List of works - Maurice Médebielle

7-Chloro-4-aminoquinoline γ-hydroxy-γ-lactam derived-tetramates as a new family of antimalarial compounds.

scientific article

A new and efficient method for the synthesis of trifluoromethylthio- and selenoethers

scientific article published on 01 January 2004

Access to cyclic gem-difluoroacyl scaffolds via electrochemical and visible light photocatalytic radical tandem cyclization of heteroaryl chlorodifluoromethyl ketones.

scientific article published in May 2017

An efficient preparation of new sulfonyl fluorides and lithium sulfonates

scientific article published on 31 October 2007

Catalytic Hydrotrifluoromethylation of Unactivated Alkenes

scientific article published on 07 February 2013

Difluoromethylbenzoxazole pyrimidine thioether derivatives: a novel class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors

scientific article

Do advanced glycation end-products play a role in malaria susceptibility?

scientific article

Efficient preparation of new fluorinated lithium and ammonium sulfonimides.

scientific article published on 13 June 2008

Evaluation of ferrocenyl-containing γ-hydroxy-γ-lactam-derived tetramates as potential antiplasmodials

scientific article published in 2022

Incorporation of a 3-(2,2,2-trifluoroethyl)-γ-hydroxy-γ-lactam motif in the side chain of 4-aminoquinolines. Syntheses and antimalarial activities

scientific article published on 18 December 2012

New route to the 5-((arylthio- and heteroarylthio)methylene)-3-(2,2,2-trifluoroethyl)-furan-2(5H)-ones--key intermediates in the synthesis of 4-aminoquinoline γ-lactams as potent antimalarial compounds

scientific article published on 7 September 2013

Novel nucleophilic trifluoromethylation of vicinal diol cyclic sulfates

scientific article published on 01 December 2002

Nucleophilic perfluoroalkylation of aldehydes, ketones, imines, disulfides, and diselenides

scientific article published on 01 April 2006

Nucleophilic trifluoromethylation using trifluoromethyl iodide. A new and simple alternative for the trifluoromethylation of aldehydes and ketones

scientific article published on 01 December 2001

Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery

scientific article published on 07 May 2020

Room-Temperature and Transition-Metal-Free Intramolecular α-Arylation of Ketones: A Mild Access to Tetracyclic Indoles and 7-Azaindoles

scientific article published on 21 December 2018

Studies toward the oxidative and reductive activation of C-S bonds in 2'-S-aryl-2'-thiouridine derivatives.

scientific article published on April 2016

Synthesis and biological evaluation of pyridazinone derivatives as potential anti-inflammatory agents

scientific article published on 17 January 2018

The dual role of thiourea in the thiotrifluoromethylation of alkenes.

scientific article published on 30 September 2016

Trifluoromethylated enaminones and their explorative coordination chemistry with Cu(II): synthesis, redox properties and structural characterization of the complexes

scientific article published on 28 August 2008

Trifluoromethylation of Allylsilanes under Photoredox Catalysis

scientific article published on 06 March 2013

Visible-Light-Mediated Metal-Free Synthesis of Trifluoromethylselenolated Arenes

scientific article published on 01 August 2018

List of works by Maurice Médebielle

7-Chloro-4-aminoquinoline γ-hydroxy-γ-lactam derived-tetramates as a new family of antimalarial compounds.

A new and efficient method for the synthesis of trifluoromethylthio- and selenoethers

Access to cyclic gem-difluoroacyl scaffolds via electrochemical and visible light photocatalytic radical tandem cyclization of heteroaryl chlorodifluoromethyl ketones.

An efficient preparation of new sulfonyl fluorides and lithium sulfonates

Catalytic Hydrotrifluoromethylation of Unactivated Alkenes

Difluoromethylbenzoxazole pyrimidine thioether derivatives: a novel class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors

Do advanced glycation end-products play a role in malaria susceptibility?

Efficient preparation of new fluorinated lithium and ammonium sulfonimides.

Evaluation of ferrocenyl-containing γ-hydroxy-γ-lactam-derived tetramates as potential antiplasmodials

Incorporation of a 3-(2,2,2-trifluoroethyl)-γ-hydroxy-γ-lactam motif in the side chain of 4-aminoquinolines. Syntheses and antimalarial activities

New route to the 5-((arylthio- and heteroarylthio)methylene)-3-(2,2,2-trifluoroethyl)-furan-2(5H)-ones--key intermediates in the synthesis of 4-aminoquinoline γ-lactams as potent antimalarial compounds

Novel nucleophilic trifluoromethylation of vicinal diol cyclic sulfates

Nucleophilic perfluoroalkylation of aldehydes, ketones, imines, disulfides, and diselenides

Nucleophilic trifluoromethylation using trifluoromethyl iodide. A new and simple alternative for the trifluoromethylation of aldehydes and ketones

Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery

Room-Temperature and Transition-Metal-Free Intramolecular α-Arylation of Ketones: A Mild Access to Tetracyclic Indoles and 7-Azaindoles

Studies toward the oxidative and reductive activation of C-S bonds in 2'-S-aryl-2'-thiouridine derivatives.

Synthesis and biological evaluation of pyridazinone derivatives as potential anti-inflammatory agents

The dual role of thiourea in the thiotrifluoromethylation of alkenes.

Trifluoromethylated enaminones and their explorative coordination chemistry with Cu(II): synthesis, redox properties and structural characterization of the complexes

Trifluoromethylation of Allylsilanes under Photoredox Catalysis

Visible-Light-Mediated Metal-Free Synthesis of Trifluoromethylselenolated Arenes