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List of works by Edward T Morgan

A non-lethal malarial infection results in reduced drug metabolizing enzyme expression and drug clearance in mice

scientific article published on 12 July 2019

A role for one or more p450 enzymes in the response to sepsis.

scientific article published in January 2005

Alcohol oxidation by isozyme 3a of liver microsomal cytochrome P-450

scientific article published on 01 January 1983

Altered inflammatory responses to Citrobacter rodentium infection, but not bacterial lipopolysaccharide, in mice lacking the Cyp4a10 or Cyp4a14 genes

scientific article

Cancer, inflammation, and therapy: effects on cytochrome p450-mediated drug metabolism and implications for novel immunotherapeutic agents.

scientific article published on 02 July 2014

Catalytic activity of cytochrome P-450 isozyme 3a isolated from liver microsomes of ethanol-treated rabbits. Oxidation of alcohols

scientific article published on 01 December 1982

Changes in the rat hepatic mixed function oxidase system associated with chronic ethanol vapor inhalation

scientific article published on 01 March 1981

Characterization of CYP4A induction in rat liver by inflammatory stimuli: dependence on sex, strain, and inflammation-evoked hypophagia.

scientific article

Comparison of six rabbit liver cytochrome P-450 isozymes in formation of a reactive metabolite of acetaminophen

scientific article published on 01 April 1983

Cytochromes P450 and flavin monooxygenases--targets and sources of nitric oxide.

scientific article

Differences in glycogen, lipids, and enzymes in livers from rats flown on COSMOS 2044

scientific article published on 01 August 1992

Differential inductive and suppressive effects of endotoxin and particulate irritants on hepatic and renal cytochrome P-450 expression

scientific article published on 01 March 1997

Down-Regulation of Cytochrome P450 mRNAs and Proteins in Mice Lacking a Functional NOS2 Gene ⬇️

scientific article published on August 1, 1998

Down-regulation of multiple cytochrome P450 gene products by inflammatory mediators in vivo. Independence from the hypothalamo-pituitary axis

scientific journal article

Down-regulation of phenobarbital-induced cytochrome P4502B mRNAs and proteins by endotoxin in mice: independence from nitric oxide production by inducible nitric oxide synthase

scientific article published on 01 December 2002

Down-regulation of the expression of three major rat liver cytochrome P450S by endotoxin in vivo occurs independently of nitric oxide production

scientific article published on 01 October 1998

Dual mechanisms of CYP3A protein regulation by proinflammatory cytokine stimulation in primary hepatocyte cultures.

scientific article published on 26 January 2009

Effects of bacterial lipopolysaccharide on phenobarbital-induced CYP2B expression in mice

scientific article published on 01 March 2001

Effects of cytochrome b5 on cytochrome P-450-catalyzed reactions. Studies with manganese-substituted cytochrome b5

scientific article published on 01 May 1984

Effects of early maternal separation on ethanol intake, GABA receptors and metabolizing enzymes in adult rats.

scientific article published in August 2005

Effects of vanadate on hepatic cytochrome P-450 expression in streptozotocin-diabetic rats.

scientific article published in July 1990

Endotoxemia in rats is associated with induction of the P4504A subfamily and suppression of several other forms of cytochrome P450.

scientific article

Expression of UDP-glucuronosyltransferase isoform mRNAs during inflammation and infection in mouse liver and kidney

scientific article

Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes.

scientific article

Growth hormone regulates expression of rat liver cytochrome P-450 15 beta at a pretranslational level

scientific article published on 01 March 1987

Growth hormone-dependent and -independent regulation of cytochrome P-450 isozyme expression in streptozotocin-diabetic rats

scientific article published on 01 April 1991

Hepatic and renal cytochrome p450 gene regulation during citrobacter rodentium infection in wild-type and toll-like receptor 4 mutant mice.

