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List of works by Eileen J Kennedy

A Stapled Peptide Mimic of the Pseudosubstrate Inhibitor PKI Inhibits Protein Kinase A

scientific article published on 20 April 2019

AKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA.

scientific article

Cell penetrating peptides to dissect host-pathogen protein-protein interactions in Theileria-transformed leukocytes

scientific article published on 7 September 2017

Conformationally constrained peptides target the allosteric kinase dimer interface and inhibit EGFR activation.

scientific article published on 5 September 2017

Constrained peptides and biological targets

scientific article published in March 2018

Contribution of Non-catalytic Core Residues to Activity and Regulation in Protein Kinase A

scientific article published on 6 March 2009

Correction to Isoform-Selective Disruption of AKAP-Localized PKA Using Hydrocarbon Stapled Peptides.

scientific article

Correction: Hydrophobic Core Variations Provide a Structural Framework for Tyrosine Kinase Evolution and Functional Specialization

scientific article published on 11 August 2016

Defining A-Kinase Anchoring Protein (AKAP) Specificity for the Protein Kinase A Subunit RI (PKA-RI)

scientific article published on 27 November 2015

Design of a selenylsulfide-bridged EGFR dimerization arm mimic

scientific article published on 20 March 2015

Development of rabbit monoclonal antibodies for detection of alpha-dystroglycan in normal and dystrophic tissue

scientific article

Dialing in EGFR Signaling.

scientific article published in June 2015

EMBO conference series: Chemical Biology 2014

scientific article published on 16 October 2014

Genetically encoded biosensors for visualizing live-cell biochemical activity at super-resolution

scientific article published on 13 March 2017

HK2 Recruitment to Phospho-BAD Prevents Its Degradation, Promoting Warburg Glycolysis by Theileria-Transformed Leukocytes

scientific article published on 13 January 2017

Hydrophobic Core Variations Provide a Structural Framework for Tyrosine Kinase Evolution and Functional Specialization

scientific article published in February 2016

Identification of functionally distinct regions that mediate biological activity of the protein kinase a homolog Tpk2.

scientific article published on 30 October 2007

Identifying critical non-catalytic residues that modulate protein kinase A activity

scientific article published in 2009

Inhibiting EGFR dimerization using triazolyl-bridged dimerization arm mimics

scientific article

Investigating PKA-RII specificity using analogs of the PKA:AKAP peptide inhibitor STAD-2.

scientific article published on 12 February 2018

Isoform-selective disruption of AKAP-localized PKA using hydrocarbon stapled peptides

scientific article published on 21 January 2014

Kynurenine, a Tryptophan Metabolite That Accumulates With Age, Induces Bone Loss

scientific article published on 20 July 2017

Lysophosphatidic Acid Mediates Activating Transcription Factor 3 Expression Which Is a Target for Post-Transcriptional Silencing by miR-30c-2-3p

scientific article published on 29 September 2015

Mitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic α-helix ⬇️

scientific article published on 6 March 2018

Molecular Modeling and Functional Analysis of Exome Sequencing-Derived Variants of Unknown Significance Identify a Novel, Constitutively Active FGFR2 Mutant in Cholangiocarcinoma

scientific article published in 2017

Neurochondrin is an atypical RIIα-specific A-kinase anchoring protein

scientific article published on 23 April 2015

Oxidation of the aromatic amino acids tryptophan and tyrosine disrupts their anabolic effects on bone marrow mesenchymal stem cells

scientific article published on 28 January 2015

PKA and Apicomplexan Parasite Diseases

scientific article published on 22 November 2016

PKA and Apicomplexan Parasite Diseases.

scientific article published on 11 November 2016

PKA-type I selective constrained peptide disruptors of AKAP complexes

scientific article published on 25 March 2015

Persistent Electrical Activity in Primary Nociceptors after Spinal Cord Injury Is Maintained by Scaffolded Adenylyl Cyclase and Protein Kinase A and Is Associated with Altered Adenylyl Cyclase Regulation

scientific article published on February 2016

Pho5p and newly identified nucleotide pyrophosphatases/ phosphodiesterases regulate extracellular nucleotide phosphate metabolism in Saccharomyces cerevisiae

scientific article published in November 2005

Protein kinase A-mediated phosphorylation of naked cuticle homolog 2 stimulates cell-surface delivery of transforming growth factor-α for epidermal growth factor receptor transactivation

scientific article published on 01 May 2019

Selective disruption of the AKAP signaling complexes

scientific article published on January 2015

Structural and evolutionary divergence of cyclic nucleotide binding domains in eukaryotic pathogens: Implications for drug design

scientific article published on 3 April 2015

Suppression of Breast Cancer Metastasis Using Stapled Peptides Targeting the WASF Regulatory Complex

scientific article published on 19 June 2017

Targeted Inhibition of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 with a Constrained J Domain-Derived Disruptor Peptide

scientific article published on 18 February 2019

Targeting Plasmodium with constrained peptides and peptidomimetics

scientific article published on 10 February 2020

Targeting kinase signaling pathways with constrained peptide scaffolds

scientific article published on 7 February 2017

Targeting the WASF3-CYFIP1 Complex Using Stapled Peptides Suppresses Cancer Cell Invasion

scientific article published on 16 December 2015

The Stapled AKAP Disruptor Peptide STAD-2 Displays Antimalarial Activity through a PKA-Independent Mechanism

scientific article

The WASF3-NCKAP1-CYFIP1 Complex Is Essential for Breast Cancer Metastasis

scientific article published on 18 July 2016

mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif

scientific article published on 13 April 2021

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