimethylcarbazoles: Focus on trimethoxybenzamide and trimethoxyphenylurea derivatives as novel human topoisomerase II inhibitors

scientific article published in January 2017

N-substituted piperazinopyridylsteroid derivatives as abiraterone analogues inhibit growth and induce pro-apoptosis in human hormone-independent prostate cancer cell lines.

scientific article published in November 2013

New aromatase inhibitors. Synthesis and biological activity of aryl-substituted pyrrolizine and indolizine derivatives

scientific article published on 01 May 2000

Novel benzylidenephenylpyrrolizinones with pleiotropic activities potentially useful in Alzheimer's disease treatment.

scientific article

Novel multi target-directed ligands targeting 5-HT4 receptors with in cellulo antioxidant properties as promising leads in Alzheimer's disease

scientific article published on 06 August 2019

Novel multitarget-directed ligands (MTDLs) with acetylcholinesterase (AChE) inhibitory and serotonergic subtype 4 receptor (5-HT4R) agonist activities as potential agents against Alzheimer's disease: the design of donecopride

scientific article published on 31 March 2015

Pharmacotechnical Development of a Nasal Drug Delivery Composite Nanosystem Intended for Alzheimer's Disease Treatment

scientific article published on 11 March 2020

Recent Advances in Phenanthroindolizidine and Phenanthroquinolizidine Derivatives with Anticancer Activities

scientific article published on 20 May 2015

Replication of Equine arteritis virus is efficiently suppressed by purine and pyrimidine biosynthesis inhibitors

scientific article published on 10 April 2020

Screening and evaluation of antiviral compounds against Equid alpha-herpesviruses using an impedance-based cellular assay

scientific article published on 26 October 2018

Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT(4) receptor activation (RS67333) on object recognition in mice.

scientific article

Synthesis and Evaluation of the CNS Activity of New 4-Alkoxyphenylimidazolidin-2-ones

scientific article published on April 1, 1998

Synthesis and biological evaluation as AChE inhibitors of new indanones and thiaindanones related to donepezil.

scientific article published on 30 August 2005

Synthesis and biological evaluation of cyclopenta[c]thiophene related compounds as new antitumor agents.

scientific article

Synthesis and biological evaluation of five-membered heterocycles fused to cyclopenta[c]thiophene as new antitumor agents.

scientific article published on April 2003

Synthesis and biological evaluation of new donepezil-like Thiaindanones as AChE inhibitors

scientific article published on 01 October 2008

Synthesis and biological evaluation of novel pyrrolopyrrolizinones as anticancer agents

scientific article published on 29 September 2006

Synthesis and biological evaluation of thienopyrrolizines, a new family of CDK/GSK-3 inhibitors.

scientific article published in December 2004

Synthesis and cytotoxic activity against L1210 leukemia of new aminocyclopenta[c]thiophenones

scientific article published on 01 August 1994

Synthesis and evaluation of cytotoxic activities of new guanidines derived from carbazoles.

scientific article

Synthesis and evaluation of novel serotonin 4 receptor radiotracers for single photon emission computed tomography.

scientific article published on 25 March 2016

Synthesis and in vitro evaluation of 4-trichloromethylpyrrolo[1,2-a]quinoxalines as new antiplasmodial agents.

scientific article published on 10 June 2014

Synthesis and preliminary behavioural evaluation in mice of new 3-aryl-3-pyrrol-1-ylpropanamides, analogues of FGIN-1-27 and FGIN-1-43.

scientific article

Synthesis and preliminary in vivo evaluation of new 2-Aryl-6-methyl-1,2-dihydro-1H-pyridin-4-ones and 2-Aryl-6-methylpiperidin-4-ols, as potential anti-amnesiant agents.

scientific article published in December 2005

Synthesis of new bisaryl cyclopentathiophene and thienocyclopentoxazolidine derivatives as potential cytotoxic agents.

scientific article published on October 2007

Synthesis of new dipyrrolo- and furopyrrolopyrazinones related to tripentones and their biological evaluation as potential kinases (CDKs1-5, GSK-3) inhibitors

scientific article published on 23 May 2008

Synthesis of novel 7-oxo and 7-hydroxy trifluoroallocolchicinoids with cytotoxic effect

scientific article published on 03 March 2012

The 52nd International Conference on Medicinal Chemistry (RICT 2016) of the French Medicinal Chemistry Society (SCT) Held in Caen (Normandy).

scientific article published in June 2017

Therapeutic Potential of 5-HT6 Receptor Agonists.

scientific article published on 22 June 2015

Two Antagonistic Microtubule Targeting Drugs Act Synergistically to Kill Cancer Cells

scientific article published on 06 August 2020

Virtual screening discovery of new acetylcholinesterase inhibitors issued from CERMN chemical library

scientific article