scientific article

Hepatic cytochrome P450 regulation in disease states

scientific article

Hepatic cytochrome P450s, phase II enzymes and nuclear receptors are downregulated in a Th2 environment during Schistosoma mansoni infection.

scientific article published on 25 October 2013

Hepatic flavin-containing monooxygenase gene regulation in different mouse inflammation models.

scientific article published on 16 December 2008

Hormonal and developmental regulation of expression of the hepatic microsomal steroid 16 alpha-hydroxylase cytochrome P-450 apoprotein in the rat

scientific article published on 01 October 1985

Impact of infectious and inflammatory disease on cytochrome P450-mediated drug metabolism and pharmacokinetics ⬇️

scientific article

Inflammatory prompts produce isoform-specific changes in the expression of leukotriene B(4) omega-hydroxylases in rat liver and kidney.

scientific article

Inhibition of estrogen-induced mammary tumor formation in MMTV-aromatase transgenic mice by 4-chlorophenylacetate.

scientific article published on 9 January 2007

Mechanisms of cytochrome P450 regulation by inflammatory mediators.

scientific article

Metabolism and action of proteasome inhibitors in primary human hepatocytes

scientific article

Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis

scientific article published on February 2008

Modulation of cytochrome P-450 gene expression in endotoxemic mice is tissue specific and peroxisome proliferator-activated receptor-alpha dependent

scientific article published on 01 September 1999

Modulation of drug metabolism in infectious and inflammatory diseases

scientific article

Molecular cloning and regulation of expression of two novel mouse CYP4F genes: expression in peroxisome proliferator-activated receptor alpha-deficient mice upon lipopolysaccharide and clofibrate challenges

scientific article

Nitric Oxide Mediated Degradation of CYP2A6 via the Ubiquitin-Proteasome Pathway in Human Hepatoma Cells

scientific article published on 29 April 2020

Nitric oxide and interleukin-1β stimulate the proteasome-independent degradation of the retinoic acid hydroxylase CYP2C22 in primary rat hepatocytes.

scientific article published on 21 October 2013

Nitric oxide-dependent CYP2B degradation is potentiated by a cytokine-regulated pathway and utilizes the immunoproteasome subunit LMP2

scientific journal article

Nitric oxide-dependent proteasomal degradation of cytochrome P450 2B proteins

scientific article

Nitric oxide-independent suppression of P450 2C11 expression by interleukin-1beta and endotoxin in primary rat hepatocytes

scientific article published on 01 September 1997

Oxidation of tricyclic antidepressant drugs, debrisoquine and 7-ethoxyresorufin, by human liver preparations

scientific article published on 01 May 1986

Physiological Regulation of Drug Metabolism and Transport: Pregnancy, Microbiome, Inflammation, Infection, and Fasting

scientific article published on 7 March 2018

Physiological and pathophysiological regulation of cytochrome P450.

scientific article published in December 1998

Preparation and characterization of monoclonal antibodies recognizing unique epitopes on sexually differentiated rat liver cytochrome P-450 isozymes

scientific article published in July 1987

Pretranslational induction of CYP4A subfamily gene products in diabetic rats and reversal by oral vanadate treatment

scientific article published on 01 July 1993

Pretranslational suppression of cytochrome P-450h (IIC11) gene expression in rat liver after administration of interferon inducers

scientific article published on 01 September 1990

Purification and characterization of a unique isozyme of cytochrome P-450 from liver microsomes of ethanol-treated rabbits

scientific article published on 01 July 1982

Purification of a desmethylimipramine and debrisoquine hydroxylating cytochrome P-450 from human liver

scientific article published on 01 September 1986

Purification, characterization, and pituitary regulation of the sex-specific cytochrome P-450 15 beta-hydroxylase from liver microsomes of untreated female rats.

scientific article published in December 1984

Rapid transcriptional suppression of rat cytochrome P450 genes by endotoxin treatment and its inhibition by curcumin.

