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List of works by Michele Tonelli

3-(4-Chloro-phenyl-diazen-yl)-1-methyl-1,4,5,6-tetra-hydro-pyridine.

scientific article published on 19 June 2008

9-Aminoacridine-based agents impair the bovine viral diarrhea virus (BVDV) replication targeting the RNA-dependent RNA polymerase (RdRp).

scientific article published on 4 January 2018

A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists

Acridine derivatives as anti-BVDV agents.

scientific article published on 14 May 2011

Antimicrobial and cytotoxic arylazoenamines. Part III: antiviral activity of selected classes of arylazoenamines.

scientific article published on 15 August 2008

Antitubercular activity of quinolizidinyl/pyrrolizidinylalkyliminophenazines.

scientific article

Antiviral activity of benzimidazole derivatives. I. Antiviral activity of 1-substituted-2-[(benzotriazol-1/2-yl)methyl]benzimidazoles.

scientific article published on November 2008

Antiviral activity of benzimidazole derivatives. II. Antiviral activity of 2-phenylbenzimidazole derivatives

scientific article

Antiviral activity of benzimidazole derivatives. III. Novel anti-CVB-5, anti-RSV and anti-Sb-1 agents

scientific article

Antiviral activity of benzotriazole derivatives. 5-[4-(Benzotriazol-2-yl)phenoxy]-2,2-dimethylpentanoic acids potently and selectively inhibit Coxsackie Virus B5.

scientific article published on 25 September 2015

Antiviral and cytotoxic activities of aminoarylazo compounds and aryltriazene derivatives.

scientific article published on 15 May 2009

Benzimidazole derivatives endowed with potent antileishmanial activity.

scientific article published in December 2018

Benzimidazole-based derivatives as privileged scaffold developed for the treatment of the RSV infection: a computational study exploring the potency and cytotoxicity profiles.

scientific article published on December 2017

Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells

scientific article published on 18 November 2014

Clofazimine analogs with antileishmanial and antiplasmodial activity.

scientific article

Efficacy of novel acridine derivatives in the inhibition of hPrP90-231 prion protein fragment toxicity

scientific article

Exhaustive CoMFA and CoMSIA analyses around different chemical entities: a ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands

scientific article published in December 2017

Exploring the effectiveness of novel benzimidazoles as CB2 ligands: synthesis, biological evaluation, molecular docking studies and ADMET prediction

scientific article published on 10 October 2018

Fight Against H1N1 Influenza A Virus: Recent Insights Towards the Development of Druggable Compounds.

scientific article published on 10 February 2016

Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus

scientific article published on 27 April 2017

Inhibition of Chloride Intracellular Channel 1 (CLIC1) as Biguanide Class-Effect to Impair Human Glioblastoma Stem Cell Viability

scientific article published on 21 August 2018

Molecular Docking and QSAR Studies as Computational Tools Exploring the Rescue Ability of F508del CFTR Correctors

scientific article published on 29 October 2020

Multitarget Therapeutic Leads for Alzheimer's Disease: Quinolizidinyl Derivatives of Bi- and Tricyclic Systems as Dual Inhibitors of Cholinesterases and β-Amyloid (Aβ) Aggregation

scientific article published on 29 April 2015

New Insights into the Binding Features of F508del CFTR Potentiators: A Molecular Docking, Pharmacophore Mapping and QSAR Analysis Approach

scientific article published on 04 December 2020

New arylsparteine derivatives as positive inotropic drugs.

scientific article

New insights into the structure of the trace amine-associated receptor 2: Homology modelling studies exploring the binding mode of 3-iodothyronamine

scientific article

Novel 1-Amidino-4-Phenylpiperazines as Potent Agonists at Human TAAR1 Receptor: Rational Design, Synthesis, Biological Evaluation and Molecular Docking Studies

scientific article published on 14 November 2020

Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies

scientific article

Novel celecoxib analogues inhibit glial production of prostaglandin E2, nitric oxide, and oxygen radicals reverting the neuroinflammatory responses induced by misfolded prion protein fragment 90-231 or lipopolysaccharide.

scientific article published on 22 September 2016

Novel quinolizidinyl derivatives as antiarrhythmic agents: 2. Further investigation

scientific article published in June 2010

Pharmacophore modeling, resistant mutant isolation, docking, and MM-PBSA analysis: Combined experimental/computer-assisted approaches to identify new inhibitors of the bovine viral diarrhea virus (BVDV).

scientific article published on 29 January 2010

Pyrazole and imidazo[1,2-b]pyrazole Derivatives as New Potential Antituberculosis Agents

scientific article published on 01 January 2019

Quinolizidine-Derived Lucanthone and Amitriptyline Analogues Endowed with Potent Antileishmanial Activity

scientific article published on 25 October 2020

Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer’s disease

scientific article published on 05 March 2011

Quinolizidinyl-benzimidazoles as platelet-antiaggregating agents.

scientific article published in May 2008

Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists.

scientific article

Synergistic experimental/computational studies on arylazoenamine derivatives that target the bovine viral diarrhea virus RNA-dependent RNA polymerase.

scientific article published on 25 June 2010

Synthesis and Antiplasmodial Activity of Novel Chloroquine Analogues with Bulky Basic Side Chains

scientific article published on 24 July 2015

Synthesis and Biological Evaluation of Novel (thio)semicarbazone-Based Benzimidazoles as Antiviral Agents against Human Respiratory Viruses

scientific article published on 25 March 2020

Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR)

scientific article published on 02 June 2018

Targeting species-specific trace amine-associated receptor 1 ligands: to date perspective of the rational drug design process.

scientific article

Trace amine associated receptor 1 (TAAR1) modulators: a patent review (2010-present)

scientific article published on 25 December 2019

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