List of works - Hai-Xue Pan

A Six-Oxidase Cascade for Tandem C-H Bond Activation Revealed by Reconstitution of Bicyclomycin Biosynthesis

scientific article

Activation and Characterization of Cryptic Gene Cluster: Two Series of Aromatic Polyketides Biosynthesized by Divergent Pathways

scientific article published on 24 October 2019

Analysis of YM-216391 biosynthetic gene cluster and improvement of the cyclopeptide production in a heterologous host.

scientific article published on 31 January 2012

Biosynthesis of trioxacarcin revealing a different starter unit and complex tailoring steps for type II polyketide synthase.

scientific article published on 7 April 2015

Characterization of Miharamycin Biosynthesis Reveals a Hybrid NRPS-PKS to Synthesize High-Carbon Sugar from a Complex Nucleoside

scientific article published on 17 March 2020

Characterization of QmnD3/QmnD4 for double bond formation in quartromicin biosynthesis

scientific article published on 28 February 2014

Directed production of aurantizolicin and new members based on a YM-216391 biosynthetic system

scientific article published on 01 December 2018

Elucidation of the Herbicidin Tailoring Pathway Offers Insights into Its Structural Diversity

scientific article published on 14 February 2019

Enzymatic Formation of Oxygen-Containing Heterocycles in Natural Product Biosynthesis

scientific article published on 21 August 2018

Enzymology of Anthraquinone-γ-Pyrone Ring Formation in Complex Aromatic Polyketide Biosynthesis

scientific article published on 19 September 2018

Genetic manipulation revealing an unusual N-terminal region in a stand-alone non-ribosomal peptide synthetase involved in the biosynthesis of ramoplanins ⬇️

scientific article published on September 25, 2012

Identification of phoslactomycin biosynthetic gene clusters from Streptomyces platensis SAM-0654 and characterization of PnR1 and PnR2 as positive transcriptional regulators.

scientific article published on 25 August 2012

Identification of the Amipurimycin Gene Cluster Yields Insight into the Biosynthesis of C9 Sugar Nucleoside Antibiotics

scientific article published on 16 April 2019

New insights into bacterial type II polyketide biosynthesis.

scientific article published on 21 February 2017

Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework

scientific article published on October 2009

Production of a trioxacarcin analog by introducing a C-3 dehydratase into deoxysugar biosynthesis

scientific article published on 01 May 2019

Production of doramectin by rational engineering of the avermectin biosynthetic pathway ⬇️

scientific article published on April 9, 2011

Production of ramoplanin analogues by genetic engineering of Actinoplanes sp.

scientific article published on 26 June 2013

Quartromicin Biosynthesis: Two Alternative Polyketide Chains Produced by One Polyketide Synthase Assembly Line ⬇️

scientific article published on October 26, 2012

The Miharamycins and Amipurimycin: their Structural Revision and the Total Synthesis of the Latter

scientific article published on 01 July 2019

The SARP Family Regulator Txn9 and Two-Component Response Regulator Txn11 are Key Activators for Trioxacarcin Biosynthesis in Streptomyces bottropensis

scientific article published on 16 July 2015

Thiopeptide biosynthesis featuring ribosomally synthesized precursor peptides and conserved posttranslational modifications