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List of works by Michele Signore

A new bioavailable fenretinide formulation with antiproliferative, antimetabolic, and cytotoxic effects on solid tumors

scientific article published on 23 July 2019

A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds

scientific article published on 10 November 2015

Activity of the BH3 mimetic ABT-737 on polycythemia vera erythroid precursor cells.

scientific article

Altered Traffic of Cardiolipin during Apoptosis: Exposure on the Cell Surface as a Trigger for "Antiphospholipid Antibodies"

scientific article

Antibody Validation by Western Blotting.

scientific article

Antibody validation by Western blotting.

scientific article

Approaching the increasing complexity of non-small cell lung cancer taxonomy

scientific article published on January 2014

C-Met/miR-130b axis as novel mechanism and biomarker for castration resistance state acquisition.

scientific article published on 13 February 2017

CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells

scientific article

Cancer Stem Cell-Based Models of Colorectal Cancer Reveal Molecular Determinants of Therapy Resistance.

scientific article

Cancer quasispecies and stem-like adaptive aneuploidy

scientific article published on 06 December 2013

Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme.

scientific article

Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1.

scientific article published on 29 October 2015

Chemotherapy-induced thrombocytopenia derives from the selective death of megakaryocyte progenitors and can be rescued by stem cell factor

scientific article

Chromosome instability in T-cells cultured in the presence of pancuronium or fentanyl.

scientific article published in September 2004

Combined PDK1 and CHK1 inhibition is required to kill glioblastoma stem-like cells in vitro and in vivo

scientific article

Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51

scientific article published on 02 February 2021

Diagnostic and prognostic potential of the proteomic profiling of serum-derived extracellular vesicles in prostate cancer

scientific article published on 21 June 2021

Drug repurposing for the treatment of glioblastoma multiforme.

scientific article published on 28 November 2017

EGFR inhibition abrogates leiomyosarcoma cell chemoresistance through inactivation of survival pathways and impairment of CSC potential

scientific article

Effect of miR-204&211 and RUNX2 control on the fate of human mesenchymal stromal cells.

scientific article published on 5 December 2017

Exosomes from human colorectal cancer induce a tumor-like behavior in colonic mesenchymal stromal cells

scientific article

Expression of Iron-Related Proteins Differentiate Non-Cancerous and Cancerous Breast Tumors.

scientific article published on 14 February 2017

Gene expression analysis of PTEN positive glioblastoma stem cells identifies DUB3 and Wee1 modulation in a cell differentiation model

scientific article

Gut Mesenchymal Stromal Cells in Immunity

scientific article published on 28 February 2017

Heat shock proteins and their role in heart injury.

scientific article

Homologous control of protein signaling networks.

scientific article published on 23 March 2011

Human neural progenitor cells display limited cytotoxicity and increased oligodendrogenesis during inflammation

scientific article published on 22 December 2006

Identity and ranking of colonic mesenchymal stromal cells

scientific article published on 01 September 2012

Increased HMGB1 expression and release by mononuclear cells following surgical/anesthesia trauma ⬇️

scientific article published on November 2, 2010

Increased death receptor resistance and FLIPshort expression in polycythemia vera erythroid precursor cells.

scientific article published on 29 December 2005

Inhibition of DNA methylation sensitizes glioblastoma for tumor necrosis factor-related apoptosis-inducing ligand-mediated destruction

scientific article published in December 2005

Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma

scientific article published on 05 June 2017

Lymphocyte apoptosis, caspase activation and inflammatory response in septic shock

scientific article published on 13 September 2008

Mesenchymal differentiation of glioblastoma stem cells.

scientific article

Metabolic/Proteomic Signature Defines Two Glioblastoma Subtypes With Different Clinical Outcome.

scientific article published on 9 February 2016

Obesity hormone leptin induces growth and interferes with the cytotoxic effects of 5-fluorouracil in colorectal tumor stem cells.

scientific article published on 16 August 2010

Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases

scientific article published on 27 February 2019

Pancuronium bromide, a non-depolarizing muscle relaxant which promotes apoptosis of blood lymphocytes in vitro.

scientific article published in October 2003

Pharmacological enhancement of mGlu1 metabotropic glutamate receptors causes a prolonged symptomatic benefit in a mouse model of spinocerebellar ataxia type 1.

scientific article published on 19 November 2013

Plasma levels of IL-10 and nitric oxide under two different anaesthesia regimens.

scientific article published in June 2005

Proliferation state and polo-like kinase1 dependence of tumorigenic colon cancer cells.

scientific article

Propranolol enhances cell cycle-related gene expression in pressure overloaded hearts.

scientific article published on December 2011

Proteomic analysis of cerebrospinal fluid from children with central nervous system tumors identifies candidate proteins relating to tumor metastatic spread.

scientific article

Quantum dots for biomedical applications

scientific article

Reverse-phase protein microarrays: application to biomarker discovery and translational medicine.

scientific article published on September 2007

Stem cell factor protects erythroid precursor cells from chemotherapeutic agents via up-regulation of BCL-2 family proteins

scientific article published on 13 March 2003

The Double Face of Exosome-Carried MicroRNAs in Cancer Immunomodulation.

scientific article published on 13 April 2018

The clinical value of patient-derived glioblastoma tumorspheres in predicting treatment response.

scientific article

Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy.

scientific article published on 25 November 2011

UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response.

scientific article

miR-135b suppresses tumorigenesis in glioblastoma stem-like cells impairing proliferation, migration and self-renewal

scientific article published on 30 September 2015

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