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List of works by Huihao Zhou

ASDB: a resource for probing protein functions with small molecules.

scientific article published on 28 January 2016

ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase

scientific article

Corrigendum: CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase

scientific article published on 20 January 2016

Crystal structure of a membrane-bound l-amino acid deaminase from Proteus vulgaris

scientific article

Crystallization and preliminary crystallographic analysis of tRNA (m(7)G46) methyltransferase from Escherichia coli

scientific article published on 31 July 2008

DeepChemStable: Chemical Stability Prediction with an Attention-Based Graph Convolution Network

scientific article published on 21 February 2019

Design, syntheses and lipid accumulation inhibitory activities of novel resveratrol mimics.

scientific article published on 7 November 2017

Design, synthesis, and biological evaluation of compounds with a new scaffold as anti-neuroinflammatory agents for the treatment of Alzheimer's disease

scientific article published on 27 February 2018

Discovery of a New Pterocarpan-Type Antineuroinflammatory Compound from Sophora tonkinensis through Suppression of the TLR4/NFκB/MAPK Signaling Pathway with PU.1 as a Potential Target

scientific article published on 28 September 2018

Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid.

scientific article published on 22 December 2017

Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4:U69 Base Pair

scientific article

Identification of an auxiliary druggable pocket in the DNA gyrase ATPase domain using fragment probes

scientific article published on 04 July 2018

Identify liver X receptor β modulator building blocks by developing a fluorescence polarization-based competition assay

scientific article published on 10 June 2019

Membrane binding of the insertion sequence of Proteus vulgaris L-amino acid deaminase stabilizes protein structure and increases catalytic activity

scientific article published on 20 October 2017

OSBP-Related Protein 5L Maintains Intracellular IP3/Ca2+ Signaling and Proliferation in T Cells by Facilitating PIP2 Hydrolysis

scientific article published on 17 January 2020

PTS: a pharmaceutical target seeker.

scientific article published on 28 December 2017

RNA function. Ribosome stalling induced by mutation of a CNS-specific tRNA causes neurodegeneration.

scientific article

Structural Insights into Substrate Recognition and Activity Regulation of the Key Decarboxylase SbnH in Staphyloferrin B Biosynthesis

scientific article published on 18 October 2019

Structural Insights into the Down-regulation of Overexpressed p185 Protein of Transformed Cells by the Antibody chA21

scientific article published on June 16, 2011

Structurally Selective Mechanism of Liver X Receptor Ligand: In Silico and In Vitro Studies

scientific article published on 26 June 2019

Structure-guided optimization and mechanistic study of a class of quinazolinone-threonine hybrids as antibacterial ThrRS inhibitors

scientific article published on 19 September 2020

Synthesis and evaluation of tetrahydroisoquinoline-benzimidazole hybrids as multifunctional agents for the treatment of Alzheimer's disease

scientific article published on 04 February 2019

Systematic Studies on the Protocol and Criteria for Selecting a Covalent Docking Tool

scientific article published on 10 June 2019

The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs

scientific article

X-shaped structure of bacterial heterotetrameric tRNA synthetase suggests cryptic prokaryote functions and a rationale for synthetase classifications

scientific article published on 01 September 2021

cBinderDB: a covalent binding agent database

scientific article published on 23 December 2016