scientific article published on 13 October 2003

Regulation of cytochrome P450 2C11 (CYP2C11) gene expression by interleukin-1, sphingomyelin hydrolysis, and ceramides in rat hepatocytes

scientific article published on 01 October 1995

Regulation of cytochrome P450 enzyme activity and expression by nitric oxide in the context of inflammatory disease

scientific article published on 08 September 2020

Regulation of cytochrome P450 expression by sphingolipids.

scientific article

Regulation of cytochrome p450 by inflammatory mediators: why and how?

scientific article

Regulation of cytochromes P450 during inflammation and infection.

scientific article published on November 1997

Regulation of drug-metabolizing enzymes and transporters in infection, inflammation, and cancer

scientific article published on 01 February 2008

Regulation of hepatic cytochrome P450 2C11 by glucocorticoids

scientific article published on 01 September 1997

Regulation of hepatic cytochrome P450 2C11 by transforming growth factor-beta, hepatocyte growth factor, and interleukin-11

scientific article published on 01 October 1998

Roles of nitric oxide in inflammatory downregulation of human cytochromes P450.

scientific article published on 23 December 2007

Selective Modulation of Hepatic Cytochrome P450 and Flavin Monooxygenase 3 Expression duringCitrobacter rodentiumInfection in Severe Combined Immune-Deficient Mice ⬇️

scientific article published on June 27, 2012

Selective and cytokine-dependent regulation of hepatic transporters and bile acid homeostasis during infectious colitis in mice

scientific article published on 30 December 2013

Selective role for tumor necrosis factor-α, but not interleukin-1 or Kupffer cells, in down-regulation of CYP3A11 and CYP3A25 in livers of mice infected with a noninvasive intestinal pathogen

scientific article

Selective suppression of cytochrome P-450 gene expression by interleukins 1 and 6 in rat liver

scientific article published on 01 October 1994

Selective suppression of rat hepatic cytochrome P450 2C11 by chloramphenicol

scientific article published on 01 September 1994

Sexual differentiation of cytochrome P-450 in rat liver. Evidence for a constitutive isozyme as the male-specific 16 alpha-hydroxylase.

scientific article published on April 1985

Sphingolipid-dependent signaling in regulation of cytochrome P450 expression

scientific article published on 01 January 1996

Sphingomyelin hydrolysis and regulation of the expression of the gene for cytochrome P450.

scientific article

Suppression of constitutive cytochrome P-450 gene expression in livers of rats undergoing an acute phase response to endotoxin

scientific article published on 01 November 1989

Suppression of constitutive cytochrome P450 gene expression by epidermal growth factor receptor ligands in cultured rat hepatocytes

scientific article published on 01 May 1996

Suppression of rat hepatic microsomal cytochromes P450 by cyclophosphamide is correlated with plasma thyroid hormone levels and displays differential strain sensitivity.

scientific article published in January 1996

Suppression of the constitutive expression of cytochrome P-450 2C11 by cytokines and interferons in primary cultures of rat hepatocytes: comparison with induction of acute-phase genes and demonstration that CYP2C11 promoter sequences are involved in

scientific article published on 01 May 1995

TLR4-dependent and -independent regulation of hepatic cytochrome P450 in mice with chemically induced inflammatory bowel disease

scientific article

The dose-response model for dioxin

scientific article published on 01 February 1998

The effect of adrenalectomy upon the absorption, distribution and metabolism of ethanol in the rat

scientific article published on October 1, 1977

The field of pharmacology and toxicology

scientific article published on 01 March 2012

The receptor tyrosine kinase EphB2 promotes hepatic fibrosis in mice

scientific article

Transcriptional suppression of cytochrome P450 genes by endogenous and exogenous chemicals.

scientific article published on April 2004

Tyrosine Nitration Contributes to Nitric Oxide-Stimulated Degradation of CYP2B6

scientific article published on 01 September 2020

Tyrosine nitration contributes to nitric oxide-stimulated degradation of CYP2B6

scientific article published on 03 July 2020

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